NAD+ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Authors: Wang, Yu-Jen ^{a, b}, Gaul, Daniel S. ^a, Gorica, Era ^{a, b}, Pahla, Jürgen ^a, Wang, Zeneng ^c, Mohammed, Shafeeq A. ^{a, b}, Dahlby, Tina ^d, Dietrich, Elisa ^e, Osto, Elena ^{d, e, f}, Gariani, Karim ^g, Costantino, Sarah ^{a, b}, Winnik, Stephan ^b, Stein, Sokrates ^{a, b}, Hazen, Stanley L. ^{c, h}, Ruschitzka, Frank ^{a, b}, Auwerx, Johan ⁱ, Matter, Christian M. ^{a, b, ⁎}

Source: In Atherosclerosis May 2025 404

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

Authors: Osborn, Lucas J., Schultz, Karlee, Massey, William, DeLucia, Beckey, Choucair, Ibrahim, Varadharajan, Venkateshwari, Banerjee, Rakhee, Fung, Kevin, Horak, Anthony J., Orabi, Danny, Nemet, Ina, Nagy, Laura E., Wang, Zeneng, Allende, Daniela S., Willard, Belinda B., Sangwan, Naseer, Hajjar, Adeline M., McDonald, Christine, Ahern, Philip P., Hazen, Stanley L., Brown, J. Mark, Claesen, Jan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Nov . 119(48), 1-12.

Access URL: https://www.jstor.org/stable/27208620

Metaorganismal choline metabolism shapes olfactory perception

Authors: Massey, William J., Kay, Kristen E., Jaramillo, Thomas C., rd<%2Fce%3Asup>%22">Horak, Anthony J., 3

Authors: Voigt, Robin M., Wang, Zeneng, Brown, J. Mark, Engen, Phillip A., Naqib, Ankur, Goetz, Christopher G., Hall, Deborah A., Metman, Leo Verhagen, Shaikh, Maliha, Forsyth, Christopher B., Keshavarzian, Ali

Source: In Neurobiology of Disease August 2022 170

The pattern of apolipoprotein A-I lysine carbamylation reflects its lipidation state and the chemical environment within human atherosclerotic aorta

Authors: Battle, Shawna, Gogonea, Valentin, Willard, Belinda, Wang, Zeneng, Fu, Xiaoming, Huang, Ying, Graham, Linda M., Cameron, Scott J., DiDonato, Joseph A., Crabb, John W., Hazen, Stanley L.

Source: In Journal of Biological Chemistry April 2022 298(4)

Gut Microbiota Community Shift with Severity of Coronary Artery Disease

Authors: Hu, Jia-Lu, Yao, Zhi-Feng, Tang, Min-Na, Tang, Chun, Zhao, Xiao-Fan, Su, Xi, Lu, Dan-Bo, Li, Qiu-Rong, Wang, Zhang-Sheng, Yan, Yan, Wang, Zeneng

Source: In Engineering December 2021 7(12):1715-1724

Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice

Authors: Zhang, Xue-Song, Yin, Yue Sandra, Wang, Jincheng, Battaglia, Thomas, Krautkramer, Kimberly, Li, Wei Vivian, Li, Jackie, Brown, Mark, Zhang, Meifan, Badri, Michelle H., Armstrong, Abigail J.S., Strauch, Christopher M., Wang, Zeneng, Nemet, Ina, Altomare, Nicole, Devlin, Joseph C., He, Linchen, Morton, Jamie T., Chalk, John Alex, Needles, Kelly, Liao, Viviane, Mount, Julia, Li, Huilin, Ruggles, Kelly V., Bonneau, Richard A., Dominguez-Bello, Maria Gloria, Bäckhed, Fredrik, Hazen, Stanley L., Blaser, Martin J.

Source: In Cell Host & Microbe 11 August 2021 29(8):1249-1265

Plasma trimethylamine N-oxide (TMAO) levels predict future risk of coronary artery disease in apparently healthy individuals in the EPIC-Norfolk prospective population study

Authors: Tang, W.H. Wilson, Li, Xinmin S., Wu, Yuping, Wang, Zeneng, Khaw, Kay-Tee, Wareham, Nicholas J., Nieuwdorp, Max, Boekholdt, S. Matthijs, Hazen, Stanley L.

Source: In American Heart Journal June 2021 236:80-86

Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression

Authors: Nimer, Nisreen, Choucair, Ibrahim, Wang, Zeneng, Nemet, Ina, Li, Lin, Gukasyan, Janet, Weeks, Taylor L., Alkhouri, Naim, Zein, Nizar, Tang, W.H. Wilson, Fischbach, Michael A., Brown, J. Mark, Allayee, Hooman, Dasarathy, Srinivasan, Gogonea, Valentin, Hazen, Stanley L.

Source: In Metabolism March 2021 116

Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide

Authors: Li, Daniel Y., Wang, Zeneng, Jia, Xun, Yan, Di, Shih, Diana M., Hazen, Stanley L., Lusis, Aldons J., Tang, W.H. Wilson

Source: In JACC: Basic to Translational Science February 2021 6(2):103-115

Exploring the Role of Glycine Metabolism in Coronary Artery Disease: Insights from Human Genetics and Mouse Models.

Authors: Biswas, Subarna, Hilser, James R., Woodward, Nicholas C., Wang, Zeneng, Gukasyan, Janet, Nemet, Ina, Schwartzman, William S., Huang, Pin, Han, Yi, Fouladian, Zachary, Charugundla, Sarada, Spencer, Neal J., Pan, Calvin, Tang, W. H. Wilson, Lusis, Aldons J., Hazen, Stanley L., Hartiala, Jaana A., Allayee, Hooman

Source: Nutrients; Jan2025, Vol. 17 Issue 1, p198, 25p

Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease.

Authors: Li, Zhen, Gu, Min, Zaparte, Aline, Fu, Xiaoming, Mahen, Kala, Mrdjen, Marko, Li, Xinmin S., Yang, Zhihong, Ma, Jing, Thoudam, Themis, Chandler, Kristina, Hesler, Maggie, Heathers, Laura, Gorse, Kiersten, Van, Thanh Trung, Wong, David, Gibson, Aaron M., Wang, Zeneng, Taylor, Christopher M., Quijada, Pearl

Source: Nature Communications; 12/30/2024, Vol. 15 Issue 1, p1-23, 23p

Subject Terms: ALCOHOLISM, VASCULAR endothelial cells, FECAL microbiota transplantation, ENDOTHELIUM diseases, ENDOTHELIAL cells

Circulating Gut Microbe-Derived Metabolites Are Associated with Hepatocellular Carcinoma.

Authors: Banerjee, Rakhee, Wehrle, Chase J., Wang, Zeneng, Wilcox, Jennifer D., Uppin, Vinayak, Varadharajan, Venkateshwari, Mrdjen, Marko, Hershberger, Courtney, Reizes, Ofer, Yu, Jennifer S., Lathia, Justin D., Rotroff, Daniel M., Hazen, Stanley L., Tang, W. H. Wilson, Aucejo, Federico, Brown, J. Mark

Source: Biomedicines; Sep2024, Vol. 12 Issue 9, p1946, 14p

Subject Terms: SURGICAL clinics, HIERARCHICAL clustering (Cluster analysis), HEPATOCELLULAR carcinoma, GUT microbiome, LOGISTIC regression analysis

NMR quantification of trimethylamine-N-oxide in human serum and plasma in the clinical laboratory setting

Authors: Garcia, Erwin, Wolak-Dinsmore, Justyna, Wang, Zeneng, Li, Xinmin S., Bennett, Dennis W., Connelly, Margery A., Otvos, James D., Hazen, Stanley L., Jeyarajah, Elias J.

Source: In Clinical Biochemistry November 2017 50(16-17):947-955