Inflammation and macrophage infiltration exacerbate adult incision response by early life injury.

Authors: Wan, Tong¹, Wei, Anqi^1,2, Ding, Zhuofeng¹ dzfzhuofeng@163.com, Gonzalez, Sarel Chavarria¹, Wang, Jian¹, Hou, Xinran¹, Luo, Xiao¹, He, Liqiong¹, Song, Zongbin^1,3 songzb@csu.edu.cn

Source: BMC Anesthesiology. 4/10/2025, Vol. 25 Issue 1, p1-14. 14p.

Subject Terms: *WOUND healing, *WOUNDS & injuries, *RISK assessment, *FLOW cytometry, *MACROPHAGES, *DIPHOSPHONATES, *RESEARCH funding, *ENZYME-linked immunosorbent assay, *NEUROGLIA, *FLUORESCENT antibody technique, *HYPERALGESIA, *RATS, *ANIMAL experimentation, *INFLAMMATION, *STAINS & staining (Microscopy), *PHENOTYPES, *DISEASE risk factors, *DISEASE complications, *CHILDREN, *ADULTS

Nanodiamond: a multifaceted exploration of electrospun nanofibers for antibacterial and wound healing applications.

Authors: Park, Hyeonseo^1,2 (AUTHOR), Patil, Tejal V.^1,2 (AUTHOR), Mo, Changyeun^1,2 (AUTHOR) cymoh100@kangwon.ac.kr, Lim, Ki-Taek^1,2,3 (AUTHOR) ktlim@kangwon.ac.kr

Source: Journal of Nanobiotechnology. 4/9/2025, Vol. 23 Issue 1, p1-30. 30p.

Subject Terms: *WOUND healing, *WOUND care, *CHRONIC wounds & injuries, *THERMAL conductivity, *MASS production, *NANOFIBERS

Immunomarker profiling in human chronic wound swabs reveals IL-1 beta/IL-1RA and CXCL8/CXCL10 ratios as potential biomarkers for wound healing, infection status and regenerative stage.

Authors: Rembe, Julian-Dario¹ (AUTHOR) julian-dario.rembe@med.uni-duesseldorf.de, Garabet, Waseem¹ (AUTHOR), Augustin, Matthias² (AUTHOR), Dissemond, Joachim³ (AUTHOR), Ibing, Wiebke¹ (AUTHOR), Schelzig, Hubert¹ (AUTHOR), Stuermer, Ewa K.⁴ (AUTHOR)

Source: Journal of Translational Medicine. 4/8/2025, Vol. 23 Issue 1, p1-31. 31p.

Subject Terms: *MEDICAL sciences, *WOUND healing, *DIABETIC foot, *CHRONIC wounds & injuries, *WOUND care

Strain‐Dependent Differences in Inflammatory/Immune Activity in Cutaneous Wound Tissue Repair in Rats: The Significance of Body Mass/Proneness to Obesity.

Authors: Kulas, Jelena B.¹ (AUTHOR), Popov Aleksandrov, Aleksandra D.¹ (AUTHOR), Popovic, Dusanka D.¹ (AUTHOR), Malesevic, Anastasija Lj.¹ (AUTHOR), Cakic Milosevic, Maja M.² (AUTHOR), Kataranovski, Milena V.¹ (AUTHOR), Mirkov, Ivana I.¹ (AUTHOR), Tucovic, Dina M.¹ (AUTHOR) dina.mileusnic@ibiss.bg.ac.rs, Giovarelli, Mirella (AUTHOR) mirella.giovarelli@unito.it

Source: Mediators of Inflammation. 3/26/2025, Vol. 2025, p1-15. 15p.

Subject Terms: *PREDIABETIC state, *WOUND healing, *SKIN injuries, *GRANULATION tissue, *GROWTH factors

The effect of biosynthesized silver nanoparticles on Pseudomonas aeruginosa-infected dogs wounds.

Authors: Aldujaily, Ali Hussein¹ (AUTHOR) Alih.aldujaily@uokufa.edu.iq, Hassoon, Kifah Fadhil² (AUTHOR), Hatem, Abdulameer Abid¹ (AUTHOR), Abbas, Murtadha³ (AUTHOR)

Source: PLoS ONE. 3/25/2025, Vol. 20 Issue 3, p1-14. 14p.

Subject Terms: *SKIN injuries, *WOUND healing, *SILVER nanoparticles, *TRIBULUS terrestris, *ANTI-inflammatory agents

miR-138-5p inhibits healing of femoral fracture osteogenesis in rats by modulating osteoblast differentiation via SIRT1/FOXO1 axis.

Authors: Dai, Guangming¹, Jiang, Wei¹, Feng, Bo¹, Zhang, Lan¹ dgm4840@163.com

Source: Journal of Orthopaedic Surgery & Research. 3/14/2025, Vol. 20 Issue 1, p1-10. 10p.

Subject Terms: *WOUND healing, *BIOLOGICAL models, *PROTEINS, *FEMORAL fractures, *OSTEOBLASTS, *RESEARCH funding, *MICRORNA, *BONE growth, *COMPUTED tomography, *POLYMERASE chain reaction, *ENZYME-linked immunosorbent assay, *TRANSCRIPTION factors, *RATS, *ANIMAL experimentation, *WESTERN immunoblotting, *OXIDOREDUCTASES, *TRANSFERASES, *STAINS & staining (Microscopy)

Editorial for the Special Issue "Cutaneous Biology, Molecular Dermatology and Dermatopathology".

Authors: Safai, Bijan^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2694. 5p.

Subject Terms: *THERAPEUTICS, *WOUND healing, *BIOLOGY, *HEALING, *HIDRADENITIS suppurativa, *CELL anatomy, *CELLULAR aging, *SKIN aging

Phytochemical Composition and Wound Healing Properties of Echinacea angustifolia DC. Root Hydroalcoholic Extract.

Authors: Russo, Daniela¹ (AUTHOR), Lela, Ludovica^1,2 (AUTHOR), Benedetto, Nadia¹ (AUTHOR), Faraone, Immacolata^1,2 (AUTHOR), Paternoster, Gianluca¹ (AUTHOR), Valentão, Patricia² (AUTHOR), Milella, Luigi¹ (AUTHOR) luigi.milella@unibas.it, Carmosino, Monica¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2562. 18p.

Subject Terms: *PLANT extracts, *WOUND healing, *ACID derivatives, *NATURAL products, *POLYSACCHARIDES

Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo.

Authors: Fuchs, Benedikt¹ (AUTHOR) Benedikt.Fuchs@med.uni-muenchen.de, Mert, Sinan¹ (AUTHOR), Hofmann, Daniel¹ (AUTHOR), Kuhlmann, Constanze¹ (AUTHOR), Birt, Alexandra¹ (AUTHOR), Wiggenhauser, Paul Severin¹ (AUTHOR), Giunta, Riccardo E¹ (AUTHOR), Chavez, Myra N² (AUTHOR), Nickelsen, Jörg³ (AUTHOR), Schenck, Thilo Ludwig⁴ (AUTHOR), Moellhoff, Nicholas¹ (AUTHOR)

Source: Journal of Tissue Engineering. 3/12/2025, p1-15. 15p.

Subject Terms: *WOUND healing, *FUNCTIONAL integration, *CHRONIC wounds & injuries, *CELL migration, *HYALURONIC acid

Conditioned medium of engineering macrophages combined with soluble microneedles promote diabetic wound healing.

Authors: Wang, HongYu^1,2 (AUTHOR), Wei, BaoHua¹ (AUTHOR), WuLan, Hasi¹ (AUTHOR), Qu, Bin³ (AUTHOR), Li, HuiLong⁴ (AUTHOR), Ren, Jing¹ (AUTHOR), Han, Yan¹ (AUTHOR), Guo, LingLi¹ (AUTHOR) 175673710@qq.com

Source: PLoS ONE. 3/12/2025, Vol. 20 Issue 3, p1-19. 19p.

Subject Terms: *FIBROBLAST growth factor 2, *WOUND healing, *CELL migration, *HYALURONIC acid, *THERAPEUTICS

Esculin promotes skin wound healing in mice and regulates the Wnt/β-catenin signaling pathway.

Authors: Xu, Mian¹ (AUTHOR), Zhang, Mengsi² (AUTHOR) zms123098@163.com, Wu, Jingjing¹ (AUTHOR), Wang, Jinmeng¹ (AUTHOR), Wu, Huaze¹ (AUTHOR), Xu, Xianting¹ (AUTHOR)

Source: CytoJournal. 3/12/2025, Vol. 22, p1-10. 10p.

Subject Terms: *SKIN injuries, *WOUND healing, *BIOLOGICAL models, *PHOSPHORYLATION, *CELL proliferation, *CELLULAR signal transduction, *CYTOSKELETAL proteins, *TREATMENT effectiveness, *FLUORESCENT antibody technique, *MICE, *IMMUNOHISTOCHEMISTRY, *GLYCOSIDES, *ANIMAL experimentation, *WESTERN immunoblotting, *BENZOPYRANS, *COMPARATIVE studies

Spectroscopic Nuclear Magnetic Resonance and Fourier Transform–Infrared Approach Used for the Evaluation of Healing After Surgical Interventions for Patients with Colorectal Cancer: A Pilot Study.

Authors: Șaitiș, Lavinia Raluca^1,2 (AUTHOR), Andras, David^2,3,4 (AUTHOR), Pop, Ioana-Alina^3,5 (AUTHOR), Șaitiș, Cătălin^4,6 (AUTHOR), Crainic, Ramona^1,2,5 (AUTHOR), Fechete, Radu^2,6 (AUTHOR) rfechete@phys.utcluj.ro

Source: Cancers. Mar2025, Vol. 17 Issue 5, p887. 19p.

Subject Terms: *WOUND healing, *INFRARED radiation in medicine, *NUCLEAR magnetic resonance spectroscopy, *RECEIVER operating characteristic curves, *PILOT projects, *COLORECTAL cancer, *TREATMENT effectiveness, *CANCER patients, *DESCRIPTIVE statistics, *CONVALESCENCE, *BLOOD plasma, *FACTOR analysis, *POSTOPERATIVE period, *MACHINE learning, *EVALUATION

Within-trial cost-effectiveness of novel macrophage-regulating treatment on wound healing in patients with diabetic foot ulcers.

Authors: Hsuan-Yu Su¹, Chen-Yi Yang¹, Yi-Hsin Chang¹, Shyi-Gen Chen^2,3, Jui-Ching Chen², Hui-Ju Ho⁴, Huang-Tz Ou^1,5, Shihchen Kuo^1,6 huangtz@mail.ncku.edu.tw

Source: Journal of Food & Drug Analysis. Mar2025, Vol. 33 Issue 1, p21-30. 10p.

Subject Terms: *TREATMENT of diabetic foot, *WOUND healing, *MACROPHAGES, *COST effectiveness, *RESEARCH funding, *BANDAGES & bandaging, *COST benefit analysis, *HEALTH planning, *ATTITUDES of medical personnel, *DIABETIC foot, *SURGICAL dressings, *HEALTH care industry, *BUDGET, *MEDICAL care costs, *HEALTH care rationing

Geographic Terms: TAIWAN

Decellularized tendon patch enhance biological and mechanical healing of large-to-massive rotator cuff tear in a rat chronic model: a comparison study of patch sterilization and storage methods.

Authors: Mao, Yiyang^1,2, Wang, Yirui^2,3, Liu, Shen^2,3, Liu, Zechun^1,2, Yao, Pengling^2,3, Sun, Buhua^1,4 276165453@qq.com, Chen, Can^1,2,4 chencanwow@foxmail.com

Source: Journal of Orthopaedic Surgery & Research. 3/1/2025, Vol. 20 Issue 1, p1-15. 15p.

Subject Terms: *TENDON transplantation, *WOUND healing, *BIOMECHANICS, *POSTOPERATIVE care, *MATERIALS testing, *RESEARCH funding, *COMPUTED tomography, *SEVERITY of illness index, *PRESERVATION of organs, tissues, etc., *ORGAN donation, *DESCRIPTIVE statistics, *STERILIZATION (Disinfection), *MICE, *ROTATOR cuff injuries, *ANIMAL experimentation, *POSTOPERATIVE period, *SURGICAL site, *ETHYLENE oxide, *GAMMA rays

Development of Films for Wound Healing Based on Gelatin and Oil/Water Emulsions as Carriers of Bioactive Compounds.

Authors: Sosa, Ayelen M.^1,2 (AUTHOR) ayelen.sosa@unq.edu.ar, Cottet, Celeste^2,3,4 (AUTHOR), Berin, Belén E.^1,2,3 (AUTHOR), Martínez, Luis M.^1,2,4 (AUTHOR), Peltzer, Mercedes A.^1,3,4 (AUTHOR), Prieto, María J.^1,2 (AUTHOR), Martinez, Carolina S.^1,2,3 (AUTHOR)

Source: Pharmaceutics. Mar2025, Vol. 17 Issue 3, p357. 18p.

Subject Terms: *SILVER nanoparticles, *WOUND healing, *WATER vapor, *BASE oils, *SKIN injuries

Hydrogen-Releasing Micromaterial Dressings: Promoting Wound Healing by Modulating Extracellular Matrix Accumulation Through Wnt/β-Catenin and TGF-β/Smad Pathways.

Authors: Zhao, Pengxiang¹ (AUTHOR), Li, Yufei¹ (AUTHOR), Guo, Boyuan¹ (AUTHOR), Liu, Ziyi¹ (AUTHOR), Zhang, Xujuan¹ (AUTHOR), Liu, Mengyu¹ (AUTHOR), Ma, Xuemei¹ (AUTHOR) xmma@bjut.edu.cn

Source: Pharmaceutics. Mar2025, Vol. 17 Issue 3, p279. 25p.

Subject Terms: *WOUND healing, *TISSUE remodeling, *HYDROGEN storage, *EXTRACELLULAR matrix, *CELL differentiation, *SKIN regeneration

Mixture Containing 5% Polysaccharide Extract of Cerioporus squamosus (Huds.) Quélet, 5% Dexpanthenol, and 0.2% Hyaluronic Acid Shows In Vitro and In Vivo Wound Healing Properties.

Authors: Petrović, Jovana D.¹ (AUTHOR) jovana0303@ibiss.bg.ac.rs, Carević Milićević, Tamara A.¹ (AUTHOR), Glamočlija, Jasmina M.¹ (AUTHOR), Kulaš, Jelena B.¹ (AUTHOR), Mirkov, Ivana I.¹ (AUTHOR)

Source: Pharmaceuticals (14248247). Mar2025, Vol. 18 Issue 3, p416. 17p.

Subject Terms: *WOUND healing, *POLYSACCHARIDES, *STATISTICAL significance, *CYTOTOXINS, *CHRONIC wounds & injuries

Protective Effects of Frankincense Oil on Wound Healing: Downregulating Caspase-3 Expression to Facilitate the Transition from the Inflammatory to Proliferative Phase.

Authors: Venkatesan, Krishnaraju¹ (AUTHOR) kvenkatesan@kku.edu.sa, Sivadasan, Durgaramani² (AUTHOR), Abderrahmen Al Weslati, Moufida³ (AUTHOR), Gayasuddin Mouid, Mohammed^4,5 (AUTHOR), Goyal, Manoj^5,6 (AUTHOR), Bansal, Monika^6,7 (AUTHOR), Salama, Mohamed EL-Dosoky Mohamed⁷ (AUTHOR), Azizullah Ghori, Syed⁸ (AUTHOR), Ahmad, Fazil^1,6 (AUTHOR)

Source: Pharmaceuticals (14248247). Mar2025, Vol. 18 Issue 3, p407. 16p.

Subject Terms: *GAS chromatography/Mass spectrometry (GC-MS), *WOUND healing, *TISSUE remodeling, *BIOMARKERS, *LABORATORY rats

Optimized Hesperidin-Loaded Lipid Nanoparticles with Tea Tree Oil for Enhanced Wound Healing: Formulation, Characterization, and Evaluation.

Authors: Arneth, Borros^1,2 (AUTHOR) borros.arneth@staff.uni-marburg.de, Abdelmonem, Rehab^2,3 (AUTHOR), El-Nabarawi, Mohamed A.^3,4 (AUTHOR), Teaima, Mahmoud Hassan⁴ (AUTHOR), Rashwan, Kareem Omar⁵ (AUTHOR), Soliman, Mohamed A.^1,3 (AUTHOR), Al-Samadi, Inas Essam Ibrahim^2,3 (AUTHOR)

Source: Pharmaceuticals (14248247). Mar2025, Vol. 18 Issue 3, p290. 37p.

Subject Terms: *TEA tree oil, *WOUND healing, *TRANSMISSION electron microscopy, *CYTOTOXINS, *FACTORIAL experiment designs, *ZETA potential

Microenvironment of diabetic foot ulcers: Implications for healing and therapeutic strategies.

Authors: Wang, Jixue¹, Yang, Xirui², Zhou, Tao¹ zwxgzt@163.com, Ma, Haitao¹, Yuan, Xingxing³, Yan, Shuxun⁴, Wang, Siqi⁵

Source: Journal of Research in Medical Sciences. Mar2025, Vol. 30 Issue 3, p1-7. 7p.

Subject Terms: *TREATMENT of diabetic foot, *WOUND healing, *CELL physiology, *IMMUNE system, *DRUG delivery systems, *QUALITY of life, *BLOOD circulation, *INFLAMMATION, *CYTOKINES, *COLLAGEN, *ORGANIC compounds, *HYPOXEMIA