Successful long-term systemic sclerosis treatment by high-frequent low-dose B cell-depleting therapy

Authors: Moazedi-Fuerst, F.C., Lackner, A., Kreuzer, S.M., Eller, K., Odler, B., Kovacs, G., Flick, H., Talakic, E., Hermann, J., Venhoff, N., Venhoff, A., Hafner, F., Brodmann, M., Jud, Philipp, Yazdani-Biuki, B., Husic, R., Salmhofer, W., Stradner, M.H., Graninger, W.B., Thiel, J., Brezinschek, H.P.

Source: In Journal of Autoimmunity July 2024 147

Renal Recovery for Patients with ANCA-Associated Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan

Authors: Peh, C. Au, Chakera, A., Cooper, B., Kurtkoti, J., Langguth, D., Levidiotis, V., Luxton, G., Mount, P., Mudge, D., Noble, E., Phoon, R., Ranganathan, D., Ritchie, A., Ryan, J., Suranyi, M., Rosenkranz, A., Lhotta, K., Kronbichler, A., Demoulin, N., Bovy, C., Hellemans, R., Hougardy, J., Sprangers, B., Wissing, K., Pagnoux, C., Barbour, S., Brachemi, S., Cournoyer, S., Girard, L., Laurin, L., Liang, P., Philibert, D., Walsh, M., Tesar, V., Becvar, R., Horak, P., Rychlik, I., Szpirt, W., Dieperink, H., Gregersen, J., Ivarsen, P., Krarup, E., Lyngsoe, C., Rigothier, C., Augusto, J., Belot, A., Chauveau, D., Cornec, D., Jourde-Chiche, N., Ficheux, M., Karras, A., Klein, A., Maurier, F., Mesbah, R., Moranne, O., Neel, A., Quemeneur, T., Saadoun, D., Terrier, B., Zaoui, P., Schaier, M., Benck, U., Bergner, R., Busch, M., Floege, J., Grundmann, F., Haller, H., Haubitz, M., Hellmich, B., Henes, J., Hohenstein, B., Hugo, C., Iking-Konert, C., Arndt, F., Kubacki, T., Kotter, I., Lamprecht, P., Lindner, T., Halbritter, J., Mehling, H., Schönermarck, U., Venhoff, N., Vielhauer, V., Witzke, O., Szombati, I., Szucs, G., Garibotto, G., Alberici, F., Brunetta, E., Dagna, L., De Vita, S., Emmi, G., Gabrielli, A., Manenti, L., Pieruzzi, F., Roccatello, D., Salvarani, C., Dobashi, H., Atsumi, T., Fujimoto, S., Hagino, N., Ihata, A., Kaname, S., Kaneko, Y., Katagiri, A., Katayama, M., Kirino, Y., Kitagawa, K., Komatsuda, A., Kono, H., Kurasawa, T., Matsumura, R., Mimura, T., Morinobu, A., Murakawa, Y., Naniwa, T., Nanki, T., Ogawa, N., Oshima, H., Sada, K., Sugiyama, E., Takeuchi, T., Taki, H., Tamura, N., Tsukamoto, T., Yamagata, K., Yamamura, M., van Daele, P., Rutgers, A., Teng, Y., Walker, R., Chua, I., Collins, M., Rabindranath, K., de Zoysa, J., Svensson, M., Grevbo, B., Kalstad, S., Little, M., Clarkson, M., Molloy, E., Pamplona, I. Agraz, Anton, J., Lucia, V. Barrio, Ciggaran, S., Cid, M. Cinta, Encarnacion, M. Diaz, Oliveras, X. Fulladosa, Soler, M. Jose, Rusinol, H. Marco, Praga, M., Porras, L. Quintana, Segarra, A., Bruchfeld, A., Segelmark, M., Soveri, I., Thomaidi, E., Westman, K., Neumann, T., Burnier, M., Daikeler, T., Dudler, J., Hauser, T., Seeger, H., Vogt, B., Jayne, D., Burton, J., Al Jayyousi, R., Amin, T., Andrews, J., Baines, L., Brogan, P., Dasgupta, B., Doulton, T., Flossmann, O., Griffin, S., Harper, J., Harper, L., Kidder, D., Klocke, R., Lanyon, P., Luqmani, R., McLaren, J., Makanjuola, D., McCann, L., Nandagudi, A., Selvan, S., O'Riordan, E., Patel, M., Patel, R., Pusey, C., Rajakariar, R., Robson, J., Robson, M., Salama, A., Smyth, L., Sznajd, J., Taylor, J., Merkel, P., Sreih, A., Belilos, E., Bomback, A., Carlin, J., Chen Lin, Y. Chang, Derebail, V., Dragoi, S., Dua, A., Forbess, L., Geetha, D., Gipson, P., Gohh, R., Greenwood, G.T., Hugenberg, S., Jimenez, R., Kaskas, M., Kermani, T., Kivitz, A., Koening, C., Langford, C., Marder, G., Mohamed, A., Monach, P., Neyra, N., Niemer, G., Niles, J., Obi, R., Owens, C., Parks, D., Podoll, A., Rovin, B., Sam, R., Shergy, W., Silva, A., Specks, U., Spiera, R., Springer, J., Striebich, C., Swarup, A., Thakar, S., Tiliakos, A., Tsai, Y., Waguespack, D., Wasko, M. Chester, Cortazar, Frank B., Niles, John L., Jayne, David R.W., Merkel, Peter A., Bruchfeld, Annette, Yue, Huibin, Schall, Thomas J., Bekker, Pirow

Source: In Kidney International Reports April 2023 8(4):860-870

Macrophage colony-stimulating factor receptor/CD115⁺ non-classical monocytes are expanded in systemic lupus erythematosus and associated with lupus nephritis.

Authors: Zeisbrich, M, Rzepka, R, Finzel, S, Venhoff, N, Voll, RE

Source: Scandinavian Journal of Rheumatology; Mar2025, Vol. 54 Issue 2, p125-134, 10p

Subject Terms: CELL receptors, MACROPHAGE colony-stimulating factor, SYSTEMIC lupus erythematosus, LUPUS nephritis, CONNECTIVE tissue diseases

Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis.

Authors: Wortel, CM, van de Wetering, R., Stork, EM, Kissel, T., Reijm, S., van der Woude, D., van Schie, KA, Trouw, LA, Teng, YKO, Rutgers, A., Heeringa, P., Voll, RE, Rizzi, M., Venhoff, N., Toes, REM, Scherer, HU

Source: Nature Communications; 2/12/2025, Vol. 16 Issue 1, p1-13, 13p

Subject Terms: ANTINEUTROPHIL cytoplasmic antibodies, IMMUNOLOGIC memory, MEDICAL sciences, COMPLEMENT activation, ETIOLOGY of diseases, B cells

S2k-Leitlinie (Kurzfassung): Management der Großgefäßvaskulitiden

Authors: Schirmer, J. H., Aries, P. M., Balzer, K., Berlit, P., Bley, T. A., Buttgereit, F., Czihal, M., Dechant, C., Dejaco, C., Garske, U., Henes, J., Holle, J. U., Holl-Ulrich, K., Lamprecht, P., Nölle, B., Moosig, F., Rech, J., Scheuermann, K., Schmalzing, M., Schmidt, W. A., Schneider, M., Schulze-Koops, H., Venhoff, N., Villiger, P. M., Witte, T., Zänker, M., Hellmich, B.

Source: Zeitschrift für Rheumatologie. 79(9):937-942

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186983480.0x000001&indx=1&recIds=ETOCvdc_100186983480.0x000001

Interstitielle Lungenerkrankungen: Vom Bild zur Therapie. (German)

Alternate Title: Interstitial lung diseases: From imaging to treatment. (English)

Authors: Soriano, D., Nattenmüller, J., Schröder, K., Schygulla, E., Jouanjan, L., Venhoff, N., Jandova, I., Stolz, D., Frye, B. C.

Source: Die Radiologie; Aug2024, Vol. 64 Issue 8, p643-652, 10p

IL-1-Blockade mit Anakinra in der Schwangerschaft

Authors: Venhoff, N., Voll, R. E., Glaser, C., Thiel, J.

Source: ZEITSCHRIFT FUR RHEUMATOLOGIE. 77(2):127-134

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN387829129&indx=1&recIds=ETOCRN387829129

Off-label-Biologikatherapie von ANCA-assoziierten und nicht-ANCA-assoziierten Kleingefäßvaskulitiden

Authors: Venhoff, N., Proft, F., Schulze-Koops, H., Holle, J., Voll, R. E., Iking-Konert, C., Jacobi, A. M., Henes, J., Unger, L., Kneitz, O., Dörner, T., Thiel, J.

Source: Zeitschrift für Rheumatologie. 77(1):21-27

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128825352.0x000001&indx=1&recIds=ETOCvdc_100128825352.0x000001

IL-1-Blockade mit Anakinra in der Schwangerschaft

Authors: Venhoff, N., Voll, R. E., Glaser, C., Thiel, J.

Source: Zeitschrift für Rheumatologie. 77(2):127-134

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129451254.0x000001&indx=1&recIds=ETOCvdc_100129451254.0x000001

Two cases with new onset of ANCA-positive eosinophilic granulomatosis with polyangiitis under treatment with dupilumab: coincidence or causality?

Authors: von Deimling, M., Koehler, T. C., Frye, B. C., Maerker-Hermann, E., Venhoff, N.

Source: Annals of the rheumatic diseases. 82(4):580-580

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631618262&indx=1&recIds=ETOCRN631618262

Identifying organic causes of obsessive-compulsive disorder (OCD): The Freiburg-Diagnostic-Protocol for patients with OCD (FDP-OCD)

Authors: Runge, K., Reisert, M., Feige, B., Nickel, K., Urbach, H., Venhoff, N., Tzschach, A., Schiele, M.A., Hannibal, L., Prüss, H., Domschke, K., Tebartz van Elst, L., Endres, D.

Source: In Neuroscience Applied 2023 2 Supplement 2

Uridine in the prevention and treatment of NRTI-related mitochondrial toxicity
Mitochondrial toxicity and HIV infection: understanding the pathogenesis for a therapeutic approach

Authors: Walker, U., Venhoff, N.

Source: ANTIVIRAL THERAPY. 10(SUPP/2):M117-M124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN056645004&indx=1&recIds=ETOCCN056645004

Émulation d’un essai clinique comparant les corticoïdes versus les corticoïdes plus cyclophosphamide au cours de la granulomatose éosinophilique avec polyangéite sans facteur de mauvais pronostic

Authors: Sorin, B., Papo, M., Sinico, R.A., Teixeira, V., Venhoff, N., Urban, M.L., Iudici, M., Mahrhold, J., Locatelli, F., Cassone, G., Schiavon, F., Seeliger, B., Neumann, T., Kroegel, C., Groh, M., Marvisi, C., Samson, M., Barba, T., Jayne, D., Troilo, A., Thiel, J., Hellmich, B., Monti, S., Montecucco, C., Salvarani, C., Kahn, J.E., Bonnotte, B., Durel, C.A., Puéchal, X., Mouthon, L., Guillevin, L., Emmi, G., Vaglio, A., Porcher, R., Terrier, B.

Source: In La revue de médecine interne December 2024 45 Supplement 2:A419-A420

Émulation d’un essai clinique comparant les corticoïdes versus les corticoïdes plus le cyclophosphamide au cours de la granulomatose éosinophilique avec polyangéite sévère

Authors: Sorin, B., Papo, M., Sinico, R.A., Teixeira, V., Venhoff, N., Urban, M.L., Mahrhold, J., Locatelli, F., Cassone, G., Schiavon, F., Seeliger, B., Neumann, T., Kroegel, C., Groh, M., Marvisi, C., Samson, M., Barba, T., Jayne, D., Troilo, A., Thiel, J., Hellmich, B., Monti, S., Montecucco, C., Salvarani, C., Kahn, J.E., Durel, C.A., Mouthon, L., Guillevin, L., Giacomo, E., Vaglio, A., Porcher, R., Terrier, B.

Source: In La revue de médecine interne June 2024 45 Supplement 1:A104-A104

The Role of HLA DQ2 and DQ8 in Dissecting Celiac-Like Disease in Common Variable Immunodeficiency

Authors: Venhoff, N., Emmerich, F., Neagu, M., Salzer, U., Koehn, C., Driever, S., Kreisel, W., Rizzi, M., Effelsberg, N. M., Kollert, F.

Source: JOURNAL OF CLINICAL IMMUNOLOGY. 33(5):909-916

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How I treat …

Authors: Moosig, F., Reinhold-Keller, E., Holl-Ulrich, K., Feller, A. C., Bley, T., Holle, J. U., Zwerina, J., Lamprecht, P., Dalhoff, K., Venhoff, N.

Source: ZEITSCHRIFT FUR RHEUMATOLOGIE. 71(9):775-784

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN321994749&indx=1&recIds=ETOCRN321994749

Role of Pyrimidine Depletion in the Mitochondrial Cardiotoxicity of Nucleoside Analogue Reverse Transcriptase Inhibitors

Authors: Balcarek, K., Venhoff, N., Deveaud, C., Beauvoit, B., Bonnet, J., Kirschner, J., Venhoff, A.C., Lebrecht, D., Walker, U.A.

Source: JAIDS -HAGERSTOWN MD-. 55(5):550-557

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Oral uridine supplementation antagonizes the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues

Authors: Venhoff, N., Lebrecht, D., Deveaud, C., Beauvoit, B., Bonnet, J., Muller, K., Kirschner, J., Venhoff, A.C., Walker, U.A.

Source: AIDS -LONDON- CURRENT SCIENCE THEN RAPID SCIENCE PUBLISHERS THEN LIPPINCOTT RAVEN-. 24(3):345-352

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN265273827&indx=1&recIds=ETOCRN265273827

Mitochondrial Tubulopathy in Tenofovir Disoproxil Fumarate-Treated Rats

Authors: Lebrecht, D., Venhoff, A.C., Kirschner, J., Wiech, T., Venhoff, N., Walker, U.A.

Source: JAIDS -HAGERSTOWN MD-. 51(3):258-263

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Mitochondrial DNA Depletion in Rat Liver Induced by Fosalvudine Tidoxil, a Novel Nucleoside Reverse Transcriptase Inhibitor Prodrug

Authors: Venhoff, A.C., Lebrecht, D., Reuss, F.U., Heckl-Ostreicher, B., Wehr, R., Walker, U.A., Venhoff, N.

Source: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY -JOURNAL-. 53(7):2748-2751

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN253871270&indx=1&recIds=ETOCRN253871270