iPLA2β loss leads to age-related cognitive decline and neuroinflammation by disrupting neuronal mitophagy

Authors: Li Jiao, Wenxin Shao, Wenqi Quan, Longjiang Xu, Penghui Liu, Jinling Yang, Xiaozhong Peng

Source: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/c25a53b1fd6f490bbc74f580ae833541

A physiologically‐based pharmacokinetic/pharmacodynamic modeling approach for drug–drug‐gene interaction evaluation of S‐warfarin with fluconazole

Authors: Kuo Geng, Chaozhuang Shen, Xiaohu Wang, Xingwen Wang, Wenxin Shao, Wenhui Wang, Tao Chen, Hua Sun, Haitang Xie

Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 5, Pp 853-869 (2024)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2163-8306

Access URL: https://doaj.org/article/bc477cb1364e4e1cb94d302dd4ad816c

Schisandrin protects against ulcerative colitis by inhibiting the SGK1/NLRP3 signaling pathway and reshaping gut microbiota in mice

Authors: Xiaohu Wang, Chaozhuang Shen, Xingwen Wang, Jin Tang, Zijing Wu, Yunzhe Huang, Wenxin Shao, Kuo Geng, Haitang Xie, Zhichen Pu

Source: Chinese Medicine, Vol 18, Iss 1, Pp 1-16 (2023)

Subject Terms: Schisandra chinensis (Turcz.) Baill., Schisandrin, Ulcerative colitis, NLRP3, Gut microbiota, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8546

Access URL: https://doaj.org/article/66c672a6e946411ba2233686a1b82293

Physiologically based pharmacokinetic modeling of levetiracetam to predict the exposure in hepatic and renal impairment and elderly populations

Authors: Chaozhuang Shen, Wenxin Shao, Wenhui Wang, Hua Sun, Xiaohu Wang, Kuo Geng, Xingwen Wang, Haitang Xie

Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 7, Pp 1001-1015 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2163-8306

Access URL: https://doaj.org/article/671b474fb6b643abb41180d53333ea11

Predictive performance and verification of physiologically based pharmacokinetic model of propylthiouracil

Authors: Chaozhuang Shen, Dahu Liang, Xiaohu Wang, Wenxin Shao, Kuo Geng, Xingwen Wang, Hua Sun, Haitang Xie

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: propylthiouracil (PTU), PBPK, PK-sim®, extrapolation, elderly, pediatric, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1013432/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/85bc310349f5475a91a69e2fc10e6398

Spectrin-based membrane skeleton supports ciliogenesis.

Authors: Ru Jia, Dongdong Li, Ming Li, Yongping Chai, Yufan Liu, Zhongyun Xie, Wenxin Shao, Chao Xie, Liuju Li, Xiaoshuai Huang, Liangyi Chen, Wei Li, Guangshuo Ou

Source: PLoS Biology, Vol 17, Iss 7, p e3000369 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/d89f26bc25fe469aa3002aa5e957c556

Tetraaquabis[4-(4H-1,2,4-triazol-4-yl)benzoato-κN1]copper(II) dihydrate

Authors: Shuzhi Xu, Wenxin Shao, Miao Yu, Guihua Gong

Source: Acta Crystallographica Section E, Vol 67, Iss 6, Pp m777-m777 (2011)

Subject Terms: Crystallography, QD901-999

File Description: electronic resource

Relation: http://scripts.iucr.org/cgi-bin/paper?S1600536811018356; https://doaj.org/toc/1600-5368

Access URL: https://doaj.org/article/fa1c06e8f8e54e7388b5141f193682f0

Diaquabis[4-(4H-1,2,4-triazol-4-yl)benzoato-κ2O,O′]nickel(II)

Authors: Shuzhi Xu, Wenxin Shao, Miao Yu, Guihua Gong

Source: Acta Crystallographica Section E, Vol 67, Iss 6, Pp m728-m728 (2011)

Subject Terms: Crystallography, QD901-999

File Description: electronic resource

Relation: http://scripts.iucr.org/cgi-bin/paper?S1600536811016643; https://doaj.org/toc/1600-5368

Access URL: https://doaj.org/article/1c0da8557c084a23b9f87582f03d596f

DYF-5/MAK-dependent phosphorylation promotes ciliary tubulin unloading.

Authors: Xuguang Jiang¹, Wenxin Shao¹, Yongping Chai¹, Jingying Huang¹, Mohamed, Mohamed A. A.², Ökten, Zeynep², Wei Li³, Zhiwen Zhu¹ zhiwenzhu@126.com, Guangshuo Ou¹

Source: Proceedings of the National Academy of Sciences of the United States of America. 8/23/2022, Vol. 119 Issue 34, p1-8. 13p.

Subject Terms: *TUBULINS, *CELL motility, *LOADING & unloading, *MOLECULAR motor proteins, *PHOSPHORYLATION