The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection

Authors: Fernández, Jose Javier, Marín, Arturo, Rosales, Romel, Penrice-Randal, Rebekah, Mlcochova, Petra, Alvarez, Yolanda, Villalón-Letelier, Fernando, Yildiz, Soner, Pérez, Enrique, Rathnasinghe, Raveen, Cupic, Anastasija, Kehrer, Thomas, Uccellini, Melissa B., Alonso, Sara, Martínez, Fernando, McGovern, Briana Lynn, Clark, Jordan J., Sharma, Parul, Bayón, Yolanda, Alonso, Andrés, Albrecht, Randy A., White, Kris M., Schotsaert, Michael, Miorin, Lisa, Stewart, James P., Hiscox, Julian A., Gupta, Ravindra K., Irigoyen, Nerea, García-Sastre, Adolfo, Crespo, Mariano Sánchez, Fernández, Nieves

Source: In BBA - Molecular Basis of Disease June 2024 1870(5)

Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection.

Authors: Schwab, Lara S. U.^1,2 (AUTHOR) ccoch@gmx.net, Villalón-Letelier, Fernando¹ (AUTHOR) fernandojavier.villalon@mssm.edu, Tessema, Melkamu B.¹ (AUTHOR) melkamubezie.tessema@unimelb.edu.au, Londrigan, Sarah L.¹ (AUTHOR) sarahll@unimelb.edu.au, Brooks, Andrew G.¹ (AUTHOR) agbrooks@unimelb.edu.au, Hurt, Aeron³ (AUTHOR) aeron.hurt@roche.com, Coch, Christoph² (AUTHOR) zillinger@uni-bonn.de, Zillinger, Thomas² (AUTHOR) gunther.hartmann@uni-bonn.de, Hartmann, Gunther² (AUTHOR), Reading, Patrick C.^1,3 (AUTHOR) preading@unimelb.edu.au

Source: Viruses (1999-4915). Jul2022, Vol. 14 Issue 7, pN.PAG-N.PAG. 18p.

Subject Terms: *LABORATORY mice, *RNA virus infections, *ANIMAL disease models, *INFLUENZA, *INFLUENZA A virus, *INFLUENZA viruses, *VIRUS diseases

Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

Authors: Watterson, Daniel, Wijesundara, Danushka K, Modhiran, Naphak, Mordant, Francesca L, Li, Zheyi, Avumegah, Michael S, McMillan, Christopher LD, Lackenby, Julia, Guilfoyle, Kate, Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey TM, Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L, Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam, Zhou, Qi, Brockman, David A, Morgan, Sherry J, Lau, Cora, Tran, Mai H, Tapley, Peter, Villalón‐Letelier, Fernando, Barnes, James, Young, Andrew, Jaberolansar, Noushin, Scott, Connor AP, Isaacs, Ariel, Amarilla, Alberto A, Khromykh, Alexander A, Brand, Judith MA, Reading, Patrick C, Ranasinghe, Charani, Subbarao, Kanta, Munro, Trent P, Young, Paul R, Chappell, Keith J

Source: Clinical & translational immunology. 10(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121044602.0x000001&indx=1&recIds=ETOCvdc_100121044602.0x000001

Caveats of Using Overexpression Approaches to Screen Cellular Host IFITM Proteins for Antiviral Activity.

Authors: Meischel, Tina, Fritzlar, Svenja, Villalón-Letelier, Fernando, Smith, Jeffrey M., Brooks, Andrew G., Reading, Patrick C., Londrigan, Sarah L.

Source: Pathogens; Apr2023, Vol. 12 Issue 4, p519, 13p

Subject Terms: SYNTHETIC proteins, ANTIVIRAL agents, GENETIC overexpression, PROTEINS, GENE expression, INFLUENZA A virus

Host Cell Restriction Factors that Limit Influenza A Infection.

Authors: Villalón-Letelier, Fernando¹ fvillalon@student.unimelb.edu.au, Brooks, Andrew G.¹ agbrooks@unimelb.edu.au, Saunders, Philippa M.¹ philippa.saunders@unimelb.edu.au, Londrigan, Sarah L.¹ sarahll@unimelb.edu.au, Reading, Patrick C.^1,2 preading@unimelb.edu.au;

Source: Viruses (1999-4915). Dec2017, Vol. 9 Issue 12, p376. 18p.

Subject Terms: *INFLUENZA A virus, H1N1 subtype, *THERAPEUTIC use of interferons, *ECTOPIC hormones, *GENE silencing, *ANTIVIRAL agents, *THERAPEUTICS

Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc.

Authors: Barriga, Gonzalo P.¹, Villalón-Letelier, Fernando¹, Márquez, Chantal L.¹, Bignon, Eduardo A.¹, Acuña, Rodrigo¹, Ross, Breyan H.², Monasterio, Octavio³, Mardones, Gonzalo A.², Vidal, Simon E.¹, Tischler, Nicole D.¹ ntischler@cienciavida.org

Source: PLoS Neglected Tropical Diseases. 7/14/2016, Vol. 10 Issue 7, p1-23. 23p.

Subject Terms: *HANTAVIRUS diseases, *VIRUS diseases, *HANTAVIRUS pulmonary syndrome, *GLYCOPROTEIN genetics, *PROTEIN genetics

Unraveling the role of the MOV10 RNA helicase during influenza A virus infection.

Authors: Villalón-Letelier, Fernando¹, Reading, Patrick C.² preading@unimelb.edu.au

Source: Biochemical Journal. 3/29/2019, Vol. 476 Issue 6, p1005-1008. 4p.

Subject Terms: *RNA helicase, *VIRUS diseases, *INFLUENZA A virus, *CYTOPLASMIC granules, *HELICASES, *H1N1 influenza

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MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells

Authors: Villalón-Letelier, Fernando, Brooks, Andrew G., Londrigan, Sarah L., Reading, Patrick C.

Source: mBio; September 2021, Vol. 12 Issue: 5