α-Dystrobrevin-1 recruits α-catulin to the α 1D -adrenergic receptor/dystrophin-associated protein complex signalosome

Authors: Lyssand, John S., Whiting, Jennifer L., Lee, Kyung-Soon, Kasti, Ryan, Wacker, Jennifer L., Bruchas, Michael R., Miyatake, Mayumi, Langeberg, Lorene K., Chavkin, Charles, Scott, John D., Gardner, Richard G., Adams, Marvin E., Hague, Chris, Lefkowitz, Robert J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Dec . 107(50), 21854-21859.

Access URL: https://www.jstor.org/stable/25756973

Disease-causing Mutation in GPR54 Reveals the Importance of the Second Intracellular Loop for Class A G-protein-coupled Receptor Function

Authors: Wacker, Jennifer L., Feller, David B., Tang, Xiao-Bo, DeFino, Mia C., Namkung, Yuree, Lyssand, John S., Mhyre, Andrew J., Tan, Xu, Jensen, Jill B., Hague, Chris

Source: In Journal of Biological Chemistry 7 November 2008 283(45):31068-31078

Blood Pressure Is Regulated by an α1D-Adrenergic Receptor/Dystrophin Signalosome

Authors: Lyssand, John S., DeFino, Mia C., Tang, Xiao-bo, Hertz, Angie L., Feller, David B., Wacker, Jennifer L., Adams, Marvin E., Hague, Chris

Source: In Journal of Biological Chemistry 4 July 2008 283(27):18792-18800

Histone Deacetylase Inhibition Modulates Kynurenine Pathway Activation in Yeast, Microglia, and Mice Expressing a Mutant Huntingtin Fragment

Authors: Giorgini, Flaviano, Möller, Thomas, Kwan, Wanda, Zwilling, Daniel, Wacker, Jennifer L., Hong, Soyon, Tsai, Li-Chun L., Cheah, Christine S., Schwarcz, Robert, Guidetti, Paolo, Muchowski, Paul J. ^**

Source: In Journal of Biological Chemistry 21 March 2008 283(12):7390-7400

Cysteine String Protein (CSP) Inhibition of N-type Calcium Channels Is Blocked by Mutant Huntingtin

Authors: Miller, Linda C. ^‡, Swayne, Leigh Anne ^{‡, §}, Chen, Lina ^‡, Feng, Zhong-Ping ^{‡, ¶}, Wacker, Jennifer L. ^∥, Muchowski, Paul J. ^{∥, **}, Zamponi, Gerald W. ^{‡, ‡‡}, Braun, Janice E.A. ^{‡, §§}

Source: In Journal of Biological Chemistry 26 December 2003 278(52):53072-53081

Modulation of neurodegeneration by molecular chaperones.

Authors: Muchowski, Paul J.¹ mucho@u.washington.edu, Wacker, Jennifer L.²

Source: Nature Reviews Neuroscience. Jan2005, Vol. 6 Issue 1, p11-22. 12p. 4 Diagrams, 1 Chart.

Subject Terms: *BRAIN diseases, *DEVELOPMENTAL disabilities, *MENTAL illness, *AMYLOID beta-protein, *PROTEINS

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer.

Authors: Wacker, Jennifer L.¹, Zareie, M. Hadi², Hanson Fong², Sarikaya, Mehmet², Muchowski, Paul J.¹ mucho@u.washington.edu

Source: Nature Structural & Molecular Biology. Dec2004, Vol. 11 Issue 12, p1215-1222. 8p.

Subject Terms: *OLIGOMERS, *PROTEINS, *NEURODEGENERATION, *MONOMERS, *MOLECULAR biology, *PROTEOMICS

Differential regulation of GPR54 transcription by specificity protein-1 and partial estrogen response element in mouse pituitary cells

Authors: DeFino, Mia C., Wacker, Jennifer L., Lyssand, John S., Wang, Edith H., Hague, Chris

Source: In Biochemical and Biophysical Research Communications 2010 393(4):603-608

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Chaperone Suppression of Aggregated Protein Toxicity.

Authors: Atassi, M. Zouhair, Berliner, Lawrence J., Chang, Rowen Jui-Yoa, Jörnvall, Hans, Kenyon, Geroge L., Wittman-Liebold, Brigitie, Uversky, Vladimir N., Fink, Anthony L., Wacker, Jennifer L., Muchowski, Paul J.

Source: Protein Misfolding, Aggregation & Conformational Diseases (978-0-387-25918-5); 2006, p137-164, 28p

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α-Dystrobrevin-1 recruits α-catulin to the α1D-adrenergic receptor/dystrophin-associated protein complex signalosome.

Authors: Lyssand, John S., Whiting, Jennifer L., Kyung-Soon Lee, Kastl, Ryan, Wacker, Jennifer L., Brucha, Michael R., Myatake, Mayumi, Langeberg, Lorene K., Chavkin, Charles, Scott, John D., Gardner, Richard G., Adams, Marvin E., Hague, Chris

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/14/2010, Vol. 107 Issue 50, p21854-21859, 6p, 1 Color Photograph, 2 Diagrams, 1 Graph

Subject Terms: PROTEOMICS, MOLECULAR biology, CHEMICAL biology, DYSTROPHIN, G proteins

Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.

Authors: Ehrnhoefer, Dagmar E., Duennwald, Martin, Markovic, Phoebe, Wacker, Jennifer L., Engemann, Sabine, Roark, Margaret, Legleiter, Justin, Marsh, J. Lawrence, Thompson, Leslie M., Lindquist, Susan, Muchowski, Paul J., Wanker, Erich E.

Source: Human Molecular Genetics; Sep2006, Vol. 15 Issue 18, p2743-2751, 9p

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Functional characterization of endogenous GPR54 mutants.

Authors: Wacker, Jennifer L.¹, Feller, David B.¹, Hague, Chris¹

Source: FASEB Journal. Apr2007, Vol. 21 Issue 5, pA422-A422. 1/8p.

Subject Terms: *G proteins, *CELL receptors, *LIGANDS (Biochemistry), *HYPOGONADISM, *GENETIC mutation