A framework for longitudinal latent factor modelling of treatment response in clinical trials with applications to Psoriatic Arthritis and Rheumatoid Arthritis

Authors: Falck, Fabian, Zhu, Xuan, Ghalebikesabi, Sahra, Kormaksson, Matthias, Vandemeulebroecke, Marc, Zhang, Cong, Martin, Ruvie, Gardiner, Stephen, Kwok, Chun Hei, West, Dominique M., Santos, Luis, Tian, Chengeng, Pang, Yu, Readie, Aimee, Ligozio, Gregory, Gandhi, Kunal K., Nichols, Thomas E., Mallon, Ann-Marie, Kelly, Luke, Ohlssen, David, Nicholson, George

Source: In Journal of Biomedical Informatics June 2024 154

Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy

Authors: Tadros, Rafik, Zheng, Sean L., Grace, Christopher, Jordà, Paloma, Francis, Catherine, West, Dominique M., Jurgens, Sean J., Thomson, Kate L., Harper, Andrew R., Ormondroyd, Elizabeth, Xu, Xiao, Theotokis, Pantazis I., Buchan, Rachel J., McGurk, Kathryn A., Mazzarotto, Francesco, Boschi, Beatrice, Pelo, Elisabetta, Lee, Michael, Noseda, Michela, Varnava, Amanda, Vermeer, Alexa M. C., Walsh, Roddy, Amin, Ahmad S., van Slegtenhorst, Marjon A., Roslin, Nicole M., Strug, Lisa J., Salvi, Erika, Lanzani, Chiara, de Marvao, Antonio, Roberts, Jason D., Tremblay-Gravel, Maxime, Giraldeau, Genevieve, Cadrin-Tourigny, Julia, L’Allier, Philippe L., Garceau, Patrick, Talajic, Mario, Gagliano Taliun, Sarah A., Pinto, Yigal M., Rakowski, Harry, Pantazis, Antonis, Bai, Wenjia, Baksi, John, Halliday, Brian P., Prasad, Sanjay K., Barton, Paul J. R., O’Regan, Declan P., Cook, Stuart A., de Boer, Rudolf A., Christiaans, Imke, Michels, Michelle, Kramer, Christopher M., Ho, Carolyn Y., Neubauer, Stefan, Matthews, Paul M., Wilde, Arthur A. M., Tardif, Jean-Claude, Olivotto, Iacopo, Adler, Arnon, Goel, Anuj, Ware, James S., Bezzina, Connie R., Watkins, Hugh

Source: Nature Genetics; March 2025, Vol. 57 Issue: 3 p530-538, 9p

Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis.

Authors: Mallon, Ann-Marie, Häring, Dieter A., Dahlke, Frank, Aarden, Piet, Afyouni, Soroosh, Delbarre, Daniel, El Emam, Khaled, Ganjgahi, Habib, Gardiner, Stephen, Kwok, Chun Hei, West, Dominique M., Straiton, Ewan, Haemmerle, Sibylle, Huffman, Adam, Hofmann, Tom, Kelly, Luke J., Krusche, Peter, Laramee, Marie-Claude, Lheritier, Karine, Ligozio, Greg

Source: BMC Medical Research Methodology; 11/13/2021, Vol. 21 Issue 1, p1-11, 11p

Subject Terms: INFORMATION sharing, DATA science, DRUG development, PSORIATIC arthritis, STATISTICS, MEDICAL personnel

Company/Entity: UNIVERSITY of Oxford, NOVARTIS AG