CKD-Associated Pruritus and Clinical Outcomes in Nondialysis CKD

Authors: Lopes, Antonio, Pecoits-Filho, Roberto, Combe, Christian, Jacquelinet, Christian, Massy, Ziad, Stengel, Benedicte, Duttlinger, Johannes, Fliser, Danilo, Lonnemann, Gerhard, Reichel, Helmut, Wada, Takashi, Yamagata, Kunihiro, Pisoni, Ron, Robinson, Bruce, Calice da Silva, Viviane, Sesso, Ricardo, Speyer, Elodie, Asahi, Koichi, Hoshino, Junichi, Narita, Ichiei, Perlman, Rachel, Port, Friedrich, Sukul, Nidhi, Wong, Michelle, Young, Eric, Zee, Jarcy, Scherer, Jennifer S., Tu, Charlotte, Pisoni, Ronald L., Lopes, Antonio A., Wen, Warren, Menzaghi, Frederique, Cirulli, Joshua, Alencar de Pinho, Natalia, Karaboyas, Angelo

Source: In Kidney Medicine January 2024 6(1)

The Burden of Pruritus Associated With CKD: A Mixed Methods Analysis Among Patients Undergoing Dialysis

Authors: Menzaghi, Frédérique, Vernon, Margaret K., Mattera, Maria, Cirulli, Joshua, Wen, Warren, Spencer, Robert H., Munera, Catherine

Source: In Kidney Medicine September 2023 5(9)

Safety and Effectiveness of Difelikefalin in Patients With Moderate-to-Severe Pruritus Undergoing Hemodialysis: An Open-Label, Multicenter Study

Authors: Weiner, Daniel E., Vervloet, Marc G., Walpen, Sebastian, Schaufler, Thilo, Munera, Catherine, Menzaghi, Frédérique, Wen, Warren, Bhaduri, Sarbani, Germain, Michael J.

Source: In Kidney Medicine October 2022 4(10)

Safety and Tolerability of Difelikefalin for the Treatment of Moderate to Severe Pruritus in Hemodialysis Patients: Pooled Analysis From the Phase 3 Clinical Trial Program

Authors: Fishbane, Steven, Wen, Warren, Munera, Catherine, Lin, Rong, Bagal, Sukirti, McCafferty, Kieran, Menzaghi, Frédérique, Goncalves, Joana

Source: In Kidney Medicine August 2022 4(8)

Efficacy of Difelikefalin for the Treatment of Moderate to Severe Pruritus in Hemodialysis Patients: Pooled Analysis of KALM-1 and KALM-2 Phase 3 Studies

Authors: Topf, Joel, Wooldridge, Thomas, McCafferty, Kieran, Schömig, Michael, Csiky, Botond, Zwiech, Rafal, Wen, Warren, Bhaduri, Sarbani, Munera, Catherine, Lin, Rong, Jebara, Alia, Cirulli, Joshua, Menzaghi, Frédérique

Source: In Kidney Medicine August 2022 4(8)

Self-reported Pruritus and Clinical, Dialysis-Related, and Patient-Reported Outcomes in Hemodialysis Patients

Authors: Sukul, Nidhi, Karaboyas, Angelo, Csomor, Philipp A., Schaufler, Thilo, Wen, Warren, Menzaghi, Frédérique, Rayner, Hugh C., Hasegawa, Takeshi, Al Salmi, Issa, Al-Ghamdi, Saeed M.G., Guebre-Egziabher, Fitsum, Ureña-Torres, Pablo-Antonio, Pisoni, Ronald L.

Source: In Kidney Medicine January-February 2021 3(1):42-53

Chronic kidney disease–associated pruritus and quality of life with difelikefalin treatment: a post hoc analysis of phase 3 data using the Skindex-10 questionnaire.

Authors: Ständer, Sonja, Fishbane, Steven, Schaufler, Thilo, Ruessmann, Despina, Morin, Isabelle, Menzaghi, Frédérique, Wen, Warren, Kalantar-Zadeh, Kamyar

Source: Clinical Kidney Journal; Oct2024, Vol. 17 Issue 10, p1-12, 12p

Subject Terms: CLINICAL trials, CHRONIC kidney failure, SOCIAL skills, QUALITY of life, HEMODIALYSIS patients, ITCHING

Difelikefalin improves itch-related sleep disruption in patients undergoing haemodialysis.

Authors: Weiner, Daniel E, Schaufler, Thilo, McCafferty, Kieran, Kalantar-Zadeh, Kamyar, Germain, Michael, Ruessmann, Despina, Morin, Isabelle, Menzaghi, Frédérique, Wen, Warren, Ständer, Sonja

Source: Nephrology Dialysis Transplantation; Jul2024, Vol. 39 Issue 7, p1125-1137, 13p

Subject Terms: SLEEP interruptions, SLEEP quality, HEMODIALYSIS patients, RANK correlation (Statistics), QUALITY of life

MO467: Time to Improvement of Itch Intensity in Patients With Chronic Kidney Disease-Associated Pruritus Treated With Difelikefalin

Authors: Csiky, Botond, Walpen, Sebastian, Schaufler, Thilo, Morin, Isabelle, Wen, Warren, Menzaghi, Frederique

Source: Nephrology dialysis transplantation. 37(Supplement 3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152545018.0x000001&indx=1&recIds=ETOCvdc_100152545018.0x000001

MO424: Relationship Between Itch Intensity and Patient-Reported Disease Improvement in Patients With Chronic Kidney Disease-Associated Pruritus Treated With Difelikefalin

Authors: Mccafferty, Kieran, Walpen, Sebastian, Schaufler, Thilo, Morin, Isabelle, Menzaghi, Frederique, Wen, Warren, Fishbane, Steven

Source: Nephrology dialysis transplantation. 37(Supplement 3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152544529.0x000001&indx=1&recIds=ETOCvdc_100152544529.0x000001

Long-term effectiveness and safety of once-daily, single-entity, extended-release hydrocodone in patients of ≥75 years of age with moderate to severe nonmalignant and nonneuropathic pain

Authors: Broglio, Kathleen, Pergolizzi, Joseph, Kowalski, Maribeth, Lynch, Shau Yu, He, Ellie, Wen, Warren

Source: In Geriatric Nursing January-February 2017 38(1):39-47

Pharmacokinetic Profile and Sustained 24-hour Analgesia of a Once-daily Hydrocodone Bitartrate Extended-release Tablet with Abuse-deterrent Properties

Authors: Kapil, Ram P., Cipriano, Alessandra, Wen, Warren, Yu Lynch, Shau, He, Ellie, Colucci, Salvatore V., Harris, Stephen C.

Source: In Clinical Therapeutics February 2016 38(2):302-314

Difelikefalin in Black/African American Hemodialysis Patients with Moderate-to-Severe Pruritus: Post hoc Analysis of KALM-1 and KALM-2.

Authors: Fishbane, Steven, Clegg, Deborah J., Lerma, Edgar V., Rastogi, Anjay, Budden, Jeffrey, Morin, Isabelle, Wen, Warren, Menzaghi, Frédérique, Topf, Joel

Source: American Journal of Nephrology; 2024, Vol. 55 Issue 3, p329-333, 5p

Subject Terms: HEMODIALYSIS patients, AFRICAN Americans, ITCHING, KIDNEY failure

Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations

Authors: Edwards, Robert R., Dworkin, Robert H., Turk, Dennis C., Angst, Martin S., Dionne, Raymond, Freeman, Roy, Hansson, Per, Haroutounian, Simon, Arendt-Nielsen, Lars, Attal, Nadine, Baron, Ralf, Brell, Joanna, Bujanover, Shay, Burke, Laurie B., Carr, Daniel, Chappell, Amy S., Cowan, Penney, Etropolski, Mila, Fillingim, Roger B., Gewandter, Jennifer S., Katz, Nathaniel P., Kopecky, Ernest A., Markman, John D., Nomikos, George, Porter, Linda, Rappaport, Bob A., Rice, Andrew S.C., Scavone, Joseph M., Scholz, Joachim, Simon, Lee S., Smith, Shannon M., Tobias, Jeffrey, Tockarshewsky, Tina, Veasley, Christine, Versavel, Mark, Wasan, Ajay D., Wen, Warren, Yarnitsky, David

Source: Pain. 157(9):1851-1871

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174968429.0x000001&indx=1&recIds=ETOCvdc_100174968429.0x000001

A Randomized, Placebo-Controlled Study of the Impact of the 7-Day Buprenorphine Transdermal System on Health-Related Quality of Life in Opioid-Naïve Patients With Moderate-to-Severe Chronic Low Back Pain

Authors: Yarlas, Aaron, Miller, Kate, Wen, Warren, Dain, Bradley, Lynch, Shau Yu, Pergolizzi, Joseph V., Raffa, Robert B., Ripa, Steven R.

Source: In Journal of Pain January 2013 14(1):14-23

A multicenter, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of single-entity, once-daily hydrocodone tablets in patients with uncontrolled moderate to severe chronic low back pain

Authors: Wen, Warren, Sitar, Steve, Lynch, Shau Yu, He, Ellie, Ripa, Steven R

Source: Expert opinion on pharmacotherapy. 16(11):1593-1606

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106467119.0x000001&indx=1&recIds=ETOCvdc_100106467119.0x000001

Buprenorphine transdermal system compared with placebo reduces interference in functioning for chronic low back pain

Authors: Yarlas, Aaron, Miller, Kate, Wen, Warren, Lynch, Shau Yu, Munera, Catherine, Pergolizzi, Joseph V., Raffa, Robert, Ripa, Steven R.

Source: Postgraduate medicine. 127(1):38-45

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106905790.0x000001&indx=1&recIds=ETOCvdc_100106905790.0x000001

Efficacy and safety of once-daily, extended-release hydrocodone in individuals previously receiving hydrocodone/acetaminophen combination therapy for chronic pain

Authors: Bartoli, Adrian, Michna, Edward, He, Ellie, Wen, Warren

Source: Postgraduate medicine. 127(1):5-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106905896.0x000001&indx=1&recIds=ETOCvdc_100106905896.0x000001

Pain intensity and interference with functioning and well-being in subgroups of patients with chronic pain treated with once-daily hydrocodone tablets

Authors: Bartoli, Adrian, Michna, Edward, He, Ellie, Wen, Warren

Source: Journal of opioid management. 11(6):519-533

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN604483462&indx=1&recIds=ETOCRN604483462

12-Month safety and effectiveness of once-daily hydrocodone tablets formulated with abuse-deterrent properties in patients with moderate to severe chronic pain

Authors: Wen, Warren, Taber, Louise, Lynch, Shau Yu, He, Ellie, Ripa, Steven

Source: Journal of opioid management. 11(4):339-356

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN603018760&indx=1&recIds=ETOCRN603018760