Driver mutations in myeloid and lymphoid cells point to multipotent progenitor origin of diverse histiocytic neoplasms

Authors: van Halteren, Astrid G. S. ^{1, 2, 3, ∗}, Kemps, Paul G. ^{2, 3}, Forma-Borst, Jelske ⁴, Xiao, Yanling ⁵, van den Oetelaar, Maud A. J. I. ⁶, Gelineau, Nina U. ^{2, 7}, Verdijk, Robert M. ^{3, 8}, Vos, Lydia E. ⁹, Quint, Koen D. ¹⁰, van den Bos, Cor ², Diamond, Eli L. ¹¹, van Laar, Jan A. M. ^{1, 12}

Source: In Blood Neoplasia May 2025 2(2)

Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue

Authors: Kemps, Paul G., Baelde, Hans J., Vorderman, Ruben H. P., Stelloo, Ellen, Swennenhuis, Joost F., Szuhai, Karoly, Lamers, Meindert H., Kenkhuis, Boyd, Al-Hussaini, Maysa, Briaire-de Bruijn, Inge H., Lam, Suk Wai, Bovée, Judith V. M. G., Cleven, Arjen H. G., Verdijk, Robert M., van Noesel, Carel J. M., van Dijk, Marijke R., Scheijde-Vermeulen, Marijn A., Bruggink, Annette H., van Laar, Jan A. M., de Vries, Andrica C. H., Tissing, Wim J. E., van den Bos, Cor, von Deimling, Andreas, van Wezel, Tom, van Halteren, Astrid G. S., Hogendoorn, Pancras C. W.

Source: In Blood 5 December 2024 144(23):2439-2455

Real-world experience with targeted therapy in patients with histiocytic neoplasms in the Netherlands and in Belgium

Authors: Beckers, Erik, van den Berg, Merlijn, van den Bos, Cor, de Bree, Godelieve, Buddingh, Emmeline, Claeys, Kristl, van Daele, Paul, De Haes, Petra, Demandt, Astrid, van Dorp, Suzanne, Hak, Liesbeth, van Halteren, Astrid, van der Houwen, Tim, Jak, Margot, Kerstens, Jeroen, Kwakernaak, Arjan, van Laar, Jan, Leavis, Helen, Leguit, Roos, van de Loosdrecht, Arjan, Morsink, Linde, Mous, Rogier, van Noesel, Max, Oostvogels, Rimke, Potjewijd, Judith, Plattel, Wouter, Roeloffzen, Wilfried, Rutgers, Abraham, Tonino, Sanne, Tousseyn, Thomas, Verdijk, Rob, Vermaat, Joost, Woei-A-Jin, Sherida, Kemps, Paul G., Woei-A-Jin, F. J. Sherida H., Schöffski, Patrick, Vanden Bempt, Isabelle, Meyer-Wentrup, Friederike A. G., Dors, Natasja, van Eijkelenburg, Natasha K. A., Scheijde-Vermeulen, Marijn A., Jazet, Ingrid M., Limper, Maarten, Verdijk, Robert M., Donker, Marjolein L., de Jonge, Nick A., van Noesel, Carel J. M., Hebeda, Konnie M., Tonino, Sanne H., van Laar, Jan A. M., van Halteren, Astrid G. S.

Source: In Blood Neoplasia September 2024 1(3)

Primary Meningeal Melanocytic Tumors of the Central Nervous System: A Review from the Ultra-Rare Brain Tumors Task Force of the European Network for Rare Cancers (EURACAN).

Authors: Pellerino, Alessia¹ (AUTHOR) alessia.pellerino@unito.it, Verdijk, Robert M.^2,3 (AUTHOR) r.verdijk@erasmusmc.nl, Nichelli, Lucia⁴ (AUTHOR) lucia.nichelli@aphp.fr, Andratschke, Nicolaus H.⁵ (AUTHOR) nicolaus.andratschke@usz.ch, Idbaih, Ahmed⁶ (AUTHOR) ahmed.idbaih@aphp.fr, Goldbrunner, Roland⁷ (AUTHOR) roland.goldbrunner@uk-koeln.de

Source: Cancers. Jul2024, Vol. 16 Issue 14, p2508. 17p.

Subject Terms: *MENINGES, *DOSE-response relationship (Radiation), *CANCER, *RADIOTHERAPY, *RARE diseases, *CANCER patient medical care, *CENTRAL nervous system, *GENES, *GENETIC mutation, *BRAIN tumors

Geographic Terms: EUROPE

8q Gain Has No Additional Predictive Value in SF3B1MUT Uveal Melanoma but Is Predictive for a Worse Prognosis in Patients with BAP1MUT Uveal Melanoma

Authors: Kilic, Emine, de Klein, Annelies, Brosens, Erwin, Naus, Nicole C., Paridaens, Dion, Yavuzyigitoglu, Serdar, Drabarek, Wojtek, Nguyen, Josephine Q.N., Vaarwater, Jolanda, Verdijk, Robert M., Kiliç, Emine

Source: In Ophthalmology Science March-April 2024 4(2)

Uveal melanoma modeling in mice and zebrafish

Authors: van den Bosch, Quincy C.C., de Klein, Annelies, Verdijk, Robert M., Kiliç, Emine, Brosens, Erwin

Source: In BBA - Reviews on Cancer January 2024 1879(1)

A Multicenter Study Validates the WHO 2022 Classification for Conjunctival Melanocytic Intraepithelial Lesions With Clinical and Prognostic Relevance

Authors: Mudhar, Hardeep Singh, Krishna, Yamini, Cross, Simon, Auw-Haedrich, Claudia, Barnhill, Raymond, Cherepanoff, Svetlana, Eagle, Ralph, Farmer, James, Folberg, Robert, Grossniklaus, Hans, Herwig-Carl, Martina C., Hyrcza, Martin, Lassalle, Sandra, Loeffler, Karin U., Moulin, Alexandre, Milman, Tatyana, Verdijk, Robert M., Heegaard, Steffen, Coupland, Sarah E.

Source: In Laboratory Investigation January 2024 104(1)

The 5th Edition of the World Health Organization Classification of Tumours of the Eye and Orbit

Authors: Milman, Tatyana, Grossniklaus, Hans E., Goldman-Levy, Gabrielle, Kivelä, Tero T., Coupland, Sarah E., White, Valerie A., Mudhar, Hardeep Singh, Eberhart, Charles G., Verdijk, Robert M., Heegaard, Steffen, Gill, Anthony J., Jager, Martine J., Rodriguez-Reyes, Aberlardo A., Esmaeli, Bita, Hodge, Jennelle C., Cree, Ian A.

Source: Ocular oncology and pathology. 9(3/4):71-95

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192933285.0x000001&indx=1&recIds=ETOCvdc_100192933285.0x000001

HLA expression as a risk factor for metastases of cutaneous squamous-cell carcinoma in organ- transplant recipients

Authors: de Jong, Estella, Quint, Koen D., El Ghalbzouri, Abdoelwaheb, Verdijk, Robert M., Goeman, Jelle J., Heidt, Sebastiaan, Claas, Frans H.J., de Fijter, Johan W., Genders, Roel E., Vermeer, Maarten H., Bouwes Bavinck, Jan Nico

Source: Human immunology. 84(3):208-213

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188781588.0x000001&indx=1&recIds=ETOCvdc_100188781588.0x000001

Lysosomal glycogen accumulation in Pompe disease results in disturbed cytoplasmic glycogen metabolism

Authors: Canibano‐Fraile, Rodrigo, Harlaar, Laurike, Santos, Carlos A., Hoogeveen‐Westerveld, Marianne, Demmers, Jeroen A. A., Snijders, Tim, Lijnzaad, Philip, Verdijk, Robert M., Beek, Nadine A. M. E., Doorn, Pieter A., Ploeg, Ans T., Brusse, Esther, Pijnappel, W. W. M. Pim, Schaaf, Gerben J.

Source: Journal of inherited metabolic disease. 46(1):101-115

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173160690.0x000001&indx=1&recIds=ETOCvdc_100173160690.0x000001

Increased Histological Tumor Pigmentation in Uveal Melanoma Is Related to Eye Color and Loss of Chromosome 3/BAP1

Authors: Gelmi, Maria Chiara, Wierenga, Annemijn P.A., Kroes, Wilma G.M., van Duinen, Sjoerd G., Karuntu, Jessica S., Marinkovic, Marina, Bleeker, Jaco C., Luyten, Gregorius P.M., Vu, T.H. Khanh, Verdijk, Robert M., Jager, Martine J.

Source: In Ophthalmology Science September 2023 3(3)

Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study

Authors: Kemps, Paul G., Zondag, Timo C. E., Arnardóttir, Helga B., Solleveld-Westerink, Nienke, Borst, Jelske, Steenwijk, Eline C., van Egmond, Demi, Swennenhuis, Joost F., Stelloo, Ellen, Trambusti, Irene, Verdijk, Robert M., van Noesel, Carel J. M., Cleven, Arjen H. G., Scheijde-Vermeulen, Marijn A., Koudijs, Marco J., Krsková, Lenka, Hawkins, Cynthia, Egeler, R. Maarten, Brok, Jesper, von Bahr Greenwood, Tatiana, Svojgr, Karel, Beishuizen, Auke, van Laar, Jan A. M., Pötschger, Ulrike, Hutter, Caroline, Sieni, Elena, Minkov, Milen, Abla, Oussama, van Wezel, Tom, van den Bos, Cor, van Halteren, Astrid G. S.

Source: In Blood Advances 28 February 2023 7(4):664-679

Tissue IgG2/IgG4 Ratio as an Additional Tool to Distinguish IgG4-Related Disease From Other Fibroinflammatory Disorders

Authors: Detiger, Sanne E., Paridaens, Dion, van Hagen, Martin, Karim, Faiz, van Laar, Jan A.M., Verdijk, Robert M.

Source: Applied immunohistochemistry & molecular morphology. 30(7):517-525

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194436509.0x000001&indx=1&recIds=ETOCvdc_100194436509.0x000001

ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition

Authors: Kemps, Paul G., Picarsic, Jennifer, Durham, Benjamin H., Hélias-Rodzewicz, Zofia, Hiemcke-Jiwa, Laura, van den Bos, Cor, van de Wetering, Marianne D., van Noesel, Carel J.M., van Laar, Jan A.M., Verdijk, Robert M., Flucke, Uta E., Hogendoorn, Pancras C.W., Woei-A-Jin, F. J. Sherida H., Sciot, Raf, Beilken, Andreas, Feuerhake, Friedrich, Ebinger, Martin, Möhle, Robert, Fend, Falko, Bornemann, Antje, Wiegering, Verena, Ernestus, Karen, Méry, Tina, Gryniewicz-Kwiatkowska, Olga, Dembowska-Baginska, Bozenna, Evseev, Dmitry A., Potapenko, Vsevolod, Baykov, Vadim V., Gaspari, Stefania, Rossi, Sabrina, Gessi, Marco, Tamburrini, Gianpiero, Héritier, Sébastien, Donadieu, Jean, Bonneau-Lagacherie, Jacinthe, Lamaison, Claire, Farnault, Laure, Fraitag, Sylvie, Jullié, Marie-Laure, Haroche, Julien, Collin, Matthew, Allotey, Jackie, Madni, Majid, Turner, Kerry, Picton, Susan, Barbaro, Pasquale M., Poulin, Alysa, Tam, Ingrid S., El Demellawy, Dina, Empringham, Brianna, Whitlock, James A., Raghunathan, Aditya, Swanson, Amy A., Suchi, Mariko, Brandt, Jon M., Yaseen, Nabeel R., Weinstein, Joanna L., Eldem, Irem, Sisk, Bryan A., Sridhar, Vaishnavi, Atkinson, Mandy, Massoth, Lucas R., Hornick, Jason L., Alexandrescu, Sanda, Yeo, Kee Kiat, Petrova-Drus, Kseniya, Peeke, Stephen Z., Muñoz-Arcos, Laura S., Leino, Daniel G., Grier, David D., Lorsbach, Robert, Roy, Somak, Kumar, Ashish R., Garg, Shipra, Tiwari, Nishant, Schafernak, Kristian T., Henry, Michael M., van Halteren, Astrid G.S., Abla, Oussama, Diamond, Eli L., Emile, Jean-François

Source: Blood. 139(2):256-280

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183242342.0x000001&indx=1&recIds=ETOCvdc_100183242342.0x000001

Novel insights into the pathophysiology of proliferative vitreoretinopathy: The role of vitreoschisis‐induced vitreous cortex remnants

Authors: Overdam, Koen A., Bosch, Thierry P.P., Etten, Peter G., Uppal, Gurmit S., Veckeneer, Marc, Verdijk, Robert M.

Source: Acta ophthalmologica. 100(8):e1749-e1759

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164439420.0x000001&indx=1&recIds=ETOCvdc_100164439420.0x000001

A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus

Authors: Zoutman, Willem H., Nell, Rogier J., Versluis, Mieke, Pico, Ingrid, Khanh Vu, T.H., Verdijk, Robert M., van der Burg, Mirjam, Langerak, Anton W., van der Velden, Pieter A.

Source: Molecular immunology. 145:109-123

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100160327124.0x000001&indx=1&recIds=ETOCvdc_100160327124.0x000001

Vision loss caused by immunoglobulin G4–related disease of the skull base complicated by a mucocele of the sphenoid sinus

Authors: Detiger, Sanne E., Paridaens, Dion, Verdijk, Robert M., Laar, Jan A.M., Dammers, Ruben, Monserez, Dominiek A., Nagtegaal, A. Paul

Source: International forum of allergy & rhinology. 12(9):1216-1220

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158942454.0x000001&indx=1&recIds=ETOCvdc_100158942454.0x000001

Chromosome 3 and 8q Aberrations in Uveal Melanoma Show Greater Impact on Survival in Patients with Light Iris versus Dark Iris Color

Authors: Wierenga, Annemijn P.A., Brouwer, Niels J., Gelmi, Maria Chiara, Verdijk, Robert M., Stern, Marc-Henri, Bas, Zeynep, Malkani, Kabir, van Duinen, Sjoerd G., Ganguly, Arupa, Kroes, Wilma G.M., Marinkovic, Marina, Luyten, Gregorius P.M., Shields, Carol L., Jager, Martine J.

Source: Ophthalmology. 129(4):421-430

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157603962.0x000001&indx=1&recIds=ETOCvdc_100157603962.0x000001

Identification of diagnostic and prognostic genetic alterations in uveal melanoma using RNA sequencing.

Authors: Nell, Rogier J., Versluis, Mieke, Cats, Davy, Mei, Hailiang, Verdijk, Robert M., Kroes, Wilma G. M., Luyten, Gregorius P. M., Jager, Martine J., van der Velden, Pieter A.

Source: Scientific Reports; 3/10/2025, Vol. 15 Issue 1, p1-11, 11p

Subject Terms: MEDICAL sciences, MEDICAL genetics, UVEAL melanoma, ALTERNATIVE RNA splicing, GENE expression profiling

High C-Reactive Protein Levels Are Related to Better Survival in Patients with Uveal Melanoma

Authors: Meijer, Nikki, de Bruyn, Daniël P., de Klein, Annelies, Paridaens, Dion, Verdijk, Robert M., Berendschot, Tos T.J. M., Brosens, Erwin, Jager, Martine J., Kiliç, Emine

Source: In Ophthalmology Science June 2022 2(2)