The endocannabinoid anandamide prevents TH17 programming of activated T lymphocytes while preserving TH1 responses

Authors: Anastasiia Kiprina, Tom Teichmann, Virna Margarita Martín Giménez, Wenqing Xu, Fiona Sailer, Maike Windbergs, Walter Manucha, Andreas Weigert, Ralf P. Brandes

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: AEA, endocannabinoids, T cells, inflammation, lipids, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1528759/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/d4df340f1faf4d76a1db32af2fb1c68b

Mechanistic approaching study in COVID-19 patients treated with high doses of vitamin D

Authors: Mauro G. Silva, Felipe Inserra, Javier Mariani, Laura Antonietti, Myriam Nuñez, Carlos Tajer, León Ferder, Pablo I. F. Inserra, Fernando Ross, Milagro Sánchez Cunto, Magalí Bertelli, Gabriela de Larrañaga, Eliana M. Cela, Daniel H. González Maglio, Mariela M. Gironacci, Walter Manucha

Source: Exploration of Medicine, Vol 4, Iss 2, Pp 246-253 (2023)

Subject Terms: covid-19, sars-cov-2, vitamin d3, angiotensin ii, angiotensin-(1-7), interleukins, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://www.explorationpub.com/Journals/em/Article/1001137; https://doaj.org/toc/2692-3106

Access URL: https://doaj.org/article/617c065bc300439f8c0f5ce12587b150

Novel Possible Biomarkers for the Cardiovascular Disease Prognosis

Authors: Virna Margarita Martín Giménez, Raúl Lelio Sanz, Luciana Jorgelina Mazzei, Roberto Bonafede, Walter Manucha

Source: Pharmaceutical and Biomedical Research, Vol 8, Iss 2, Pp 143-154 (2022)

Subject Terms: heart failure, pulmonary hypertension, c-reactive protein, heat-shock protein 70, biomarkers, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://pbr.mazums.ac.ir/article-1-445-en.html; https://doaj.org/toc/2423-4494

Access URL: https://doaj.org/article/635156f58e0644408aab16ed13043bf1

Melatonin as an Anti-Aging Therapy for Age-Related Cardiovascular and Neurodegenerative Diseases

Authors: Virna Margarita Martín Giménez, Natalia de las Heras, Vicente Lahera, Jesús A. F. Tresguerres, Russel J. Reiter, Walter Manucha

Source: Frontiers in Aging Neuroscience, Vol 14 (2022)

Subject Terms: aging, mitochondria, oxidative stress, inflammation, melatonin, neurodegenerative disease, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.888292/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/d0458c4a20094e77b88923fb97cc68c0

Anti-inflammatory, antioxidant, antihypertensive, and antiarrhythmic effect of indole-3-carbinol, a phytochemical derived from cruciferous vegetables

Authors: Natalia Jorgelina Prado, Daniela Ramirez, Luciana Mazzei, Micaela Parra, Mariana Casarotto, Juan Pablo Calvo, Darío Cuello carrión, Amira Zulma Ponce Zumino, Emiliano Raúl Diez, Alejandra Camargo, Walter Manucha

Source: Heliyon, Vol 8, Iss 2, Pp e08989- (2022)

Subject Terms: Indole-3-carbinol, Inflammation, Hypertension, Oxidative stress, Arrhythmias, Hsp70, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844022002778; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/f934a014143d457e9270ec95dda1f0e6

Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue

Authors: Russel J. Reiter, Ramaswamy Sharma, Alejandro Romero, Walter Manucha, Dun-Xian Tan, Debora Aparecida Pires de Campos Zuccari, Luiz Gustavo de Almeida Chuffa

Source: Antioxidants, Vol 12, Iss 3, p 695 (2023)

Subject Terms: oxidative stress, oocyte, granulosa cells, sirtuins, inflammation, extrapineal melatonin, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/3/695; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/ffd8337c07144e1c9a8d556ecbb3bba1

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: Multicentre randomized controlled clinical trial.

Authors: Javier Mariani, Laura Antonietti, Carlos Tajer, León Ferder, Felipe Inserra, Milagro Sanchez Cunto, Diego Brosio, Fernando Ross, Marcelo Zylberman, Daniel Emilio López, Cecilia Luna Hisano, Sebastián Maristany Batisda, Gabriela Pace, Adrián Salvatore, Jimena Fernanda Hogrefe, Marcela Turela, Andrés Gaido, Beatriz Rodera, Elizabeth Banega, María Eugenia Iglesias, Mariela Rzepeski, Juan Manuel Gomez Portillo, Magalí Bertelli, Andrés Vilela, Leandro Heffner, Verónica Laura Annetta, Lucila Moracho, Maximiliano Carmona, Graciela Melito, María José Martínez, Gloria Luna, Natalia Vensentini, Walter Manucha

Source: PLoS ONE, Vol 17, Iss 5, p e0267918 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/35a33be9a9ef4048a106a4b2f07643f5

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL)

Authors: Javier Mariani, Carlos Tajer, Laura Antonietti, Felipe Inserra, León Ferder, Walter Manucha

Source: Trials, Vol 22, Iss 1, Pp 1-3 (2021)

Subject Terms: COVID-19, Randomised controlled trial, protocol, and vitamin D, SARS-CoV-2, mechanical ventilation, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/797e4c1e6afc4e8981f44d5848436a52

Polymeric Nanomicelles Loaded with Anandamide and Their Renal Effects as a Therapeutic Alternative for Hypertension Treatment by Passive Targeting

Authors: Virna Margarita Martín Giménez, Marcela Analía Moretton, Diego Andrés Chiappetta, María Jimena Salgueiro, Miguel Walter Fornés, Walter Manucha

Source: Pharmaceutics, Vol 15, Iss 1, p 176 (2023)

Subject Terms: anandamide, nanomicelles, hypertension, diuretic, natriuretic, kidneys, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/176; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ddc9f26094fc4e5598fedd4dd88a8009

Differences in RAAS/vitamin D linked to genetics and socioeconomic factors could explain the higher mortality rate in African Americans with COVID-19

Authors: Virna Margarita Martín Giménez, León Ferder, Felipe Inserra, Joxel García, Walter Manucha

Source: Therapeutic Advances in Cardiovascular Disease, Vol 14 (2020)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1753-9455

Access URL: https://doaj.org/article/b300319219f14f7796413b42ea28f1b3

Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications

Authors: Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Adriana Alonso Novais, Vinícius Augusto Simão, Virna Margarita Martín Giménez, Walter Manucha, Debora Aparecida Pires de Campos Zuccari, Russel J. Reiter

Source: Molecules, Vol 26, Iss 12, p 3562 (2021)

Subject Terms: melatonin, nanocarriers, melatonin-loaded nanocarriers, nanoparticles, drug-delivery system, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/12/3562; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/9a95860c87ff4d2cbae1be1110f7ab97

Potential Effects of Melatonin and Micronutrients on Mitochondrial Dysfunction during a Cytokine Storm Typical of Oxidative/Inflammatory Diseases

Authors: Virna Margarita Martín Giménez, Natalia de las Heras, León Ferder, Vicente Lahera, Russel J. Reiter, Walter Manucha

Source: Diseases, Vol 9, Iss 2, p 30 (2021)

Subject Terms: mitochondrial dysfunction, cytokine storm, melatonin, micronutrients, vitamins, minerals, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2079-9721/9/2/30; https://doaj.org/toc/2079-9721

Access URL: https://doaj.org/article/3718856432f4412eae2697adbaba5c93

Implications of Oxidative Stress and Potential Role of Mitochondrial Dysfunction in COVID-19: Therapeutic Effects of Vitamin D

Authors: Natalia de las Heras, Virna Margarita Martín Giménez, León Ferder, Walter Manucha, Vicente Lahera

Source: Antioxidants, Vol 9, Iss 9, p 897 (2020)

Subject Terms: SARS-CoV-2 infection, oxidative stress, mitochondrial dynamics, vitamin D, renin-angiotensin-aldosterone system, COVID-19, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/9/9/897; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/c34c92b6d0ef46e78995c59717e4095d

Wt-1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive Nephropathy

Authors: Luciana Mazzei, Walter Manucha

Source: Advances in Urology, Vol 2013 (2013)

Subject Terms: Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/1687-6369; https://doaj.org/toc/1687-6377

Access URL: https://doaj.org/article/ca9c8c47333c4c3b8fb3a8d21d2e22c1

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