Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response

Authors: Apostolova, Petya, Kreutmair, Stefanie, Toffalori, Cristina, Punta, Marco, Unger, Susanne, Burk, Ann‐Cathrin, Wehr, Claudia, Maas‐Bauer, Kristina, Melchinger, Wolfgang, Haring, Eileen, Hoefflin, Rouven, Shoumariyeh, Khalid, Hupfer, Valerie, Lauer, Eliza Maria, Duquesne, Sandra, Lowinus, Theresa, Gonzalo Núñez, Nicolás, Alberti, Chiara, Costa Pereira, Sara, Merten, Carla Helena, Power, Laura, Weiss, Matthias, Böke, Caroline, Pfeifer, Dietmar, Marks, Reinhard, Bertz, Hartmut, Wäsch, Ralph, Ihorst, Gabriele, Gentner, Bernhard, Duyster, Justus, Boerries, Melanie, Andrieux, Geoffroy, Finke, Juergen, Becher, Burkhard, Vago, Luca, Zeiser, Robert

Source: British journal of haematology. 203(2):264-281

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10-day decitabine versus 3 + 7 chemotherapy followed by allografting in older patients with acute myeloid leukaemia: an open-label, randomised, controlled, phase 3 trial

Authors: Finke, Jürgen, Schaap, Nicolaas Petrus Michael, Zucenka, Andrius, Metzelder, Stephan, Jost, Edgar, Perić, Zinaida, Forghieri, Fabio, Allione, Bernadino, Martelli, Maurizio, Iori, Anna Paola, Wittnebel, Sebastian, Mengarelli, Andrea, Imovilli, Annalisa, Olivieri, Attilio, De Prijck, Bernard José Marie, van der Poel, Marjolein W.M., Junghanß, Christian, Salih, Helmut Rainer, Tafuri, Agostino, Guimarães, José Eduardo, Musso, Maurizio, De Fabritiis, Paolo, Chevallier, Patrice, Selleslag, Dominik Luc, Cascavilla, Nicola, Berneman, Zwi, Jaspers, Aurélie, Zuffa, Eliana, Vanstraelen, Gaëtan, Visani, Giuseppe, Cuijpers, Maria Louisa Henriëtte, De Becker, Ann, Mianulli, Anna Maria, Hackanson, Björn, Mihaylov, Georgi Georgiev, Martinelli, Giovanni, Paolini, Stefania, Zinzani, Pier Luigi, Henkes, Martin, Al-Ali, Haifa Kathrin, La Rosée, Paul, Chierichini, Anna, Cudillo, Laura, Specchia, Giorgina, Šimec, Njetočka Gredelj, Capalbo, Silvana Franca, Spinosa, Giuseppina, Molica, Stefano, de Jonge-Peeters, Susan Dorothé, Lübbert, Michael ^{*, *}, Wijermans, Pierre W ^*, Kicinski, Michal, Chantepie, Sylvain, Van der Velden, Walter J F M, Noppeney, Richard, Griškevičius, Laimonas, Neubauer, Andreas, Crysandt, Martina, Vrhovac, Radovan, Luppi, Mario, Fuhrmann, Stephan, Audisio, Ernesta, Candoni, Anna, Legrand, Olivier, Foà, Robin, Gaidano, Gianluca, van Lammeren-Venema, Danielle, Posthuma, Eduardus F M, Hoogendoorn, Mels, Giraut, Anne, Stevens-Kroef, Marian, Jansen, Joop H, de Graaf, Aniek O, Efficace, Fabio, Ammatuna, Emanuele, Vilque, Jean-Pierre, Wäsch, Ralph, Becker, Heiko, Blijlevens, Nicole, Dührsen, Ulrich, Baron, Frédéric, Suciu, Stefan, Amadori, Sergio, Venditti, Adriano, Huls, Gerwin ^**

Source: In The Lancet Haematology November 2023 10(11):e879-e889

Management of Belantamab Mafodotin–Associated Keratopathy With Rigid Gas-Permeable Corneal Contact Lenses

Authors: Keye, Philip, Engelhardt, Monika, Wäsch, Ralph, Böhringer, Daniel, Reinhard, Thomas

Source: Cornea. 42(6):744-746

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190869531.0x000001&indx=1&recIds=ETOCvdc_100190869531.0x000001

Myosteatosis in multiple myeloma: a key determinant of survival beyond sarcopenia.

Authors: Diallo, Thierno D., Blessing, Ariane Irma Luise, Ihorst, Gabriele, Möller, Mandy Deborah, Jungmann, Pia M., Bamberg, Fabian, Herget, Georg, Wäsch, Ralph, Engelhardt, Monika, Neubauer, Jakob

Source: Skeletal Radiology; Feb2025, Vol. 54 Issue 2, p275-285, 11p

Subject Terms: PROPORTIONAL hazards models, BODY composition, PHYSICAL mobility, OVERALL survival, MULTIPLE myeloma

Optimizing individualized therapy decision-making in multiple myeloma (MM): integration and impact of the Revised Myeloma Comorbidity Index in the MM-tumor board.

Authors: Dreyling, Esther, Ihorst, Gabriele, Reinhardt, Heike, Räder, Jan, Holler, Maximilian, Herget, Georg, Greil, Christine, Wäsch, Ralph, Engelhardt, Monika

Source: Annals of Hematology; Jan2025, Vol. 104 Issue 1, p593-603, 11p

Subject Terms: MULTIPLE myeloma, COMORBIDITY, INDIVIDUALIZED medicine, CLINICAL decision support systems, COHORT analysis, FUNCTIONAL assessment, MEDICAL protocols, HEMATOLOGICAL oncology

The impact of pulmonary function in patients undergoing autologous stem cell transplantation

Authors: Duque-Afonso, Jesús ^*, Ewald, Sophie ^*, Ihorst, Gabriele, Waterhouse, Miguel, Struessmann, Tim, Zeiser, Robert, Wäsch, Ralph, Bertz, Hartmut, Müller-Quernheim, Joachim, Duyster, Justus, Finke, Jürgen, Marks, Reinhard ^†, Engelhardt, Monika ^†

Source: In Blood Advances 9 November 2021 5(21):4327-4337

Physical activity is associated with less comorbidity, better treatment tolerance and improved response in patients with multiple myeloma undergoing stem cell transplantation

Authors: Möller, Mandy-Deborah, Ihorst, Gabriele, Pahl, Antonia, Scheubeck, Sophia, Barsch, Friedrich, Dold, Sandra Maria, Bertz, Hartmut, Arends, Jann, Wäsch, Ralph, Engelhardt, Monika

Source: In Journal of Geriatric Oncology May 2021 12(4):521-530

Comparison of the prognostic significance of 5 comorbidity scores and 12 functional tests in a prospective multiple myeloma patient cohort

Authors: Scheubeck, Sophia, Ihorst, Gabriele, Schoeller, Katja, Holler, Maximilian, Möller, Mandy‐Deborah, Reinhardt, Heike, Wäsch, Ralph, Engelhardt, Monika

Source: Cancer. 127(18):3422-3436

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135934657.0x000001&indx=1&recIds=ETOCvdc_100135934657.0x000001

Carfilzomib, bendamustine, and dexamethasone in patients with advanced multiple myeloma: The EMN09 phase 1/2 study of the European Myeloma Network

Authors: Gay, Francesca, Günther, Andreas, Offidani, Massimo, Engelhardt, Monika, Salvini, Marco, Montefusco, Vittorio, Patriarca, Francesca, Aquino, Sara, Pönisch, Wolfram, Spada, Stefano, Schub, Natalie, Gentili, Silvia, Wäsch, Ralph, Corradini, Paolo, Straka, Christian, Palumbo, Antonio, Einsele, Hermann, Boccadoro, Mario, Sonneveld, Pieter, Gramatzki, Martin

Source: Cancer. 127(18):3413-3421

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134530693.0x000001&indx=1&recIds=ETOCvdc_100134530693.0x000001

Interdisciplinary approach to multiple myeloma – time to diagnosis and warning signs

Authors: Herget, Georg W., Kälberer, Felix, Ihorst, Gabriele, Graziani, Giulia, Klein, Lukas, Rassner, Michael, Gehler, Christian, Jung, Johannes, Schmal, Hagen, Wäsch, Ralph, Engelhardt, Monika

Source: Leukemia & lymphoma. 62(4):891-898

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117919921.0x000001&indx=1&recIds=ETOCvdc_100117919921.0x000001

Geriatric assessments and frailty scores in multiple myeloma patients: a needed tool for individualized treatment?

Authors: Möller, Mandy-Deborah, Gengenbach, Laura, Graziani, Giulia, Greil, Christine, Wäsch, Ralph, Engelhardt, Monika

Source: Current opinion in oncology. 33(6):648-657

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167378839.0x000001&indx=1&recIds=ETOCvdc_100167378839.0x000001

Clinical Characteristics, Cytogenetic Risks, and Prognoses of Young Multiple Myeloma Patients in the Era of Novel Therapies.

Authors: Borst, Nathalie, Ihorst, Gabriele, Wenger, Sina, Räder, Jan, Wäsch, Ralph, Engelhardt, Monika, Rassner, Michael

Source: Cancers; Dec2024, Vol. 16 Issue 23, p4090, 13p

Subject Terms: MULTIPLE myeloma, RISK assessment, HEMATOPOIETIC stem cell transplantation, CANCER patients, AGE distribution, RETROSPECTIVE studies, DESCRIPTIVE statistics, MEDICAL records, ACQUISITION of data, STATISTICS, PROGRESSION-free survival, COMPARATIVE studies, GENETICS, OVERALL survival, DISEASE risk factors, SYMPTOMS

Physical activity and exercise motivation of multiple myeloma patients: a prospective cross-sectional study.

Authors: Räder, Jan, Ihorst, Gabriele, Möller, Mandy-Deborah, Pahl, Antonia, Greil, Christine, Dreyling, Esther, Arends, Jann, Deibert, Peter, Wäsch, Ralph, Engelhardt, Monika

Source: Oncologist; Oct2024, Vol. 29 Issue 10, pe1336-e1346, 11p

Subject Terms: MULTIPLE myeloma, CROSS-sectional method, SELF-evaluation, HEALTH literacy, PATIENT safety, EXERCISE therapy, QUESTIONNAIRES, INTERVIEWING, DESCRIPTIVE statistics, MOTIVATION (Psychology), LONGITUDINAL method, SPORTS participation, PHYSICAL fitness, AEROBIC exercises, QUALITY of life, CANCER patient psychology, PROGRESSION-free survival, PHYSICAL activity, COMORBIDITY, OVERALL survival

Geographic Terms: GERMANY

Company/Entity: WORLD Health Organization

Dapsone-Induced Hemolytic Anemia in Multiple Myeloma: Case Report of Various Differential Diagnoses

Authors: Rassner, Michael, Jung, Johannes, Schneider, Johanna, Wäsch, Ralph, Engelhardt, Monika

Source: Clinical lymphoma, myeloma & leukemia. 20(11):e821-e825

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135108061.0x000001&indx=1&recIds=ETOCvdc_100135108061.0x000001

Risk of disease recurrence and survival in patients with multiple myeloma: A German Study Group analysis using a conditional survival approach with long‐term follow‐up of 815 patients

Authors: Schinke, Maximilian, Ihorst, Gabriele, Duyster, Justus, Wäsch, Ralph, Schumacher, Martin, Engelhardt, Monika

Source: Cancer. 126(15):3504-3515

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122591920.0x000001&indx=1&recIds=ETOCvdc_100122591920.0x000001

Time from first symptom onset to the final diagnosis of multiple myeloma (MM) – possible risks and future solutions: retrospective and prospective 'Deutsche Studiengruppe MM' (DSMM) and 'European Myeloma Network' (EMN) analysis

Authors: Graziani, Giulia, Herget, Georg W., Ihorst, Gabriele, Zeissig, Mara, Chaidos, Aristeidis, Auner, Holger W., Duyster, Justus, Wäsch, Ralph, Engelhardt, Monika

Source: Leukemia & lymphoma. 61(4):875-886

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100431391.0x000001&indx=1&recIds=ETOCvdc_100100431391.0x000001

FDG-PET/CT is a powerful tool to predict and evaluate response to chimeric antigen receptor (CAR) T-cell therapy in Non-Hodgkin-Lymphoma (NHL).

Authors: Wielenberg, Christoph-Ferdinand, Fostitsch, Johannes Christian, Volz, Christian, Marks, Reinhard, Michalski, Kerstin, Wäsch, Ralph, Zeiser, Robert, Ruf, Juri, Meyer, Philipp T., Klein, Claudius

Source: NuclearMedicine / Nuklearmedizin; Aug2024, Vol. 63 Issue 4, p252-258, 7p, 1 Chart, 2 Graphs

Impact of Lung Function on Bronchiolitis Obliterans Syndrome and Outcome after Allogeneic Hematopoietic Cell Transplantation with Reduced-Intensity Conditioning

Authors: Duque-Afonso, Jesús, Ihorst, Gabriele, Waterhouse, Miguel, Zeiser, Robert, Wäsch, Ralph, Bertz, Hartmut, Müller-Quernheim, Joachim, Finke, Jürgen, Marks, Reinhard, Prasse, Antje

Source: In Biology of Blood and Marrow Transplantation November 2018 24(11):2277-2284

Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation

Authors: Sommer, Sebastian, Cruijsen, Marjan, Claus, Rainer, Bertz, Hartmut, Wäsch, Ralph, Marks, Reinhard, Zeiser, Robert, Bogatyreva, Lioudmila, Blijlevens, Nicole M.A., May, Annette, Duyster, Justus, Huls, Gerwin, van der Velden, Walter J.F.M., Finke, Jürgen, Lübbert, Michael

Source: In Leukemia Research September 2018 72:20-26

15-year remission in refractory FLT3-mutated AML attained by sorafenib.

Authors: Rummelt, Christoph, Pfeifer, Dietmar, Wäsch, Ralph, Zeiser, Robert, Duyster, Justus, Finke, Jürgen, Lübbert, Michael

Source: Annals of Hematology; Nov2024, Vol. 103 Issue 11, p4801-4803, 3p

Subject Terms: PROTEIN-tyrosine kinase inhibitors, HEMATOPOIETIC stem cell transplantation, ACUTE myeloid leukemia, MOLECULAR genetics, SORAFENIB, BLAST injuries