Genomic stress and impaired DNA repair in Alzheimer disease

Authors: Neven, Jolien, Issayama, Luidy Kazuo, Dewachter, Ilse, Wilson, David M., III

Source: In DNA Repair July 2024 139

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

Authors: Wilson, David M., III, Deacon, Ashley M., Duncton, Matthew A.J., Pellicena, Patricia, Georgiadis, Millie M., Yeh, Andrew P., Arvai, Andrew S., Moiani, Davide, Tainer, John A., Das, Debanu

Source: In Progress in Biophysics and Molecular Biology August 2021 163:130-142

DNA damage repair response in mesenchymal stromal cells: From cellular senescence and aging to apoptosis and differentiation ability

Authors: banimohamad-shotorbani, Behnaz, Kahroba, Houman ^*, Sadeghzadeh, Hadi, Wilson, David M., III, Maadi, Hamid, Samadi, Nasser, Hejazi, Mohammad Saeid, Farajpour, Hekmat, Onari, Behzad Nemati, Sadeghi, Mohammad Reza ^*

Source: In Ageing Research Reviews September 2020 62

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging

Authors: Tiwari, Vinod, Wilson, David M., III

Source: In The American Journal of Human Genetics 1 August 2019 105(2):237-257

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

Authors: Lee, Joo Sang, Adler, Lital, Karathia, Hiren, Carmel, Narin, Rabinovich, Shiran, Auslander, Noam, Keshet, Rom, Stettner, Noa, Silberman, Alon, Agemy, Lilach, Helbling, Daniel, Eilam, Raya, Sun, Qin, Brandis, Alexander, Malitsky, Sergey, Itkin, Maxim, Weiss, Hila, Pinto, Sivan, Kalaora, Shelly, Levy, Ronen, Barnea, Eilon, Admon, Arie, Dimmock, David, Stern-Ginossar, Noam, Scherz, Avigdor, Nagamani, Sandesh C.S., Unda, Miguel, Wilson, David M., III, Elhasid, Ronit, Carracedo, Arkaitz, Samuels, Yardena, Hannenhalli, Sridhar, Ruppin, Eytan, Erez, Ayelet

Source: In Cell 6 September 2018 174(6):1559-1570

Coordination of DNA single strand break repair

Authors: Abbotts, Rachel, Wilson, David M., III

Source: In Free Radical Biology and Medicine June 2017 107:228-244

Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome

Authors: Iyama, Teruaki, Wilson, David M., III

Source: In Journal of Molecular Biology 16 January 2016 428(1):62-78

Reduced Nuclease Activity of Apurinic/Apyrimidinic Endonuclease (APE1) Variants on Nucleosomes: IDENTIFICATION OF ACCESS RESIDUES

Authors: Hinz, John M., Mao, Peng, McNeill, Daniel R., Wilson, David M., III

Source: In Journal of Biological Chemistry 21 August 2015 290(34):21067-21075

Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice

Authors: Ghosh, Somnath, Canugovi, Chandrika, Yoon, Jeong Seon, Wilson, David M., III, Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.

Source: In Neurobiology of Aging July 2015 36(7):2319-2330

Protecting the mitochondrial powerhouse

Authors: Scheibye-Knudsen, Morten, Fang, Evandro F., Croteau, Deborah L., Wilson, David M., III, Bohr, Vilhelm A.

Source: In Trends in Cell Biology March 2015 25(3):158-170

A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

Authors: Scheibye-Knudsen, Morten, Mitchell, Sarah J., Fang, Evandro F., Iyama, Teruaki, Ward, Theresa, Wang, James, Dunn, Christopher A., Singh, Nagendra, Veith, Sebastian, Hasan-Olive, Md Mahdi, Mangerich, Aswin, Wilson, Mark A., Mattson, Mark P., Bergersen, Linda H., Cogger, Victoria C., Warren, Alessandra, Le Couteur, David G., Moaddel, Ruin, Wilson, David M., III, Croteau, Deborah L., de Cabo, Rafael, Bohr, Vilhelm A.

Source: In Cell Metabolism 4 November 2014 20(5):840-855

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

Authors: Abdel-Fatah, Tarek M.A., Russell, Roslin, Albarakati, Nada, Maloney, David J., Dorjsuren, Dorjbal, Rueda, Oscar M., Moseley, Paul, Mohan, Vivek, Sun, Hongmao, Abbotts, Rachel, Mukherjee, Abhik, Agarwal, Devika, Illuzzi, Jennifer L., Jadhav, Ajit, Simeonov, Anton, Ball, Graham, Chan, Stephen, Caldas, Carlos, Ellis, Ian O., Wilson, David M., III, Madhusudan, Srinivasan

Source: In Molecular Oncology October 2014 8(7):1326-1338

APE1 Incision Activity at Abasic Sites in Tandem Repeat Sequences

Authors: Li, Mengxia, Völker, Jens, Breslauer, Kenneth J., Wilson, David M., III

Source: In Journal of Molecular Biology 29 May 2014 426(11):2183-2198

Base excision repair in the mammalian brain: Implication for age related neurodegeneration

Authors: Sykora, Peter, Wilson, David M., III, Bohr, Vilhelm A.

Source: In Mechanisms of Ageing and Development October 2013 134(10):440-448

DNA repair mechanisms in dividing and non-dividing cells

Authors: Iyama, Teruaki, Wilson, David M., III

Source: In DNA Repair August 2013 12(8):620-636

Modulation of DNA base excision repair during neuronal differentiation

Authors: Sykora, Peter, Yang, Jenq-Lin, Ferrarelli, Leslie K., Tian, Jingyan, Tadokoro, Takashi, Kulkarni, Avanti, Weissman, Lior, Keijzers, Guido, Wilson, David M., III, Mattson, Mark P., Bohr, Vilhelm A.

Source: In Neurobiology of Aging July 2013 34(7):1717-1727

NEIL1 Responds and Binds to Psoralen-induced DNA Interstrand Crosslinks

Authors: McNeill, Daniel R., Paramasivam, Manikandan, Baldwin, Jakita, Huang, Jing, Vyjayanti, Vaddadi N., Seidman, Michael M., Wilson, David M., III

Source: In Journal of Biological Chemistry 3 May 2013 288(18):12426-12436

Pathways for repairing and tolerating the spectrum of oxidative DNA lesions

Authors: Berquist, Brian R., Wilson, David M., III

Source: In Cancer Letters 31 December 2012 327(1-2):61-72

The Interaction between Polynucleotide Kinase Phosphatase and the DNA Repair Protein XRCC1 Is Critical for Repair of DNA Alkylation Damage and Stable Association at DNA Damage Sites

Authors: Della-Maria, Julie, Hegde, Muralidhar L., McNeill, Daniel R., Matsumoto, Yoshihiro, Tsai, Miaw-Sheue ^**, Ellenberger, Tom, Wilson, David M., III, Mitra, Sankar, Tomkinson, Alan E.

Source: In Journal of Biological Chemistry 9 November 2012 287(46):39233-39244

The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1

Authors: Hanssen-Bauer, Audun, Solvang-Garten, Karin, Gilljam, Karin Margaretha, Torseth, Kathrin, Wilson, David M., III, Akbari, Mansour, Otterlei, Marit

Source: In DNA Repair 1 April 2012 11(4):357-366