Exploring the thrombus niche: lessons learned and potential therapeutic opportunities

Authors: Weisel, John W. ^{1, ∗}, Litvinov, Rustem I. ¹

Source: In Blood January 2025

Structural and functional changes underlying activation of monocytes in heparin-induced thrombocytopenia

Authors: Andrianova, Izabella ^{1, 2, 3}, Hayes, Vincent ¹, Litvinov, Rustem I. ³, Nagaswami, Chandrasekaran ³, Arepally, Gowthami M. ⁴, Cines, Douglas B. ^{5, 6}, Poncz, Mortimer ^{1, 7}, Weisel, John W. ³, Rauova, Lubica ^{1, 7, ∗}

Source: In Journal of Thrombosis and Haemostasis January 2025

Rupture mechanics of blood clots: Influence of fibrin network structure on the rupture resistance

Authors: Ramanujam, Ranjini K. ^a, Maksudov, Farkhad ^b, Risman, Rebecca A. ^a, Litvinov, Rustem I. ^c, Weisel, John W. ^c, Bassani, John L. ^c, Barsegov, Valeri ^b, Purohit, Prashant K. ^c, Tutwiler, Valerie ^{a, ⁎}

Source: In Acta Biomaterialia December 2024 190:329-343

The differential formation and composition of leukocyte-platelet aggregates induced by various cellular stimulants

Authors: Peshkova, Alina D., Saliakhutdinova, Shakhnoza M., Sounbuli, Khetam, Selivanova, Yuliya A., Andrianova, Izabella A., Khabirova, Alina I., Litvinov, Rustem I., Weisel, John W.

Source: In Thrombosis Research September 2024 241

Time-dependent ultrastructural changes during venous thrombogenesis and thrombus resolution

Authors: Chernysh, Irina N., Mukhopadhyay, Subhradip, Johnson, Tierra A., Brooks, Jacob A., Sarkar, Rajabrata, Weisel, John W., Antalis, Toni M.

Source: In Journal of Thrombosis and Haemostasis June 2024 22(6):1675-1688

Composition of thrombi in zebrafish: similarities and distinctions with mammals

Authors: Griffin, Megan S., Dahlgren, Anna R., Nagaswami, Chandrasekaran, Litvinov, Rustem I., Keeler, Kevin, Madenjian, Charles, Fuentes, Ricardo, Fish, Richard J., Neerman-Arbez, Marguerite, Holinstat, Michael, Adili, Reheman, Weisel, John W., Shavit, Jordan A.

Source: In Journal of Thrombosis and Haemostasis April 2024 22(4):1056-1068

Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology

Authors: Kim, Oleg V., Litvinov, Rustem I., Gagne, Alyssa L., French, Deborah L., Brass, Lawrence F., Weisel, John W.

Source: In Blood 8 February 2024 143(6):548-560

Fracture toughness of fibrin gels as a function of protein volume fraction: Mechanical origins

Authors: Garyfallogiannis, Konstantinos, Ramanujam, Ranjini K., Litvinov, Rustem I., Yu, Tony, Nagaswami, Chandrasekaran, Bassani, John L., Weisel, John W., Purohit, Prashant K., Tutwiler, Valerie

Source: Acta biomaterialia. 159:49-62

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184386989.0x000001&indx=1&recIds=ETOCvdc_100184386989.0x000001

Role of red blood cells in clinically relevant bleeding tendencies and complications

Authors: Lassila, Riitta, Weisel, John W.

Source: In Journal of Thrombosis and Haemostasis November 2023 21(11):3024-3032

Activation of Piezo1 channels in compressed red blood cells augments platelet-driven contraction of blood clots

Authors: Evtugina, Natalia G., Peshkova, Alina D., Khabirova, Alina I., Andrianova, Izabella A., Abdullayeva, Shahnoza, Ayombil, Francis, Shepeliuk, Taisia, Grishchuk, Ekaterina L., Ataullakhanov, Fazoil I., Litvinov, Rustem I., Weisel, John W.

Source: In Journal of Thrombosis and Haemostasis September 2023 21(9):2418-2429

Blood clot contraction: Mechanisms, pathophysiology, and disease

Authors: Litvinov, Rustem I., Weisel, John W.

Source: In Research and Practice in Thrombosis and Haemostasis January 2023 7(1)

An Automated Approach for Fibrin Network Segmentation and Structure Identification in 3D Confocal Microscopy Images

Authors: Chen, Jianxu, Kim, Oleg V., Litvinov, Rustem I., Weisel, John W., Alber, Mark S., Chen, Danny Z.

Source: 2014 IEEE 27th International Symposium on Computer-Based Medical Systems Computer-Based Medical Systems (CBMS), 2014 IEEE 27th International Symposium on. :173-178 May, 2014

Relation: 2014 IEEE 27th International Symposium on Computer-Based Medical Systems (CBMS)

Incorporation of Fibrin, Platelets, and Red Blood Cells into a Coronary Thrombus in Time and Space

Authors: Maly, Martin, Riedel, Tomas, Stikarova, Jana, Suttnar, Jiri, Kotlin, Roman, Hajsl, Martin, Tousek, Petr, Kaufmanova, Jirina, Kucerka, Ondrej, Weisel, John, Dyr, Jan

Source: Thrombosis and haemostasis. 122(3):434-444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192116951.0x000001&indx=1&recIds=ETOCvdc_100192116951.0x000001

Nonmalignant portal vein thrombi in patients with cirrhosis consist of intimal fibrosis with or without a fibrin‐rich thrombus

Authors: Driever, Ellen G., von Meijenfeldt, Fien A., Adelmeijer, Jelle, de Haas, Robbert J., van den Heuvel, Marius C., Nagasami, Chandrasekaran, Weisel, John W., Fondevila, Constantino, Porte, Robert J., Blasi, Anabel, Heaton, Nigel, Gregory, Stephen, Kane, Pauline, Bernal, William, Zen, Yoh, Lisman, Ton

Source: Hepatology. 75(4):898-911

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191466033.0x000001&indx=1&recIds=ETOCvdc_100191466033.0x000001

Percutaneous delivery of self-propelling hemostatic powder for managing non-compressible abdominal hemorrhage: a proof-of-concept study in swine

Authors: Cau, Massimo F., Ali-Mohamad, Nabil, Baylis, James R., Zenova, Veronika, Khavari, Adele, Peng, Nuoya, McFadden, Andrew, Donnellan, Fergal, Owen, Daniel R., Schaeffer, David F., Nagaswami, Chandrasekaran, Litvinov, Rustem I., Weisel, John W., Rezende-Neto, Joao, Semple, Hugh A., Beckett, Andrew, Kastrup, Christian J.

Source: Injury. 53(5):1603-1609

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165394748.0x000001&indx=1&recIds=ETOCvdc_100165394748.0x000001

Effects of clot contraction on clot degradation: A mathematical and experimental approach

Authors: Risman, Rebecca A., Abdelhamid, Ahmed, Weisel, John W., Bannish, Brittany E., Tutwiler, Valerie

Source: In Biophysical Journal 6 September 2022 121(17):3271-3285

Biomechanical origins of inherent tension in fibrin networks

Authors: Spiewak, Russell, Gosselin, Andrew, Merinov, Danil, Litvinov, Rustem I., Weisel, John W., Tutwiler, Valerie, Purohit, Prashant K.

Source: In Journal of the Mechanical Behavior of Biomedical Materials September 2022 133

Molecular Mechanism of Transition from Catch-Bond to Slip-Bond in Fibrin

Authors: Litvinov, Rustem I., Kononova, Olga, Maksudov, Farkhad, Zhmurov, Artem, Marx, Kenneth A., Weisel, John W., Barsegov, Valeri

Subject Terms: Physics - Biological Physics

Access URL: http://arxiv.org/abs/1709.05727

Computational biomechanical modeling of fibrin networks and platelet-fiber network interactions

Authors: Pancaldi, Francesco ^∗, Kim, Oleg V., Weisel, John W., Alber, Mark, Xu, Zhiliang

Source: In Current Opinion in Biomedical Engineering June 2022 22

Extent of intravital contraction of arterial and venous thrombi and pulmonary emboli

Authors: Khismatullin, Rafael R., Abdullayeva, Shahnoza, Peshkova, Alina D., Sounbuli, Khetam, Evtugina, Natalia G., Litvinov, Rustem I., Weisel, John W. ^*

Source: In Blood Advances 22 March 2022 6(6):1708-1718