Intraparenchymal near-infrared spectroscopy for detection of delayed cerebral ischemia in poor-grade aneurysmal subarachnoid hemorrhage

Authors: Willms, Jan F., Boss, Jens M., Huo, Shufan, Wolf, Stefan, Westphal, Laura P., Bögli, Stefan Y., Inauen, Corinne, Baumann, Dirk, Fröhlich, Jürg, Keller, Emanuela

Source: In Journal of Neuroscience Methods June 2024 406

Functional NIRS to detect covert consciousness in neurocritical patients

Authors: Bicciato, Giulio, Narula, Gagan, Brandi, Giovanna, Eisele, Amanda, Schulthess, Sven, Friedl, Susanne, Willms, Jan Folkard, Westphal, Laura, Keller, Emanuela

Source: In Clinical Neurophysiology December 2022 144:72-82

ICU Cockpit: a platform for collecting multimodal waveform data, AI-based computational disease modeling and real-time decision support in the intensive care unit

Authors: Boss, Jens Michael, Narula, Gagan, Straessle, Christian, Willms, Jan, Azzati, Jan, Brodbeck, Dominique, Luethy, Rahel, Suter, Susanne, Buehler, Christof, Muroi, Carl, Mack, David Jule, Seric, Marko, Baumann, Daniel, Keller, Emanuela

Source: Journal of the American Medical Informatics Association. 29(7):1286-1291

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155612086.0x000001&indx=1&recIds=ETOCvdc_100155612086.0x000001

A Longitudinal Model for a Dynamic Risk Score to Predict Delayed Cerebral Ischemia after Subarachnoid Hemorrhage.

Authors: Willms, Jan F.¹ (AUTHOR) janfolkard.willms@usz.ch, Inauen, Corinne² (AUTHOR) corinne.inauen@usz.ch, Bögli, Stefan Yu² (AUTHOR) stefanyu.boegli@usz.ch, Muroi, Carl¹ (AUTHOR) jensmichael.boss@usz.ch, Boss, Jens M.¹ (AUTHOR) emanuela.keller@icucockpit.ch, Keller, Emanuela¹ (AUTHOR)

Source: Bioengineering (Basel). Oct2024, Vol. 11 Issue 10, p988. 13p.

Subject Terms: *MACHINE learning, *DISEASE risk factors, *SUBARACHNOID hemorrhage, *CEREBRAL ischemia, *RECEIVER operating characteristic curves

Large and Small Cerebral Vessel Involvement in Severe COVID-19

Authors: Keller, Emanuela, Brandi, Giovanna, Winklhofer, Sebastian, Imbach, Lukas L., Kirschenbaum, Daniel, Frontzek, Karl, Steiger, Peter, Dietler, Sabeth, Haeberlin, Marcellina, Willms, Jan, Porta, Francesca, Waeckerlin, Adrian, Huber, Michael, Abela, Irene A., Lutterotti, Andreas, Stippich, Christoph, Globas, Christoph, Varga, Zsuzsanna, Jelcic, Ilijas

Source: Stroke. 51(12):3719-3722

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175323616.0x000001&indx=1&recIds=ETOCvdc_100175323616.0x000001

A supervised, externally validated machine learning model for artifact and drainage detection in high-resolution intracranial pressure monitoring data.

Authors: Shufan Huo, Nelde, Alexander, Meisel, Christian, Scheibe, Franziska, Meisel, Andreas, Endres, Matthias, Vajkoczy, Peter, Wolf, Stefan, Willms, Jan F., Boss, Jens M., Keller, Emanuela

Source: Journal of Neurosurgery; Aug2024, Vol. 141 Issue 2, p509-517, 9p

Low frequency oscillations reflect neurovascular coupling and disappear after cerebral death.

Authors: Schulthess, Sven, Friedl, Susanne, Narula, Gagan, Brandi, Giovanna, Willms, Jan Folkard, Keller, Emanuela, Bicciato, Giulio

Source: Scientific Reports; 5/17/2024, Vol. 14 Issue 1, p1-10, 10p

Subject Terms: BRAIN death, RESPIRATION, NEAR infrared spectroscopy, CONSCIOUSNESS disorders, POWER spectra, ACOUSTIC stimulation

Predicting outcome after aneurysmal subarachnoid hemorrhage by exploitation of signal complexity: a prospective two-center cohort study.

Authors: Bögli, Stefan Yu, Olakorede, Ihsane, Veldeman, Michael, Beqiri, Erta, Weiss, Miriam, Schubert, Gerrit Alexander, Willms, Jan Folkard, Keller, Emanuela, Smielewski, Peter

Source: Critical Care; 5/14/2024, Vol. 28 Issue 1, p1-12, 12p

OxyHbMeter--a novel bedside medical device for monitoring cell-free hemoglobin in the cerebrospinal fluid--proof of principle.

Authors: Tachatos, Nikolaos, Willms, Jan Folkard, Gerlt, Michael Sebastian, Kuruvithadam, Kiran, Hugelshofer, Michael, Akeret, Kevin, Deuel, Jeremy, Keller, Emanuela, Daners, Marianne Schmid

Source: Frontiers in Medical Technology; 2024, p1-9, 9p

Subject Terms: CEREBROSPINAL fluid examination, IN vitro studies, SWINE, CENTRIFUGATION, RESEARCH funding, SUBARACHNOID hemorrhage, HEMOGLOBINS, ANIMALS, HOSPITAL patients, PLASMAPHERESIS, MICROFLUIDIC analytical techniques, ROOMS, MEDICAL equipment, ANIMAL experimentation, CEREBRAL ischemia, POINT-of-care testing, CELL separation, BIOMARKERS, TIME, SPECTROPHOTOMETRY, DISEASE risk factors, DISEASE complications

Evaluation of machine learning algorithms for noninvasive intracranial pressure estimation using near infrared spectroscopy as a covariate.

Authors: Narula, Gagan, Boss, Jens, Seric, Marko, Baumann, Daniel, Salles, Joan P., Fröhlich, Jürg, Baumann, Dirk, Keller, Emanuela, Willms, Jan

Source: Technology & Health Care; 2024, Vol. 32 Issue 2, p937-949, 13p

Subject Terms: NEAR infrared spectroscopy, MACHINE learning, INTRACRANIAL pressure, INTRACRANIAL hypertension, BRAIN injuries

Thrombocyte transfusion and rebleeding rate in patients using antiplatelet agents before aneurysmal subarachnoid hemorrhage.

Authors: Sebök, Martina, Zaugg, Natalie, Keller, Emanuela, Willms, Jan, Regli, Luca, Germans, Menno

Source: Neurosurgical Focus; Oct2023, Vol. 55 Issue 4, p1-7, 7p

Reocclusion after successful endovascular treatment in acute ischemic stroke: systematic review and metaanalysis.

Authors: Madjidyar, Jawid, Keller, Emanuela, Winklhofer, Sebastian, Toth, Daniel, Barnaure, Isabelle, Schubert, Tilman, Thurner, Patrick, Fierstra, Jorn, Willms, Jan Folkard, Kulcsar, Zsolt

Source: Journal of NeuroInterventional Surgery; Oct2023, Vol. 15 Issue 10, p964-970, 8p

Subject Terms: ATHEROSCLEROSIS complications, MORTALITY risk factors, ARTERIAL occlusions, ONLINE information services, META-analysis, ISCHEMIC stroke, SYSTEMATIC reviews, FUNCTIONAL status, SURGICAL complications, DISEASE incidence, THROMBOLYTIC therapy, DISEASE relapse, RISK assessment, TREATMENT effectiveness, THROMBECTOMY, ENDOVASCULAR surgery, MEDLINE, DISEASE risk factors

Single- antiplatelet regimen in ruptured cerebral blood blister and dissecting aneurysms treated with flowdiverter stent reconstruction.

Authors: Madjidyar, Jawid, Keller, Emanuela, Winklhofer, Sebastian, Toth, Daniel, Barnaure, Isabelle, Schubert, Tilman, Fierstra, Jorn, Willms, Jan Folkard, Regli, Luca, Kulcsar, Zsolt

Source: Journal of NeuroInterventional Surgery; Oct2023, Vol. 15 Issue 10, p953-957, 6p

Subject Terms: INTRACRANIAL aneurysm surgery, PROSTHETICS, INTRAVENOUS therapy, ORAL drug administration, SURGICAL stents, ARTIFICIAL implants, RETROSPECTIVE studies, ACQUISITION of data, ANTICOAGULANTS, TREATMENT effectiveness, EPTIFIBATIDE, SUBARACHNOID hemorrhage, PLATELET aggregation inhibitors, MEDICAL records, DESCRIPTIVE statistics, HEPARIN, INTRACRANIAL aneurysms, DISEASE complications, EVALUATION

Solving the explainable AI conundrum by bridging clinicians' needs and developers' goals.

Authors: Bienefeld, Nadine, Boss, Jens Michael, Lüthy, Rahel, Brodbeck, Dominique, Azzati, Jan, Blaser, Mirco, Willms, Jan, Keller, Emanuela

Source: NPJ Digital Medicine; 5/22/2023, Vol. 6 Issue 1, p1-7, 7p

Subject Terms: COMPUTER simulation, PROBLEM solving, CLINICAL decision support systems, RESEARCH methodology, ARTIFICIAL intelligence, PSYCHOLOGY, HUMAN services programs, CONCEPTUAL structures, SURVEYS, DESCRIPTIVE statistics, CONCEPTUAL models, RESEARCH funding, NEEDS assessment, DATA analysis software, GOAL (Psychology), LONGITUDINAL method

Spontaneous empyema and brain abscess in an intensive care population: clinical presentation, microbiology, and factors associated with outcome.

Authors: Dietler, Sabeth¹ (AUTHOR) Sabeth.dietler@usz.ch, Willms, Jan¹ (AUTHOR), Brandi, Giovanna¹ (AUTHOR), Wang, Sophie¹ (AUTHOR), Burkerth, Astrid¹ (AUTHOR), Keller, Emanuela² (AUTHOR)

Source: Acta Neurochirurgica. Mar2023, Vol. 165 Issue 3, p651-658. 8p.

Subject Terms: *BRAIN abscess, *EMPYEMA, *SYMPTOMS, *CRITICAL care medicine, *MICROBIOLOGY, *CLINICAL medicine, *GLASGOW Coma Scale

Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.

Authors: Jarius, Sven, Pache, Florence, Körtvelyessy, Peter, Jelčić, Ilijas, Stettner, Mark, Franciotta, Diego, Keller, Emanuela, Neumann, Bernhard, Ringelstein, Marius, Senel, Makbule, Regeniter, Axel, Kalantzis, Rea, Willms, Jan F., Berthele, Achim, Busch, Markus, Capobianco, Marco, Eisele, Amanda, Reichen, Ina, Dersch, Rick, Rauer, Sebastian

Source: Journal of Neuroinflammation; Dec2022, Vol. 19 Issue 1, p1-33, 33p

Subject Terms: IMMUNE reconstitution inflammatory syndrome, ANTI-NMDA receptor encephalitis, CEREBROSPINAL fluid, SARS-CoV-2, COVID-19, POST-acute COVID-19 syndrome, LUMBAR puncture

Single-antiplatelet regimen in ruptured cerebral blood blister and dissecting aneurysms treated with flow-diverter stent reconstruction

Authors: Madjidyar, Jawid, Keller, Emanuela, Winklhofer, Sebastian, Toth, Daniel, Barnaure, Isabelle, Schubert, Tilman, Thurner, Patrick, Fierstra, Jorn, Willms, Jan Folkard, Regli, Luca, Kulcsar, Zsolt

Source: Journal of Neurointerventional Surgery; 2023, Vol. 15 Issue: 10 p953-957, 5p

Functional relationship of arterial blood pressure, central venous pressure and intracranial pressure in the early phase after subarachnoid hemorrhage.

Authors: Maissen, Gabriela, Narula, Gagan, Strässle, Christian, Willms, Jan, Muroi, Carl, Keller, Emanuela

Source: Technology & Health Care; 2022, Vol. 30 Issue 3, p591-604, 14p

Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury.

Authors: Akeret, Kevin, Buzzi, Raphael M, Schaer, Christian A, Thomson, Bart R, Vallelian, Florence, Wang, Sophie, Willms, Jan, Sebök, Martina, Held, Ulrike, Deuel, Jeremy W, Humar, Rok, Regli, Luca, Keller, Emanuela, Hugelshofer, Michael, Schaer, Dominik J

Source: Journal of Cerebral Blood Flow & Metabolism; Nov2021, Vol. 41 Issue 11, p3000-3015, 16p

The effect of nimodipine on pulmonary function in artificially ventilated patients with aneurysmal subarachnoid hemorrhage.

Authors: Lunkiewicz, Justyna, Brandi, Giovanna, Willms, Jan, Strässle, Christian, Narula, Gagan, Keller, Emanuela, Muroi, Carl

Source: Acta Neurochirurgica; Oct2021, Vol. 163 Issue 10, p2715-2721, 7p

Subject Terms: SUBARACHNOID hemorrhage, NIMODIPINE, RESPIRATORY infections, PARTIAL pressure, LUNGS