Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparibResearch in context

Authors: Xiaonan Zhang, Natallia Rameika, Lei Zhong, Verónica Rendo, Margus Veanes, Snehangshu Kundu, Sandro Nuciforo, Jordan Dupuis, Muhammad Al Azhar, Ioanna Tsiara, Pauline Seeburger, Shahed Al Nassralla, Viktor Ljungström, Richard Svensson, Ivaylo Stoimenov, Per Artursson, Markus H. Heim, Daniel Globisch, Tobias Sjöblom

Source: EBioMedicine, Vol 109, Iss , Pp 105368- (2024)

Subject Terms: Loss of heterozygosity, Loss of function, Hepatocellular carcinomas, CYP2D6 and talazoparib, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424004043; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/c93831231c574e67b595b2f52334f442

Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting

Authors: Tatjana Pandzic, Claes Ladenvall, Marie Engvall, Mattias Mattsson, Monica Hermanson, Lucia Cavelier, Viktor Ljungström, Panagiotis Baliakas

Source: HemaSphere, Vol 6, Iss 8, p e761 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000761; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/03f3bf67f6c54b7fa16ba2662a18f7bf

Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer

Authors: Veronica Rendo, Snehangshu Kundu, Natallia Rameika, Viktor Ljungström, Richard Svensson, Kimmo Palin, Lauri Aaltonen, Ivaylo Stoimenov, Tobias Sjöblom

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0075eeada5c6431e9aaae378bc12e7b8

Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia

Authors: P. Martijn Kolijn, Alice F. Muggen, Viktor Ljungström, Andreas Agathangelidis, Ingrid L. M. Wolvers-Tettero, H. Berna Beverloo, Karol Pál, Paul J. Hengeveld, Nikos Darzentas, Rudi W. Hendriks, Jacques J. M. van Dongen, Richard Rosenquist, Anton W. Langerak

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: CLL (Chronic Lymphocytic Leukemia), Familial CLL, BCR stereotypy, IGLV3-21 R110, CLL development, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.740083/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/348023aaa5874eb98b52a2826f636eb1

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study

Authors: Lesley-Ann Sutton, Viktor Ljungström, Anna Enjuanes, Diego Cortese, Aron Skaftason, Eugen Tausch, Katerina Stano Kozubik, Ferran Nadeu, Marine Armand, Jikta Malcikova, Tatjana Pandzic, Jade Forster, Zadie Davis, David Oscier, Davide Rossi, Paolo Ghia, Jonathan C. Strefford, Sarka Pospisilova, Stephan Stilgenbauer, Frederic Davi, Elias Campo, Kostas Stamatopoulos, Richard Rosenquist, European Research Initiative on CLL (ERIC)

Source: Haematologica, Vol 106, Iss 3 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9711; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/715f66afe1e34e4ea30982ecf017a715

Author Correction: Targeted sequencing reveals the somatic mutation landscape in a Swedish breast cancer cohort

Authors: Argyri Mathioudaki, Viktor Ljungström, Malin Melin, Maja Louise Arendt, Jessika Nordin, Åsa Karlsson, Eva Murén, Pushpa Saksena, Jennifer R. S. Meadows, Voichita D. Marinescu, Tobias Sjöblom, Kerstin Lindblad-Toh

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/05a9286da6e546c984a1841ce12545d4

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

Authors: Andreas Agathangelidis, Viktor Ljungström, Lydia Scarfò, Claudia Fazi, Maria Gounari, Tatjana Pandzic, Lesley-Ann Sutton, Kostas Stamatopoulos, Giovanni Tonon, Richard Rosenquist, Paolo Ghia

Source: Haematologica, Vol 103, Iss 5 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8457; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/9b61864ba571454587beb12f1d0fcdb2

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Authors: Veronika Navrkalova, Emma Young, Panagiotis Baliakas, Lenka Radova, Lesley-Ann Sutton, Karla Plevova, Larry Mansouri, Viktor Ljungström, Stavroula Ntoufa, Zadie Davis, Gunnar Juliusson, Karin E. Smedby, Chrysoula Belessi, Panagiotis Panagiotidis, Tasoula Touloumenidou, Frederic Davi, Anton W. Langerak, Paolo Ghia, Jonathan C. Strefford, David Oscier, Jiri Mayer, Kostas Stamatopoulos, Sarka Pospisilova, Richard Rosenquist, Martin Trbusek

Source: Haematologica, Vol 101, Iss 9 (2016)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7831; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/c3d075fc37da4bfbbe723124a9af0818

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting

Authors: Lesley-Ann Sutton, Viktor Ljungström, Larry Mansouri, Emma Young, Diego Cortese, Veronika Navrkalova, Jitka Malcikova, Alice F. Muggen, Martin Trbusek, Panagiotis Panagiotidis, Frederic Davi, Chrysoula Belessi, Anton W. Langerak, Paolo Ghia, Sarka Pospisilova, Kostas Stamatopoulos, Richard Rosenquist

Source: Haematologica, Vol 100, Iss 3 (2015)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7309; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/32d6b0158569438e91c94271af6b9834

Bioinformatic Challenges in Clinical Diagnostic Application of Targeted Next Generation Sequencing: Experience from Pheochromocytoma.

Authors: Joakim Crona, Viktor Ljungström, Staffan Welin, Martin K Walz, Per Hellman, Peyman Björklund

Source: PLoS ONE, Vol 10, Iss 7, p e0133210 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4521794?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/53496fd67d6b4d7783e8425453e51744