Serum lipidomic signatures in patients with varying histological severity of metabolic-dysfunction associated steatotic liver disease

Authors: Muralidharan, Sneha, Lee, Jonathan W.J., Lim, Yee Siang, Muthiah, Mark, Tan, Eunice, Demicioglu, Deniz, Shabbir, Asim, Loo, Wai Mun, Koo, Chieh Sian, Lee, Yin Mei, Soon, Gwyneth, Wee, Aileen, Halisah, Nur, Abbas, Sakinah, Ji, Shanshan, Triebl, Alexander, Burla, Bo, Koh, Hiromi W.L., Chan, Yun Shen, Lee, Mei Chin, Ng, Huck Hui, Wenk, Markus R., Torta, Federico, Dan, Yock Young

Source: In Metabolism January 2025 162

Utility of AI digital pathology as an aid for pathologists scoring fibrosis in MASH

Authors: Abdurrachim, Desiree ^{1, ⁎}, Lek, Serene ², Ong, Charlene Zhi Lin ¹, Wong, Chun Kit ¹, Zhou, Yongqi ¹, Wee, Aileen ³, Soon, Gwyneth ³, Kendall, Timothy J. ⁴, Idowu, Michael O. ⁵, Hendra, Christopher ¹, Saigal, Ashmita ⁶, Krishnan, Radha ⁷, Chng, Elaine ², Tai, Dean ², Ho, Gideon ², Forest, Thomas ⁸, Raji, Annaswamy ⁹, Talukdar, Saswata ⁶, Chin, Chih-Liang ⁶, Baumgartner, Richard ¹⁰, Engel, Samuel S. ⁹, Ali, Asad Abu Bakar ¹, Kleiner, David E. ¹¹, Sanyal, Arun J. ¹²

Source: In Journal of Hepatology November 2024

Artificial Intelligence Improves Pathologist Agreement for Fibrosis Scores in Nonalcoholic Steatohepatitis Patients

Authors: Soon, Gwyneth S.T., Liu, Feng, Leow, Wei-Qiang, Wee, Aileen, Wei, Lai, Sanyal, Arun J.

Source: In Clinical Gastroenterology and Hepatology July 2023 21(7):1940-1942

Modification of the AJCC/UICC 8th edition staging system for intrahepatic cholangiocarcinoma: proposal for an alternative staging system from cholangiocarcinoma-prevalent Northeast Thailand

Authors: Sa-Ngiamwibool, Prakasit, Aphivatanasiri, Chaiwat, Sangkhamanon, Sakkarn, Intarawichian, Piyapharom, Kunprom, Waritta, Thanee, Malinee, Prajumwongs, Piya, Loilome, Watcharin, Khuntikeo, Narong, Titapun, Attapol, Jareanrat, Apiwat, Thanasukarn, Vasin, Srisuk, Tharatip, Luvira, Vor, Eurboonyanun, Kulyada, Promsorn, Julaluck, Wee, Aileen, Koonmee, Supinda

Source: In HPB November 2022 24(11):1944-1956

Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD

Authors: Brunt, Elizabeth M., Clouston, Andrew D., Goodman, Zachary, Guy, Cynthia, Kleiner, David E., Lackner, Carolin, Tiniakos, Dina G., Wee, Aileen, Yeh, Matthew, Leow, Wei Qiang, Chng, Elaine, Ren, Yayun, Boon Bee, George Goh, Powell, Elizabeth E., Rinella, Mary, Sanyal, Arun J., Neuschwander-Tetri, Brent, Younossi, Zobair, Charlton, Michael, Ratziu, Vlad, Harrison, Stephen A., Tai, Dean, Anstee, Quentin M.

Source: Journal of hepatology. 76(5):1030-1041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179671393.0x000001&indx=1&recIds=ETOCvdc_100179671393.0x000001

Automated scoring of liver fibrosis through combined features from different collagen groups

Authors: Xu, Shuoyu, Tai, Dean, Wee, Aileen, Welsch, Roy, So, Peter, Yu, Hanry, Rajapakse, Jagath

Source: 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE. :4503-4506 Aug, 2011

Relation: 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

A High Serum Level of Taurocholic Acid Is Correlated With the Severity and Resolution of Drug-induced Liver Injury

Authors: Tian, Qiuju, Yang, Ruiyuan, Wang, Yan, Liu, Jimin, Wee, Aileen, Saxena, Romil, Wang, Lan, Li, Min, Liu, Liwei, Shan, Shan, Kong, Yuanyuan, Ma, Hong, Ou, Xiaojuan, You, Hong, Zhao, Xinyan, Jia, Jidong

Source: In Clinical Gastroenterology and Hepatology May 2021 19(5):1009-1019

Predicting HCC Response to Multikinase Inhibitors With In Vivo Cirrhotic Mouse Model for Personalized Therapy

Authors: Huang, Daniel Q., Muthiah, Mark D., Zhou, Lei, Jumat, Halisah, Tan, Wan Xin, Lee, Guan Huei, Lim, Seng Gee, Kow, Alfred, Bonney, Glenn, Shridhar, Iyer, Lim, Yi Ting, Wee, Aileen, Pang, Yin Huei, Soon, Gwyneth, Chow, Pierce, Dan, Yock Young

Source: In Cellular and Molecular Gastroenterology and Hepatology 2021 11(5):1313-1325

Liver biopsy in the quantitative assessment of liver fibrosis in nonalcoholic fatty liver disease

Authors: Ting Soon, Gwyneth, Wee, Aileen

Source: Indian journal of pathology & microbiology. 64(5):104-111

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121651230.0x000001&indx=1&recIds=ETOCvdc_100121651230.0x000001

Updates in the quantitative assessment of liver fibrosis for nonalcoholic fatty liver disease: Histological perspective

Authors: Soon, Gwyneth, Wee, Aileen

Source: Clinical and molecular hepatology. 27(1):44-57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630873330&indx=1&recIds=ETOCRN630873330

Persistent Low Level of Hepatitis B Virus Promotes Fibrosis Progression During Therapy

Authors: Sun, Yameng, Wu, Xiaoning, Zhou, Jialing, Meng, Tongtong, Wang, Bingqiong, Chen, Shuyan, Liu, Hui, Wang, Tailing, Zhao, Xinyan, Wu, Shanshan, Kong, Yuanyuan, Ou, Xiaojuan, Wee, Aileen, Theise, Neil D., Qiu, Chao, Zhang, Wenhong, Lu, Fengmin, Jia, Jidong, You, Hong

Source: In Clinical Gastroenterology and Hepatology October 2020 18(11):2582-2591

STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease

Authors: Wang, Xiaoxiao, Rao, Huiying, Zhao, Jingmin, Wee, Aileen, Li, Xiaohe, Fei, Ran, Huang, Rui, Wu, Chaodong, Liu, Feng ^*, Wei, Lai ^**

Source: In Laboratory Investigation April 2020 100(4):542-552

A new glutamine synthetase index to evaluate hepatic lobular restoration in advanced fibrosis during anti‐HBV therapy

Authors: Chen, Shuyan, Wang, Bingqiong, Zhou, Jialing, Wu, Xiaoning, Meng, Tongtong, Liu, Hui, Wang, Tailing, Zhao, Xinyan, Wu, Shanshan, Kong, Yuanyuan, Ou, Xiaojuan, Jia, Jidong, Wee, Aileen, You, Hong, Sun, Yameng

Source: Journal of medical virology. 95(2)

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Histologic pattern is better correlated with clinical outcomes than biochemical classification in patients with drug-induced liver injury

Authors: Tian, Qiu-ju, Zhao, Xin-yan, Wang, Yan, Wee, Aileen, Soon, Gwyneth Shook Ting, Gouw, Annette S.H., Li, Min, Yang, Rui-yuan, Wang, Lan, Wang, Qian-yi, Duan, Wei-jia, Wang, Yu, Wang, Xiao-ming, Kong, Yuan-yuan, Ou, Xiao-juan, You, Hong, Jia, Ji-dong

Source: In Modern Pathology December 2019 32(12):1795-1805

Clinicopathological features of Bu Gu Zhi‐induced liver injury, a long‐term follow‐up cohort study

Authors: Wang, Lan, Wang, Yan, Wee, Aileen, Soon, Gwyneth, Gouw, Annette S. H., Yang, Ruiyuan, Tian, Qiuju, Liu, Liwei, Ma, Hong, Zhao, Xinyan

Source: Liver international. 40(3):571-580

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QFIBS: An Automated Technique for Quantitative Evaluation of Fibrosis, Inflammation, Ballooning, and Steatosis in Patients With Nonalcoholic Steatohepatitis

Authors: Liu, Feng, Goh, George Boon‐Bee, Tiniakos, Dina, Wee, Aileen, Leow, Wei‐Qiang, Zhao, Jing‐Min, Rao, Hui‐Ying, Wang, Xiao‐Xiao, Wang, Qin, Wan, Wei‐Keat, Lim, Kiat‐Hon, Romero‐Gomez, Manuel, Petta, Salvatore, Bugianesi, Elisabetta, Tan, Chee‐Kiat, Harrison, Stephen A., Anstee, Quentin M., Chang, Pik‐Eu Jason, Wei, Lai

Source: Hepatology. 71(6):1953-1966

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The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.

Authors: Low, Zun Siong¹, Chua, Damien¹, Cheng, Hong Sheng¹, Tee, Rachel¹, Tan, Wei Ren¹, Ball, Christopher², Sahib, Norliza Binte Esmail¹, Ng, Ser Sue¹, Qu, Jing³, Liu, Yingzi⁴, Hong, Haiyu⁵, Cai, Chaonong⁵, Rao, Nandini Chilagondanahalli Lakshmi⁶, Wee, Aileen⁷, Muthiah, Mark Dhinesh^8,9,10, Bichler, Zoë¹, Mickelson, Barbara¹¹, Kong, Mei Suen¹, Tay, Vanessa Shiyun¹, Yan, Zhuang¹

Source: Advanced Science; 9/18/2024, Vol. 11 Issue 35, p1-19, 19p

AI Digital Pathology Using qFibrosis Shows Heterogeneity of Fibrosis Regression in Patients with Chronic Hepatitis B and C with Viral Response.

Authors: Liu, Feng, Sun, Yameng, Tai, Dean, Ren, Yayun, Chng, Elaine L. K., Wee, Aileen, Bedossa, Pierre, Huang, Rui, Wang, Jian, Wei, Lai, You, Hong, Rao, Huiying

Source: Diagnostics (2075-4418); Aug2024, Vol. 14 Issue 16, p1837, 10p

Subject Terms: HEPATIC fibrosis, CHRONIC hepatitis C, VIRAL hepatitis, ARTIFICIAL intelligence, CHRONIC hepatitis B, FIBROSIS

Progression and regression of fibrosis in viral hepatitis in the treatment era: the Beijing classification

Authors: Theise, Neil D., Jia, Jidong, Sun, Yameng, Wee, Aileen, You, Hong

Source: In Modern Pathology August 2018 31(8):1191-1200

Validation and utility of artificial intelligence-based zonal annotations as an additional assessment tool for the histopathologic review of fibrosis in non-alcoholic steatohepatitis patients

Authors: Soon, Gwyneth, Wee, Aileen, Leow, Wei Qiang, Chng, Elaine, Tai, Dean, Ren, Yayun, Liu, Feng, Wei, Lai, Sanyal, Arun

Source: Journal of hepatology. 78(S1):S757-S758

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