Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease

Authors: Hatten, Hannes ^{a, 1}, Colyn, Leticia ^{a, ⁎, 1}, Volkert, Ines ^a, Gaßler, Nikolaus ^b, Lammers, Twan ^c, Hofmann, Ute ^{d, e}, Hengstler, Jan G. ^f, Schneider, Kai Markus ^a, Trautwein, Christian ^{a, f, ⁎⁎}

Source: In BBA - Molecular Basis of Disease October 2024 1870(7)

Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA.

Authors: Lin, Cheng^1,2, Kuzmanović, Adrian¹, Wang, Nan^1,3, Liao, Liangliang^1,4, Ernst, Sabrina⁵, Penners, Christian¹, Jans, Alexander¹, Hammoor, Thomas^6,7, Stach, Petra Bumnuri¹, Peltzer, Mona¹, Volkert, Ines¹, Zechendorf, Elisabeth⁸, Hassan, Reham^9,10, Myllys, Maiju⁹, Liedtke, Christian¹, Herrmann, Andreas^6,7, Chakraborty, Gurudas⁶, Trautwein, Christian⁹, Hengstler, Jan⁹, Müller‐Newen, Gerhard¹¹

Source: Advanced Science; 3/6/2025, Vol. 12 Issue 9, p1-17, 17p

Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression.

Authors: Volkert, Ines, Fromme, Malin, Schneider, Carolin, Candels, Lena, Lindhauer, Cecilia, Su, Huan, Thorhauge, Katrine, Pons, Monica, Mohamed, Mohamed Ramadan, Schneider, Kai Markus, Strnad, Pavel, Trautwein, Christian

Source: Hepatology (02709139); Apr2024, Vol. 79 Issue 4, p898-911, 14p

PNPLA3 I148M polymorphism does not promote liver disease progression in severe alpha1-antitrypsin deficiency

Authors: Volkert, Ines, Fromme, Malin, Su, Huan, Gueldiken, Nurdan, Mohamed, Mohamed Ramadan, Lindhauer, Cecilia, Strnad, Pavel, Trautwein, Christian

Source: Journal of hepatology. 78(S1):S639-S639

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195504035.0x000001&indx=1&recIds=ETOCvdc_100195504035.0x000001

Caspase 8 reverses progression of NASH after hepatocyte-specific JNK deletion

Authors: Volkert, Ines, Piche, Julia, Trautwein, Christian

Source: Journal of hepatology. 78(S1):S730-S730

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195503260.0x000001&indx=1&recIds=ETOCvdc_100195503260.0x000001

Hepatocyte-specific JNK signaling is protective during progression of NASH

Authors: Piche, Julia, Volkert, Ines, Woitok, Marius Maximilian, Otto, Tobias, Trautwein, Christian

Source: Journal of hepatology. 77(S1):S729-S729

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167266005.0x000001&indx=1&recIds=ETOCvdc_100167266005.0x000001

FRI-522 Loss of Toll-like receptor 9 protects from hepatocellular carcinoma in murine models of chronic liver disease

Authors: Hatten, Hannes, Colyn, Leticia, Volkert, Ines, Lammers, Twan, Schneider, Kai Markus, Trautwein, Christian

Source: In Journal of Hepatology June 2024 80 Supplement 1:S431-S431

WED-521-YI Tissue-specific roles of Farnesoid X Receptor in gut-liver axis and influence on progressive cholestatic liver injury

Authors: Ludwigs, Lina, Volkert, Ines, Peltzer, Mona, Molinaro, Antonio, Henricsson, Marcus, Marschall, Hanns-Ulrich, Edlund, Karolina, Markus Schneider, Kai, Longerich, Thomas, Boor, Peter, G. Hengstler, Jan, Trautwein, Christian, Susanna Candels, Lena

Source: In Journal of Hepatology June 2024 80 Supplement 1:S273-S274

OS-088-YI Selective ablation of Caspase 8 in hepatocytes ameliorates development of metabolic dysfunction-associated steatohepatitis following hepatocyte-specific JNK deletion

Authors: Volkert, Ines, Grube, Julia, Edlund, Karolina, Duda, Julia, Guillot, Adrien, Berger, Hilmar, Rahnenführer, Jörg, Tacke, Frank, Hengstler, Jan G., Trautwein, Christian

Source: In Journal of Hepatology June 2024 80 Supplement 1:S57-S57

TOP-084 - Caspase 8 reverses progression of NASH after hepatocyte-specific JNK deletion

Authors: Volkert, Ines, Piche, Julia, Trautwein, Christian

Source: In Journal of Hepatology June 2023 78 Supplement 1:S730-S730

THU-472 - PNPLA3 I148M polymorphism does not promote liver disease progression in severe alpha1-antitrypsin deficiency

Authors: Volkert, Ines, Fromme, Malin, Su, Huan, Gueldiken, Nurdan, Mohamed, Mohamed Ramadan, Lindhauer, Cecilia, Strnad, Pavel, Trautwein, Christian

Source: In Journal of Hepatology June 2023 78 Supplement 1:S639-S639

SAT137 - Hepatocyte-specific JNK signaling is protective during progression of NASH

Authors: Piche, Julia, Volkert, Ines, Woitok, Marius Maximilian, Otto, Tobias, Trautwein, Christian

Source: In Journal of Hepatology July 2022 77 Supplement 1:S729-S729

Hyperammonemia induces programmed liver cell death.

Authors: Kerbert, Annarein J. C.^1,2 j.ckerbert@lumc.nl, Engelmann, Cornelius^1,3, Habtesion, Abeba¹, Kumar, Pavitra³, Hassan, Mohsin^3,4, Tingting Qi^1,5, Volkert, Ines⁶, Otto, Tobias⁶, Hall, Andrew^7,8, Khetan, Varun U.¹, Damink, Steven Olde⁹, Aguilar, Ferran¹⁰, Chollet, Céline¹¹, Brunet, Ludovic¹¹, Clària, Joan^10,12, Moreau, Richard^10,13,14, Arroyo, Vicente¹⁰, Coenraad, Minneke J.², Mehta, Gautam^1,15, Castelli, Florence¹¹

Source: Science Advances. 3/7/2025, Vol. 11 Issue 10, p1-17. 17p.