Impact of Previous Allogeneic Hematopoietic Stem Cell Transplantation on Chimeric Antigen Receptor (CAR) T Cell Treatment for Relapsed/Refractory Multiple Myeloma

Authors: Kirchberg, Janine ^*, Fischer, Luise ^*, Born, Patrick, Brunner, Franziska, Morgner, Charlotte, Fürst, Daniel, Heyn, Simone, Bach, Enrica, Brueckner, Mandy, Jentzsch, Madlen, Wang, Song-Yau, Böttcher, Sebastian, Franke, Georg-Nikolaus, Schrezenmeier, Hubert, Platzbecker, Uwe, Merz, Maximilian, Vučinić, Vladan

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24(9):e277-e282

30‐Minute infusion of isatuximab in patients with newly diagnosed multiple myeloma: Results of a Phase 1b study analysis.

Authors: Ocio, Enrique M., Perrot, Aurore, Moreau, Philippe, Mateos, Maria‐Victoria, Bringhen, Sara, Martínez‐López, Joaquín, Karlin, Lionel, Wang, Song‐Yau, Oprea, Corina, Li, Yi, Kodas, Ercem, San‐Miguel, Jesus

Source: HemaSphere; Nov2024, Vol. 8 Issue 11, p1-4, 4p

Concomitant and noncanonical JAK2 and MPL mutations in JAK2V617F‐ and MPLW515 L‐positive myelofibrosis

Authors: Schulze, Susann, Stengel, Rayk, Jaekel, Nadja, Wang, Song‐Yau, Franke, Georg–Nikolaus, Roskos, Martin, Schneider, Melanie, Niederwieser, Dietger, Al‐Ali, Haifa Kathrin

Source: Genes, chromosomes & cancer. 58(11):747-755

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094318044.0x000001&indx=1&recIds=ETOCvdc_100094318044.0x000001

P-212: Quantifying the average treatment effect of single vs. tandem autologous stem cell transplantation in newly diagnosed multiple myeloma using causal inference

Authors: Grieb, Nora, Oeser, Alexander, Kubasch, Anne Sophie, Wang, Song-Yau, von Lilienfeld-Toal, Marie, Yomade, Olaposi, Brioli, Annamaria, Strobel, Sarah, Vucinic, Vladan, Franke, Georg-Nikolaus, Heyn, Simone, Hell, Saskia, Schetschorke, Birthe, Jentzsch, Madlen, Schwind, Sebastian, Hochhaus, Andreas, Pönisch, Wolfram, Neumuth, Thomas, Platzbecker, Uwe, Merz, Maximilian

Source: Clinical lymphoma, myeloma & leukemia. 22(S):S151-S152

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169000846.0x000001&indx=1&recIds=ETOCvdc_100169000846.0x000001

Steady‐state versus chemotherapy‐based hematopoietic cell mobilization after anti‐CD38‐based induction therapy in newly diagnosed multiple myeloma.

Authors: Teipel, Raphael, Rieprecht, Susanne, Trautmann‐Grill, Karolin, Röllig, Christoph, Klötzer, Christina, Zimmer, Kristin, Rathaj, Grit, Bach, Enrica, Brückner, Mandy, Heyn, Simone, Wang, Song‐Yau, Jentzsch, Madlen, Schwind, Sebastian, Kretschmann, Theresa, Egger‐Heidrich, Katharina, Remane, Yvonne, Franke, Georg‐Nikolaus, von Bonin, Malte, Bornhäuser, Martin, Platzbecker, Uwe

Source: Transfusion; Nov2023, Vol. 63 Issue 11, p2131-2139, 9p

Subject Terms: MULTIPLE myeloma, GRANULOCYTE-colony stimulating factor, AUTOTRANSPLANTATION, MONOCLONAL antibodies, STEM cell treatment

Cellular dynamics following CAR T cell therapy are associated with response and toxicity in relapsed/refractory myeloma

Authors: Fischer, Luise, Grieb, Nora, Born, Patrick, Weiss, Ronald, Seiffert, Sabine, Boldt, Andreas, Fricke, Stephan, Franz, Paul, Heyn, Simone, Kubasch, Anne Sophie, Baber, Ronny, Weidner, Heike, Wang, Song Yau, Bach, Enrica, Hoffmann, Sandra, Ussmann, Jule, Kirchberg, Janine, Hell, Saskia, Schwind, Sebastian, Metzeler, Klaus H., Herling, Marco, Jentzsch, Madlen, Franke, Georg-Nikolaus, Sack, Ulrich, Reiche, Kristin, Köhl, Ulrike, Platzbecker, Uwe, Vucinic, Vladan, Merz, Maximilian

Source: Leukemia; 20240101, Issue: Preprints p1-11, 11p

Randomized Comparison between Krd and Ktd Induction, Followed By K Maintenance or Control in Transplant Non-Eligible Patients with NDMM: Efficacy and Qol Data (AGMT-MM02 Trial)

Authors: Ludwig, Heinz, Melchardt, Thomas ^*, Sormann, Siegfried ^*, Zojer, Niklas ^*, Andel, Johannes ^*, Hartmann, Bernd L. ^*, Tinchon, Christoph ^*, Gunsilius, Eberhard ^*, Podar, Klaus, Egle, Alexander, Willenbacher, Wolfgang, Wöll, Ewald ^*, Schreder, Martin ^*, Ruckser, Reinhard, Bozic, Boris ^*, Krauth, Maria-Theresa ^*, Petzer, Andreas, Schmitt, Clemens A., Machherndl-Spandl, Sigrid ^*, Agis, Hermine, Fillitz, Michael ^*, Wang, Song-Yau ^*, Knop, Stefan ^*, Kainz, Sarah ^*, Paiva, Bruno ^*, Greil, Richard

Source: In Blood 15 November 2022 140 Supplement 1:10185-10188

Impact of the changing landscape of induction therapy prior to autologous stem cell transplantation in 540 newly diagnosed myeloma patients: a retrospective real-world study.

Authors: Wang, Song-Yau¹ (AUTHOR) Song-Yau.Wang@medizin.uni-leipzig.de, Holzhey, Tanja¹ (AUTHOR), Heyn, Simone¹ (AUTHOR), Zehrfeld, Thomas² (AUTHOR), Fricke, Susann² (AUTHOR), Hoffmann, Franz Albert³ (AUTHOR), Becker, Cornelia³ (AUTHOR), Braunert, Leanthe⁴ (AUTHOR), Edelmann, Thomas⁴ (AUTHOR), Paulenz, Inessa⁵ (AUTHOR), Hitzschke, Marcus⁶ (AUTHOR), Flade, Franziska⁷ (AUTHOR), Schwarzer, Andreas⁷ (AUTHOR), Fenchel, Klaus⁸ (AUTHOR), Franke, Georg-Nikolaus¹ (AUTHOR), Vucinic, Vladan¹ (AUTHOR), Jentzsch, Madlen¹ (AUTHOR), Schwind, Sebastian¹ (AUTHOR), Hell, Saskia¹ (AUTHOR), Backhaus, Donata¹ (AUTHOR)

Source: Journal of Cancer Research & Clinical Oncology. Jul2023, Vol. 149 Issue 7, p3739-3752. 14p.

Subject Terms: *STEM cell transplantation, *PLASMA cell leukemia, *LANDSCAPE changes, *CARDIAC amyloidosis, *MULTIPLE myeloma, *PREDNISOLONE

P-185: Impact of the changing landscape of induction therapy prior to autologous stem cell transplantation in 540 myeloma patients: a retrospective real-world study

Authors: Wang, Song-Yau, Holzhey, Tanja, Heyn, Simone, Zehrfeld, Thomas, Fricke, Susann, Hoffmann, Franz Albert, Becker, Cornelia, Braunert, Leanthe, Edelmann, Thomas, Paulenz, Inessa, Hitzschke, Markus, Flade, Franziska, Schwarzer, Andreas, Fenchel, Klaus, Franke, Georg-Nikolaus, Vucinic, Vladan, Jentzsch, Madlen, Schwind, Sebastian, Lange, Thoralf, Niederwieser, Dietger, Platzbecker, Uwe, Pönisch, Wolfram

Source: Clinical lymphoma, myeloma & leukemia. 21(S2):S138-S139

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164504869.0x000001&indx=1&recIds=ETOCvdc_100164504869.0x000001

Efficacy and safety of isatuximab plus bortezomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma ineligible/with no immediate intent for autologous stem cell transplantation

Authors: Ocio, Enrique M., Perrot, Aurore, Bories, Pierre, San-Miguel, Jesus F., Blau, Igor W., Karlin, Lionel, Martinez-Lopez, Joaquin, Wang, Song-Yau, Bringhen, Sara, Marcatti, Magda, Mateos, María-Victoria, Rodriguez-Otero, Paula, Oliva, Stefania, Nogai, Axel, Le Roux, Nadia, Dong, Liyan, Macé, Sandrine, Gassiot, Matthieu, Fitzmaurice, Thomas, Oprea, Corina, Moreau, Philippe

Source: Leukemia; July 2023, Vol. 37 Issue: 7 p1521-1529, 9p

30-Minute Infusion of Isatuximab in Newly Diagnosed Multiple Myeloma (NDMM) Patients: Results of a Phase 1b Study

Authors: Ocio, Enrique M, Perrot, Aurore, Moreau, Philippe, Mateos, Maria-Victoria, Bringhen, Sara, Martinez-Lopez, Joaquin, Karlin, Lionel, Wolfgang Blau, Igor, Wang, Song-Yau, Martelli, Maurizio, Oprea, Corina, Dong, Yvonne, Kodas, Ercem, San Miguel, Jesus

Source: In Blood 2 November 2023 142 Supplement 1:6717-6717

Increased Bone Turnover and Decreased BCMA Levels in Patients with Response to Anti-BCMA CAR T Cell Therapy in Relapsed/Refractory Multiple Myeloma

Authors: Ussmann, Jule, Fischer, Luise, Born, Patrick, Grieb, Nora, Hoffmann, Sandra, Baber, Ronny, Wang, Song-Yau, Kloetzer, Christina, Heyn, Simone, Herling, Marco, Herling, Carmen, Jentzsch, Madlen, Franke, Georg-Nikolaus, Hofbauer, Lorenz, Platzbecker, Uwe, Vucinic, Vladan, Weidner, Heike, Merz, Maximilian

Source: In Blood 2 November 2023 142 Supplement 1:6643-6643

Cellular Dynamics Following CAR T Cell Therapy Are Associated with Response, Resistance and Cytokine Release Syndrome in Relapsed/Refractory Multiple Myeloma

Authors: Fischer, Luise, Born, Patrick, Weiss, Ronald, Grieb, Nora, Seiffert, Sabine, Boldt, Andreas, Fricke, Stephan, Franz, Paul, Kloetzer, Christina, Heyn, Simone, Baber, Ronny, Wang, Song-Yau, Bach, Enrica, Hoffmann, Sandra, Ussmann, Jule, Kirchberg, Janine, Metzeler, Klaus H, Herling, Marco, Jentzsch, Madlen, Franke, Georg-Nikolaus, Sack, Ulrich, Reiche, Kristin, Koehl, Ulrike, Platzbecker, Uwe, Vucinic, Vladan, Merz, Maximilian

Source: In Blood 2 November 2023 142 Supplement 1:1008-1008

Single Cell Multi-Omic Dissection of Response and Resistance to Chimeric Antigen Receptor T Cells Against BCMA in Relapsed Multiple Myeloma

Authors: Merz, Maximilian, Fischer, Luise, Sia, Jaren, Born, Patrick, Weiss, Ronald, Grieb, Nora, Rade, Michael, Boldt, Andreas, Fricke, Stephan, Franz, Paul, Scolnick, Jonathan, Venkatraman, Lakshmi, Xu, Stacy, Kloetzer, Christina, Heyn, Simone, Kubasch, Anne Sophie, Baber, Ronny, Wang, Song Yau, Bach, Enrica, Hoffmann, Sandra, Ussmann, Jule, Metzeler, Klaus H, Herling, Marco, Herling, Carmen, Jentzsch, Madlen, Franke, Georg-Nikolaus, Sack, Ulrich, Koehl, Ulrike, Reiche, Kristin, Platzbecker, Uwe, Vucinic, Vladan

Source: In Blood 2 November 2023 142 Supplement 1:453-453

Apheresis for Production of Chimeric Antigen Receptor (CAR) T Cells in Patients with Multiple Myeloma - Clinical Factors, Cell Composition and T Cell Senescence

Authors: Vucinic, Vladan, Kirchberg, Janine, Brueckner, Mandy, Born, Patrick, Fischer, Luise, Bach, Enrica, Grieb, Nora, Heyn, Simone, Kloetzer, Christina, Metzeler, Klaus H, Hoffmann, Sandra, Herling, Carmen, Herling, Marco, Franke, Georg-Nikolaus, Schwind, Sebastian, Wang, Song-Yau, Jentzsch, Madlen, Platzbecker, Uwe, Merz, Maximilian

Source: In Blood 2 November 2023 142 Supplement 1:3521-3521

P-170 Stem cell mobilization and autologous stem cell transplantation after induction with bendamustine, prednisone and bortezomib (BPV) in 135 untreated myeloma patients with variable renal function

Authors: Wang, Song-Yau, Fricke, Susann, Holzhey, Tanja, Vucinic, Vladan, Franke, Georg-Nikolaus, Platzbecker, Uwe, Merz, Maximilian, Pönisch, Wolfram

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2023 23 Supplement 2:S129-S129

P-009 Cellular dynamics following CAR T cell therapy are associated with response, resistance and cytokine release syndrome in relapsed/refractory myeloma

Authors: Fischer, Luise, Weiss, Ronald, Grieb, Nora, Rade, Michael, Born, Patrick, Boldt, Andreas, Fricke, Stephan, Franz, Paul, Heyn, Simone, Kubasch, Anne Sophie, Baber, Ronny, Wang, Song Yau, Bach, Enrica, Hoffmann, Sandra, Ussmann, Jule, Metzeler, Klaus H., Herling, Marco, Jentzsch, Madlen, Franke, Georg-Nikolaus, Sack, Ulrich, Reiche, Kristin, Platzbecker, Uwe, Vucinic, Vladan, Merz, Maximilian, Köhl, Ulrike

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2023 23 Supplement 2:S37-S38

OA-04 Single cell multi-omic dissection of response and resistance to chimeric antigen receptor T cells against BCMA in relapsed multiple myeloma

Authors: Grieb, Nora, Weiss, Ronald, Sia, Jaren, Rade, Michael, Fischer, Luise, Born, Patrick, Fricke, Stephan, Franz, Paul, Scolnick, Jonathan, Xu, Stacy, Kubasch, Anne Sophie, Baber, Ronny, Wang, Song Yau, Hoffmann, Sandra, Bach, Enrica, Metzeler, Klaus, Herling, Marco, Jentzsch, Madlen, Franke, Georg-Nikolaus, Sack, Ulrich, Reiche, Kristin, Köhl, Ulrike, Platzbecker, Uwe, Vucinic, Vladan, Merz, Maximilian

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2023 23 Supplement 2:S3-S3

Prognostic impact of rapid involved light chain reduction in first line therapy with Bendamustine, Prednisone and Bortezomib (BPV) in myeloma patients

Authors: Holzhey, Tanja, Wang, Song-Yau, Poenisch, Wolfram

Source: Clinical lymphoma, myeloma & leukemia. 19(S):e236-e237

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091002929.0x000001&indx=1&recIds=ETOCvdc_100091002929.0x000001

Allogeneic hematopoietic cell transplantation (HCT) following reduced-intensity conditioning in patients with acute leukemias

Authors: Niederwieser, Dietger, Gentilini, Chiara, Hegenbart, Ute, Lange, Thoralf, Becker, Cornelia, Wang, Song-Yau, Bartsch, Kristina, Pönisch, Wolfram, Raida, Martin, Al-Ali, Haifa

Source: In Critical Reviews in Oncology and Hematology 2005 56(2):275-281