H19 promotes polarization and alternative splicing in tumor-associated macrophages, facilitating pancreatic cancer progression

Authors: Liu, Pengyi ^{a, b, c, ⁎, 1}, Gao, Xia ^{d, 1}, Yu, Zhengwei ^{e, 1}, Liu, Yang ^{a, b, c}, Liu, Yihao ^{a, b, c}, Lin, Jiayu ^{a, b, c}, Cao, Yizhi ^{a, b, c}, Zhai, Shuyu ^{a, b, c}, Li, Jingwei ^{a, b, c}, Huang, Yishu ^{a, b, c}, Zou, Siyi ^{a, b, c}, Wen, Chenlei ^{a, b, c}, Fu, Da ^{a, b, c, ⁎⁎}, Lin, Jiewei ^{f, ⁎⁎⁎}, Shen, Baiyong ^{a, b, c, ⁎⁎⁎⁎}

Source: In Cancer Letters 28 February 2025 611

Irreversible electroporation combined with PD-L1/IL-6 dual blockade promotes anti-tumor immunity via cDC2/CD4+T cell axis in MHC-I deficient pancreatic cancer

Authors: Wu, Zhuozhuo ^{a, 1}, Shan, Qungang ^{a, 1}, Jiang, Yuyue ^{a, 1}, Huang, Wei ^{a, 1}, Wang, Ziyin ^a, Zhuang, Yaping ^b, Liu, Jingjing ^a, Li, Tiankuan ^a, Yang, Ziyu ^c, Li, Chaojie ^{a, g}, Wei, Tao ^d, Wen, Chenlei ^e, Cui, Wenguo ^b, Qiu, Zilong ^f, Liu, Xiaoyu ^{a, c, ⁎}, Wang, Zhongmin ^{a, c, g, ⁎⁎}

Source: In Cancer Letters 1 May 2025 617

CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches

Authors: Tang, Jiajia, Zheng, Quan, Wang, Qi, Zhao, Yaru, Ananthanarayanan, Preeta, Reina, Chiara, Šabanović, Berina, Jiang, Ke, Yang, Ming-Hsin, Meny, Clara Csilla, Wang, Huimin, Agerbaek, Mette Ø., Clausen, Thomas Mandel, Gustavsson, Tobias, Wen, Chenlei, Borghi, Felice, Mellano, Alfredo, Fenocchio, Elisabetta, Gregorc, Vanesa, Sapino, Anna, Theander, Thor G., Fu, Da, Aicher, Alexandra, Salanti, Ali, Shen, Baiyong, Heeschen, Christopher

Source: In Cell Reports Medicine 17 September 2024 5(9)

Driver mutation subtypes involve with differentiated immunophenotypes influencing pancreatic cancer outcomes

Authors: Zou, Siyi, Zhang, Lei, Jiang, Cen, Li, Fanlu, Yang, Ying, Deng, Xiaxing, Zhang, Jiao, Chen, Hao, Jiang, Lingxi, Cheng, Xueyan, Deng, Lisha, Lin, Lin, Shen, Baiyong, Wen, Chenlei, Zhan, Qian

Source: In Cancer Letters 1 September 2024 599

Association between age at diabetes onset or diabetes duration and subsequent risk of pancreatic cancer: results from a longitudinal cohort and mendelian randomization study

Authors: Shen, Baiyong, Li, Yanyun, Sheng, Chang-Sheng, Liu, Lili, Hou, Tianzhichao, Xia, Nan, Sun, Siming, Miao, Ya, Pang, Yi, Gu, Kai, Lu, Xiongxiong, Wen, Chenlei, Cheng, Yi, Yang, Yulin, Wang, Dan, Zhu, Yijie, Cheng, Minna, Harris, Katie, Bloomgarden, Zachary T., Tian, Jingyan, Chalmers, John, Shi, Yan

Source: In The Lancet Regional Health - Western Pacific January 2023 30

Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort

Authors: Zhan, Qian, Wen, Chenlei, Zhao, Yi, Fang, Lu, Jin, Yangbing, Zhang, Zehui, Zou, Siyi, Li, Fanlu, Yang, Ying, Wu, Lijia, Jin, Jiabin, Lu, Xiongxiong, Xie, Junjie, Cheng, Dongfeng, Xu, Zhiwei, Zhang, Jun, Wang, Jiancheng, Deng, XiaXing, Chen, Hao, Peng, Chenghong, Li, Hongwei, Zhang, Henghui, Fang, Hai, Wang, Chaofu, Shen, Baiyong

Source: In eBioMedicine December 2021 74

Gasdermin C promotes Stemness and Immune Evasion in Pancreatic Cancer via Pyroptosis‐Independent Mechanism.

Authors: Wu, Renfei^1,2, Li, Jingwei^1,2,3,4, Aicher, Alexandra^5,6, Jiang, Ke^1,2, Tondi, Serena⁷, Dong, Shuang^1,2, Zheng, Quan^1,2, Tang, Siqi⁸, Chen, Minchun^1,2, Guo, Zhenyang^1,2, Šabanović, Berina⁷, Ananthanarayanan, Preeta⁷, Jiang, Lingxi^2,3,4, Sapino, Anna⁹, Wen, Chenlei^2,3,4, Fu, Da^2,3,4, Shen, Baiyong^2,3,4, Heeschen, Christopher^1,2,7, christopher.heeschen@icloud.com

Source: Advanced Science; 11/13/2024, Vol. 11 Issue 42, p1-24, 24p

Internally and externally to inherit the history——the 3rd Oriental Congress of General Surgery

Authors: WEN Chenlei, SHEN Baiyong

Source: Waike lilun yu shijian, Vol 27, Iss 06, Pp 569-570 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Surgery, RD1-811

File Description: electronic resource

Relation: https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1675064424899-83806300.pdf; https://doaj.org/toc/1007-9610

Access URL: https://doaj.org/article/fef0e92e4d4e4e618090a6ac85f591bc

Tumor copy number instability is a significant predictor for late recurrence after radical surgery of pancreatic ductal adenocarcinoma

Authors: Wen, Chenlei, Deng, XiaXing, Ren, Dandan, Song, Xue, Chen, Hao, Wang, Jiancheng, Jin, Jiabin, Cheng, Dongfeng, Xu, Zhiwei, Zhang, Jun, Xie, Junjie, Qi, Wenjing, Gu, Jiangning, Peng, Chenghong, Chen, Dan, Chen, Shi, Shen, Baiyong, Zhan, Qian

Source: Cancer medicine. 9(20):7626-7636

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108627783.0x000001&indx=1&recIds=ETOCvdc_100108627783.0x000001

Melittin inhibits tumor growth and decreases resistance to gemcitabine by downregulating cholesterol pathway gene CLU in pancreatic ductal adenocarcinoma

Authors: Wang, Xinjing, Xie, Jing, Lu, Xiongxiong, Li, Hongzhe, Wen, Chenlei, Huo, Zhen, Xie, Junjie, Shi, Minmin, Tang, Xiaomei, Chen, Hao, Peng, Chenghong, Fang, Yuan, Deng, Xiaxing, Shen, Baiyong

Source: In Cancer Letters 28 July 2017 399:1-9

Melittin-induced long non-coding RNA NONHSAT105177 inhibits proliferation and migration of pancreatic ductal adenocarcinoma

Authors: Wang, Xinjing, Li, Hongzhe, Lu, Xiongxiong, Wen, Chenlei, Huo, Zhen, Shi, Minmin, Tang, Xiaomei, Chen, Hao, Peng, Chenghong, Fang, Yuan, Deng, Xiaxing, Shen, Baiyong

Source: Cell death and disease. 9(10):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182761203.0x000001&indx=1&recIds=ETOCvdc_100182761203.0x000001

BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.

Authors: Cao, Yizhi^1,2,3,4,5, Wang, Xuelong^1,2,3,4,5, Liu, Yang^1,2,3,4,5, Liu, Pengyi^1,2,3,4,5, Qin, Jiejie^1,2,3,4,5, Zhu, Youwei^1,2,3,4,5, Zhai, Shuyu^1,2,3,4,5, Jiang, Yongsheng^1,2,3,4,5, Liu, Yihao^1,2,3,4,5, Han, Lijie^1,2,3,4,5, Luo, Jiaxin^1,2,3,4,5, Zhang, Ronghao^1,2,3,4,5, Shi, Minmin^1,2,3,4,5, Wang, Liwen^1,2,3,4,5, Tang, Xiaomei^1,2,3,4,5, Xue, Meilin^1,2,3,4,5, Liu, Jia^1,2,3,4,5, Wang, Weishen^1,2,3,4,5, Wen, Chenlei^1,2,3,4,5, Deng, Xiaxing^1,2,3,4,5

Source: Advanced Science; 2/16/2024, Vol. 11 Issue 7, p1-18, 18p

Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer

Authors: Li, Hongzhe, Wang, Xinjing, Wen, Chenlei, Huo, Zhen, Wang, Weishen, Zhan, Qian, Cheng, Dongfeng, Chen, Hao, Deng, Xiaxing, Peng, Chenghong, Shen, Baiyong

Source: Molecular cancer. 16(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147776104.0x000001&indx=1&recIds=ETOCvdc_100147776104.0x000001

MiR-216a decreases MALAT1 expression, induces G2/M arrest and apoptosis in pancreatic cancer cells

Authors: Zhang, Yajing, Tang, Xiaomei, Shi, Minmin, Wen, Chenlei, Shen, Baiyong

Source: Biochemical and biophysical research communications. 483(2):816-822

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100047771995.0x000001&indx=1&recIds=ETOCvdc_100047771995.0x000001

Protocol for the creation and utilization of 3D pancreatic cancer models from circulating tumor cells

Authors: Tang, Jiajia ^{1, 2, 16, 17, ∗}, Zheng, Quan ^{1, 2, 16}, Wang, Qi ^{1, 2, 16}, Zhao, Yaru ^{1, 2}, Ananthanarayanan, Preeta ³, Reina, Chiara ³, Šabanović, Berina ³, Jiang, Ke ^{1, 2}, Yang, Ming-Hsin ⁴, Meny, Clara Csilla ⁵, Wang, Huimin ^{1, 2}, Agerbaek, Mette Ø. ^{6, 7}, Clausen, Thomas Mandel ⁶, Gustavsson, Tobias ^{6, 8}, Wen, Chenlei ^{9, 10, 11}, Borghi, Felice ¹², Mellano, Alfredo ¹², Fenocchio, Elisabetta ¹³, Gregorc, Vanesa ¹³, Sapino, Anna ¹⁴, Theander, Thor G. ⁶, Fu, Da ^{9, 10, 11}, Aicher, Alexandra ¹⁵, Salanti, Ali ⁶, Shen, Baiyong ^{9, 10, 11}, Heeschen, Christopher ^{1, 2, 3, 18, ∗∗}

Source: In STAR Protocols 21 March 2025 6(1)

Combination therapy of KRAS G12V mRNA vaccine and pembrolizumab: clinical benefit in patients with advanced solid tumors

Authors: Wang, Xinjing, Wang, Wei, Zou, Siyi, Xu, Zhiwei, Cao, Dan, Zhang, Shuai, Wei, Minzhi, Zhan, Qian, Wen, Chenlei, Li, Fanlu, Chen, Hao, Fu, Da, Jiang, Lingxi, Zhao, Ming, Shen, Baiyong

Source: Cell Research; 20240101, Issue: Preprints p1-4, 4p

Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment

Authors: Wang, Liwen, Liu, Yihao, Dai, Yuting, Tang, Xiaomei, Yin, Tong, Wang, Chaofu, Wang, Ting, Dong, Lei, Shi, Minmin, Qin, Jiejie, Xue, Meilin, Cao, Yizhi, Liu, Jia, Liu, Pengyi, Huang, Jinyan, Wen, Chenlei, Zhang, Jun, Xu, Zhiwei, Bai, Fan, Deng, Xiaxing, Peng, Chenghong, Chen, Hao, Jiang, Lingxi, Chen, Saijuan, Shen, Baiyong

Source: Gut; 2023, Vol. 72 Issue: 5 p958-971, 14p

Molecular subtypes of pancreatic adenocarcinoma stratified based on copy number variation profile.

Authors: Zhan, Qian, Wen, Chenlei, Yi, Zhao, Zhang, Henghui, Shen, Baiyong

Source: Journal of clinical oncology. 39(15 suppl):e16232-e16232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173201198.0x000001&indx=1&recIds=ETOCvdc_100173201198.0x000001

Postoperative hyperprogression disease of pancreatic ductal adenocarcinoma after curative resection: a retrospective cohort study.

Authors: Zou, Siyi, Wang, Xinjing, Chen, Haoda, Lin, Jiewei, Wen, Chenlei, Zhan, Qian, Chen, Hao, Lu, Xiongxiong, Deng, Xiaxing, Shen, Baiyong

Source: BMC Cancer; 6/13/2022, Vol. 22 Issue 1, p1-14, 14p

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma.

Authors: Liu, Yihao, Shi, Minmin, He, Xingfeng, Cao, Yizhi, Liu, Pengyi, Li, Fanlu, Zou, Siyi, Wen, Chenlei, Zhan, Qian, Xu, Zhiwei, Wang, Jiancheng, Sun, Baofa, Shen, Baiyong

Source: Journal of Hematology & Oncology; 5/7/2022, Vol. 15 Issue 1, p1-18, 18p

Subject Terms: PANCREATIC duct, FLUORESCENCE in situ hybridization, MACROPHAGES, ADENOCARCINOMA, HISTONE acetylation