Harnessing the immune system: vaccines to fight neurodegenerative diseases

Authors: Gonzalez-Artero, Alba ¹, Pujols, Jordi ^{1, ⁎}, Ventura, Salvador ^{1, 2, ⁎}

Source: In Trends in Molecular Medicine March 2025 31(3):209-212

MIA40 circumvents the folding constraints imposed by TRIAP1 function

Authors: Pujols, Jordi ¹, Fornt-Suñé, Marc ¹, Gil-García, Marcos ¹, Bartolomé-Nafría, Andrea ¹, Canals, Francesc ², Cerofolini, Linda ^{3, 4, 5}, Teilum, Kaare ⁶, Banci, Lucia ^{3, 4, 5}, Esperante, Sebastián A. ^{1, ∗}, Ventura, Salvador ^{1, 7, ∗}

Source: In Journal of Biological Chemistry March 2025 301(3)

Aggregating amyloid resources: A comprehensive review of databases on amyloid-like aggregation

Authors: Iglesias, Valentín ^{a, 1}, Chilimoniuk, Jarosław ^{a, 1}, Pintado-Grima, Carlos ^b, Bárcenas, Oriol ^{b, c}, Ventura, Salvador ^{b, d}, Burdukiewicz, Michał ^{a, e, ⁎}

Source: In Computational and Structural Biotechnology Journal December 2024 23:4011-4018

Bioengineered self-assembled nanofibrils for high-affinity SARS-CoV-2 capture and neutralization

Authors: Behbahanipour, Molood, Navarro, Susanna, Bárcenas, Oriol, Garcia-Pardo, Javier, Ventura, Salvador

Source: In Journal of Colloid And Interface Science 15 November 2024 674:753-765

Small molecules to target tau amyloid aggregation

Authors: Manglano-Artuñedo, Zoe, Peña-Díaz, Samuel, Ventura, Salvador

Source: Neural regeneration research. 19(3):509-511

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191706848.0x000001&indx=1&recIds=ETOCvdc_100191706848.0x000001

An α-helical peptide-based plasmonic biosensor for highly specific detection of α-synuclein toxic oligomers

Authors: Giarola, Juliana Fátima, Santos, Jaime, Estevez, M.-Carmen, Ventura, Salvador, Pallarès, Irantzu, Lechuga, Laura M.

Source: In Analytica Chimica Acta 22 May 2024 1304

Cryo-EM structures of functional and pathological amyloid ribonucleoprotein assemblies

Authors: Garcia-Pardo, Javier, Ventura, Salvador

Source: In Trends in Biochemical Sciences February 2024 49(2):119-133

PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties

Authors: Pinheiro, Francisca, Varejão, Nathalia, Sánchez-Morales, Adrià, Bezerra, Filipa, Navarro, Susanna, Velázquez-Campoy, Adrián, Busqué, Félix, Almeida, Maria Rosário, Alibés, Ramon, Reverter, David, Pallarès, Irantzu, Ventura, Salvador

Source: In European Journal of Medicinal Chemistry 5 December 2023 261

The dynamic landscape of peptide activity prediction

Authors: Bárcenas, Oriol, Pintado-Grima, Carlos, Sidorczuk, Katarzyna, Teufel, Felix, Nielsen, Henrik, Ventura, Salvador, Burdukiewicz, Michał

Source: Computational and Structural Biotechnology Journal. 20:6526-6533

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190062500.0x000001&indx=1&recIds=ETOCvdc_100190062500.0x000001

Is a cure for Parkinson's disease hiding inside us?

Authors: Santos, Jaime, Pallarès, Irantzu, Ventura, Salvador

Source: Trends in biochemical sciences. 47(8):641-644

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167398939.0x000001&indx=1&recIds=ETOCvdc_100167398939.0x000001

One ring is sufficient to inhibit α-synuclein aggregation

Authors: Pena-Díaz, Samuel, Ventura, Salvador

Source: Neural regeneration research. 17(3):508-511

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125007886.0x000001&indx=1&recIds=ETOCvdc_100125007886.0x000001

Prediction of the Effect of pH on the Aggregation and Conditional Folding of Intrinsically Disordered Proteins with SolupHred and DispHred

Authors: Iglesias, Valentín, Pintado-Grima, Carlos, Santos, Jaime, Fornt, Marc, Ventura, Salvador

Source: Methods in molecular biology. 2449:197-212

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629323258&indx=1&recIds=ETOCRN629323258

Protocols for Rational Design of Protein Solubility and Aggregation Properties Using Aggrescan3D Standalone

Authors: Kuriata, Aleksander, Badaczewska-Dawid, Aleksandra E., Pujols, Jordi, Ventura, Salvador, Kmiecik, Sebastian

Source: Methods in molecular biology. 2340:17-40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628787497&indx=1&recIds=ETOCRN628787497

A3D 2.0 Update for the Prediction and Optimization of Protein Solubility

Authors: Pujols, Jordi, Iglesias, Valentín, Santos, Jaime, Kuriata, Aleksander, Kmiecik, Sebastian, Ventura, Salvador

Source: Methods in molecular biology. 2406:65-84

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628712108&indx=1&recIds=ETOCRN628712108

Structural commonalities determined by physicochemical principles in the complex polymorphism of the amyloid state of proteins.

Authors: Errico, Silvia, Fani, Giulia, Ventura, Salvador, Schymkowitz, Joost, Rousseau, Frederic, Trovato, Antonio, Vendruscolo, Michele, Bemporad, Francesco, Chiti, Fabrizio

Source: Biochemical Journal; 1/15/2025, Vol. 482 Issue 2, p87-101, 15p

Subject Terms: NUCLEAR magnetic resonance, ALZHEIMER'S disease, PEPTIDES, PARKINSON'S disease, BANKING industry

The role of amphipathic and cationic helical peptides in Parkinson's disease.

Authors: Pintado‐Grima, Carlos, Ventura, Salvador

Source: Protein Science: A Publication of the Protein Society; Jan2025, Vol. 34 Issue 1, p1-14, 14p

The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains

Authors: Peña-Díaz, Samuel, Pujols, Jordi, Vasili, Eftychia, Pinheiro, Francisca, Santos, Jaime, Manglano-Artuñedo, Zoe, Outeiro, Tiago F., Ventura, Salvador

Source: In Journal of Biological Chemistry May 2022 298(5)

Computational methods to predict protein aggregation

Authors: Navarro, Susanna, Ventura, Salvador

Source: In Current Opinion in Structural Biology April 2022 73

Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability

Authors: Mahía, Alejandro, Peña-Díaz, Samuel, Navarro, Susanna, José Galano-Frutos, Juan, Pallarés, Irantzu, Pujols, Jordi, Díaz-de-Villegas, María D., Gálvez, José A., Ventura, Salvador, Sancho, Javier

Source: In Bioorganic Chemistry December 2021 117

AlphaFold and the amyloid landscape

Authors: Pinheiro, Francisca, Santos, Jaime, Ventura, Salvador

Source: In Journal of Molecular Biology 1 October 2021 433(20)