Activation of PIEZO1 Attenuates Kidney Cystogenesis In Vitro and Ex Vivo

Authors: Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C. Harris, Seth L. Alper, Y.S. Prakash, Arthur Beyder, Vicente E. Torres, Fouad T. Chebib

Source: Kidney360, Vol 5, Iss 11, Pp 1601-1612 (2024)

Subject Terms: Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://journals.lww.com/10.34067/KID.0000000598; https://doaj.org/toc/2641-7650

Access URL: https://doaj.org/article/0166253704804f15a97b1b023d1fa2e5

OVERTURE: A Worldwide, Prospective, Observational Study of Disease Characteristics in Patients With ADPKD

Authors: Ronald D. Perrone, Dorothee Oberdhan, John Ouyang, Daniel G. Bichet, Klemens Budde, Arlene B. Chapman, Berenice Y. Gitomer, Shigeo Horie, Albert C.M. Ong, Vicente E. Torres, A. Neil Turner, Holly Krasa

Source: Kidney International Reports, Vol 8, Iss 5, Pp 989-1001 (2023)

Subject Terms: autosomal dominant polycystic kidney disease, cohort, disease progression, natural history, observational, patient-reported outcomes, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024923011701; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/6263893d07674a6789c237002dc53cb4

CD74 Promotes Cyst Growth and Renal Fibrosis in Autosomal Dominant Polycystic Kidney Disease

Authors: Julie Xia Zhou, Alice Shasha Cheng, Li Chen, Linda Xiaoyan Li, Ewud Agborbesong, Vicente E. Torres, Peter C. Harris, Xiaogang Li

Source: Cells, Vol 13, Iss 6, p 489 (2024)

Subject Terms: CD74, cystogenesis, fibrosis, ADPKD, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/6/489; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/07564befe01d476eb3e7cebc11e020e1

Bone health in autosomal dominant polycystic kidney disease (ADPKD) patients after kidney transplantation

Authors: Dalia Zubidat, Christian Hanna, Amarjyot K. Randhawa, Byron H. Smith, Maroun Chedid, Daniel-Hasan N. Kaidbay, Luca Nardelli, Yaman G. Mkhaimer, Reem M. Neal, Charles D. Madsen, Sarah R. Senum, Adriana V. Gregory, Timothy L. Kline, Ziad M. Zoghby, Stephen M. Broski, Naim S. Issa, Peter C. Harris, Vicente E. Torres, Jad G. Sfeir, Fouad T. Chebib

Source: Bone Reports, Vol 18, Iss , Pp 101655- (2023)

Subject Terms: ADPKD, Transplantation, Bone, Mineral metabolism, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352187223000037; https://doaj.org/toc/2352-1872

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The STAGED-PKD 2-Stage Adaptive Study With a Patient Enrichment Strategy and Treatment Effect Modeling for Improved Study Design Efficiency in Patients With ADPKDPlain-Language Summary

Authors: Ronald D. Perrone, Ali Hariri, Pascal Minini, Curie Ahn, Arlene B. Chapman, Shigeo Horie, Bertrand Knebelmann, Michal Mrug, Albert C.M. Ong, York P.C. Pei, Vicente E. Torres, Vijay Modur, Ronald T. Gansevoort

Source: Kidney Medicine, Vol 4, Iss 10, Pp 100538- (2022)

Subject Terms: Autosomal dominant polycystic kidney disease, modeling, study design, total kidney volume, venglustat, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590059522001601; https://doaj.org/toc/2590-0595

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Enhanced MCP-1 Release in Early Autosomal Dominant Polycystic Kidney Disease

Authors: Peter Janssens, Jean-Paul Decuypere, Stéphanie De Rechter, Luc Breysem, Dorien Van Giel, Jaak Billen, An Hindryckx, Luc De Catte, Marcella Baldewijns, Kathleen B.M. Claes, Karl M. Wissing, Koen Devriendt, Bert Bammens, Isabelle Meyts, Vicente E. Torres, Rudi Vennekens, Djalila Mekahli

Source: Kidney International Reports, Vol 6, Iss 6, Pp 1687-1698 (2021)

Subject Terms: ADPKD, chemokine, distal tubule, inflammation, pediatric nephrology, proximal tubule, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S246802492101041X; https://doaj.org/toc/2468-0249

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Per-Treatment Post Hoc Analysis of Clinical Trial Outcomes With Tolvaptan in ADPKD

Authors: Andrew J. Mallett, Ronald D. Perrone, Gopala Rangan, Carmel Hawley, Ragada El-Damanawi, Thomas F. Hiemstra, Carolina Townsend Arellano, Jennifer Lee, Vicente E. Torres

Source: Kidney International Reports, Vol 6, Iss 4, Pp 1032-1040 (2021)

Subject Terms: autosomal dominant polycystic kidney disease, clinical trial, chronic kidney disease, persistence, tolvaptan, treatment effect, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024921000164; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/f06670cb82e94a83981fe34ce5017a8f

Prognostic Value of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease

Authors: Mireille El Ters, Pengcheng Lu, Jonathan D. Mahnken, Jason R. Stubbs, Shiqin Zhang, Darren P. Wallace, Jared J. Grantham, Arlene B. Chapman, Vicente E. Torres, Peter C. Harris, Kyongtae Ty Bae, Douglas P. Landsittel, Frederic F. Rahbari-Oskoui, Michal Mrug, William M. Bennett, Alan S.L. Yu

Source: Kidney International Reports, Vol 6, Iss 4, Pp 953-961 (2021)

Subject Terms: ADPKD, FGF23, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024921000048; https://doaj.org/toc/2468-0249

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Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling

Authors: Xia Zhou, Vicente E. Torres

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: cAMP signaling, protein kinase A (PKA), ADPKD (autosomal dominant polycystic kidney disease), PKD, vassopressin, tolvaptan, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.981963/full; https://doaj.org/toc/2296-889X

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Large Deletions in GANAB and SEC63 Explain 2 Cases of Polycystic Kidney and Liver Disease

Authors: Elena M. Wilson, Jungmin Choi, Vicente E. Torres, Stefan Somlo, Whitney Besse

Source: Kidney International Reports, Vol 5, Iss 5, Pp 727-731 (2020)

Subject Terms: Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024920300309; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/f6e484ad91a448c88269bf2f616df4b2

Kidney Cysts in Hypophosphatemic Rickets With Hypercalciuria: A Case SeriesPlain-Language Summary

Authors: Christian Hanna, Theodora A. Potretzke, Maroun Chedid, Laureano J. Rangel, Jennifer Arroyo, Dalia Zubidat, Peter J. Tebben, Andrea G. Cogal, Vicente E. Torres, Peter C. Harris, David J. Sas, John C. Lieske, Dawn S. Milliner, Fouad T. Chebib

Source: Kidney Medicine, Vol 4, Iss 3, Pp 100419- (2022)

Subject Terms: Case series, HHRH, hypercalciuria, hypophosphatemic rickets with hypercalciuria, kidney cyst, nephrocalcinosis, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590059522000152; https://doaj.org/toc/2590-0595

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Bacterial Cholangitis in Autosomal Dominant Polycystic Kidney and Liver Disease

Authors: William P. Martin, MBChB, MSc, Lisa E. Vaughan, MS, Kotaro Yoshida, MD, PhD, Naoki Takahashi, MD, Marie E. Edwards, BSE, Andrew Metzger, MS, Sarah R. Senum, BS, Tetyana V. Masyuk, PhD, Nicholas F. LaRusso, MD, Matthew D. Griffin, MBChB, DMed, Ziad El-Zoghby, MD, Peter C. Harris, PhD, Walter K. Kremers, PhD, David M. Nagorney, MD, Patrick S. Kamath, MD, Vicente E. Torres, MD, PhD, Marie C. Hogan, MD, PhD

Source: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 3, Iss 2, Pp 149-159 (2019)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2542454819300360; https://doaj.org/toc/2542-4548

Access URL: https://doaj.org/article/4088a39c872b4493bd6a251e5cdc7eb7

Epidemiology of autosomal-dominant polycystic liver disease in Olmsted county

Authors: Tatsuya Suwabe, Alanna M. Chamberlain, Jill M. Killian, Bernard F. King, Adriana V. Gregory, Charles D. Madsen, Xiaofang Wang, Timothy L. Kline, Fouad T. Chebib, Marie C. Hogan, Patrick S. Kamath, Peter C. Harris, Vicente E. Torres

Source: JHEP Reports, Vol 2, Iss 6, Pp 100166- (2020)

Subject Terms: Autosomal-dominant polycystic liver disease, Polycystic liver disease, Hepatic cysts, Liver imaging, Epidemiology, Incidence, Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: http://www.sciencedirect.com/science/article/pii/S2589555920301002; https://doaj.org/toc/2589-5559

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Relationship between caffeine intake and autosomal dominant polycystic kidney disease progression: a retrospective analysis using the CRISP cohort

Authors: Katelyn A. McKenzie, Mirelle El Ters, Vicente E. Torres, Peter C. Harris, Arlene B. Chapman, Michal Mrug, Frederic F. Rahbari-Oskoui, Kyongtae Ty Bae, Douglas P. Landsittel, William M. Bennett, Alan S. L. Yu, Jonathan D. Mahnken

Source: BMC Nephrology, Vol 19, Iss 1, Pp 1-10 (2018)

Subject Terms: Caffeine, CRISP, ESRD, Linear mixed models, Polycystic kidney disease, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12882-018-1182-0; https://doaj.org/toc/1471-2369

Access URL: https://doaj.org/article/9bbfac5e4461453c83ee65a286baa79c

Longitudinal Assessment of Left Ventricular Mass in Autosomal Dominant Polycystic Kidney Disease

Authors: Taimur Dad, Kaleab Z. Abebe, K. Ty Bae, Diane Comer, Vicente E. Torres, Peter G. Czarnecki, Robert W. Schrier, Theodore I. Steinman, Charity G. Moore, Arlene B. Chapman, Diana Kaya, Cheng Tao, William E. Braun, Franz T. Winklhofer, Godela Brosnahan, Marie C. Hogan, Dana C. Miskulin, Frederic Rahbari Oskoui, Michael F. Flessner, Ronald D. Perrone

Source: Kidney International Reports, Vol 3, Iss 3, Pp 619-624 (2018)

Subject Terms: Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024918300019; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/6a879692ab8a41efa2db792d422b2020

Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies

Authors: Fouad T. Chebib, Marie C. Hogan, Ziad M. El-Zoghby, Maria V. Irazabal, Sarah R. Senum, Christina M. Heyer, Charles D. Madsen, Emilie Cornec-Le Gall, Atta Behfar, Peter C. Harris, Vicente E. Torres

Source: Kidney International Reports, Vol 2, Iss 5, Pp 913-923 (2017)

Subject Terms: ADPKD, cardiomyopathies, hypertrophic cardiomyopathy, idiopathic dilated cardiomyopathy, left ventricular noncompaction, polycystic kidney, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024917301353; https://doaj.org/toc/2468-0249

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A Drug Development Tool for Trial Enrichment in Patients With Autosomal Dominant Polycystic Kidney Disease

Authors: Ronald D. Perrone, Mohamad-Samer Mouksassi, Klaus Romero, Frank S. Czerwiec, Arlene B. Chapman, Berenice Y. Gitomer, Vicente E. Torres, Dana C. Miskulin, Steve Broadbent, Jean F. Marier

Source: Kidney International Reports, Vol 2, Iss 3, Pp 451-460 (2017)

Subject Terms: end-stage renal disease, renal function decline, total kidney volume, trial enrichment, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024917300426; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/f08a175e4d28433fa812dcc450b0272e

Total Kidney Volume Is a Prognostic Biomarker of Renal Function Decline and Progression to End-Stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease

Authors: Ronald D. Perrone, Mohamad-Samer Mouksassi, Klaus Romero, Frank S. Czerwiec, Arlene B. Chapman, Berenice Y. Gitomer, Vicente E. Torres, Dana C. Miskulin, Steve Broadbent, Jean F. Marier

Source: Kidney International Reports, Vol 2, Iss 3, Pp 442-450 (2017)

Subject Terms: end-stage renal disease, prognostic biomarker, renal function decline, total kidney volume, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024917300037; https://doaj.org/toc/2468-0249

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Prognostic Enrichment Design in Clinical Trials for Autosomal Dominant Polycystic Kidney Disease: The TEMPO 3:4 Clinical Trial

Authors: Maria V. Irazabal, Jaime D. Blais, Ronald D. Perrone, Ron T. Gansevoort, Arlene B. Chapman, Olivier Devuyst, Eiji Higashihara, Peter C. Harris, Wen Zhou, John Ouyang, Frank S. Czerwiec, Vicente E. Torres

Source: Kidney International Reports, Vol 1, Iss 4, Pp 213-220 (2016)

Subject Terms: autosomal dominant polycystic kidney disease, clinical trials, disease progression, image classification of ADPKD, kidney volume, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024916300511; https://doaj.org/toc/2468-0249

Access URL: https://doaj.org/article/3c5812206ddf438eb09cc9d3003af252

Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease

Authors: Maria V. Irazabal, Vicente E. Torres

Source: Cells, Vol 9, Iss 6, p 1342 (2020)

Subject Terms: chronic kidney disease, reactive oxygen species, oxidative stress, mitochondria, NADPH oxidases, nuclear factor erythroid 2–related factor 2 (Nrf2), Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/6/1342; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/cef87f44254f44e8b82a48ca5aa0b434