Safety, pharmacokinetics, and antiviral efficacy of the novel capsid assembly modulator GST-HG141 in patients with chronic hepatitis B: a phase 1 trial with a randomized, placebo-controlled design

Authors: Min Wu, Jiajia Mai, Hong Zhang, George Zhang, John Mao, Yanan Tang, Wenhao Yan, Wenqiang Wu, Jinlin Hou, Xieer Liang, Zhihong Liu, Yanhua Ding, Junqi Niu

Source: Virology Journal, Vol 21, Iss 1, Pp 1-9 (2024)

Subject Terms: Antiviral therapy, Hepatitis B, Pharmacokinetics, Tolerability, Capsid assembly modulator, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/5bc7956a24714399bc46609ddbf4cb5e

Chromatin loops gather targets of upstream regulators together for efficient gene transcription regulation during vernalization in wheat

Authors: Yanyan Liu, Xintong Xu, Chao He, Liujie Jin, Ziru Zhou, Jie Gao, Minrong Guo, Xin Wang, Chuanye Chen, Mohammed H. Ayaad, Xingwang Li, Wenhao Yan

Source: Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)

Subject Terms: Wheat, Vernalization, Epigenome, Gene transcription regulation, Chromatin interaction, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/b3093fed5c994e96b23128b200030d53

Dynamic atlas of histone modifications and gene regulatory networks in endosperm of bread wheat

Authors: Chao He, Siteng Bi, Yuqi Li, Chengxiang Song, Heping Zhang, Xintong Xu, Qiang Li, Sulaiman Saeed, Wei Chen, Chunjie Zhao, Caixia Lan, Handong Su, Hailiang Mao, Wenhao Yan

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7603d96779464ae9a701a408d5adf71a

Social inequity of park accessibility in Taiyuan: highlighting the unfair layout of parks in second-tier cities of China and the relative role of contributors

Authors: Jing He, Fu Ren, Jiaxin Dong, Huihui Zhang, Wenhao Yan, Jiping Liu

Source: Geo-spatial Information Science, Vol 27, Iss 4, Pp 1118-1140 (2024)

Subject Terms: Parks, social inequity, spatial equality, accessibility, social vulnerable groups, Taiyuan, Mathematical geography. Cartography, GA1-1776, Geodesy, QB275-343

File Description: electronic resource

Relation: https://doaj.org/toc/1009-5020; https://doaj.org/toc/1993-5153

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Comprehensive integration of single-cell transcriptomic data illuminates the regulatory network architecture of plant cell fate specification

Authors: Shanni Cao, Xue Zhao, Zhuojin Li, Ranran Yu, Yuqi Li, Xinkai Zhou, Wenhao Yan, Dijun Chen, Chao He

Source: Plant Diversity, Vol 46, Iss 3, Pp 372-385 (2024)

Subject Terms: Arabidopsis, Single cell transcriptome, Gene regulatory network, Data integration, Plant cell atlas, Biology (General), QH301-705.5, Botany, QK1-989

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468265924000477; https://doaj.org/toc/2468-2659

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Epigenetic control on transcription of vernalization genes and whole-genome gene expression profile induced by vernalization in common wheat

Authors: Yunzhen Li, Liujie Jin, Xinyu Liu, Chao He, Siteng Bi, Sulaiman Saeed, Wenhao Yan

Source: Plant Diversity, Vol 46, Iss 3, Pp 386-394 (2024)

Subject Terms: Wheat, Vernalization, VRN1, Histone modification, Regulate network, Biology (General), QH301-705.5, Botany, QK1-989

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Relation: http://www.sciencedirect.com/science/article/pii/S2468265924000192; https://doaj.org/toc/2468-2659

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The Progress in Treatment of β-Thalassemia and Research on Animal Models of the Disease

Authors: Shumeng Zhang, Zexia Dong, Wenhao Yan, Wenjing Wang, Yangli Pei, Zheng Feng

Source: Applied Sciences, Vol 15, Iss 3, p 1661 (2025)

Subject Terms: β-thalassemia, animal models, research progress, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

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Relation: https://www.mdpi.com/2076-3417/15/3/1661; https://doaj.org/toc/2076-3417

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RBFNN-PSO Intelligent Synchronisation Method for Sprott B Chaotic Systems with External Noise and Its Application in an Image Encryption System

Authors: Yanpeng Zhang, Jian Zeng, Wenhao Yan, Qun Ding

Source: Entropy, Vol 26, Iss 10, p 855 (2024)

Subject Terms: Sprott B system, RBFNN-PSO synchronisation method, Zigzag disruption method, Science, Astrophysics, QB460-466, Physics, QC1-999

File Description: electronic resource

Relation: https://www.mdpi.com/1099-4300/26/10/855; https://doaj.org/toc/1099-4300

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Efficacy and safety of GST-HG171 in adult patients with mild to moderate COVID-19: a randomised, double-blind, placebo-controlled phase 2/3 trialResearch in context

Authors: Hongzhou Lu, George Zhang, John Mao, Xiaochun Chen, Yangqing Zhan, Ling Lin, Tianxiang Zhang, Yanan Tang, Feng Lin, Feiyue Zhu, Yuanlong Lin, Yiming Zeng, Kaiyu Zhang, Wenfang Yuan, Zhenyu Liang, Ruilin Sun, Liya Huo, Peng Hu, Yihua Lin, Xibin Zhuang, Zhaohui Wei, Xia Chen, Wenhao Yan, Xiuping Yan, Lisa Mu, Zhuhua Lin, Xinyu Tu, Hongshan Tan, Fuhu Huang, Zhiqiang Hu, Hongming Li, Guoping Li, Haijun Fu, Zifeng Yang, Xinwen Chen, Fu-Sheng Wang, Nanshan Zhong

Source: EClinicalMedicine, Vol 71, Iss , Pp 102582- (2024)

Subject Terms: Anti SARS-CoV-2 drug, COVID-19, RCT, 3CL protease, XBB variants, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537024001615; https://doaj.org/toc/2589-5370

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Dissecting the molecular basis of spike traits by integrating gene regulatory networks and genetic variation in wheat

Authors: Guo Ai, Chao He, Siteng Bi, Ziru Zhou, Ankui Liu, Xin Hu, Yanyan Liu, Liujie Jin, JiaCheng Zhou, Heping Zhang, Dengxiang Du, Hao Chen, Xin Gong, Sulaiman Saeed, Handong Su, Caixia Lan, Wei Chen, Qiang Li, Hailiang Mao, Lin Li, Hao Liu, Dijun Chen, Kerstin Kaufmann, Khaled F. Alazab, Wenhao Yan

Source: Plant Communications, Vol 5, Iss 5, Pp 100879- (2024)

Subject Terms: bread wheat, spike traits, genetic variation, protein–protein interaction, gene regulatory network, Botany, QK1-989

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590346224001214; https://doaj.org/toc/2590-3462

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Optimised Design and Simulation Analysis of a Double-Row Pneumatic Injection Seeding Device

Authors: Qi Niu, Wei Yu, Wenhao Yan, Helong Zhang, Lihong Wang, Chengsong Li, Chunlei Wang

Source: Agriculture, Vol 14, Iss 8, p 1376 (2024)

Subject Terms: stem mustard, pneumatic seeding, non-tillage sowing, fluid simulation, Agriculture (General), S1-972

File Description: electronic resource

Relation: https://www.mdpi.com/2077-0472/14/8/1376; https://doaj.org/toc/2077-0472

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Asymmetric gene expression and cell-type-specific regulatory networks in the root of bread wheat revealed by single-cell multiomics analysis

Authors: Lihua Zhang, Chao He, Yuting Lai, Yating Wang, Lu Kang, Ankui Liu, Caixia Lan, Handong Su, Yuwen Gao, Zeqing Li, Fang Yang, Qiang Li, Hailiang Mao, Dijun Chen, Wei Chen, Kerstin Kaufmann, Wenhao Yan

Source: Genome Biology, Vol 24, Iss 1, Pp 1-25 (2023)

Subject Terms: Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/4a11ff98ca84455eaed988c277cd0c69

A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review

Authors: Tamang Sapana, Wei Li, Fengyan Tian, Wenhao Yan, Binghua Dou, Shuang Hua, Zhihong Zhuo

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: anti GAD65 antibody, T1DM (type 1 diabetes mellitus), autoimmune thyroiditis, pediatric, autoimmune polyendocrine syndrome (APS type 2), abnormal (behavior), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1274672/full; https://doaj.org/toc/1664-3224

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Generalized 2D polynomial chaotic map and its application in information transmission

Authors: Wenhao YAN, Zijing JIANG, Xin HUANG, Shujuan ZHU, Qun DING

Source: Tongxin xuebao, Vol 43, Pp 80-89 (2022)

Subject Terms: Lyapunov exponent, dynamic degradation, chaotic map, secure communication, Telecommunication, TK5101-6720

File Description: electronic resource

Relation: https://doaj.org/toc/1000-436X

Access URL: https://doaj.org/article/61ad6e9fcc0a47d38307c6d77d593c30

A 3D gene expression atlas of the floral meristem based on spatial reconstruction of single nucleus RNA sequencing data

Authors: Manuel Neumann, Xiaocai Xu, Cezary Smaczniak, Julia Schumacher, Wenhao Yan, Nils Blüthgen, Thomas Greb, Henrik Jönsson, Jan Traas, Kerstin Kaufmann, Jose M. Muino

Source: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)

Subject Terms: Science

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Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/1a93de9b9c1d4973859d506920907714

Mapping open chromatin by ATAC-seq in bread wheat

Authors: Xin Wang, Chuanye Chen, Chao He, Dijun Chen, Wenhao Yan

Source: Frontiers in Plant Science, Vol 13 (2022)

Subject Terms: ATAC-seq, chromatin accessibility, reproducible peak, data evaluation, regulatory elements, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpls.2022.1074873/full; https://doaj.org/toc/1664-462X

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Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay

Authors: Aijie Cai, Wenhao Yan, Xiaojun Zeng, Samson B. Zacate, Tzu-Hsuan Chao, Jeanette A. Krause, Mu-Jeng Cheng, Wei Liu

Source: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2631e74ef56744c9b19881e8824bf0a4

Plant growth‐promoting rhizobacteria isolation from rhizosphere of submerged macrophytes and their growth‐promoting effect on Vallisneria natans under high sediment organic matter load

Authors: Chuan Wang, Huihui Wang, Yahua Li, Qianzheng Li, Wenhao Yan, Yi Zhang, Zhenbin Wu, Qiaohong Zhou

Source: Microbial Biotechnology, Vol 14, Iss 2, Pp 726-736 (2021)

Subject Terms: Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/1751-7915

Access URL: https://doaj.org/article/03393b272ea14642af6cc2207a526aef

Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease

Authors: He Lin, Houlei Teng, Wei Wu, Yong Li, Guangfu Lv, Xiaowei Huang, Wenhao Yan, Zhe Lin

Source: BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-12 (2020)

Subject Terms: Mangiferin calcium salt, Diabetes, NAFLD, Pharmacokinetics, Metabolomics, Bioavailability, Therapeutics. Pharmacology, RM1-950, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40360-020-00438-x; https://doaj.org/toc/2050-6511

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Adaptive Neural Network Synchronization Control for Uncertain Fractional-Order Time-Delay Chaotic Systems

Authors: Wenhao Yan, Zijing Jiang, Xin Huang, Qun Ding

Source: Fractal and Fractional, Vol 7, Iss 4, p 288 (2023)

Subject Terms: radial basis neural network, Lyapunov stability theory, fractional-order time-delay chaotic system, Thermodynamics, QC310.15-319, Mathematics, QA1-939, Analysis, QA299.6-433

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Relation: https://www.mdpi.com/2504-3110/7/4/288; https://doaj.org/toc/2504-3110

Access URL: https://doaj.org/article/c0229204471842068c5ae2695e8e001c