Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations.

Authors: Cullot, Grégoire¹ (AUTHOR) gregoire.cullot@biol.ethz.ch, Aird, Eric J. (AUTHOR), Schlapansky, Moritz F. (AUTHOR), Yeh, Charles D. (AUTHOR), van de Venn, Lilly (AUTHOR), Vykhlyantseva, Iryna (AUTHOR), Kreutzer, Susanne (AUTHOR), Mailänder, Dominic (AUTHOR), Lewków, Bohdan (AUTHOR), Klermund, Julia^2,3 (AUTHOR), Montellese, Christian^4,5 (AUTHOR), Biserni, Martina^4,5 (AUTHOR), Aeschimann, Florian^4,5 (AUTHOR), Vonarburg, Cédric^4,5 (AUTHOR), Gehart, Helmuth (AUTHOR), Cathomen, Toni^2,3 (AUTHOR), Corn, Jacob E.¹ (AUTHOR) jacob.corn@biol.ethz.ch

Source: Nature Biotechnology. Nov2024, p1-5.

Subject Terms: *CHROMOSOMES