Identification of recurrent genomic alterations in the apoptotic machinery in chronic lymphocytic leukemia patients treated with venetoclax monotherapy

Authors: Popovic, Relja, Dunbar, Fengjiao, Lu, Charles, Robinson, Kenneth, Quarless, Danjuma, Warder, Scott E., Mukherjee, Nabanita, Pesko, John, Souers, Andrew J., Waring, Jeffrey F., Davids, Matthew S., Tausch, Eugen, Stilgenbauer, Stephan, Ross, Jeremy A., Leverson, Joel D., Kim, Su Young, Chyla, Brenda J.

Source: American journal of hematology. 97(2):E47-E51

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141996939.0x000001&indx=1&recIds=ETOCvdc_100141996939.0x000001

A Genetic Variant in the BCL2 Gene Associates with Adalimumab Response in Hidradenitis Suppurativa Clinical Trials and Regulates Expression of BCL2

Authors: Liu, Mohan, Degner, Jacob, Georgantas, Robert W., Nader, Ahmed, Mostafa, Nael M., Teixeira, Henrique D., Williams, David A., Kirsner, Robert S., Nichols, Anna J., Davis, Justin Wade, Waring, Jeffrey F.

Source: In Journal of Investigative Dermatology March 2020 140(3):574-582

Whole Blood DNA Methylation Changes Are Associated with Anti-TNF Drug Concentration in Patients with Crohn's Disease.

Authors: Lin, Simeng, Hannon, Eilis, Reppell, Mark, Waring, Jeffrey F, Smaoui, Nizar, Pivorunas, Valerie, Guay, Heath, Chanchlani, Neil, Bewshea, Claire, Bai, Benjamin Y H, Kennedy, Nicholas A, Goodhand, James R, Mill, Jonathan, Ahmad, Tariq

Source: Journal of Crohn's & Colitis; Aug2024, Vol. 18 Issue 8, p1190-1201, 12p

Janus Kinase Inhibitor Therapy and Risk of Age-Related Macular Degeneration in Autoimmune Disease.

Authors: Hallak, Joelle A., Abbasi, Ali, Goldberg, Roger A., Modi, Yasha, Zhao, Changgeng, Jing, Yonghua, Chen, Naijun, Mercer, Daniel, Sahu, Soumya, Alobaidi, Ali, López, Francisco J., Luhrs, Keith, Waring, Jeffrey F., den Hollander, Anneke I., Smaoui, Nizar

Source: JAMA Ophthalmology; Aug2024, Vol. 142 Issue 8, p750-758, 9p

Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease

Authors: Kim, Bo‐Hyun, Vasanthakumar, Aparna, Li, Qingqin S., Nudelman, Kelly N.H., Risacher, Shannon L., Davis, Justin W., Idler, Kenneth, Lee, Jong‐Min, Seo, Sang Won, Waring, Jeffrey F., Saykin, Andrew J., Nho, Kwangsik

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191268199.0x000001&indx=1&recIds=ETOCvdc_100191268199.0x000001

Interlaboratory Evaluation of Rat Hepatic Gene Expression Changes Induced by Methapyrilene

Authors: Waring, Jeffrey F., Ulrich, Roger G., Flint, Nick, Morfitt, David, Kalkuhl, Arno, Staedtler, Frank, Lawton, Michael, Beekman, Johanna M., Suter, Laura

Source: Environmental Health Perspectives, 2004 Mar 01. 112(4), 439-448.

Access URL: https://www.jstor.org/stable/3837954

Development of a DNA Microarray for Toxicology Based on Hepatotoxin-Regulated Sequences

Authors: Waring, Jeffrey F., Cavet, Guy, Jolly, Robert A., McDowell, Jeff, Dai, Hongye, Ciurlionis, Rita, Zhang, Chunsheng, Stoughton, Roland, Lum, Pek, Ferguson, Allan, Roberts, Christopher J., Ulrich, Roger G.

Source: Environmental Health Perspectives, 2003 May 01. 111(6), 863-870.

Access URL: https://www.jstor.org/stable/3435129

PTP1B Antisense Oligonucleotide Lowers PTP1B Protein, Normalizes Blood Glucose, and Improves Insulin Sensitivity in Diabetic Mice

Authors: Zinker, Bradley A., Rondinone, Cristina M., Trevillyan, James M., Gum, Rebecca J., Clampit, Jill E., Waring, Jeffrey F., Xie, Nancy, Wilcox, Denise, Jacobson, Peer, Frost, Leigh, Kroeger, Paul E., Reilly, Regina M., Koterski, Sandra, Opgenorth, Terry J., Ulrich, Roger G., Crosby, Seth, Butler, Madeline, Murray, Susan F., McKay, Robert A., Bhanot, Sanjay, Monia, Brett P., Jirousek, Michael R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2002 Aug . 99(17), 11357-11362.

Access URL: https://www.jstor.org/stable/3059573

Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences.

Authors: Ideozu, Justin E., Liu, Mengzhen, Riley-Gillis, Bridget M., Paladugu, Sri R., Rahimov, Fedik, Krishnan, Preethi, Tripathi, Rakesh, Dorr, Patrick, Levy, Hara, Singh, Ashvani, Waring, Jeffrey F., Vasanthakumar, Aparna

Source: Genome Medicine; 3/21/2024, Vol. 16 Issue 1, p1-14, 14p

Subject Terms: EXOMES, CYSTIC fibrosis transmembrane conductance regulator

Geographic Terms: UNITED Kingdom, SOUTH Asia, MIDDLE East

Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients.

Authors: Bai, Benjamin Y H, Reppell, Mark, Smaoui, Nizar, Waring, Jeffrey F, Pivorunas, Valerie, Guay, Heath, Lin, Simeng, Chanchlani, Neil, Bewshea, Claire, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Anderson, Carl A, Group, UK Inflammatory Bowel Disease Pharmacogenetics Study

Source: Journal of Crohn's & Colitis; Mar2024, Vol. 18 Issue 3, p431-445, 15p

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

Authors: Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Waring, Jeffrey F., Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N. H., Faber, Kelley, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J.

Source: Clinical epigenetics. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171715603.0x000001&indx=1&recIds=ETOCvdc_100171715603.0x000001

Functional characterization of a single nucleotide polymorphism associated with Alzheimer's disease in a hiPSC-based neuron model.

Authors: Stolzenburg, Lindsay R., Esmaeeli, Sahar, Kulkarni, Ameya S., Murphy, Erin, Kwon, Taekyung, Preiss, Christina, Bahnassawy, Lamiaa, Stender, Joshua D., Manos, Justine D., Reinhardt, Peter, Rahimov, Fedik, Waring, Jeffrey F., Ramathal, Cyril Y.

Source: PLoS ONE; 9/26/2023, Vol. 18 Issue 9, p1-25, 25p

Subject Terms: SINGLE nucleotide polymorphisms, ALZHEIMER'S disease, INDUCED pluripotent stem cells, GENETIC variation, NEURONS, HAPLOTYPES

Effect of human cerebrospinal fluid sampling frequency on amyloid-β levels

Authors: Li, Jinhe, Llano, Daniel A., Ellis, Teresa, LeBlond, David, Bhathena, Anahita, Jhee, Stanford S., Ereshefsky, Larry, Lenz, Robert, Waring, Jeffrey F.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2012 8(4):295-303

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists

Authors: Li, Jinhe, Mathieu, Suzanne L., Harris, Richard, Ji, Jianguo, Anderson, David J., Malysz, John, Bunnelle, William H., Waring, Jeffrey F., Marsh, Kennan C., Murtaza, Anwar, Olson, Lisa M., Gopalakrishnan, Murali

Source: In Journal of Neuroimmunology 2011 239(1):37-43

Comparing levels of biochemical markers in CSF from cannulated and non-cannulated rats

Authors: Cassar, Steven C., Tovcimak, Ann E., Rustay, Nathan R., Ellis, Teresa A., Hooker, Bradley A., Witte, David G., Li, Jinhe, Buck, Wayne R., Scharf, Dancia, Muller, Uwe, Jeromin, Andreas, Wang, Kevin K.W., Waring, Jeffrey F.

Source: In Journal of Neuroscience Methods 15 October 2010 192(2):249-253

Use of cerebrospinal fluid biomarkers in clinical trials for schizophrenia and depression

Authors: Wan, Hong I, Soares, Holly, Waring, Jeffrey F

Source: Biomarkers in medicine. 6(1):119-129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115563703.0x000001&indx=1&recIds=ETOCvdc_100115563703.0x000001

Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats

Authors: Yang, Yi, Dahly-Vernon, Annette J., Blomme, Eric A.G., Lai-Zhang, Jie, Kempf, Dale J., Marsh, Kennan C., Harrington, Yvette A., Nye, Steven H., Evans, Darin L., Roman, Richard J., Jacob, Howard J., Waring, Jeffrey F.

Source: In The Veterinary Journal 2010 185(1):75-82

Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease

Authors: Rustay, Nathan R., Cronin, Elizabeth A., Curzon, Peter, Markosyan, Stella, Bitner, Robert S., Ellis, Teresa A., Waring, Jeffrey F., Decker, Michael W., Rueter, Lynne E., Browman, Kaitlin E.

Source: In Brain Research 2010 1311:136-147

Development of a toxicogenomics in vitro assay for the efficient characterization of compounds

Authors: Yang, Yi, Abel, Stephen J, Ciurlionis, Rita, Waring, Jeffrey F

Source: Pharmacogenomics. 7(2):177-186

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121261946.0x000001&indx=1&recIds=ETOCvdc_100121261946.0x000001

Chapter 4 - Pharmacogenetics

Authors: Rahimov, Fedik, Waring, Jeffrey F.

Source: In Pharmacovigilance Edition: Second Edition. 2026:31-42