Single cell analysis reveals a subset of cytotoxic-like plasmacytoid dendritic cells in people with HIV-1

Authors: Cham, Lamin B. ^{1, 2}, Gunst, Jesper D. ^{1, 2}, Schleimann, Mariane H. ^{1, 2}, Frattari, Giacomo S. ^{1, 2}, Rosas-Umbert, Miriam ^{1, 2}, Vibholm, Line K. ¹, van der Sluis, Renée M. ³, Jakobsen, Martin R. ³, Olesen, Rikke ^{1, 2}, Lin, Lin ³, Tolstrup, Martin ^{1, 2}, Søgaard, Ole S. ^{1, 2, 4, ∗}

Source: In iScience 15 September 2023 26(9)

High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: a randomized, phase 2, crossover trial

Authors: Hansen, Kristoffer S., Mogensen, Trine H., Agergaard, Jane, Schiøttz-Christensen, Berit, Østergaard, Lars, Vibholm, Line K., Leth, Steffen

Source: In The Lancet Regional Health - Europe January 2023 24

SARS-CoV-2 elicits robust adaptive immune responses regardless of disease severity

Authors: Nielsen, Stine SF, Vibholm, Line K, Monrad, Ida, Olesen, Rikke, Frattari, Giacomo S, Pahus, Marie H, Højen, Jesper F, Gunst, Jesper D, Erikstrup, Christian, Holleufer, Andreas, Hartmann, Rune, Østergaard, Lars, Søgaard, Ole S, Schleimann, Mariane H, Tolstrup, Martin

Source: In EBioMedicine June 2021 68

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

Authors: Vibholm, Line K., Nielsen, Stine S.F., Pahus, Marie H., Frattari, Giacomo S., Olesen, Rikke, Andersen, Rebecca, Monrad, Ida, Andersen, Anna H.F., Thomsen, Michelle M., Konrad, Christina V., Andersen, Sidsel D., Højen, Jesper F., Gunst, Jesper D., Østergaard, Lars, Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin

Source: In EBioMedicine February 2021 64

TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes

Authors: Schleimann, Mariane H., Kobberø, Maria-Louise, Vibholm, Line K., Kjær, Kathrine, Giron, Leila B., Busman-Sahay, Kathleen, Chan, Chi Ngai, Nekorchuk, Michael, Schmidt, Manuel, Wittig, Burghardt, Damsgaard, Tine E., Ahlburg, Peter, Hellfritzsch, Michel B., Zuwala, Kaja, Rothemejer, Frederik H., Olesen, Rikke, Schommers, Phillipp, Klein, Florian, Dweep, Harsh, Kossenkov, Andrew, Nyengaard, Jens R., Estes, Jacob D., Abdel-Mohsen, Mohamed, Østergaard, Lars, Tolstrup, Martin, Søgaard, Ole S., Denton, Paul W.

Source: In EBioMedicine July 2019 45:328-340

CD169 (Siglec-1) as a Robust Human Cell Biomarker of Toll-Like Receptor 9 Agonist Immunotherapy.

Authors: Lende, Stine Sofie Frank, Pahus, Marie Høst, Monrad, Ida, Olesen, Rikke, Mahr, Anna R., Vibholm, Line K., Østergaard, Lars, Søgaard, Ole Schmeltz, Andersen, Anna Halling Folkmar, Denton, Paul W., Tolstrup, Martin

Source: Frontiers in Cellular & Infection Microbiology; 7/5/2022, Vol. 12, p1-11, 11p

Subject Terms: BONE marrow, BIOMARKERS, NATURAL immunity, IMMUNOTHERAPY, VIRUS diseases, TOLL-like receptors, MONOCYTES

The Impact of IFNλ4 on the Adaptive Immune Response to SARS-CoV-2 Infection.

Authors: Møhlenberg, Michelle, Monrad, Ida, Vibholm, Line K., Nielsen, Stine S.F., Frattari, Giacomo Schmidt, Schleimann, Mariane Høgsbjerg, Olesen, Rikke, Kjolby, Mads, Gunst, Jesper Damsgaard, Søgaard, Ole Schmeltz, O'Brien, Thomas R., Tolstrup, Martin, Hartmann, Rune

Source: Journal of Interferon & Cytokine Research; Nov2021, Vol. 41 Issue 11, p407-414, 8p

Subject Terms: SARS-CoV-2, COVID-19, ACUTE phase reaction, IMMUNE response, HEPATITIS C virus, LOCUS (Genetics)

Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution.

Authors: Monrad, Ida, Sahlertz, Signe Risgaard, Nielsen, Stine Sofie Frank, Pedersen, Louise Ørnskov, Petersen, Mikkel Steen, Kobel, Carl Mathias, Tarpgaard, Irene Harder, Storgaard, Merete, Mortensen, Klaus Leth, Schleimann, Mariane H, Tolstrup, Martin, Vibholm, Line K

Source: Open Forum Infectious Diseases; Jul2021, Vol. 8 Issue 7, p1-5, 5p

Subject Terms: COVID-19, CONVALESCENT plasma, IMMUNOCOMPROMISED patients, CHRONIC lymphocytic leukemia, SARS-CoV-2

Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals.

Authors: Vibholm, Line K., Konrad, Christina V., Schleimann, Mariane H., Frattari, Giacomo, Winckelmann, Anni, Klastrup, Vibeke, Jensen, Nanna M., Jensen, Sanne S., Schmidt, Manuel, Wittig, Burghardt, Zuwala, Kaja, Mack, Katharina, Olesen, Rikke, Hua, Stephane, Lichterfeld, Mathias, Østergaard, Lars, Denton, Paul W., Tolstrup, Martin, Søgaard, Ole S.

Source: AIDS (02699370); 7/1/2019, Vol. 33 Issue 8, p1315-1325, 11p

Characterization of intact proviruses in blood and lymph node from HIV-infected individuals undergoing analytical treatment interruption.

Authors: Vibholm, Line K.^1,2,3, Lorenzi, Julio C. C.¹, Pai, Joy A.³, Cohen, Yehuda Z.³, Oliveira, Thiago Y.³, Barton, John P.⁴, Noceda, Marco Garcia⁴, Ching-Lan Lu³, Ablanedo-Terrazas, Yuria⁵, Del Rio Estrada, Perla M.⁵, Teran, Gustavo Reyes⁵, Tolstrup, Martin^1,2, Denton, Paul W.^1,2, Damsgaard, Tine¹, Søgaard, Ole S.^1,2, Nussenzweig, Michel C.^3,6 nussen@rockefeller.edu

Source: Journal of Virology. 4/15/2019, Vol. 93 Issue 8, p1-28. 28p.

Subject Terms: *LYMPH nodes, *LYMPHOID tissue, *T cells, *BLOOD, *HIV, *BLOOD cells