Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis

Authors: Diehl, Carina ^{1, 2, 20}, Soberón, Valeria ^{1, 2, 3, 4, 20}, Baygün, Seren ^{1, 2, 3, 20}, Chu, Yuanyuan ^{1, 4, 20}, Mandelbaum, Jonathan ⁵, Kraus, Laura ^{1, 2}, Engleitner, Thomas ^{2, 3, 6}, Rudelius, Martina ⁷, Fangazio, Marco ⁵, Daniel, Christoph ⁸, Bortoluzzi, Sabrina ^{1, 2}, Helmrath, Sabine ^{1, 2}, Singroul, Pankaj ^{1, 2}, Gölling, Vanessa ^{1, 2}, Osorio Barrios, Francisco ^{1, 2}, Seyhan, Gönül ^{1, 2}, Oßwald, Lena ^{1, 2, 9}, Kober-Hasslacher, Maike ^{1, 4}, Zeng, Theodor ^{1, 2}, Öllinger, Rupert ^{2, 3, 6}, Afzali, Ali M. ¹⁰, Korn, Thomas ¹⁰, Honarpisheh, Mohsen ¹¹, Lech, Maciej ¹¹, Ul Ain, Qurrat ¹², Pircher, Joachim ^{12, 13}, Imširović, Vanna ¹⁴, Jelenčić, Vedrana ¹⁴, Wensveen, Felix M. ¹⁴, Passerini, Verena ¹⁵, Bärthel, Stefanie ^{2, 3, 16}, Bhagat, Govind ¹⁷, Dominguez-Sola, David ¹⁸, Saur, Dieter ^{2, 3, 16}, Steiger, Katja ^{3, 19}, Rad, Roland ^{2, 3, 6}, Pasqualucci, Laura ^{5, 17}, Weigert, Oliver ^{3, 15}, Schmidt-Supprian, Marc ^{1, 2, 3, 4, 21, ∗}

Source: In Immunity 14 January 2025 58(1):124-142

The clinical and molecular taxonomy of t(14;18)-negative follicular lymphomas

Authors: Salaverria, Itziar, Weigert, Oliver, Quintanilla-Martinez, Leticia

Source: In Blood Advances 26 September 2023 7(18):5258-5271

Genomic profiling for clinical decision making in lymphoid neoplasms

Authors: de Leval, Laurence, Alizadeh, Ash A., Bergsagel, P. Leif, Campo, Elias, Davies, Andrew, Dogan, Ahmet, Fitzgibbon, Jude, Horwitz, Steven M., Melnick, Ari M., Morice, William G., Morin, Ryan D., Nadel, Bertrand, Pileri, Stefano A., Rosenquist, Richard, Rossi, Davide, Salaverria, Itziar, Steidl, Christian, Treon, Steven P., Zelenetz, Andrew D., Advani, Ranjana H., Allen, Carl E., Ansell, Stephen M., Chan, Wing C., Cook, James R., Cook, Lucy B., d'Amore, Francesco, Dirnhofer, Stefan, Dreyling, Martin, Dunleavy, Kieron, Feldman, Andrew L., Fend, Falko, Gaulard, Philippe, Ghia, Paolo, Gribben, John G., Hermine, Olivier, Hodson, Daniel J., Hsi, Eric D., Inghirami, Giorgio, Jaffe, Elaine S., Karube, Kennosuke, Kataoka, Keisuke, Klapper, Wolfram, Kim, Won Seog, King, Rebecca L., Ko, Young H., LaCasce, Ann S., Lenz, Georg, Martin-Subero, José I., Piris, Miguel A., Pittaluga, Stefania, Pasqualucci, Laura, Quintanilla-Martinez, Leticia, Rodig, Scott J., Rosenwald, Andreas, Salles, Gilles A., San-Miguel, Jesus, Savage, Kerry J., Sehn, Laurie H., Semenzato, Gianpietro, Staudt, Louis M., Swerdlow, Steven H., Tam, Constantine S., Trotman, Judith, Vose, Julie M., Weigert, Oliver, Wilson, Wyndham H., Winter, Jane N., Wu, Catherine J., Zinzani, Pier L., Zucca, Emanuele, Bagg, Adam, Scott, David W.

Source: Blood. 140(21):2193-2227

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183236714.0x000001&indx=1&recIds=ETOCvdc_100183236714.0x000001

T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals

Authors: Philipp, Nora, Kazerani, Maryam, Nicholls, Alyssa, Vick, Binje, Wulf, Jan, Straub, Tobias, Scheurer, Michaela, Muth, Amelie, Hänel, Gerulf, Nixdorf, Daniel, Sponheimer, Monika, Ohlmeyer, Malte, Lacher, Sonja M., Brauchle, Bettina, Marcinek, Anetta, Rohrbacher, Lisa, Leutbecher, Alexandra, Rejeski, Kai, Weigert, Oliver, von Bergwelt-Baildon, Michael, Theurich, Sebastian, Kischel, Roman, Jeremias, Irmela, Bücklein, Veit, Subklewe, Marion

Source: Blood. 140(10):1104-1118

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183236861.0x000001&indx=1&recIds=ETOCvdc_100183236861.0x000001

The molecular ontogeny of follicular lymphoma: gene mutations succeeding the BCL2 translocation define common precursor cells

Authors: Haebe, Sarah, Keay, William, Alig, Stefan, Mohr, Anne‐Wiebe, Martin, Larissa K., Heide, Michael, Secci, Ramona, Krebs, Stefan, Blum, Helmut, Moosmann, Andreas, Louissaint, Abner, Weinstock, David M., Thoene, Silvia, Bergwelt‐Baildon, Michael, Ruland, Jürgen, Bararia, Deepak, Weigert, Oliver

Source: British journal of haematology. 196(6):1381-1387

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144182565.0x000001&indx=1&recIds=ETOCvdc_100144182565.0x000001

Molekular zielgerichtete Therapien – brauchen wir überhaupt noch Chemotherapie? (German)

Alternate Title: Targeted therapies in the management of malignant lymphoma – is the end of conventional chemotherapy near? (English)

Authors: Hellmuth, Johannes C., Koch, Raphael, Weigert, Oliver

Source: Angewandte Nuklearmedizin; Mar2025, Vol. 48 Issue 1, p15-23, 9p

Adding checkpoint inhibitors to first-line chemotherapy for NUT carcinoma patients.

Authors: Haebe, Sarah, Schuebbe, Gesa, Jurmeister, Philipp, von Bergwelt-Baildon, Michael, Westphalen, C. Benedikt, Lauer, Ulrich M., Kunz, Wolfgang G., Subklewe, Marion, Weigert, Oliver

Source: NPJ Precision Oncology; 1/25/2025, Vol. 9 Issue 1, p1-6, 6p

Subject Terms: MEDICAL sciences, IMMUNE checkpoint inhibitors, CHEMORADIOTHERAPY, PROGRAMMED death-ligand 1, NASOPHARYNX

CAR-HEMATOTOX: a model for CAR T-cell–related hematologic toxicity in relapsed/refractory large B-cell lymphoma

Authors: Rejeski, Kai, Perez, Ariel, Sesques, Pierre, Hoster, Eva, Berger, Carolina, Jentzsch, Liv, Mougiakakos, Dimitrios, Frölich, Lisa, Ackermann, Josephine, Bücklein, Veit, Blumenberg, Viktoria, Schmidt, Christian, Jallades, Laurent, Fehse, Boris, Faul, Christoph, Karschnia, Philipp, Weigert, Oliver, Dreyling, Martin, Locke, Frederick L., von Bergwelt-Baildon, Michael, Mackensen, Andreas, Bethge, Wolfgang, Ayuk, Francis, Bachy, Emmanuel, Salles, Gilles, Jain, Michael D., Subklewe, Marion ^*

Source: In Blood 16 December 2021 138(24):2499-2513

Treatment dependence of prognostic gene expression signatures in de novo follicular lymphoma

Authors: Bolen, Christopher R., Mattiello, Federico, Herold, Michael, Hiddemann, Wolfgang, Huet, Sarah, Klapper, Wolfram, Marcus, Robert, Mir, Farheen, Salles, Gilles, Weigert, Oliver, Nielsen, Tina, Oestergaard, Mikkel Z., Venstrom, Jeffrey M.

Source: Blood. 137(19):2704-2707

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183251832.0x000001&indx=1&recIds=ETOCvdc_100183251832.0x000001

Schwere Candida-glabrata-Pankolitis und letale Aspergillus-fumigatus-Lungeninfektion vor dem Hintergrund einer Knochenmarkaplasie nach CD19-spezifischer CAR T-Zell-Therapie – ein Fallbericht

Authors: Rejeski, Kai, Kunz, Wolfgang G., Rudelius, Martina, Bücklein, Veit, Blumenberg, Viktoria, Schmidt, Christian, Karschnia, Philipp, Schöberl, Florian, Dimitriadis, Konstantin, von Baumgarten, Louisa, Stemmler, H. Joachim, Weigert, Oliver, Dreyling, Martin, von Bergwelt-Baildon, Michael, Subklewe, Marion

Source: Karger Kompass.Onkologie. 8(3):159-165

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129220181.0x000001&indx=1&recIds=ETOCvdc_100129220181.0x000001

Evaluating upfront high-dose consolidation after R-CHOP for follicular lymphoma by clinical and genetic risk models

Authors: Alig, Stefan, Jurinovic, Vindi, Shahrokh Esfahani, Mohammad, Haebe, Sarah, Passerini, Verena, Hellmuth, Johannes C., Gaitzsch, Erik, Keay, William, Tahiri, Natyra, Zoellner, Anna, Rosenwald, Andreas, Klapper, Wolfram, Stein, Harald, Feller, Alfred, Ott, German, Staiger, Annette M., Horn, Heike, Hansmann, Martin L., Pott, Christiane, Unterhalt, Michael, Schmidt, Christian, Dreyling, Martin, Alizadeh, Ash A., Hiddemann, Wolfgang, Hoster, Eva, Weigert, Oliver ^*

Source: In Blood Advances 22 September 2020 4(18):4451-4462

Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma

Authors: Bararia, Deepak, Hildebrand, Johannes A., Stolz, Sebastian, Haebe, Sarah, Alig, Stefan, Trevisani, Christopher P., Osorio-Barrios, Francisco, Bartoschek, Michael D., Mentz, Michael, Pastore, Alessandro, Gaitzsch, Erik, Heide, Michael, Jurinovic, Vindi, Rautter, Katharina, Gunawardana, Jay, Sabdia, Muhammed B., Szczepanowski, Monika, Richter, Julia, Klapper, Wolfram, Louissaint, Abner, Jr., Ludwig, Christina, Bultmann, Sebastian, Leonhardt, Heinrich, Eustermann, Sebastian, Hopfner, Karl-Peter, Hiddemann, Wolfgang, von Bergwelt-Baildon, Michael, Steidl, Christian, Kridel, Robert, Tobin, Joshua W.D., Gandhi, Maher K., Weinstock, David M., Schmidt-Supprian, Marc, Sárosi, Menyhárt B., Rudelius, Martina, Passerini, Verena, Mautner, Josef, Weigert, Oliver

Source: In Cell Reports 5 May 2020 31(5)

Localized- and advanced-stage follicular lymphomas differ in their gene expression profiles

Authors: Staiger, Annette M. ^{1, 2, 3, *}, Hoster, Eva ^{4, *}, Jurinovic, Vindi ⁴, Winter, Stefan ^{2, 3}, Leich, Ellen ^{5, 6}, Kalla, Claudia ^{2, 3}, Möller, Peter ⁷, Bernd, Heinz-Wolfram ⁸, Feller, Alfred C. ⁸, Koch, Karoline ⁹, Klapper, Wolfram ⁹, Stein, Harald ¹⁰, Hansmann, Martin-Leo ¹¹, Hartmann, Sylvia ¹¹, Dreyling, Martin ⁴, Weigert, Oliver ⁴, Hiddemann, Wolfgang ⁴, Herfarth, Klaus ¹², Rosenwald, Andreas ^{5, 6}, Engelhard, Marianne ¹³, Ott, German ^{1, 1}, Horn, Heike ^{1, 2, 3}

Source: In Blood 16 January 2020 135(3):181-190

Impact of age on clinical risk scores in follicular lymphoma

Authors: Alig, Stefan, Jurinovic, Vindi, Pastore, Alessandro, Haebe, Sarah, Schmidt, Christian, Zoellner, Anna-Katharina, Dreyling, Martin, Unterhalt, Michael, Hoster, Eva, Hiddemann, Wolfgang, Weigert, Oliver

Source: In Blood Advances 9 April 2019 3(7):1033-1038

Genomic alterations important for the prognosis in patients with follicular lymphoma treated in SWOG study S0016

Authors: Qu, Xiaoyu, Li, Hongli, Braziel, Rita M., Passerini, Verena, Rimsza, Lisa M., Hsi, Eric D., Leonard, John P., Smith, Sonali M., Kridel, Robert, Press, Oliver, Weigert, Oliver, LeBlanc, Michael, Friedberg, Jonathan W., Fang, Min ^*

Source: In Blood 3 January 2019 133(1):81-93

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles

Authors: Hellmuth, Johannes C. ^*, Louissaint, Abner, Jr ^*, Szczepanowski, Monika, Haebe, Sarah, Pastore, Alessandro, Alig, Stefan, Staiger, Annette M., Hartmann, Sylvia, Kridel, Robert, Ducar, Matthew D., Koch, Peter, Dreyling, Martin, Hansmann, Martin-Leo, Ott, German, Rosenwald, Andreas, Gascoyne, Randy D., Weinstock, David M., Hiddemann, Wolfgang, Klapper, Wolfram, Weigert, Oliver

Source: In Blood 18 October 2018 132(16):1695-1702

Autologous Stem Cell Transplantation for Patients with Early Progression of Follicular Lymphoma: A Follow-Up Study of 2 Randomized Trials from the German Low Grade Lymphoma Study Group

Authors: Jurinovic, Vindi, Metzner, Bernd, Pfreundschuh, Michael, Schmitz, Norbert, Wandt, Hannes, Keller, Ulrich, Dreger, Peter, Dreyling, Martin, Hiddemann, Wolfgang, Unterhalt, Michael, Hoster, Eva, Weigert, Oliver ^*

Source: In Biology of Blood and Marrow Transplantation June 2018 24(6):1172-1179

FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy

Authors: Mottok, Anja ^*, Jurinovic, Vindi ^*, Farinha, Pedro, Rosenwald, Andreas, Leich, Ellen, Ott, German, Horn, Heike, Klapper, Wolfram, Boesl, Michael, Hiddemann, Wolfgang, Steidl, Christian, Connors, Joseph M., Sehn, Laurie H., Gascoyne, Randy D., Hoster, Eva ^*, Weigert, Oliver ^*, Kridel, Robert ^*

Source: In Blood 11 January 2018 131(2):226-235

Molekulare Klassifikatoren

Authors: Weigert, Oliver, Chapuy, Björn

Source: Onkologe. 25(10):849-858

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125321509.0x000001&indx=1&recIds=ETOCvdc_100125321509.0x000001

The promises and challenges of using gene mutations for patient stratification in follicular lymphoma

Authors: Weigert, Oliver, Weinstock, David M.

Source: In Blood 28 September 2017 130(13):1491-1498