Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design

Authors: Xiao, Ganyuan, Alphey, Magnus S., Tran, Fanny, Pirrie, Lisa, Milbeo, Pierre, Zhou, Yi, Bickel, Jasmine K., Kempf, Oxana, Kempf, Karl, Naismith, James H., Westwood, Nicholas J.

Source: In Bioorganic & Medicinal Chemistry 15 November 2021 50

Analysis of the product streams obtained on butanosolv pretreatment of draff

Authors: Foltanyi, Flora, Hawkins, Julie E., Panovic, Isabella, Bird, Eve J., Gloster, Tracey M., Lancefield, Christopher S., Westwood, Nicholas J.

Source: In Biomass and Bioenergy October 2020 141

Catalytic depolymerisation of isolated lignin to fine chemicals: Depolymerisation of Kraft lignin

Authors: Munick de Albuquerque Fragoso, Danielle, Bouxin, Florent P., Montgomery, James R.D., Westwood, Nicholas J., Jackson, S. David

Source: In Bioresource Technology Reports February 2020 9

Discovery of novel enzyme genes involved in the conversion of an arylglycerol-β-aryl ether metabolite and their use in generating a metabolic pathway for lignin valorization

Authors: Higuchi, Yudai, Kato, Ryo, Tsubota, Koichiro, Kamimura, Naofumi, Westwood, Nicholas J., Masai, Eiji

Source: In Metabolic Engineering September 2019 55:258-267

Copper‐Mediated Conversion of Complex Ethers to Esters: Enabling Biopolymer Depolymerisation under Mild Conditions

Authors: Xiao, Ganyuan, Montgomery, James R. D., Lancefield, Christopher S., Panovic, Isabella, Westwood, Nicholas J.

Source: Chemistry. 26(54):12397-12402

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195601261.0x000001&indx=1&recIds=ETOCvdc_100195601261.0x000001

From one to two quaternary centers: Ester or nitrile α-alkylation applied to bioactive alkaloids

Authors: Voute, Nicholas, Neal, Andrew R., Medda, Federico, Johnston, Craig A., Slawin, Alexandra M.Z., Westwood, Nicholas J.

Source: In Tetrahedron 27 December 2018 74(52):7399-7407

Valorisation strategies for cocoa pod husk and its fractions

Authors: Lu, Fei, Rodriguez-Garcia, Julia, Van Damme, Isabella, Westwood, Nicholas J., Shaw, Liz, Robinson, James S., Warren, Geoff, Chatzifragkou, Afroditi, McQueen Mason, Simon, Gomez, Leonardo, Faas, Laura, Balcombe, Kelvin, Srinivasan, Chittur, Picchioni, Fiorella, Hadley, Paul, Charalampopoulos, Dimitris

Source: In Current Opinion in Green and Sustainable Chemistry December 2018 14:80-88

Polycyclic ethers and an unexpected dearomatisation reaction during studies towards the bioactive alkaloid, perophoramidine

Authors: Johnston, Craig A., Wilkie, Ross P., Krauss, Helmut, Neal, Andrew R., Slawin, Alexandra M.Z., Lebl, Tomas, Westwood, Nicholas J.

Source: In Tetrahedron 28 June 2018 74(26):3339-3347

Assessment of the regioselectivity in the condensation reaction of unsymmetrical o-phthaldialdehydes with alanine

Authors: D'Hollander, Agathe C.A., Westwood, Nicholas J.

Source: In Tetrahedron 11 January 2018 74(2):224-239

Using Fractionation and Diffusion Ordered Spectroscopy to Study Lignin Molecular Weight.

Authors: Montgomery, James R. D., Bazley, Priory, Lebl, Tomas, Westwood, Nicholas J.

Source: ChemistryOpen. 8(5):601-605

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143452718.0x000001&indx=1&recIds=ETOCvdc_100143452718.0x000001

Is oxidation–reduction a real robust strategy for lignin conversion? A comparative study on lignin and model compoundsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8gc02670j

Authors: Guo, Haiwei, Miles-Barrett, Daniel M., Zhang, Bo, Wang, Aiqin, Zhang, Tao, Westwood, Nicholas J., Li, Changzhi

Source: Green chemistry. 21(4):803-811

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100076590853.0x000001&indx=1&recIds=ETOCvdc_100076590853.0x000001

Selective Depolymerisation of γ‐Oxidised Lignin via NHC Catalysed Redox Esterification

Authors: Xiao, Ganyuan, Lancefield, Christopher S., Westwood, Nicholas J.

Source: ChemCatChem. 11(14):3182-3186

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085850799.0x000001&indx=1&recIds=ETOCvdc_100085850799.0x000001

Chemical Genetics: How Does It Function?

Authors: Westwood, Nicholas J.

Source: Philosophical Transactions: Mathematical, Physical and Engineering Sciences, 2004 Dec . 362(1825), 2761-2774.

Access URL: https://www.jstor.org/stable/4142323

A Small-Molecule Approach to Studying Invasive Mechanisms of Toxoplasma gondii

Authors: Carey, Kimberly L., Westwood, Nicholas J., Mitchison, Timothy J., Ward, Gary E., Miller, Louis H.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 May 01. 101(19), 7433-7438.

Access URL: https://www.jstor.org/stable/3371883

Formation of Nanodiamonds during Pyrolysis of Butanosolv Lignin

Authors: Feng, Yi, Davidson, Daniel J., Sun, Weihao, Milani, Valentina, Howieson, Grant W., Westwood, Nicholas J., Zhou, Wuzong

Source: ACS Nano; September 2024, Vol. 18 Issue: 36 p24803-24811, 9p

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

Authors: Tatham, Michael H. ^‡, Cole, Christian ^§, Scullion, Paul ^¶, Wilkie, Ross ^{‖, ‡‡}, Westwood, Nicholas J. ^‖, Stark, Lesley A. ^**, Hay, Ronald T. ^{‡, §§}

Source: In Molecular & Cellular Proteomics February 2017 16(2):310-326

MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii.

Authors: Kelsen, Anne¹, Kent, Robyn S.¹, Snyder, Anne K.¹, Wehri, Eddie², Bishop, Stephen J.³, Stadler, Rachel V.¹, Powell, Cameron⁴, Martorelli di Genova, Bruno¹, Rompikuntal, Pramod K.¹, Boulanger, Martin J.⁴, Warshaw, David M.⁵, Westwood, Nicholas J.³, Schaletzky, Julia², Ward, Gary E.¹, Gary.Ward@uvm.edu

Source: PLoS Biology; 5/8/2023, Vol. 21 Issue 5, p1-36, 36p, 3 Color Photographs, 1 Black and White Photograph, 5 Graphs

Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling

Alternate Title: Identifying Modulators of Apicomplexan Ca2+ Signaling (English)

Authors: Sidik, Saima M., Hortua Triana, Miryam A., Paul, Aditya S., El Bakkouri, Majida, Hackett, Caroline G., Tran, Fanny ^**, Westwood, Nicholas J. ^**, Hui, Raymond, Zuercher, William J., Duraisingh, Manoj T., Moreno, Silvia N.J., Lourido, Sebastian

Source: In Journal of Biological Chemistry 29 April 2016 291(18):9566-9580

Metal Triflates for the Production of Aromatics from Lignin

Authors: Deuss, Peter J., Lahive, Ciaran W., Lancefield, Christopher S., Westwood, Nicholas J., Kamer, Paul C. J., Barta, Katalin, de Vries, Johannes G.

Source: ChemSusChem. 9(20):2974-2981

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081736617.0x000001&indx=1&recIds=ETOCvdc_100081736617.0x000001

The Covalent Linking of Organophosphorus Heterocycles to Date Palm Wood-Derived Lignin: Hunting for New Materials with Flame-Retardant Potential.

Authors: Davidson, Daniel J., McKay, Aidan P., Cordes, David B., Woollins, J. Derek, Westwood, Nicholas J.

Source: Molecules; Dec2023, Vol. 28 Issue 23, p7885, 15p

Subject Terms: DATE palm, FIREPROOFING agents, LIGNIN structure, LIGNINS, ALKALINE hydrolysis, X-ray crystallography, HETEROCYCLIC compounds