Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts

Authors: Hillary, Robert F., Ng, Hong Kiat, McCartney, Daniel L., Elliott, Hannah R., Walker, Rosie M., Campbell, Archie, Huang, Felicia, Direk, Kenan, Welsh, Paul, Sattar, Naveed, Corley, Janie, Hayward, Caroline, McIntosh, Andrew M., Sudlow, Cathie, Evans, Kathryn L., Cox, Simon R., Chambers, John C., Loh, Marie, Relton, Caroline L., Marioni, Riccardo E., Yousefi, Paul D., Suderman, Matthew

Source: In Cell Genomics 8 May 2024 4(5)

Comprehensive evaluation of smoking exposures and their interactions on DNA methylation

Authors: Heijmans, Bastiaan, ’t Hoen, Peter, van Meurs, Joyce, Jansen, Rick, Franke, Lude, Boomsma, Dorret, Pool, René, van Dongen, Jenny, Hottenga, Jouke, van Greevenbroek, Marleen, Stehouwer, Coen, van der Kallen, Carla, Schalkwijk, Casper, Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje, Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, Van Heemst, Diana, Veldink, Jan, van den Berg, Leonard, van Duijn, Cornelia, Hofman, Bert, Isaacs, Aaron, Uitterlinden, André, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka, Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha, van ‘t Hof, Peter, Deelen, Patrick, Nooren, Irene, Moed, Matthijs, Vermaat, Martijn, Luijk, René, Bonder, Marc, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon, Swertz, Morris, van Zwet, Erik, Hoang, Thanh T., Lee, Yunsung, McCartney, Daniel L., Kersten, Elin T.G., Page, Christian M., Hulls, Paige M., Lee, Mikyeong, Walker, Rosie M., Breeze, Charles E., Bennett, Brian D., Burkholder, Adam B., Ward, James, Brantsæter, Anne Lise, Caspersen, Ida H., Motsinger-Reif, Alison A., Richards, Marie, White, Julie D., Zhao, Shanshan, Richmond, Rebecca C., Magnus, Maria C., Koppelman, Gerard H., Evans, Kathryn L., Marioni, Riccardo E., Håberg, Siri E., London, Stephanie J.

Source: In eBioMedicine February 2024 100

Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use Disorder

Authors: Jung, Jeesun, McCartney, Daniel L., Wagner, Josephin, Yoo, Joyce, Bell, Andrew S., Mavromatis, Lucas A., Rosoff, Daniel B., Hodgkinson, Colin A., Sun, Hui, Schwandt, Melanie, Diazgranados, Nancy, Smith, Alicia K., Michopoulos, Vasiliki, Powers, Abigail, Stevens, Jennifer, Bradley, Bekh, Fani, Negar, Walker, Rosie M., Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Horvath, Steve, Marioni, Riccardo E., Evans, Kathryn L., Goldman, David, Lohoff, Falk W.

Source: Biological psychiatry. 93(4):331-341

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179018666.0x000001&indx=1&recIds=ETOCvdc_100179018666.0x000001

Opioid medication use and blood DNA methylation: epigenome-wide association meta-analysis

Authors: Lee, Mikyeong, Joehanes, Roby, McCartney, Daniel L, Kho, Minjung, Hüls, Anke, Wyss, Annah B, Liu, Chunyu, Walker, Rosie M, R Kardia, Sharon L, Wingo, Thomas S, Burkholder, Adam, Ma, Jiantao, Campbell, Archie, Wingo, Aliza P, Huan, Tianxiao, Sikdar, Sinjini, Keshawarz, Amena, Bennett, David A, Smith, Jennifer A, Evans, Kathryn L, Levy, Daniel, London, Stephanie J

Source: Epigenomics. 14(23):1479-1492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188662334.0x000001&indx=1&recIds=ETOCvdc_100188662334.0x000001

Complex trait methylation scores in the prediction of major depressive disorder

Authors: Barbu, Miruna C., Amador, Carmen, Kwong, Alex S.F., Shen, Xueyi, Adams, Mark J., Howard, David M., Walker, Rosie M., Morris, Stewart W., Min, Josine L., Liu, Chunyu, van Dongen, Jenny, Ghanbari, Mohsen, Relton, Caroline, Porteous, David J., Campbell, Archie, Evans, Kathryn L., Whalley, Heather C., McIntosh, Andrew M.

Source: In eBioMedicine May 2022 79

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome

Authors: Zeng, Yanni, Amador, Carmen, Gao, Chenhao, Walker, Rosie M., Morris, Stewart W., Campbell, Archie, Frkatović, Azra, Madden, Rebecca A, Adams, Mark J., He, Shuai, Bretherick, Andrew D., Hayward, Caroline, Porteous, David J., Wilson, James F., Evans, Kathryn L., McIntosh, Andrew M., Navarro, Pau, Haley, Chris S.

Source: In eBioMedicine December 2021 74

Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

Authors: Green, Claire, Shen, Xueyi, Stevenson, Anna J., Conole, Eleanor L.S., Harris, Mathew A., Barbu, Miruna C., Hawkins, Emma L., Adams, Mark J., Hillary, Robert F., Lawrie, Stephen M., Evans, Kathryn L., Walker, Rosie M., Morris, Stewart W., Porteous, David J., Wardlaw, Joanna M., Steele, J Douglas, Waiter, Gordon D., Sandu, Anca-Larisa, Campbell, Archie, Marioni, Riccardo E., Cox, Simon R., Cavanagh, Jonathan, McIntosh, Andrew M., Whalley, Heather C.

Source: In Brain Behavior and Immunity February 2021 92:39-48

Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6

Authors: Stevenson, Anna J, Gadd, Danni A, Hillary, Robert F, McCartney, Daniel L, Campbell, Archie, Walker, Rosie M, Evans, Kathryn L, Harris, Sarah E, Spires-Jones, Tara L, McRae, Allan F, Visscher, Peter M, McIntosh, Andrew M, Deary, Ian J, Marioni, Riccardo E

Source: Journals of gerontology.Series A.Biological sciences and medical sciences. 76(12):2284-2292

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135718604.0x000001&indx=1&recIds=ETOCvdc_100135718604.0x000001

Birth weight associations with DNA methylation differences in an adult population

Authors: Madden, Rebecca A., McCartney, Daniel L., Walker, Rosie M., Hillary, Robert F., Bermingham, Mairead L., Rawlik, Konrad, Morris, Stewart W., Campbell, Archie, Porteous, David J., Deary, Ian J., Evans, Kathryn L., Hafferty, Jonathan, McIntosh, Andrew M., Marioni, Riccardo E.

Source: Epigenetics. 16(7):783-796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121697810.0x000001&indx=1&recIds=ETOCvdc_100121697810.0x000001

Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT study

Authors: Sun, Yi-Qian, Richmond, Rebecca C, Suderman, Matthew, Min, Josine L, Battram, Thomas, Flatberg, Arnar, Beisvag, Vidar, Nøst, Therese Haugdahl, Guida, Florence, Jiang, Lin, Wahl, Sissel Gyrid Freim, Langhammer, Arnulf, Skorpen, Frank, Walker, Rosie M, Bretherick, Andrew D, Zeng, Yanni, Chen, Yue, Johansson, Mattias, Sandanger, Torkjel M, Relton, Caroline L, Mai, Xiao-Mei

Source: International journal of epidemiology. 50(5):1482-1497

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135756776.0x000001&indx=1&recIds=ETOCvdc_100135756776.0x000001

Methylome-wide association study of early life stressors and adult mental health

Authors: Howard, David M, Pain, Oliver, Arathimos, Ryan, Barbu, Miruna C, Amador, Carmen, Walker, Rosie M, Jermy, Bradley, Adams, Mark J, Deary, Ian J, Porteous, David, Campbell, Archie, Sullivan, Patrick F, Evans, Kathryn L, Arseneault, Louise, Wray, Naomi R, Meaney, Michael, McIntosh, Andrew M, Lewis, Cathryn M

Source: Human molecular genetics. 31(4):651-664

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142896972.0x000001&indx=1&recIds=ETOCvdc_100142896972.0x000001

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

Authors: Bermingham, Mairead L., Walker, Rosie M., Marioni, Riccardo E., Morris, Stewart W., Rawlik, Konrad, Zeng, Yanni, Campbell, Archie, Redmond, Paul, Whalley, Heather C., Adams, Mark J., Hayward, Caroline, Deary, Ian J., Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L.

Source: In EBioMedicine May 2019 43:576-586

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

Authors: McCartney, Daniel L., Stevenson, Anna J., Walker, Rosie M., Gibson, Jude, Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J., Marioni, Riccardo E.

Source: In Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2018 10:429-437

Associations between alcohol use and accelerated biological ageing

Authors: Bøstrand, Sunniva M. K., Vaher, Kadi, Nooij, Laura, Harris, Matthew A., Cole, James H., Cox, Simon R., Marioni, Riccardo E., McCartney, Daniel L., Walker, Rosie M., McIntosh, Andrew M., Evans, Kathryn L., Whalley, Heather C., Wootton, Robyn E., Clarke, Toni‐Kim

Source: Addiction biology. 27(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100143377499.0x000001&indx=1&recIds=ETOCvdc_100143377499.0x000001

Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk

Authors: Hillary, Robert F., Gadd, Danni A., McCartney, Daniel L., Shi, Liu, Campbell, Archie, Walker, Rosie M., Ritchie, Craig W., Deary, Ian J., Evans, Kathryn L., Nevado‐Holgado, Alejo J., Hayward, Caroline, Porteous, David J., McIntosh, Andrew M., Lovestone, Simon, Robinson, Matthew R., Marioni, Riccardo E.

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191267684.0x000001&indx=1&recIds=ETOCvdc_100191267684.0x000001

The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses.

Authors: Walker, Rosie M., Chong, Michael, Perrot, Nicolas, Pigeyre, Marie, Gadd, Danni A., Stolicyn, Aleks, Shi, Liu, Campbell, Archie, Shen, Xueyi, Whalley, Heather C., Nevado-Holgado, Alejo, McIntosh, Andrew M., Heitmeier, Stefan, Rangarajan, Sumathy, O'Donnell, Martin, Smith, Eric E., Yusuf, Salim, Whiteley, William N., Paré, Guillaume

Source: Translational Psychiatry; 5/18/2024, Vol. 14 Issue 1, p1-10, 10p

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles

Authors: Walker, Rosie M., Vaher, Kadi, Bermingham, Mairead L., Morris, Stewart W., Bretherick, Andrew D., Zeng, Yanni, Rawlik, Konrad, Amador, Carmen, Campbell, Archie, Haley, Chris S., Hayward, Caroline, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L.

Source: Genome medicine. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191084926.0x000001&indx=1&recIds=ETOCvdc_100191084926.0x000001

DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health

Authors: Mur, Jure, McCartney, Daniel L., Walker, Rosie M., Campbell, Archie, Bermingham, Mairead L., Morris, Stewart W., Porteous, David J., McIntosh, Andrew M., Deary, Ian J., Evans, Kathryn L., Marioni, Riccardo E.

Source: Alzheimer's & dementia.Translational research & clinical interventions. 6(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140146978.0x000001&indx=1&recIds=ETOCvdc_100140146978.0x000001

Epigenome‐wide analyses identify DNA methylation signatures of dementia risk

Authors: Walker, Rosie M., Bermingham, Mairead L., Vaher, Kadi, Morris, Stewart W., Clarke, Toni‐Kim, Bretherick, Andrew D., Zeng, Yanni, Amador, Carmen, Rawlik, Konrad, Pandya, Kalyani, Hayward, Caroline, Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L.

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120013941.0x000001&indx=1&recIds=ETOCvdc_100120013941.0x000001

An epigenome-wide association study of sex-specific chronological ageing

Authors: McCartney, Daniel L., Zhang, Futao, Hillary, Robert F., Zhang, Qian, Stevenson, Anna J., Walker, Rosie M., Bermingham, Mairead L., Boutin, Thibaud, Morris, Stewart W., Campbell, Archie, Murray, Alison D., Whalley, Heather C., Porteous, David J., Hayward, Caroline, Evans, Kathryn L., Chandra, Tamir, Deary, Ian J., McIntosh, Andrew M., Yang, Jian, Visscher, Peter M., McRae, Allan F., Marioni, Riccardo E.

Source: Genome medicine. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193645401.0x000001&indx=1&recIds=ETOCvdc_100193645401.0x000001