Role of Inflammation and Motility Disorders in the Development, Course and Consequences of Functional Gastrointestinal and Biliary Tract Diseases (Literature Review and Expert Panel Resolution)

Authors: V. T. Ivashkin, D. S. Bordin, T. L. Lapina, M. A. Livzan, A. V. Okhlobystin, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspenskiy, Yu. O. Shulpekova

Source: Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 34, Iss 4, Pp 7-19 (2024)

Subject Terms: functional gastrointestinal diseases, functional biliary tract diseases, low-grade inflammation, visceral hypersensitivity, motility, cytokines, trimebutine, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://www.gastro-j.ru/jour/article/view/1347; https://doaj.org/toc/1382-4376; https://doaj.org/toc/2658-6673

Access URL: https://doaj.org/article/b4f8a49670c84cf494b3a0b7cc78d4d6

The long road to diagnosis, from gastroesophageal reflux disease, through Barrett's esophagus, to visceral hypersensitivity: a case report

Authors: Małgorzata Wirkijowska, Jolanta Mędyk, Yauheniya Patarocha, Michał Rogulski, Aleksandra Ślusarska, Paulina Błasiak, Patryk Mikołajec, Ruslan Huk, Barbara Bilecka, Jakub Wirkijowski

Source: Journal of Education, Health and Sport, Vol 77 (2025)

Subject Terms: visceral hypersensitivity, case report, gastroesophageal reflux disease, irritable bowel syndrome, therapy, small intestine bacterial overgrowth, Education, Sports, GV557-1198.995, Medicine

File Description: electronic resource

Relation: https://apcz.umk.pl/JEHS/article/view/57199; https://doaj.org/toc/2391-8306

Access URL: https://doaj.org/article/d9a0bc78cfc5424b8cd28ba503e51a73

Toll-like receptor 4 plays a vital role in irritable bowel syndrome: a scoping review

Authors: Xuemeng Wan, Liyuan Wang, Zhiling Wang, Chaomin Wan

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: irritable bowel syndrome, toll-like receptor 4, inflammation, visceral hypersensitivity, treatment, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1490653/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/350db2bf486d4a798ce526e731c0f48a

Impact of electro-acupuncture on EAAT2 and NMDAR-2B expression in goats with visceral hypersensitivity

Authors: Adnan Hassan Tahir, Yi Ding, Juan Wan, Manoj Kumar Shah, Habibullah Janyaro, Xiao-Jing Li, Ming-Xing Ding

Source: Heliyon, Vol 10, Iss 23, Pp e40700- (2024)

Subject Terms: Electro-acupuncture, Inflammatory bowel disease, Ileitis, TNBS, Visceral hypersensitivity, NMDAR-2B, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S240584402416731X; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/2d11c51318c74d47b6a659fb9e8fa80c

Spinal astrocyte-derived M-CSF mediates microglial reaction and drives visceral hypersensitivity following DSS-induced colitis

Authors: Wu, Ke ^{a, d, 1}, Shao, Shuai ^{a, b, c, 1}, Dong, Yu-ting ^{a, b, c}, Liu, Yue-ying ^{a, b, c}, Chen, Xing-han ^{a, b, c}, Cheng, Peng ^{a, b, c}, Qin, Xia ^{a, b, c}, Peng, Xiao-han ^{a, e}, Zhang, Yong-mei ^{a, b, c, ⁎}

Source: In Neuropharmacology 1 June 2025 270

The Role and the Regulation of NLRP3 Inflammasome in Irritable Bowel Syndrome: A Narrative Review

Authors: Arezina Kasti, Konstantinos Katsas, Maroulla D. Nikolaki, Konstantinos Triantafyllou

Source: Microorganisms, Vol 13, Iss 1, p 171 (2025)

Subject Terms: irritable bowel syndrome, NLRP3 inflammasome, visceral hypersensitivity, proinflammatory cytokines, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/13/1/171; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/0a6f9a5218ef4e1696422072e0970377

Gastrointestinal pathophysiology in long COVID: Exploring roles of microbiota dysbiosis and serotonin dysregulation in post-infectious bowel symptoms

Authors: Yu, Linda Chia-Hui ^⁎

Source: In Life Sciences 1 December 2024 358

Acupuncture and moxibustion intervention in functional dyspepsia: Gastric and duodenal regulation

Authors: Hongxiu Chen, Min He, Jiazhen Cao, Yifan Zhang, Ying Zhou, Qianhui Yu, Anjie Wang, Jing Xuan, Tie Li

Source: Heliyon, Vol 10, Iss 17, Pp e35696- (2024)

Subject Terms: Functional dyspepsia, Acupuncture and moxibustion, Gastrointestinal dysfunction, Low-grade inflammation of the duodenum, Visceral hypersensitivity, Duodenal intestinal barrier, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024117276; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/c70b8afb4626402081a60dea4243cbd1

Butyrate promotes visceral hypersensitivity in IBS model via mast cell-derived DRG neuron lincRNA-01028-PKC-TRPV1 pathway

Authors: Ying-Jie Li, Jing Li, Cong Dai

Source: mBio, Vol 15, Iss 8 (2024)

Subject Terms: visceral hypersensitivity, butyrate, short-chain fatty acids, dorsal root ganglion, mast cell, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/ee41893115b346ab833f7de51aa274d8

Identification of Arginine-Vasopressin Receptor 1a (Avpr1a/Avpr1a) as a Novel Candidate Gene for Chronic Visceral Pain Sheds Light on the Potential Role of Enteric Neurons in the Development of Visceral Hypersensitivity

Authors: Kader, Leena ^{⁎, †}, Willits, Adam B. ^{⁎, †}, Meriano, Sebastian ^{⁎, ‡}, Christianson, Julie A. ^‡, La, Jun-Ho ^§, Feng, Bin ^¶, Knight, Brittany ^∥, Kosova, Gulum ^⁎⁎, Deberry, Jennifer J. ^††, Coates, Matthew D. ^‡‡, Hyams, Jeffrey S. ^§§, Baumbauer, Kyle M. ^{⁎, ‡}, Young, Erin E. ^{⁎, †, ‡, ⁎}

Source: In The Journal of Pain September 2024 25(9)

Gut–Brain Axis, Microbiota and Probiotics—Current Knowledge on Their Role in Irritable Bowel Syndrome: A Review

Authors: Cristina Maria Marginean, Mihaela Popescu, Andrei Ioan Drocas, Sergiu Marian Cazacu, Radu Mitrut, Iulia Cristina Marginean, George Alexandru Iacob, Marian Sorin Popescu, Anca Oana Docea, Paul Mitrut

Source: Gastrointestinal Disorders, Vol 5, Iss 4, Pp 517-535 (2023)

Subject Terms: irritable bowel syndrome, gut–brain axis, gut microbiota, inflammation, visceral hypersensitivity, probiotics, Medicine, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://www.mdpi.com/2624-5647/5/4/43; https://doaj.org/toc/2624-5647

Access URL: https://doaj.org/article/ef108a87a05246c283d12637ee07a736

Long-term probiotic administration for irritable bowel syndrome: a legal need

Authors: Olga I. Solovyeva, Anna S. Nekrasova, Iulia G. Topalova, Viktoriia A. Ponomarenko, Daredzhan B. Tsurtsumiia, Inna G. Ilyashevich

Source: Терапевтический архив, Vol 95, Iss 8, Pp 679-685 (2023)

Subject Terms: ibs, irritable bowel syndrome, probiotics, bifidobacterium longum 35624®, quality of life, visceral hypersensitivity, ibs-qol, ibs-sss, vas-ibs, prolonged course, anti-relapse course, Medicine

File Description: electronic resource

Relation: https://ter-arkhiv.ru/0040-3660/article/viewFile/607418/136058; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342

Access URL: https://doaj.org/article/998adbbd0bfa42b49d87b3566b683090

Drug therapy’s new options in the treatment of the severe irritable bowel syndrome

Authors: Alina A. Makarova, Irina N. Ruchkina, Galina M. Diukova, Nataliy V. Romashkina, Lilia Kh. Indejkina, Daniil A. Degterev, Asfold I. Parfenov

Source: Терапевтический архив, Vol 95, Iss 8, Pp 627-633 (2023)

Subject Terms: ibs-d, visceral hypersensitivity, balloon dilation test, ibs extraintestinal manifestations, overlap syndrome, Medicine

File Description: electronic resource

Relation: https://ter-arkhiv.ru/0040-3660/article/viewFile/607399/136046; https://doaj.org/toc/0040-3660; https://doaj.org/toc/2309-5342

Access URL: https://doaj.org/article/745916310d1547d18bf0c4940a40db5e

Patients with postprandial distress syndrome experience problems with their interoceptive perceptual function to the gastric region, but their heartbeat perception is normal: a case control study

Authors: Kohei Yoshida, Tetsuya Abe, Kenji Kanbara, Kento Ueda, Yukie Saka-Kouchi, Hideaki Hasuo

Source: BioPsychoSocial Medicine, Vol 17, Iss 1, Pp 1-8 (2023)

Subject Terms: Postprandial distress syndrome, Interoceptive accuracy, Heartbeat tracking task, Five-minute water load test, Visceral hypersensitivity, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/1751-0759

Access URL: https://doaj.org/article/2d1c3b77e5804d538f40e9d124f72d70

How Tongxie-Yaofang Regulates Intestinal Synaptic Plasticity by Activating Enteric Glial Cells and NGF/TrkA Pathway in Diarrhea-Predominant Irritable Bowel Syndrome Rats

Authors: Lu X, Zhang S

Source: Drug Design, Development and Therapy, Vol Volume 17, Pp 2969-2983 (2023)

Subject Terms: diarrhea-predominant irritable bowel syndrome, tongxie-yaofang, visceral hypersensitivity, synaptic plasticity, enteric glial cell, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/how-tongxie-yaofang-regulates-intestinal-synaptic-plasticity-by-activa-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/6fde8cbbbc0e445db13e5f0eb0ba395e

Tryptase activates enteric glial cells followed by affecting neuronal properties possibly via the stimuli-associated mediators

Authors: Kazunari Tominaga, Yoshiko Fujikawa

Source: Journal of Pharmacological Sciences, Vol 151, Iss 4, Pp 163-170 (2023)

Subject Terms: Visceral hypersensitivity, Irritable bowel syndrome, Enteric glial cell, Nerve growth factor, Neuronal elongation factors, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861323000063; https://doaj.org/toc/1347-8613

Access URL: https://doaj.org/article/4a815657e03246e38d0238b1c0463589

Characteristics of gut microbiota in male periadolescent rats with irritable bowel syndrome

Authors: Lin, Wei ^{a, 1}, Wu, Dongxiao ^{b, 1}, Zeng, Yongbin ^{c, d}, Liu, Yuan ^e, Yu, Dajie ^a, Wei, Jianhang ^a, Cai, Yanliang ^a, Lin, Yueli ^a, Wu, Bin ^{a, ∗∗}, Huang, Huanhuan ^{a, ∗}

Source: In Heliyon August 2023 9(8)

Maternal separation and TNBS-induced gut inflammation synergistically alter the sexually differentiated stress response in rats

Authors: Ryoko Hasegawa, Kumi Saito-Nakaya, Li Gu, Motoyori Kanazawa, Shin Fukudo

Source: BioPsychoSocial Medicine, Vol 17, Iss 1, Pp 1-12 (2023)

Subject Terms: Attention-deficit/hyperactivity disorder, Corticotropin-releasing hormone, Early-life stress, Irritable bowel syndrome, Maternal separation, Visceral hypersensitivity, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/1751-0759

Access URL: https://doaj.org/article/ba0f3fd170c24815aca843f939ffec98

Efficacies of Tong-Xie-Yao-Fang Disassembled Recipes on Brain-gut Peptideina Rat Model of Diarrhea-predominant Irritable Bowel Syndrome

Authors: WANG Kekai, YANG Yanlin, ZHOU Yanni, XIAO Jin, XIE Xin, WU Qinping, CHEN Min

Source: Zhongguo quanke yixue, Vol 26, Iss 05, Pp 569-575 (2023)

Subject Terms: irritable bowel syndrome, diarrheatype irritable bowel syndrome, tong-xie-yao-fang, drugs, chinese herbal, visceral hypersensitivity, brain-derived neurotrophic factor, substance p, Medicine

File Description: electronic resource

Relation: https://www.chinagp.net/fileup/1007-9572/PDF/zx20220510.pdf; https://doaj.org/toc/1007-9572

Access URL: https://doaj.org/article/a6b74d91e5a34078a4db03d2be9de794

Spirocyclopiperazinium salt compound DXL-A-24 improves visceral sensation and gut microbiota in a rat model of irritable bowel syndrome

Authors: Xu, Yan ¹, Yao, Ru ¹, Zhao, Wenxue, Zhu, Jianguo, Yao, Jingchun, Zhang, Guimin, Liu, Dongguang ^∗

Source: In Heliyon June 2023 9(6)