Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies

Authors: Garcia-Prieto, Carlos A, Villanueva, Lorea, Bueno-Costa, Alberto, Davalos, Veronica, González-Navarro, Europa Azucena, Juan, Manel, Urbano-Ispizua, Álvaro, Delgado, Julio, Ortiz-Maldonado, Valentín, del Bufalo, Francesca, Locatelli, Franco, Quintarelli, Concetta, Sinibaldi, Matilde, Soler, Marta, Castro de Moura, Manuel, Ferrer, Gerardo, Urdinguio, Rocio G, Fernandez, Agustin F, Fraga, Mario F, Bar, Diana, Meir, Amilia, Itzhaki, Orit, Besser, Michal J, Avigdor, Abraham, Jacoby, Elad, Esteller, Manel

Source: Journal of the National Cancer Institute. 114(3):436-445

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144309116.0x000001&indx=1&recIds=ETOCvdc_100144309116.0x000001

Oncolytic viruses: A new immunotherapeutic approach for breast cancer treatment?

Authors: Cejalvo, Juan Miguel, Falato, Claudette, Villanueva, Lorea, Tolosa, Pablo, González, Xavier, Pascal, Mariona, Canes, Jordi, Gavilá, Joaquín, Manso, Luis, Pascual, Tomás, Prat, Aleix, Salvador, Fernando

Source: In Cancer Treatment Reviews May 2022 106

Addition of immune checkpoint inhibitors to chemotherapy versus chemotherapy alone in first-line metastatic triple-negative breast cancer: A systematic review and meta-analysis

Authors: Villacampa, Guillermo, Tolosa, Pablo, Salvador, Fernando, Sánchez-Bayona, Rodrigo, Villanueva, Lorea, Dienstmann, Rodrigo, Ciruelos, Eva, Pascual, Tomas

Source: In Cancer Treatment Reviews March 2022 104

Palbociclib and letrozole for hormone receptor-positive HER2-negative breast cancer with residual disease after neoadjuvant chemotherapy.

Authors: Pernas, Sonia, Sanfeliu, Esther, Villacampa, Guillermo, Salvador, Javier, Perelló, Antonia, González, Xavier, Jiménez, Begoña, Merino, María, Palacios, Patricia, Pascual, Tomás, Alba, Emilio, Villanueva, Lorea, Chillara, Samyukta, Ferrero-Cafiero, Juan Manuel, Galvan, Patricia, Prat, Aleix, Ciruelos, Eva

Source: NPJ Breast Cancer; 11/26/2024, Vol. 10 Issue 1, p1-8, 8p

The Contribution of Epigenetics to Cancer Immunotherapy

Authors: Villanueva, Lorea, Álvarez-Errico, Damiana, Esteller, Manel

Source: In Trends in Immunology August 2020 41(8):676-691

Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model

Authors: Llopiz, Diana, Ruiz, Marta, Villanueva, Lorea, Iglesias, Tamara, Silva, Leyre, Egea, Josune, Lasarte, Juan J., Pivette, Perrine, Trochon-Joseph, Véronique, Vasseur, Bérangère, Dixon, Graham, Sangro, Bruno, Sarobe, Pablo

Source: Cancer immunology, immunotherapy. 68(3):379-393

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167890901.0x000001&indx=1&recIds=ETOCvdc_100167890901.0x000001

Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model

Authors: Llopiz, Diana, Ruiz, Marta, Villanueva, Lorea, Iglesias, Tamara, Silva, Leyre, Egea, Josune, Lasarte, Juan J., Pivette, Perrine, Trochon-Joseph, Véronique, Vasseur, Bérangère, Dixon, Graham, Sangro, Bruno, Sarobe, Pablo

Source: Cancer immunology, immunotherapy. 68(3):379-393

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125514989.0x000001&indx=1&recIds=ETOCvdc_100125514989.0x000001

Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection

Authors: Zabaleta, Aintzane, D'Avola, Delia, Echeverria, Itziar, Llopiz, Diana, Silva, Leyre, Villanueva, Lorea, Riezu-Boj, José Ignacio, Larrea, Esther, Pereboev, Alexander, Lasarte, Juan José, Rodriguez-Lago, Iago, Iñarrairaegui, Mercedes, Sangro, Bruno, Prieto, Jesús, Sarobe, Pablo

Source: In Molecular Therapy - Methods & Clinical Development 2015 2

PVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma

Authors: Martinez-Verbo, Laura, Veselinova, Yoana, Llinàs-Arias, Pere, García-Prieto, Carlos A., Noguera-Castells, Aleix, Pato, Miguel L., Bueno-Costa, Alberto, Campillo-Marcos, Ignacio, Villanueva, Lorea, Oliver-Caldes, Aina, Cardus, Oriol, Salsench, Sergi V., García-Ortiz, Almudena, Valeri, Antonio, Rojas, Elizabeta A., Barrena, Naroa, Gutiérrez, Norma C., Prósper, Felipe, Agirre, Xabier, Fernández de Larrea, Carlos, Martínez-López, Joaquín, Ferrer, Gerardo, Esteller, Manel

Source: Leukemia; 20240101, Issue: Preprints p1-5, 5p

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation

Authors: Lozano, Teresa, Villanueva, Lorea, Durántez, Maika, Gorraiz, Marta, Ruiz, Marta, Belsúe, Virginia, Riezu-Boj, José I., Hervás-Stubbs, Sandra, Oyarzábal, Julen, Bandukwala, Hozefa

Source: Journal of immunology. 195(7):3180-3189

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN602893697&indx=1&recIds=ETOCRN602893697

Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses

Authors: Rudilla, Francesc, Fayolle, Catherine, Casares, Noelia, Durantez, Maika, Arribillaga, Laura, Lozano, Teresa, Villanueva, Lorea, Pio, Ruben, Sarobe, Pablo, Leclerc, Claude, Prieto, Jesús, Lasarte, Juan José

Source: In Vaccine 16 April 2012 30(18):2848-2858

The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer

Authors: Villanueva, Lorea, Silva, Leyre, Llopiz, Diana, Ruiz, Marta, Iglesias, Tamara, Lozano, Teresa, Casares, Noelia, Hervas-Stubbs, Sandra, Rodríguez, María José, Carrascosa, José L., Lasarte, Juan José, Sarobe, Pablo

Source: Oncoimmunology. 7(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100071858027.0x000001&indx=1&recIds=ETOCvdc_100071858027.0x000001

CD155 on Multiple Myeloma Cells Is Epigenetically Regulated, Reduce Patients Survival and Compromises the Action of Novel Immunotherapies

Authors: Martinez-Verbo, Laura, Villanueva, Lorea, Llinàs-Arias, Pere, García-Prieto, Carlos Antonio, Piñeyro, David, Oliver-Caldes, Aina, García-Ortiz, Almudena, Valeri, Antonio, Fernández de Larrea, Carlos, Martinez-Lopez, Joaquin, Ferrer, Gerardo, Esteller, Manel

Source: In Blood 2 November 2023 142 Supplement 1:6567-6567

DNA methylation-associated dysregulation of transfer RNA expression in human cancer.

Authors: Rosselló-Tortella, Margalida, Bueno-Costa, Alberto, Martínez-Verbo, Laura, Villanueva, Lorea, Esteller, Manel

Source: Molecular Cancer; 2/12/2022, Vol. 21 Issue 1, p1-8, 8p

Subject Terms: TRANSFER RNA, DNA, RENAL cell carcinoma, MOLECULAR biology, RNA polymerase II, RNA regulation, CANCER cell growth

P822: EPIGENETIC REGULATION OF CD155 ON MULTIPLE MYELOMA CELLS INFLUENCES ANTI‐TUMOR NOVEL IMMUNOTHERAPEUTIC APPROACHES.

Authors: Martinez‐Verbo, Laura, Villanueva, Lorea, Llinàs‐Arias, Pere, Antonio García‐Prieto, Carlos, Piñeyro, David, Oliver‐Caldes, Aina, García‐Ortiz, Almudena, Valeri, Antonio, De Larrea, Carlos Fernández, Martínez‐López, Joaquin, Ferrer, Gerardo, Esteller, Manel

Source: HemaSphere; 2023 Supplement 3, Vol. 7, p1-2, 2p

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Cold-Inducible RNA Binding Protein as a Vaccination Platform to Enhance Immunotherapeutic Responses against Hepatocellular Carcinoma.

Authors: Silva, Leyre, Egea, Josune, Villanueva, Lorea, Ruiz, Marta, Llopiz, Diana, Repáraz, David, Aparicio, Belén, Lasarte-Cia, Aritz, Lasarte, Juan José, Ruiz de Galarreta, Marina, Lujambio, Amaia, Sangro, Bruno, Sarobe, Pablo

Source: Cancers; Nov2020, Vol. 12 Issue 11, p3397, 1p

Subject Terms: PROTEIN metabolism, ANIMAL experimentation, ANIMALS, EXPERIMENTAL design, HEPATOCELLULAR carcinoma, IMMUNIZATION, IMMUNOTHERAPY, MICE, PHENOTYPES, RNA-binding proteins, IMMUNE checkpoint inhibitors, THERAPEUTICS