Characterization of erythroferrone structural domains relevant to its iron-regulatory function

Authors: Srole, Daniel N., Jung, Grace, Waring, Alan J., Nemeth, Elizabeta, Ganz, Tomas

Source: In Journal of Biological Chemistry December 2023 299(12)

Combination of pioglitazone, a PPARγ agonist, and synthetic surfactant B-YL prevents hyperoxia-induced lung injury in adult mice lung explants

Authors: Kurihara, Chie, Sakurai, Reiko, Chuang, Tsai-Der, Waring, Alan J., Walther, Frans J., Rehan, Virender K.

Source: In Pulmonary Pharmacology & Therapeutics June 2023 80

Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor.

Authors: Waring, Alan J.^1,2 (AUTHOR) awaring@ucla.edu, Jung, Grace C.-L.¹ (AUTHOR) cljung@mednet.ucla.edu, Sharma, Shantanu K.³ (AUTHOR) ssharma@alumni.caltech.edu, Walther, Frans J.^2,4 (AUTHOR) fjwalther@ucla.edu

Source: International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p10837. 12p.

Subject Terms: *LUNGS, *PEPTIDES, *PULMONARY surfactant, *ANGIOTENSIN converting enzyme, *SURFACE plasmon resonance, *ADULT respiratory distress syndrome, *SUBSTANCE P receptors

Moving on from clinical animal-derived surfactants to peptide-based synthetic pulmonary surfactant.

Authors: Walther, Frans J.^1,2 (AUTHOR), Waring, Alan J.^2,3 (AUTHOR) fjwalther@ucla.edu

Source: American Journal of Physiology: Lung Cellular & Molecular Physiology. Dec2024, Vol. 327 Issue 6, pL883-L889. 7p.

Subject Terms: *CONTINUOUS positive airway pressure, *PREMATURE infants, *RESPIRATORY distress syndrome, *PULMONARY surfactant, *LUNGS, *BRONCHOPULMONARY dysplasia

What is new in synthetic lung surfactant protein technology?

Authors: Walther, Frans J., Zasadzinski, Joseph A., Waring, Alan J.

Source: Expert Review of Respiratory Medicine; Dec2024, Vol. 18 Issue 12, p913-917, 5p

Beyond electrostatics: Antimicrobial peptide selectivity and the influence of cholesterol-mediated fluidity and lipid chain length on protegrin-1 activity

Authors: Henderson, J. Michael, Iyengar, Nishanth S., Lam, Kin Lok H., Maldonado, Eddie, Suwatthee, Tiffany, Roy, Indroneil, Waring, Alan J., Lee, Ka Yee C.

Source: In BBA - Biomembranes 1 October 2019 1861(10)

Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin-1

Authors: Ruchala, Piotr, Waring, Alan J., Cilluffo, Marianne, Whitelegge, Julian P., Gundersen, Cameron B.

Source: In BBA - Biomembranes 1 March 2019 1861(3):677-684

Emulation of the structure of the Saposin protein fold by a lung surfactant peptide construct of surfactant Protein B.

Authors: Waring, Alan J.^1,2 (AUTHOR), Whitelegge, Julian P.³ (AUTHOR), Sharma, Shantanu K.⁴ (AUTHOR), Gordon, Larry M.¹ (AUTHOR), Walther, Frans J.^1,5 (AUTHOR) fjwalther@ucla.edu

Source: PLoS ONE. 11/3/2022, Vol. 17 Issue 11, p1-22. 22p.

Subject Terms: *PEPTIDES, *PULMONARY surfactant, *PROTEIN structure, *PROTEIN folding, *LUNGS, *AMINO acid sequence, *CONOTOXINS

Synthetic Lung Surfactant Treatment for COVID-19 Pneumonia

Authors: Walther, Frans J., Waring, Alan J.

Source: Coronaviruses. 2(1):8-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130264294.0x000001&indx=1&recIds=ETOCvdc_100130264294.0x000001

Conformation and Trimer Association of the Transmembrane Domain of the Parainfluenza Virus Fusion Protein in Lipid Bilayers from Solid-State NMR: Insights into the Sequence Determinants of Trimer Structure and Fusion Activity

Authors: Lee, Myungwoon, Yao, Hongwei, Kwon, Byungsu, Waring, Alan J., Ruchala, Peter, Singh, Chandan, Hong, Mei

Source: In Journal of Molecular Biology 2 March 2018 430(5):695-709

Position of lipidation influences anticancer activity of Smac analogs

Authors: Micewicz, Ewa D., Nguyen, Christine, Micewicz, Alina, Waring, Alan J., McBride, William H., Ruchala, Piotr

Source: Bioorganic & medicinal chemistry letters. 29(13):1628-1635

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081441878.0x000001&indx=1&recIds=ETOCvdc_100081441878.0x000001

Interaction of Antimicrobial Peptide Protegrin with Biomembranes

Authors: Gidalevitz, David, Ishitsuka, Yuji, Muresan, Adrian S., Konovalov, Oleg, Waring, Alan J., Lehrer, Robert I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 May . 100(11), 6302-6307.

Access URL: https://www.jstor.org/stable/3144059

Natural Peptide Antibiotics from Tunicates: Structures, Functions and Potential Uses

Authors: Lehrer, Robert I., Waring, Alan J.

Source: Integrative and Comparative Biology, 2003 Apr 01. 43(2), 313-322.

Access URL: https://www.jstor.org/stable/3884775

Retrocyclin: A Primate Peptide That Protects Cells from Infection by T- and M-Tropic Strains of HIV-1

Authors: Cole, Alexander M., Hong, Teresa, Boo, Lee Ming, Nguyen, Tung, Zhao, Chengquan, Bristol, Greg, Zack, Jerome A., Waring, Alan J., Yang, Otto O., Lehrer, Robert I.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2002 Feb . 99(4), 1813-1818.

Access URL: https://www.jstor.org/stable/3057875

Efficacy, dose-response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs.

Authors: Walther, Frans J.^1,2 (AUTHOR) fjwalther@ucla.edu, Waring, Alan J.^2,3 (AUTHOR), Otieno, Monicah⁴ (AUTHOR), DiBlasi, Robert M.^5,6 (AUTHOR)

Source: Respiratory Research. 4/4/2022, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *PULMONARY surfactant, *CONTINUOUS positive airway pressure, *AEROSOLS, *PREMATURE infants, *LAMBS, *GOAT milk

A Combination of the Aerosolized PPAR-γ Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats

Authors: Sakurai, Reiko, Lee, Cindy, Shen, Humphrey, Waring, Alan J., Walther, Frans J., Rehan, Virender K.

Source: Neonatology. 113(4):296-304

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084718917.0x000001&indx=1&recIds=ETOCvdc_100084718917.0x000001

Oligomeric Structure and Three-Dimensional Fold of the HIV gp41 Membrane-Proximal External Region and Transmembrane Domain in Phospholipid Bilayers

Authors: Kwon, Byungsu, Lee, Myungwoon, Waring, Alan J., Hong, Mei

Source: Journal of the American Chemical Society. 140(26):8246-8259

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN616621852&indx=1&recIds=ETOCRN616621852

Stability of an amphipathic helix-hairpin surfactant peptide in liposomes

Authors: Waring, Alan J., Gupta, Monik, Gordon, Larry M., Fujii, Gary, Walther, Frans J.

Source: In BBA - Biomembranes December 2016 1858(12):3113-3119

Antimicrobial Peptides Share a Common Interaction Driven by Membrane Line Tension Reduction

Authors: Henderson, J. Michael, Waring, Alan J., Separovic, Frances, Lee, Ka Yee C.

Source: In Biophysical Journal 15 November 2016 111(10):2176-2189

Combined effect of synthetic protein, Mini-B, and cholesterol on a model lung surfactant mixture at the air–water interface

Authors: Chakraborty, Aishik, Hui, Erica, Waring, Alan J., Dhar, Prajnaparamita

Source: In BBA - Biomembranes April 2016 1858(4):904-912