Truncated NPY-based NPY(Y1)R-specific radiopeptides: Improved in vivo PET tumor imaging by application of peptidase inhibitors

Authors: Judmann, Benedikt, Baier, Nils F., Rudolf, Henning, Davarci, Güllü, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen

Source: In European Journal of Medicinal Chemistry Reports December 2024 12

Structured reporting of neuroendocrine tumors in PET/CT using [¹⁸F]SiTATE - impact on interdisciplinary communication.

Authors: Hinterberger, Anna, Trupka, Lukas, Kortbein, Sophia, Ebner, Ricarda, Fink, Nicola, Froelich, Matthias F., Nörenberg, Dominik, Wängler, Carmen, Wängler, Björn, Schirrmacher, Ralf, Holzgreve, Adrien, Brendel, Matthias, Corradini, Stefanie, Auernhammer, Christoph, Rübenthaler, Johannes, Grawe, Freba

Source: Scientific Reports; 2/8/2025, Vol. 15 Issue 1, p1-10, 10p

Subject Terms: INTERDISCIPLINARY communication, POSITRON emission tomography, SOMATOSTATIN receptors, NEUROENDOCRINE tumors, PATIENT monitoring

PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide [¹⁸F]SiTATE – first clinical experiences.

Authors: Kunte, Sophie C., Wenter, Vera, Toms, Johannes, Lindner, Simon, Unterrainer, Marcus, Eilsberger, Friederike, Jurkschat, Klaus, Wängler, Carmen, Wängler, Björn, Schirrmacher, Ralf, Tiling, Maximilian W., Sheikh, Gabriel T., Mehrens, Dirk, Brendel, Matthias, Rübenthaler, Johannes, Auernhammer, Christoph J., Spitzweg, Christine, Unterrainer, Lena M., Holzgreve, Adrien

Source: European Journal of Nuclear Medicine & Molecular Imaging; Feb2025, Vol. 52 Issue 3, p900-912, 13p

Subject Terms: MEDULLARY thyroid carcinoma, SOMATOSTATIN receptors, COMPUTED tomography, THYROID cancer, TUMOR markers, CALCITONIN

Ultrasound-Assisted Solid-Phase Affibody Synthesis Using Z EGFR:1907 as an Example—Superior to the Conventional Protocol?

Authors: Prochiner, Marie, Judmann, Benedikt, Ruder, Alina, Wängler, Björn, Schirrmacher, Ralf, Wängler, Carmen

Source: Pharmaceuticals (14248247); Oct2024, Vol. 17 Issue 10, p1280, 11p

Subject Terms: SOLID-phase synthesis, PEPTIDE synthesis, CHEMICAL synthesis, AMINO acids, SONICATION

Automated production of [18F]SiTATE on a Scintomics GRP™ platform for PET/CT imaging of neuroendocrine tumors

Authors: Lindner, Simon, Simmet, Marcel, Gildehaus, Franz Josef, Jurkschat, Klaus, Wängler, Carmen, Wängler, Björn, Bartenstein, Peter, Schirrmacher, Ralf, Ilhan, Harun

Source: In Nuclear Medicine and Biology September-October 2020 88-89:86-95

Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of 68Ga Labeling and Complex Stability Characteristics with Established Chelators

Authors: Damerow, Helen, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen

Source: ChemMedChem. 18(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173145053.0x000001&indx=1&recIds=ETOCvdc_100173145053.0x000001

Contrast enhancement of surface layers with fast middle-infrared scanning

Authors: Kümmel, Tim ^{a, c, ∗}, Teumer, Tobias ^{a, b}, Dörnhofer, Patrick ^a, Methner, Frank-Jürgen ^b, Wängler, Björn ^c, Rädle, Matthias ^a

Source: In Heliyon September 2019 5(9)

Towards Radiolabeled EGFR-Specific Peptides: Alternatives to GE11.

Authors: Judmann, Benedikt^1,2 (AUTHOR), Wängler, Björn² (AUTHOR), Schirrmacher, Ralf³ (AUTHOR), Fricker, Gert⁴ (AUTHOR), Wängler, Carmen¹ (AUTHOR) carmen.waengler@medma.uni-heidelberg.de

Source: Pharmaceuticals (14248247). Feb2023, Vol. 16 Issue 2, p273. 19p.

Subject Terms: *PEPTIDASE, *RADIOACTIVE tracers, *PEPTIDES, *EPIDERMAL growth factor receptors, *CELL receptors, *EPIDERMAL growth factor, *RADIOCHEMICAL purification

Functional Hybrid Molecules for the Visualization of Cancer: PESIN‐Homodimers Combined with Multimodal Molecular Imaging Probes for Positron Emission Tomography and Optical Imaging: Suited for Tracking of GRPR‐Positive Malignant Tissue**

Authors: Hübner, Ralph, Cheng, Xia, Wängler, Björn, Wängler, Carmen

Source: Chemistry. 26(69):16349-16356

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115392809.0x000001&indx=1&recIds=ETOCvdc_100115392809.0x000001

Synthesis, characterization and optimization of in vitro properties of NIR-fluorescent cyclic α-MSH peptides for melanoma imagingElectronic supplementary information (ESI) available. See DOI: 10.1039/d0tb01798a

Authors: von Kiedrowski, Valeska, Hübner, Ralph, Kail, Dagmar, Cheng, Xia, Schirrmacher, Ralf, Wängler, Carmen, Wängler, Björn

Source: Journal of materials chemistry.B. 8(46):10602-10608

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111607660.0x000001&indx=1&recIds=ETOCvdc_100111607660.0x000001

Probing two PESIN-indocyanine-dye-conjugates: significance of the used fluorophoreElectronic supplementary information (ESI) available. See DOI: 10.1039/c9tb01794a

Authors: Hübner, Ralph, Benkert, Vanessa, Cheng, Xia, Wängler, Björn, Krämer, Roland, Wängler, Carmen

Source: Journal of materials chemistry.B. 8(6):1302-1309

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098713666.0x000001&indx=1&recIds=ETOCvdc_100098713666.0x000001

Performance assessment of the ALBIRA II pre-clinical SPECT S102 system for 99mTc imaging

Authors: Attarwala, Ali Asgar, Hardiansyah, Deni, Romanó, Chiara, Jiménez-Franco, Luis David, Roscher, Mareike, Wängler, Björn, Glatting, Gerhard

Source: Annals of nuclear medicine. 35(1):111-120

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191106569.0x000001&indx=1&recIds=ETOCvdc_100191106569.0x000001

Tropomyosin receptor kinase inhibitors: an updated patent review for 2016–2019

Authors: Bailey, Justin J., Jaworski, Carolin, Tung, Donovan, Wängler, Carmen, Wängler, Björn, Schirrmacher, Ralf

Source: Expert opinion on therapeutic patents. 30(5):325-339

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110710257.0x000001&indx=1&recIds=ETOCvdc_100110710257.0x000001

Identification of a Suitable Peptidic Molecular Platform for the Development of NPY(Y1)R‐Specific Imaging Agents

Authors: Krieger, Korbinian, Wängler, Björn, Schirrmacher, Ralf, Wängler, Carmen

Source: ChemMedChem. 15(17):1652-1660

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108102996.0x000001&indx=1&recIds=ETOCvdc_100108102996.0x000001

Design, synthesis and in vitro evaluation of heterobivalent peptidic radioligands targeting both GRP- and VPAC1-Receptors concomitantly overexpressed on various malignancies – Is the concept feasible?

Authors: Lindner, Simon, Fiedler, Luise, Wängler, Björn, Bartenstein, Peter, Schirrmacher, Ralf, Wängler, Carmen

Source: In European Journal of Medicinal Chemistry 15 July 2018 155:84-95

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors

Authors: Prause, Martin, Niedermoser, Sabrina, Wängler, Carmen, Decristoforo, Clemens, Seibold, Uwe, Riester, Stephanie, Taguchi, Takahiro, Schirrmacher, Ralf, Fricker, Gert, Wängler, Björn

Source: In Nuclear Medicine and Biology February 2018 57:1-11

Targeted 64Cu‐labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging

Authors: Pretze, Marc, Meulen, Nick P., Wängler, Carmen, Schibli, Roger, Wängler, Björn

Source: Journal of labelled compounds & radiopharmaceuticals. 62(8):471-482

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085099733.0x000001&indx=1&recIds=ETOCvdc_100085099733.0x000001

The Exception That Proves the Rule: How Sodium Chelation Can Alter the Charge‐Cell Binding Correlation of Fluorescein‐Based Multimodal Imaging Agents

Authors: Maspero, Marco, Dallanoce, Clelia, Wängler, Björn, Wängler, Carmen, Hübner, Ralph

Source: ChemMedChem. 17(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147749623.0x000001&indx=1&recIds=ETOCvdc_100147749623.0x000001

Small Prosthetic Groups in 18F-Radiochemistry: Useful Auxiliaries for the Design of 18F-PET Tracers

Authors: Schirrmacher, Ralf ^{*, *}, Wängler, Björn, Bailey, Justin ^*, Bernard-Gauthier, Vadim ^*, Schirrmacher, Esther ^*, Wängler, Carmen

Source: In Seminars in Nuclear Medicine September 2017 47(5):474-492

Investigation of the imaging characteristics of the ALBIRA II small animal PET system for 18F, 68Ga and 64Cu

Alternate Title: Untersuchung der bildgebenden Eigenschaften des ALBIRA II Kleintier-PET-Systems für 18F, 68Ga und 64Cu (German)

Authors: Attarwala, Ali Asgar, Karanja, Yvonne Wanjiku, Hardiansyah, Deni, Romanó, Chiara, Roscher, Mareike, Wängler, Björn, Glatting, Gerhard

Source: In Zeitschrift fuer Medizinische Physik June 2017 27(2):132-144