Head Kinematics, Blood Biomarkers, and Histology in Large Animal Models of Traumatic Brain Injury and Hemorrhagic Shock

Authors: Mayer, Andrew R., Dodd, Andrew B., Dodd, Rebecca J., Stephenson, David D., Ling, Josef M., Mehos, Carissa J., Patton, Declan A., Robertson-Benta, Cidney R., Gigliotti, Andrew P., Vermillion, Meghan S., Noghero, Alessio

Source: Journal of neurotrauma. 40(19/20):2205-2216

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Effect of TRPV4 Antagonist GSK2798745 on Chlorine Gas-Induced Acute Lung Injury in a Swine Model.

Authors: Vermillion, Meghan S.¹ (AUTHOR) meghan.s.vermillion@gmail.com, Saari, Nathan¹ (AUTHOR) andrewm.nelson@hmh-cdi.org, Bray, Mathieu² (AUTHOR) mathieu.x.bray@gsk.com, Nelson, Andrew M.¹ (AUTHOR) rlbulla@sandia.gov, Bullard, Robert L.¹ (AUTHOR) krudolph@lovelacebiomedical.org, Rudolph, Karin¹ (AUTHOR) agigliotti@lovelacebiomedical.org, Gigliotti, Andrew P.¹ (AUTHOR) jbrendler@lovelacebiomedical.org, Brendler, Jeffrey¹ (AUTHOR) jjantzi@lovelacebiomedical.org, Jantzi, Jacob¹ (AUTHOR) pkuehl@lovelacebiomedical.org, Kuehl, Philip J.¹ (AUTHOR) jake.m@envolbio.com, McDonald, Jacob D.¹ (AUTHOR) wweber@ara.com, Burgert, Mark E.² (AUTHOR) scott.sucoloski@gsk.com, Weber, Waylon¹ (AUTHOR), Sucoloski, Scott² (AUTHOR) david.j.behm@gsk.com, Behm, David J.² (AUTHOR)

Source: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p3949. 19p.

Subject Terms: *LUNGS, *LUNG injuries, *TRPV cation channels, *WATER chlorination, *WATER disinfection, *CHLORINE, *RESPIRATORY organs, *SWINE

Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection

Authors: Pitts, Jared, Babusis, Darius, Vermillion, Meghan S., Subramanian, Raju, Barrett, Kim, Lye, Diane, Ma, Bin, Zhao, Xiaofeng, Riola, Nicholas, Xie, Xuping, Kajon, Adriana, Lu, Xianghan, Bannister, Roy, Shi, Pei-Yong, Toteva, Maria, Porter, Danielle P., Smith, Bill J., Cihlar, Tomas, Mackman, Richard, Bilello, John P.

Source: In Antiviral Research July 2022 203

Survival Rates and Biomarkers in a Large Animal Model of Traumatic Brain Injury Combined With Two Different Levels of Blood Loss

Authors: Mayer, Andrew R., Dodd, Andrew B., Ling, Josef M., Stephenson, David D., Rannou-Latella, Julie G., Vermillion, Meghan S., Mehos, Carissa J., Johnson, Victoria E., Gigliotti, Andrew P., Dodd, Rebecca J., Chaudry, Irshad H., Meier, Timothy B., Smith, Douglas H., Bragin, Denis E., Lai, Chen, Wagner, Chelsea L., Guedes, Vivian A., Gill, Jessica M., Kinsler, Rachel

Source: Shock. 55(4):554-562

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181580774.0x000001&indx=1&recIds=ETOCvdc_100181580774.0x000001

A systematic review of large animal models of combined traumatic brain injury and hemorrhagic shock

Authors: Mayer, Andrew R., Dodd, Andrew B., Vermillion, Meghan S., Stephenson, David D., Chaudry, Irshad H., Bragin, Denis E., Gigliotti, Andrew P., Dodd, Rebecca J., Wasserott, Benjamin C., Shukla, Priyank, Kinsler, Rachel, Alonzo, Sheila M.

Source: In Neuroscience and Biobehavioral Reviews September 2019 104:160-177

Discovery of GS-7682, a Novel 4′-Cyano-Modified C‑Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

Authors: Siegel, Dustin S., Hui, Hon C., Pitts, Jared, Vermillion, Meghan S., Ishida, Kazuya, Rautiola, Davin, Keeney, Michael, Irshad, Hammad, Zhang, Lijun, Chun, Kwon, Chin, Gregory, Goyal, Bindu, Doerffler, Edward, Yang, Hai, Clarke, Michael O., Palmiotti, Chris, Vijjapurapu, Arya, Riola, Nicholas C., Stray, Kirsten, Murakami, Eisuke

Source: Journal of Medicinal Chemistry; 8/8/2024, Vol. 67 Issue 15, p12945-12968, 24p

Considerations for design and implementation of vaccine field trials for novel foot-and-mouth disease vaccines

Authors: Lyons, Nicholas A., Knight-Jones, Theodore J.D., Bartels, Chris, Paton, David J., Ferrari, Giancarlo, Vermillion, Meghan S., Brooks, Abdullah W., Motroni, Roxann, Parker, Elizabeth, Hefferin Berquist, Melissa L., Sumption, Keith J., Klement, Eyal

Source: Vaccine. 37(8):1007-1015

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116313175.0x000001&indx=1&recIds=ETOCvdc_100116313175.0x000001

Comparison of Direct and Indirect Methods of Measuring Arterial Blood Pressure in Healthy Male Rhesus Macaques (Macaca mulatta)

Authors: France, Logan K., Vermillion, Meghan S., Garrett, Caroline M.

Source: Journal of the American Association for Laboratory Animal Science. 57(1):64-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN616369397&indx=1&recIds=ETOCRN616369397

Estriol Reduces Pulmonary Immune Cell Recruitment and Inflammation to Protect Female Mice From Severe Influenza

Authors: Vermillion, Meghan S, Ursin, Rebecca L, Attreed, Sarah E, Klein, Sabra L

Source: Endocrinology. 159(9):3306-3320

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A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads

Authors: Pate, Kelly A. Metcalf, Pohlmeyer, Christopher W., Walker-Sperling, Victoria E., Foote, Jeremy B., Najarro, Kevin M., Cryer, Catherine G., Salgado, Maria, Gama, Lucio, Engle, Elizabeth L., Shirk, Erin N., Queen, Suzanne E., Chioma, Stanley, Vermillion, Meghan S., Bullock, Brandon, Li, Ming, Lyons, Claire E., Adams, Robert J., Zink, M. Christine, Clements, Janice E., Mankowski, Joseph L., Blankson, Joel N.

Source: The Journal of Infectious Diseases, 2015 Nov 01. 212(9), 1387-1396.

Access URL: http://www.jstor.org/stable/43709380

Author Correction: Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females

Authors: Potluri, Tanvi, Fink, Ashley L., Sylvia, Kristyn E., Dhakal, Santosh, Vermillion, Meghan S., vom Steeg, Landon, Deshpande, Sharvari, Narasimhan, Harish, Klein, Sabra L.

Source: Npj vaccines. 4(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132529293.0x000001&indx=1&recIds=ETOCvdc_100132529293.0x000001

Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females

Authors: Potluri, Tanvi, Fink, Ashley L., Sylvia, Kristyn E., Dhakal, Santosh, Vermillion, Meghan S., vom Steeg, Landon, Deshpande, Sharvari, Narasimhan, Harish, Klein, Sabra L.

Source: Npj vaccines. 4(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131017092.0x000001&indx=1&recIds=ETOCvdc_100131017092.0x000001

Pregnancy and infection: using disease pathogenesis to inform vaccine strategy

Authors: Vermillion, Meghan S., Klein, Sabra L.

Source: Npj vaccines. 3(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131018711.0x000001&indx=1&recIds=ETOCvdc_100131018711.0x000001

Production of amphiregulin and recovery from influenza is greater in males than females

Authors: Vermillion, Meghan S., Ursin, Rebecca L., Kuok, Denise I. T., vom Steeg, Landon G., Wohlgemuth, Nicholas, Hall, Olivia J., Fink, Ashley L., Sasse, Eric, Nelson, Andrew, Ndeh, Roland, McGrath-Morrow, Sharon, Mitzner, Wayne, Chan, Michael C. W., Pekosz, Andrew, Klein, Sabra L.

Source: Biology of sex differences. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130478382.0x000001&indx=1&recIds=ETOCvdc_100130478382.0x000001

Animal Models of Enterovirus D68 Infection and Disease.

Authors: Vermillion, Meghan S.¹ mvermillion@lovelacebiomedical.org, Dearing, Justin¹, Yun Zhang², Adney, Danielle R.¹, Scheuermann, Richard H.^2,3,4, Pekosz, Andrew⁵, Tarbet, E. Bart⁶

Source: Journal of Virology. Aug2022, Vol. 96 Issue 15, p1-16. 16p.

Subject Terms: *ENTEROVIRUS diseases, *ANIMAL models in research, *ENTEROVIRUSES, *VACCINE approval, *MYELITIS, *DISEASE progression

Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection.

Authors: Vermillion, Meghan S., Murakami, Eisuke, Ma, Bin, Pitts, Jared, Tomkinson, Adrian, Rautiola, Davin, Babusis, Darius, Irshad, Hammad, Seigel, Dustin, Kim, Cynthia, Zhao, Xiaofeng, Niu, Congrong, Yang, Jesse, Gigliotti, Andrew, Kadrichu, Nani, Bilello, John P., Ellis, Scott, Bannister, Roy, Subramanian, Raju, Smith, Bill

Source: Science Translational Medicine; 2/23/2022, Vol. 14 Issue 633, p1-13, 13p

Subject Terms: COVID-19, REMDESIVIR, SARS-CoV-2, CERCOPITHECUS aethiops, ANTIVIRAL agents, FLUTICASONE, COVID-19 treatment, INTRAVENOUS therapy

Company/Entity: UNITED States. Food & Drug Administration

17α-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a randomized control trial.

Authors: Mayer, Andrew R., Dodd, Andrew B., Rannou-Latella, Julie G., Stephenson, David D., Dodd, Rebecca J., Ling, Josef M., Mehos, Carissa J., Robertson-Benta, Cidney R., Pabbathi Reddy, Sharvani, Kinsler, Rachel E., Vermillion, Meghan S., Gigliotti, Andrew P., Sicard, Veronik, Lloyd, Amy L., Erhardt, Erik B., Gill, Jessica M., Lai, Chen, Guedes, Vivian A., Chaudry, Irshad H.

Source: Critical Care; 12/16/2021, Vol. 25 Issue 1, p1-13, 13p

Reproducibility and Characterization of Head Kinematics During a Large Animal Acceleration Model of Traumatic Brain Injury.

Authors: Mayer, Andrew R., Ling, Josef M., Dodd, Andrew B., Rannou-Latella, Julie G., Stephenson, David D., Dodd, Rebecca J., Mehos, Carissa J., Patton, Declan A., Cullen, D. Kacy, Johnson, Victoria E., Pabbathi Reddy, Sharvani, Robertson-Benta, Cidney R., Gigliotti, Andrew P., Meier, Timothy B., Vermillion, Meghan S., Smith, Douglas H., Kinsler, Rachel

Source: Frontiers in Neurology; 6/9/2021, Vol. 12, p1-13, 13p

Subject Terms: BRAIN injuries, HUMAN kinematics, KINEMATICS, CRANIOMETRY, ANGULAR velocity, ANATOMICAL planes

Geographic Terms: YUCATAN (Mexico : State)

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Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females.

Authors: Hall, Olivia J.¹, Limjunyawong, Nathachit², Vermillion, Meghan S.^1,3, Robinson, Dionne P.¹, Wohlgemuth, Nicholas¹, Pekosz, Andrew^1,2, Mitzner, Wayne², Klein, Sabra L.^1,4, Sklein2@jhu.edu

Source: PLoS Pathogens; 9/15/2016, Vol. 12 Issue 9, p1-22, 22p