Proton therapy induces a local microglial neuroimmune response

Authors: Voshart, Daniëlle C., Klaver, Myrthe, Jiang, Yuting, van Weering, Hilmar R.J., van Buuren-Broek, Fleur, van der Linden, Gideon P., Cinat, Davide, Kiewiet, Harry H., Malimban, Justin, Vazquez-Matias, Daniel A., Reali Nazario, Luiza, Scholma, Ayla C., Sewdihal, Jeffrey, van Goethem, Marc-Jan, van Luijk, Peter, Coppes, Rob P., Barazzuol, Lara

Source: In Radiotherapy and Oncology April 2024 193

Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state

Authors: Voshart, Daniëlle C., Oshima, Takuya, Jiang, Yuting, van der Linden, Gideon P., Ainslie, Anna P., Reali Nazario, Luiza, van Buuren-Broek, Fleur, Scholma, Ayla C., van Weering, Hilmar R.J., Brouwer, Nieske, Sewdihal, Jeffrey, Brouwer, Uilke, Coppes, Rob P., Holtman, Inge R., Eggen, Bart J.L., Kooistra, Susanne M., Barazzuol, Lara

Source: In Cell Reports 27 February 2024 43(2)

Glioblastoma and its treatment are associated with extensive accelerated brain aging.

Authors: Ainslie, Anna P., Klaver, Myrthe, Voshart, Daniëlle C., Gerrits, Emma, den Dunnen, Wilfred F. A., Eggen, Bart J. L., Bergink, Steven, Barazzuol, Lara

Source: Aging Cell; Mar2024, Vol. 23 Issue 3, p1-14, 14p

Subject Terms: METHYLGUANINE, DNA damage, GLIOBLASTOMA multiforme, AGING, BRAIN tumors, ALZHEIMER'S disease, TAU proteins

Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer's Disease Leads to Neuroglial and Endothelial Cell Degeneration.

Authors: Villar-Vesga, Juan, Henao-Restrepo, Julián, Voshart, Daniëlle C., Aguillon, David, Villegas, Andrés, Castaño, Diana, Arias-Londoño, Julián D., Zuhorn, Inge S., Ribovski, Laís, Barazzuol, Lara, Cardona-Gómez, Gloria P., Posada-Duque, Rafael

Source: Frontiers in Aging Neuroscience; 11/10/2020, Vol. 12, pN.PAG-N.PAG, 22p

Subject Terms: EXTRACELLULAR vesicles, CELL death, ALZHEIMER'S disease, ENDOTHELIAL cells, BIOMARKERS

Regional Responses in Radiation-Induced Normal Tissue Damage.

Authors: Voshart, Daniëlle C.^1,2 (AUTHOR) d.c.voshart@umcg.nl, Wiedemann, Julia^1,2 (AUTHOR) j.wiedemann@umcg.nl, van Luijk, Peter^1,2 (AUTHOR) p.van.luijk@umcg.nl, Barazzuol, Lara^1,2 (AUTHOR) p.van.luijk@umcg.nl, Wong, David (AUTHOR)

Source: Cancers. Feb2021, Vol. 13 Issue 3, p367. 1p.

Subject Terms: *BLADDER, *HUMAN body, *BRAIN, *HEART, *LUNGS, *PANCREAS, *RADIATION doses, *RADIATION protection, *RADIATION injuries, *RADIOTHERAPY, *SALIVARY glands