Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma

Authors: Rabin, Erik E., Huang, Jonathan, Kim, Miri, Mozny, Andreas, Lauing, Kristen L., Penco-Campillo, Manon, Zhai, Lijie, Bommi, Prashant, Mi, Xinlei, Power, Erica A., Prabhu, Vikram C., Anderson, Douglas E., Barton, Kevin P., Walunas, Theresa L., Schiltz, Gary E., Amidei, Christina, Sanchez-Gomez, Pilar, Thakkar, Jigisha P., Lukas, Rimas V., Wainwright, Derek A.

Source: In Brain, Behavior, & Immunity - Health July 2024 38

A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer

Authors: Rabin, Erik E., Kim, Miri, Mozny, Andreas, Cardoza, Krislyn, Bell, April C., Zhai, Lijie, Bommi, Prashant, Lauing, Kristen L., King, Amanda L., Armstrong, Terri S., Walunas, Theresa L., Fang, Deyu, Roy, Ishan, Peipert, John D., Sieg, Erica, Mi, Xinlei, Amidei, Christina, Lukas, Rimas V., Wainwright, Derek A.

Source: In Brain, Behavior, & Immunity - Health May 2022 21

Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug

Authors: Bi, Junfeng, Khan, Atif, Tang, Jun, Armando, Aaron M., Wu, Sihan, Zhang, Wei, Gimple, Ryan C., Reed, Alex, Jing, Hui, Koga, Tomoyuki, Wong, Ivy Tsz-Lo, Gu, Yuchao, Miki, Shunichiro, Yang, Huijun, Prager, Briana, Curtis, Ellis J., Wainwright, Derek A., Furnari, Frank B., Rich, Jeremy N., Cloughesy, Timothy F., Kornblum, Harley I., Quehenberger, Oswald, Rzhetsky, Andrey, Cravatt, Benjamin F., Mischel, Paul S.

Source: In Cell Reports 2 November 2021 37(5)

Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)

Authors: Monsen, Paige J., Bommi, Prashant V., Grigorescu, Arabela A., Lauing, Kristen L., Mao, Yingyu, Berardi, Payton, Zhai, Lijie, Ojo, Oluwatomilayo, Penco-Campillo, Manon, Koch, Taylor, Egozi, Michael, Jha, Sonam, Dunne, Sara F., Jiang, Hong, Song, Guiqin, Zhang, Fang, Kregel, Steven, Vaziri-Gohar, Ali, Fanning, Sean W., Sanchez-Gomez, Pilar, Allen, Jacob M., Yamini, Bakhtiar, Lukas, Rimas V., Wainwright, Derek A., Schiltz, Gary E.

Source: Journal of Medicinal Chemistry; February 2025, Vol. 68 Issue: 4 p4961-4987, 27p

Tryptophan metabolism in brain tumors — IDO and beyond

Authors: Platten, Michael, Friedrich, Mirco, Wainwright, Derek A, Panitz, Verena, Opitz, Christiane A

Source: In Current Opinion in Immunology June 2021 70:57-66

The Impact of Beta Blockers on Survival Outcomes in Patients With Non–small-cell Lung Cancer Treated With Immune Checkpoint Inhibitors

Authors: Oh, Michael S., Guzner, Alex, Wainwright, Derek A., Mohindra, Nisha A., Chae, Young K., Behdad, Amir, Villaflor, Victoria M.

Source: In Clinical Lung Cancer January 2021 22(1):e57-e62

Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved

Authors: Hine, Christopher, Wainwright, Derek A., Lathia, Justin D.

Source: Cell chemical biology. 28(12):1665-1668

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151143794.0x000001&indx=1&recIds=ETOCvdc_100151143794.0x000001

Immune Checkpoint Inhibitors in Glioblastoma IDHwt Treatment: A Systematic Review.

Authors: Baskaran, Archit Bharathwaj, Kozel, Olivia A., Venkatesh, Omkar, Wainwright, Derek A., Sonabend, Adam M., Heimberger, Amy B., Lukas, Rimas Vincas

Source: Cancers; Dec2024, Vol. 16 Issue 24, p4148, 27p

Subject Terms: GLIOMAS, T cells, IMMUNOTHERAPY, TREATMENT effectiveness, TUMOR markers, IMMUNE checkpoint inhibitors, SYSTEMATIC reviews, PROGRAMMED cell death 1 receptors, SURVIVAL analysis (Biometry), CANCER patient psychology, DRUG resistance, PHARMACODYNAMICS, EVALUATION

Targeting CD73 to augment cancer immunotherapy

Authors: Roh, Meejeon, Wainwright, Derek A, Wu, Jennifer D, Wan, Yong, Zhang, Bin

Source: In Current Opinion in Pharmacology August 2020 53:66-76

A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors

Authors: Otto-Meyer, Sebastian, DeFaccio, Rian, Dussold, Corey, Ladomersky, Erik, Zhai, Lijie, Lauing, Kristen L., Bollu, Lakshmi R., Amidei, Christina, Lukas, Rimas V., Scholtens, Denise M., Wainwright, Derek A.

Source: In Brain, Behavior, & Immunity - Health February 2020 2

The interplay among psychological distress, the immune system, and brain tumor patient outcomes

Authors: Otto-Meyer, Sebastian, Lumibao, Jan, Kim, Eugene, Ladomersky, Erik, Zhai, Lijie, Lauing, Kristen L, Scholtens, Denise M, Penedo, Frank, Amidei, Christina, Lukas, Rimas V, Wainwright, Derek A

Source: In Current Opinion in Behavioral Sciences August 2019 28:44-50

Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors

Authors: Li, Hongjin, Liu, Tingting, Heinsberg, Lacey W., Lockwood, Mark B., Wainwright, Derek A., Jang, Min Kyeong, Doorenbos, Ardith Z.

Source: Biological research for nursing. 22(4):472-484

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624947847&indx=1&recIds=ETOCRN624947847

Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank

Authors: Chuntova, Pavlina, Chow, Frances, Watchmaker, Payal B, Galvez, Mildred, Heimberger, Amy B, Newell, Evan W, Diaz, Aaron, DePinho, Ronald A, Li, Ming O, Wherry, E John, Mitchell, Duane, Terabe, Masaki, Wainwright, Derek A, Berzofsky, Jay A, Herold-Mende, Christel, Heath, James R, Lim, Michael, Margolin, Kim A, Chiocca, E Antonio, Kasahara, Noriyuki, Ellingson, Benjamin M, Brown, Christine E, Chen, Yvonne, Fecci, Peter E, Reardon, David A, Dunn, Gavin P, Liau, Linda M, Costello, Joseph F, Wick, Wolfgang, Cloughesy, Timothy, Timmer, William C, Wen, Patrick Y, Prins, Robert M, Platten, Michael, Okada, Hideho

Source: Neuro-oncology. 23(3):356-375

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127022892.0x000001&indx=1&recIds=ETOCvdc_100127022892.0x000001

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation.

Authors: Caetano‐Silva, Maria Elisa, Shrestha, Akriti, Duff, Audrey F., Kontic, Danica, Brewster, Patricia C., Kasperek, Mikaela C., Lin, Chia‐Hao, Wainwright, Derek A., Hernandez‐Saavedra, Diego, Woods, Jeffrey A., Bailey, Michael T., Buford, Thomas W., Allen, Jacob M.

Source: Aging Cell; Aug2024, Vol. 23 Issue 8, p1-12, 12p

Subject Terms: GUT microbiome, GASTROINTESTINAL contents, OLD age, IMMUNE response, CALPROTECTIN

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Authors: Kim, Julius W., Kane, J. Robert, Panek, Wojciech K., Young, Jacob S., Rashidi, Aida, Yu, Dou, Kanojia, Deepak, Hasan, Tanwir, Miska, Jason, Gómez-Lim, Miguel A., Ulasov, Ilya V., Balyasnikova, Irina V., Ahmed, Atique U., Wainwright, Derek A., Lesniak, Maciej S.

Source: In Neurotherapeutics 14 October 2018 15(4):1127-1138

Next Steps for Immunotherapy in Glioblastoma.

Authors: Cao, Toni Q.¹ (AUTHOR) toni.cao1@nm.org, Wainwright, Derek A.^2,3,4,5,6 (AUTHOR), Lee-Chang, Catalina^2,3 (AUTHOR), Miska, Jason^2,3 (AUTHOR), Sonabend, Adam M.^2,3 (AUTHOR), Heimberger, Amy B.^2,3 (AUTHOR), Lukas, Rimas V.^1,3 (AUTHOR)

Source: Cancers. Aug2022, Vol. 14 Issue 16, p4023. 30p.

Subject Terms: *GLIOMA treatment, *IMMUNOTHERAPY

Immunotherapy Against Gliomas: is the Breakthrough Near?

Authors: Lukas, Rimas V., Wainwright, Derek A., Horbinski, Craig M., Iwamoto, Fabio M., Sonabend, Adam M.

Source: Drugs. 79(17):1839-1848

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130224776.0x000001&indx=1&recIds=ETOCvdc_100130224776.0x000001

CD73: an emerging checkpoint for cancer immunotherapy

Authors: Chen, Siqi, Wainwright, Derek A, Wu, Jennifer D, Wan, Yong, Matei, Daniela E, Zhang, Yi, Zhang, Bin

Source: Immunotherapy. 11(11):983-997

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185351353.0x000001&indx=1&recIds=ETOCvdc_100185351353.0x000001

Management of glioblastoma in elderly patients

Authors: Young, Jacob S., Chmura, Steven J., Wainwright, Derek A., Yamini, Bakhtiar, Peters, Katherine B., Lukas, Rimas V.

Source: In Journal of the Neurological Sciences 15 September 2017 380:250-255

The Boosting Potential of Bacteria in Cancer Immunotherapy

Authors: Binder, David C., Wainwright, Derek A.

Source: In Trends in Molecular Medicine July 2017 23(7):580-582