Hippo Signaling Regulates High-NaCl-Induced Increase in RORγt+ Pro-Inflammatory Lymphocytes.

Authors: Zeeb, Bastian Lukas¹ (AUTHOR), Weber-Stiehl, Saskia^1,2 (AUTHOR), Escudero-Hernández, Celia^1,3 (AUTHOR), Müller, Dominik N.^2,4 (AUTHOR), Maifeld, Andras^1,2 (AUTHOR), Sommer, Felix^1,2 (AUTHOR), Schmitt, Roland³ (AUTHOR), Sievers, Laura Katharina^1,3,4 (AUTHOR) laurakatharina.sievers@uksh.de

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p2143. 14p.

Hexokinase 2 expression in apical enterocytes correlates with inflammation severity in patients with inflammatory bowel disease.

Authors: Weber-Stiehl, Saskia¹ (AUTHOR), Taubenheim, Jan² (AUTHOR), Järke, Lea¹ (AUTHOR), Röcken, Christoph³ (AUTHOR), Schreiber, Stefan⁴ (AUTHOR), Aden, Konrad^1,4 (AUTHOR), Kaleta, Christoph² (AUTHOR), Rosenstiel, Philip¹ (AUTHOR), Sommer, Felix¹ (AUTHOR) f.sommer@ikmb.uni-kiel.de

Source: BMC Medicine. 10/23/2024, Vol. 22 Issue 1, p1-14. 14p.

Subject Terms: *INFLAMMATORY bowel diseases, *CROHN'S disease, *BIOMARKERS, *ULCERATIVE colitis, *RNA sequencing

Epithelial Dual Oxidase 2 Shapes the Mucosal Microbiome and Contributes to Inflammatory Susceptibility.

Authors: Castrillón-Betancur, Juan Camilo, López-Agudelo, Víctor Alonso, Sommer, Nina, Cleeves, Sven, Bernardes, Joana Pimenta, Weber-Stiehl, Saskia, Rosenstiel, Philip, Sommer, Felix

Source: Antioxidants; Oct2023, Vol. 12 Issue 10, p1889, 19p

Subject Terms: DIATOMIC molecules, REACTIVE oxygen species, SODIUM sulfate, DEXTRAN sulfate, CELL communication, FUNCTIONAL analysis

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.

Authors: Fazio, Antonella, Bordoni, Dora, Kuiper, Jan W. P., Weber-Stiehl, Saskia, Stengel, Stephanie T., Arnold, Philipp, Ellinghaus, David, Ito, Go, Tran, Florian, Messner, Berith, Henning, Anna, Bernardes, Joana P., Häsler, Robert, Luzius, Anne, Imm, Simon, Hinrichsen, Finn, Franke, Andre, Huber, Samuel, Nikolaus, Susanna, Aden, Konrad

Source: Nature Communications; 10/21/2022, Vol. 13 Issue 1, p1-19, 19p

Subject Terms: INFLAMMATORY bowel diseases, METHYLTRANSFERASES, INTESTINES, TUMOR necrosis factors, CELL junctions, CATECHOL-O-methyltransferase, DNA

Mitochondrial Function and Microbial Metabolites as Central Regulators of Intestinal Immune Responses and Cancer.

Authors: Weber-Stiehl, Saskia, Järke, Lea, Castrillón-Betancur, Juan Camilo, Gilbert, Felix, Sommer, Felix

Source: Frontiers in Microbiology; 6/29/2022, Vol. 13, p1-9, 9p

Subject Terms: MICROBIAL metabolites, IMMUNE response, MITOCHONDRIA, THERAPEUTICS, CARCINOGENESIS, ENERGY metabolism, INTESTINAL mucosa

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