Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab Plus Talazoparib in Patients With SLFN11 Positive Extensive-Stage SCLC: S1929

Authors: Karim, Nagla Abdel ^{a, b, ∗}, Miao, Jieling ^{c, d}, Reckamp, Karen L. ^{e, f}, Gay, Carl M. ^g, Byers, Lauren A. ^g, Zhao, Ying-Qi ^{c, d}, Redman, Mary W. ^{c, d}, Carrizosa, Daniel R. ^h, Wang, Wei-Lien ⁱ, Petty, William J. ^j, Mehta, Kathan ^k, Faller, Bryan A. ^l, Agamah, Edem S. ^m, Kasbari, Samer S. ⁿ, Malisetti, Rajini K. ^o, Kumar, Atul ^p, Schallenkamp, John ^q, Alluri, Krishna C. ^r, Gray, Jhanelle E. ^s, Kelly, Karen ^t

Source: In Journal of Thoracic Oncology March 2025 20(3):383-394

Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation

Authors: Beird, Hannah C. ^a, Cloutier, Jeffrey M. ^b, Gokgoz, Nalan ^c, Eeles, Christopher ^d, Griffin, Anthony M. ^e, Ingram, Davis R. ^b, Wani, Khalida M. ^f, Segura, Rossana Lazcano ^b, Cohen, Luca ^a, Ho, Carl ^a, Wunder, Jay S. ^{c, e}, Andrulis, Irene L. ^{c, g, h}, Futreal, P. Andrew ^a, Haibe-Kains, Benjamin ^{d, i, j}, Lazar, Alexander J. ^{b, f}, Wang, Wei-Lien ^{b, f}, Przybyl, Joanna ^k, Demicco, Elizabeth G. ^{h, l, ∗}

Source: In Laboratory Investigation November 2024 104(11)

TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3

Authors: Lazcano, Rossana, Ingram, Davis R., Panse, Gauri, Lazar, Alexander J., Wang, Wei-Lien, Cloutier, Jeffrey M.

Source: In Human Pathology September 2024 151

Bone mimetic environments support engineering, propagation, and analysis of therapeutic response of patient-derived cells, ex vivo and in vivo

Authors: Paindelli, Claudia, Parietti, Vanessa, Barrios, Sergio, Shepherd, Peter, Pan, Tianhong, Wang, Wei-Lien, Satcher, Robert L., Logothetis, Christopher J., Navone, Nora, Campbell, Matthew T., Mikos, Antonios G., Dondossola, Eleonora

Source: In Acta Biomaterialia 1 April 2024 178:83-92

Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Immunohistochemistry Can Be a Useful Ancillary Tool to Identify Perivascular Epithelioid Cell Tumor

Authors: Wangsiricharoen, Sintawat ^{a, b}, Ingram, Davis R. ^c, Morey, Rohini R. ^c, Wani, Khalida ^c, Lazar, Alexander J. ^{a, c, d}, Wang, Wei-Lien ^{a, c, ∗}

Source: In Modern Pathology March 2024 37(3)

GLI1-Altered Mesenchymal Tumors With ACTB or PTCH1 Fusion: A Molecular and Clinicopathologic Analysis

Authors: Kerr, Darcy A., Cloutier, Jeffrey M., Margolis, Matthew, Mata, Douglas A., Rodrigues Simoes, Nathalie J., Faquin, William C., Dias-Santagata, Dora, Chopra, Shefali, Charville, Gregory W., Wangsiricharoen, Sintawat, Lazar, Alexander J., Wang, Wei-Lien, Rosenberg, Andrew E., Tse, Julie Y.

Source: In Modern Pathology February 2024 37(2)

Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma

Authors: Beird, Hannah C., Wu, Chia-Chin, Nakazawa, Michael, Ingram, Davis, Daniele, Joseph R., Lazcano, Rossana, Little, Latasha, Davies, Christopher, Daw, Najat C., Wani, Khalida, Wang, Wei-Lien, Song, Xingzhi, Gumbs, Curtis, Zhang, Jianhua, Rubin, Brian, Conley, Anthony, Flanagan, Adrienne M., Lazar, Alexander J., Futreal, P. Andrew

Source: In Human Genetics and Genomics Advances 12 October 2023 4(4)

Frequent TRPS1 expression in synovial sarcoma is associated with SS18-SSX fusion oncoprotein activity

Authors: Cloutier, Jeffrey M., Ingram, Davis R., Wani, Khalida, Lazar, Alexander J., Wang, Wei-Lien

Source: In Human Pathology December 2022 130:88-94

Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial

Authors: Somaiah, Neeta ^*, Conley, Anthony P, Parra, Edwin Roger, Lin, Heather, Amini, Behrang, Solis Soto, Luisa, Salazar, Ruth, Barreto, Carmelia, Chen, Honglei, Gite, Swati, Haymaker, Cara, Nassif, Elise F, Bernatchez, Chantale, Mitra, Akash, Livingston, John Andrew, Ravi, Vinod, Araujo, Dejka M, Benjamin, Robert, Patel, Shreyaskumar, Zarzour, Maria A, Sabir, Sharjeel, Lazar, Alexander J, Wang, Wei-Lien, Daw, Najat C, Zhou, Xiao, Roland, Christina L, Cooper, Zachary A, Rodriguez-Canales, Jaime, Futreal, Andrew, Soria, Jean-Charles, Wistuba, Ignacio I, Hwu, Patrick

Source: In The Lancet Oncology September 2022 23(9):1156-1166

Building a pre-surgical multiparametric-MRI-based morphologic, qualitative, semiquantitative, first and high-order radiomic predictive treatment response model for undifferentiated pleomorphic sarcoma to replace RECIST.

Authors: Valenzuela, Raul F.¹ (AUTHOR) rfvalenzuela@mdanderson.org, Duran-Sierra, Elvis¹ (AUTHOR), Antony, Mathew¹ (AUTHOR), Amini, Behrang¹ (AUTHOR), Lo, Sam¹ (AUTHOR), Torres, Keila E.¹ (AUTHOR), Benjamin, Robert S.¹ (AUTHOR), Ma, Jingfei¹ (AUTHOR), Hwang, Ken-Pin¹ (AUTHOR), Stafford, R. Jason¹ (AUTHOR), Araujo, Dejka¹ (AUTHOR), Bishop, Andrew J.¹ (AUTHOR), Ratan, Ravin¹ (AUTHOR), Wang, Wei-Lien¹ (AUTHOR), Espinoza, Jossue¹ (AUTHOR), Valenzuela, Pia V.² (AUTHOR), Wu, Chengyue¹ (AUTHOR), Madewell, John E.¹ (AUTHOR), Murphy Jr, William A.¹ (AUTHOR), Costelloe, Colleen M.¹ (AUTHOR)

Source: Cancer Imaging. 4/26/2025, Vol. 25 Issue 1, p1-15. 15p.

Dedifferentiated chondrosarcoma with minimal or small dedifferentiated component

Authors: Dehner, Carina A., Maloney, Nolan, Amini, Behrang, Jennings, Jack W., McDonald, Douglas J., Wang, Wei-Lien, Chrisinger, J.S.A.

Source: In Modern Pathology July 2022 35(7):922-928

Unusual staining of immunohistochemical markers PAX8 and CDX2 in breast carcinoma: a potential diagnostic pitfall

Authors: Shen, Tiansheng, Zhao, Jun, Zhao, Min, Taggart, Melissa W., Ramalingam, Preetha, Gong, Yun, Wu, Yun, Liu, Hui, Zhang, Jinxia, Resetkova, Erika, Wang, Wei-Lien, Ding, Qingqing, Huo, Lei, Yoon, Esther

Source: In Human Pathology July 2022 125:35-47

The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma

Authors: Zullow, Hayley J., Sankar, Akshay, Ingram, Davis R., Samé Guerra, Daniel D., D’Avino, Andrew R., Collings, Clayton K., Lazcano, Rossana, Wang, Wei-Lien, Liang, Yu, Qi, Jun, Lazar, Alexander J., Kadoch, Cigall

Source: In Molecular Cell 5 May 2022 82(9):1737-1750

Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs

Authors: Hu, Shaomin, Alpert, Lindsay, Cates, Justin M.M., Gonzalez, Raul S., Graham, Rondell, Goldblum, John R., Bakhshwin, Ahmed, Shetty, Sindhu, Wang, Hanlin L., Lollie, Trang, Ma, Changqing, Siddique, Ayesha, Karamchandani, Dipti M., Chen, Fengming, Yantiss, Rhonda K., Hissong, Erika, Chatterjee, Deyali, Chopra, Shefali, Chen, Wei, Vazzano, Jennifer, Wang, Wei-Lien, Ai, Di, Lin, Jingmei, Zheng, Lan, Davis, Jessica L., Brinkerhoff, Brian, Breitbarth, Amanda, Yang, Michelle, Madahian, Sepideh, Panarelli, Nicole, Kuan, Kevin, Pomper, Jonathan, Longacre, Teri, Raghavan, Shyam, Misdraji, Joseph, Cui, Min, Yang, Zhaohai, Savant, Deepika, Harpaz, Noam, Chen, Xiuxu, Resnick, Murray, Wu, Elizabeth Yiru, Klimstra, David, Shia, Jinru, Vyas, Monika, Kakar, Sanjay, Choi, Won-Tak, Robert, Marie E., Li, Hongjie, Lee, Michael, Clark, Ian, Li, Yongchao, Cao, Wenqing, Chang, Qing, Bronner, Mary P., Dong, Zachary, Zhang, Wei, Buehler, Darya, Swanson, Paul E., Mantilla, Jose G., Bellizzi, Andrew M., Feely, Michael, Cooper, Harry S., Nagarathinam, Rajeswari, Pai, Rish, Hammer, Suntrea, Hosseini, Mojgan, Hu, JingJing, Westerhoff, Maria, Cheng, Jerome, Agostini-Vulaj, Diana, Lauwers, Gregory, Ghayouri, Masoumeh, Pezhouh, Maryam K., Zeng, Jianying, Xia, Rong, Yin, Feng, Zhang, Tao, Gao, Zu-hua, Demko, Nadine, Chen, Hannah H., Yu, Sanhong, Hart, John

Source: In Modern Pathology April 2022 35(4):554-563

Global assessment of IRF8 as a novel cancer biomarker

Authors: McQuaid, Daniel C., Panse, Gauri, Wang, Wei-Lien, Pinkus, Geraldine S., Katz, Samuel G., Xu, Mina L.

Source: In Human Pathology April 2022 122:1-10

Expression of TRPS1 in phyllodes tumor and sarcoma of the breast

Authors: Wang, Jing, Wang, Wei-Lien, Sun, Hongxia, Huo, Lei, Wu, Yun, Chen, Hui, Gan, Qiong, Meis, Jeanne M., Maloney, Nolan, Lazar, Alexander J., Yoon, Esther C., Albarracin, Constance T., Krishnamurthy, Savitri, Middleton, Lavinia P., Resetkova, Erika, Yu, Wendong, Tan, Dongfeng, Lu, Wei, Solis Soto, Luisa Maren, Wang, Shufang, Wistuba, Ignacio I., Parwani, Anil V., Prieto, Victor G., Sahin, Aysegul A., Li, Zaibo, Ding, Qingqing

Source: In Human Pathology March 2022 121:73-80

Osteofibrous dysplasia and adamantinoma: A summary of diagnostic challenges and surgical techniques

Authors: El Beaino, Marc, Wang, Wei-Lien, Alaraj, Sami F., Gugala, Zbigniew, Lin, Patrick P.

Source: In Surgical Oncology September 2021 38

Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy

Authors: Terranova, Christopher J., Tang, Ming, Maitituoheti, Mayinuer, Raman, Ayush T., Ghosh, Archit K., Schulz, Jonathan, Amin, Samir B., Orouji, Elias, Tomczak, Katarzyna, Sarkar, Sharmistha, Oba, Junna, Creasy, Caitlin, Wu, Chang-Jiun, Khan, Samia, Lazcano, Rossana, Wani, Khalida, Singh, Anand, Barrodia, Praveen, Zhao, Dongyu, Chen, Kaifu, Haydu, Lauren E., Wang, Wei-Lien, Lazar, Alexander J., Woodman, Scott E., Bernatchez, Chantale, Rai, Kunal

Source: In Cell Reports 20 July 2021 36(3)

RNA expression profiling reveals PRAME, a potential immunotherapy target, is frequently expressed in solitary fibrous tumors

Authors: Wang, Wei-Lien, Gokgoz, Nalan, Samman, Bana, Andrulis, Irene L., Wunder, Jay S., Demicco, Elizabeth G.

Source: In Modern Pathology May 2021 34(5):951-960

Comparison of three FDA-approved diagnostic immunohistochemistry assays of PD-L1 in triple-negative breast carcinoma

Authors: Huang, Xiao, Ding, Qingqing, Guo, Hua, Gong, Yun, Zhao, Jun, Zhao, Min, Sui, Dawen, Wu, Yun, Chen, Hui, Liu, Hui, Zhang, Jinxia, Resetkova, Erika, Moulder, Stacy L., Wang, Wei-Lien, Huo, Lei

Source: In Human Pathology February 2021 108:42-50