Independent associations of sleep and physical activity with cognition are mediated by hippocampal microstructure in middle-aged and older adults

Authors: Callow, Daniel D. ^{a, ⁎}, Spira, Adam P. ^{a, b, c}, Zipunnikov, Vadim ^d, Pettigrew, Corinne ^e, Faria, Andreia ^{f, g}, Wanigatunga, Sarah K. ^c, Albert, Marilyn ^e, Bakker, Arnold ^{a, e}, Soldan, Anja ^e

Source: In Neurobiology of Aging March 2025 147:22-31

Actigraphy estimated sleep moderates the relationship between physical activity and cognition in older adults

Authors: Callow, Daniel D., Zipunnikov, Vadim, Spira, Adam P., Wanigatunga, Sarah K., Pettigrew, Corinne, Albert, Marilyn, Soldan, Anja

Source: In Mental Health and Physical Activity March 2024 26

Sleep and physical activity measures are associated with resting-state network segregation in non-demented older adults

Authors: Callow, Daniel D., Spira, Adam P., Zipunnikov, Vadim, Lu, Hanzhang, Wanigatunga, Sarah K., Rabinowitz, Jill A., Albert, Marilyn, Bakker, Arnold, Soldan, Anja

Source: In NeuroImage: Clinical 2024 43

Objectively measured sleep and physical function: Associations in low-income older adults with disabilities

Authors: Okoye, Safiyyah M., Szanton, Sarah L., Perrin, Nancy A., Nkimbeng, Manka, Schrack, Jennifer A., Han, Hae-Ra, Nyhuis, Casandra, Wanigatunga, Sarah, Spira, Adam P.

Source: In Sleep Health: Journal of the National Sleep Foundation December 2021 7(6):735-741

Associations of personality traits with actigraphic sleep in middle-aged and older adults.

Authors: Rabinowitz, Jill A., Zhou, Yijun, Chen, Diefei, Yue, Yiwei, Rojo-Wissar, Darlynn M., An, Yang, Wanigatunga, Sarah, Schrack, Jennifer A., Zipunnikov, Vadim, Simonsick, Eleanor M., Terracciano, Antonio, Costa, Paul T., Ferrucci, Luigi, Spira, Adam P.

Source: Scientific Reports; 1/9/2025, Vol. 15 Issue 1, p1-10, 10p

Subject Terms: SLEEP duration, MEDICAL sciences, OLDER people, PERSONALITY, SLEEP, MIDDLE-aged persons

A Randomized-Controlled Trial Targeting Cognition in Early Alzheimer's Disease by Improving Sleep with Trazodone (REST).

Authors: Eyob, Estelle, Shaw, Jacob S., Bakker, Arnold, Munro, Cynthia, Spira, Adam, Wu, Mark, Rabinowitz, Jill A., Peters, Matthew, Wanigatunga, Sarah, Zipunnikov, Vadim, Thompson, Richard, Burhanullah, M. Haroon, Leoutsakos, Jeannie-Marie, Rosenberg, Paul, Greenberg, Barry

Source: Journal of Alzheimer's Disease; 2024 Supplement 1, Vol. 101, pS205-S215, 11p

Subject Terms: SLEEP interruptions, SLOW wave sleep, ALZHEIMER'S disease, MILD cognitive impairment, SLEEP stages

Evaluating a novel 24-hour rest/activity rhythm marker of preclinical β-amyloid deposition.

Authors: Spira, Adam P^1,2,3 (AUTHOR) aspira@jhu.edu, Liu, Fangyu⁴ (AUTHOR), Zipunnikov, Vadim⁵ (AUTHOR), Bilgel, Murat⁶ (AUTHOR), Rabinowitz, Jill A⁷ (AUTHOR), An, Yang⁶ (AUTHOR), Di, Junrui⁵ (AUTHOR), Bai, Jiawei⁵ (AUTHOR), Wanigatunga, Sarah K¹ (AUTHOR), Wu, Mark N^8,9 (AUTHOR), Lucey, Brendan P¹⁰ (AUTHOR), Schrack, Jennifer A^3,4 (AUTHOR), Wanigatunga, Amal A^3,4 (AUTHOR), Rosenberg, Paul B² (AUTHOR), Simonsick, Eleanor M⁶ (AUTHOR), Walker, Keenan A⁶ (AUTHOR), Ferrucci, Luigi⁶ (AUTHOR), Resnick, Susan M⁶ (AUTHOR)

Source: Sleep. May2024, Vol. 47 Issue 5, p1-8. 8p.

Comparison of sleep parameters from wrist-worn ActiGraph and Actiwatch devices.

Authors: Liu, Fangyu¹ (AUTHOR) fliu28@jhu.edu, Schrack, Jennifer^1,2 (AUTHOR), Wanigatunga, Sarah K³ (AUTHOR), Rabinowitz, Jill A³ (AUTHOR), He, Linchen^3,4 (AUTHOR), Wanigatunga, Amal A^1,2 (AUTHOR), Zipunnikov, Vadim^2,5 (AUTHOR), Simonsick, Eleanor M⁶ (AUTHOR), Ferrucci, Luigi⁶ (AUTHOR), Spira, Adam P^2,3,7 (AUTHOR)

Source: Sleep. Feb2024, Vol. 47 Issue 2, p1-12. 12p.

Exterior housing conditions are associated with objective measures of poor sleep among low-income older adults with disabilities

Authors: Okoye, Safiyyah M., Spira, Adam P., Perrin, Nancy A., Schrack, Jennifer A., Han, Hae-Ra, Wanigatunga, Sarah, Nyhuis, Casandra, Szanton, Sarah L.

Source: In Sleep Health: Journal of the National Sleep Foundation December 2021 7(6):731-734

Associations Between Objectively Measured Sleep and Cognition: Main Effects and Interactions With Race in Adults Aged ≥50 Years.

Authors: Owusu, Jocelynn T, Rabinowitz, Jill A, Tzuang, Marian, An, Yang, Kitner-Triolo, Melissa, Zipunnikov, Vadim, Wu, Mark N, Wanigatunga, Sarah K, Schrack, Jennifer A, Thorpe, Roland J, Simonsick, Eleanor M, Ferrucci, Luigi, Resnick, Susan M, Spira, Adam P

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Mar2023, Vol. 78 Issue 3, p454-462, 9p

Subject Terms: SLEEP latency, SLEEP duration, MEMORY testing, COGNITION, EXECUTIVE function, SLEEP hygiene, SLEEP

Circadian Rhythm Disturbance in Agitation of Alzheimer's Disease

Authors: Outen, John, Spira, Adam, Wanigatunga, Sarah, Zipunnikov, Vadim, Wu, Mark, Rosenberg, Paul

Source: In The American Journal of Geriatric Psychiatry April 2021 29(4) Supplement:S111-S113

Associations of circadian rest/activity rhythms with cognition in middle-aged and older adults: Demographic and genetic interactions.

Authors: Rabinowitz, Jill A., Yang An, Linchen He, Alfini, Alfonso J., Zipunnikov, Vadim, Wu, Mark N., Wanigatunga, Sarah K., Schrack, Jennifer A., Jackson, Chandra L., Ferrucci, Luigi, Simonsick, Eleanor M., Resnick, Susan M., Spira, Adam P.

Source: Frontiers in Neuroscience; 10/12/2022, Vol. 16, p1-15, 15p

Subject Terms: MIDDLE-aged persons, OLDER people, RACE, COGNITION, COGNITIVE ability, LANGUAGE ability, MORNINGNESS-Eveningness Questionnaire

Brain amyloid burden, sleep, and 24-hour rest/activity rhythms: screening findings from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration Studies.

Authors: Spira, Adam P., Zipunnikov, Vadim, Raman, Rema, Jiyoon Choi, Junrui Di, Jiawei Bai, Carlsson, Cynthia M., Mintzer, Jacobo E., Marshal, Gad A., Porsteinsson, Anton P., Yaari, Roy, Wanigatunga, Sarah K., Kim, John, Wu, Mark N., Aisen, Paul S., Sperling, Reisa A., Rosenberg, Paul B.

Source: Sleep Advances; 2021, Vol. 2 Issue 1, p1-10, 10p

Subject Terms: NONPARAMETRIC statistics, ALZHEIMER'S disease, CONFIDENCE intervals, WECHSLER Adult Intelligence Scale, CIRCADIAN rhythms, ACTIGRAPHY, REGRESSION analysis, MEDICAL screening, FISHER exact test, AMYLOID beta-protein precursor, SLEEP, SLEEP disorders, T-test (Statistics), DESCRIPTIVE statistics, QUESTIONNAIRES, APOLIPOPROTEINS, RESEARCH funding, DATA analysis software, ODDS ratio, LONGITUDINAL method

Associations of actigraphic sleep and circadian rest/activity rhythms with cognition in the early phase of Alzheimer's disease.

Authors: Alfini, Alfonso, Albert, Marilyn, Faria, Andreia V., Soldan, Anja, Pettigrew, Corinne, Wanigatunga, Sarah, Zipunnikov, Vadim, Spira, Adam P.

Source: Sleep Advances; 2021, Vol. 2 Issue 1, p1-10, 10p

Subject Terms: EXECUTIVE function, ALZHEIMER'S disease, MILD cognitive impairment, ACTIGRAPHY, COGNITION, SLEEP, EPISODIC memory, FACTOR analysis, RESEARCH funding

Associations of Actigraphic Sleep Parameters With Fatigability in Older Adults.

Authors: Alfini, Alfonso J, Schrack, Jennifer A, Urbanek, Jacek K, Wanigatunga, Amal A, Wanigatunga, Sarah K, Zipunnikov, Vadim, Ferrucci, Luigi, Simonsick, Eleanor M, Spira, Adam P

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Sep2020, Vol. 75 Issue 9, pe95-e102, 8p

Subject Terms: OLDER people, RATE of perceived exertion, SLEEP, FATIGUE (Physiology), SYMPTOMS

Circadian rhythm disturbance in agitation of Alzheimer's disease.

Authors: Rosenberg, Paul B., Outen, John D., Spira, Adam P., Zipunnikov, Vadim, Wanigatunga, Sarah K., Wu, Mark N.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2021 Supplement S6, Vol. 17, p1-3, 3p

The Potential of Actigraphy to Assess Agitation in Dementia

Authors: Rosenberg, Paul B., Wanigatunga, Sarah K., Spira, Adam P.

Source: In The American Journal of Geriatric Psychiatry August 2019 27(8):870-872

Circadian rhythm disturbance in agitation of Alzheimer's disease: Neuropsychiatry and behavioral neurology/Assessment/Measurement of neuropsychiatric/Behavioral and psychological symptoms.

Authors: Rosenberg, Paul B., Wu, Mark N., Spira, Adam P., Wanigatunga, Sarah K., Zipunnikov, Vadim, Outen, John D.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2020 Supplement S6, Vol. 16 Issue 6, p1-3, 3p

BRAIN AMYLOID BURDEN, SLEEP, AND CIRCADIAN REST/ACTIVITY RHYTHMS: SCREENING FINDINGS FROM A4 AND LEARN

Authors: Rosenberg, Paul B., Zipunnikov, Vadim, Lu, Zeyun, Raman, Rema, Carlsson, Cynthia M., Mintzer, Jacobo E., Marshall, Gad A., Porsteinsson, Anton P., Yaari, Roy, Wanigatunga, Sarah K., Romano, Caitlin, Wu, Mark N., Aisen, Paul S., Sperling, Reisa A., Spira, Adam P.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2018 14(7) Supplement:P1554-P1555

P4‐280: BRAIN AMYLOID BURDEN, SLEEP, AND CIRCADIAN REST/ACTIVITY RHYTHMS: SCREENING FINDINGS FROM A4 AND LEARN.

Authors: Rosenberg, Paul B., Zipunnikov, Vadim, Lu, Zeyun, Raman, Rema, Carlsson, Cynthia M., Mintzer, Jacobo E., Marshall, Gad A., Porsteinsson, Anton P., Yaari, Roy, Wanigatunga, Sarah K., Romano, Caitlin, Wu, Mark N., Aisen, Paul S., Sperling, Reisa A., Spira, Adam P.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jul2018 7S Part 30, Vol. 14, pP1554-P1555, 2p