RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses

Authors: Gustavsson, Emil K, Follett, Jordan, Trinh, Joanne, Barodia, Sandeep K, Real, Raquel, Liu, Zhiyong, Grant-Peters, Melissa, Fox, Jesse D, Appel-Cresswell, Silke, Stoessl, A Jon, Rajput, Alex, Rajput, Ali H, Auer, Roland, Tilney, Russel, Sturm, Marc, Haack, Tobias B, Lesage, Suzanne, Tesson, Christelle, Brice, Alexis, Vilariño-Güell, Carles, Ryten, Mina, Goldberg, Matthew S, West, Andrew B, Hu, Michele T, Morris, Huw R, Sharma, Manu, Gan-Or, Ziv, Samanci, Bedia, Lis, Pawel, Periñan, Maria Teresa, Amouri, Rim, Ben Sassi, Samia, Hentati, Faycel, Tonelli, Francesca, Alessi, Dario R, Farrer, Matthew J ^*

Source: In The Lancet Neurology June 2024 23(6):603-614

LRRK2‐Targeting Therapies March Through the Valley of Death

Authors: West, Andrew B., Schwarzschild, Michael A.

Source: Movement disorders. 38(3):361-365

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182083645.0x000001&indx=1&recIds=ETOCvdc_100182083645.0x000001

Who to Enroll in Parkinson Disease Prevention Trials?

Authors: Niotis, Kellyann, West, Andrew B., Saunders-Pullman, Rachel

Source: Neurology. 99(7 Supplement 1):10-18

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168977319.0x000001&indx=1&recIds=ETOCvdc_100168977319.0x000001

Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease

Authors: Wang, Shijie, Unnithan, Shakthi, Bryant, Nicole, Chang, Allison, Rosenthal, Liana S., Pantelyat, Alexander, Dawson, Ted M., Al‐Khalidi, Hussein R., West, Andrew B.

Source: Movement disorders. 37(7):1454-1464

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168959169.0x000001&indx=1&recIds=ETOCvdc_100168959169.0x000001

Lewy body diseases and the gut.

Authors: Sampson, Timothy R., Tansey, Malú Gámez, West, Andrew B., Liddle, Rodger A.

Source: Molecular Neurodegeneration; 1/30/2025, Vol. 20 Issue 1, p1-18, 18p

Subject Terms: LEWY body dementia, PARKINSON'S disease, MEDICAL sciences, INTESTINAL mucosa, GASTROINTESTINAL system

Dopaminergic neurodegeneration induced by Parkinson’s disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity

Authors: Nguyen, An Phu Tran, Tsika, Elpida, Kelly, Kaela, Levine, Nathan, Chen, Xi, West, Andrew B., Boularand, Sylviane, Barneoud, Pascal, Moore, Darren J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(29), 17296-17307.

Access URL: https://www.jstor.org/stable/26935437

Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain

Authors: Kelly, Kaela, Chang, Allison, Hastings, Lyndsay, Abdelmotilib, Hisham, West, Andrew B.

Source: In Brain Research 15 May 2021 1759

Identification of LRRK2 missense variants in the accelerating medicines partnership Parkinson's disease cohort

Authors: Bryant, Nicole, Malpeli, Nicole, Ziaee, Julia, Blauwendraat, Cornelis, Liu, Zhiyong, West, Andrew B

Source: Human molecular genetics. 30(6):454-466

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135731690.0x000001&indx=1&recIds=ETOCvdc_100135731690.0x000001

Proteomic analysis of urinary extracellular vesicles reveal biomarkers for neurologic disease

Authors: Wang, Shijie, Kojima, Kyoko, Mobley, James A., West, Andrew B.

Source: In EBioMedicine July 2019 45:351-361

Virtual Microscopy Is More Effective Than Conventional Microscopy for Teaching Cytology to Veterinary Students: A Randomized Controlled Trial

Authors: Evans, Samantha J. M., Moore, A. Russell, Olver, Christine S., Avery, Paul R., West, Andrew B.

Source: Journal of veterinary medical education. 47(4):475-481

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625955115&indx=1&recIds=ETOCRN625955115

Veterinary Educator Teaching and Scholarship (VETS): A Case Study of a Multi-Institutional Faculty Development Program to Advance Teaching and Learning

Authors: Gordon-Ross, Paul N., Kovacs, Suzie J., Halsey, Rachel L., West, Andrew B., Smith, Martin H.

Source: Journal of veterinary medical education. 47(5):632-646

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625976205&indx=1&recIds=ETOCRN625976205

Perspectives in Veterinary Education Student, faculty, and program outcomes associated with capstone examinations administered to veterinary students at Colorado State University

Authors: Avery, Anne C., Dowers, Kristy L., West, Andrew B., Graham, Barbara J., Hellyer, Peter, Avery, Paul R., Ballweber, Lora R., Hassel, Diana M., Oaks, James F., Frye, Melinda A.

Source: Journal of the American Veterinary Medical Association. 257(2):165-175

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624236117&indx=1&recIds=ETOCRN624236117

A Competency-Guided Veterinary Curriculum Review Process

Authors: Varnum, Angela T., West, Andrew B., Hendrickson, Dean A.

Source: Journal of veterinary medical education. 47(2):137-147

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623721928&indx=1&recIds=ETOCRN623721928

The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition

Authors: Kelly, Kaela, Wang, Shijie, Boddu, Ravindra, Liu, Zhiyong, Moukha-Chafiq, Omar, Augelli-Szafran, Corinne, West, Andrew B.

Source: In Experimental Neurology November 2018 309:1-13

LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model

Authors: Zhao, Hien Tran, John, Neena, Delic, Vedad, Ikeda-Lee, Karli, Kim, Aneeza, Weihofen, Andreas, Swayze, Eric E., Kordasiewicz, Holly B., West, Andrew B., Volpicelli-Daley, Laura A.

Source: Molecular therapy.Nucleic acids. 25:152-154

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142214437.0x000001&indx=1&recIds=ETOCvdc_100142214437.0x000001

Identification of Novel α‐Synuclein Assemblies in Lewy Body Disease

Authors: Sokratian, Arpine, Gram, Hjalte, Jensen, Poul H., West, Andrew B.

Source: Movement disorders. 38(1):21-22

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171684720.0x000001&indx=1&recIds=ETOCvdc_100171684720.0x000001

Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease

Authors: West, Andrew B.

Source: In Experimental Neurology December 2017 298 Part B:236-245

LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model

Authors: Zhao, Hien Tran, John, Neena, Delic, Vedad, Ikeda-Lee, Karli, Kim, Aneeza, Weihofen, Andreas, Swayze, Eric E., Kordasiewicz, Holly B., West, Andrew B., Volpicelli-Daley, Laura A.

Source: In Molecular Therapy - Nucleic Acids 15 September 2017 8:508-519

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF)

Authors: Ivanova, Anna A., Caspary, Tamara, Seyfried, Nicholas T., Duong, Duc M., West, Andrew B., Liu, Zhiyong, Kahn, Richard A.

Source: In Journal of Biological Chemistry 30 June 2017 292(26):11091-11108

Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation.

Authors: Yuan, Yuan, Li, Huizhong, Sreeram, Kashyap, Malankhanova, Tuyana, Boddu, Ravindra, Strader, Samuel, Chang, Allison, Bryant, Nicole, Yacoubian, Talene A., Standaert, David G., Erb, Madalynn, Moore, Darren J., Sanders, Laurie H., Lutz, Michael W., Velmeshev, Dmitry, West, Andrew B.

Source: Molecular Neurodegeneration; 6/11/2024, Vol. 19 Issue 1, p1-23, 23p

Subject Terms: PARKINSON'S disease, DARDARIN, SINGLE molecules, DEEP brain stimulation, INFLAMMATION, KNOCKOUT mice, NEUTROPHILS