Polymer vesicles for the delivery of inhibitors of cariogenic biofilm

Authors: Ahirwar, Parmanand ^{a, 1, 2}, Kozlovskaya, Veronika ^{a, 1, 3}, Pukkanasut, Piyasuda ^a, Nikishau, Pavel ^{a, 4}, Nealy, Sarah ^a, Harber, Gregory ^b, Michalek, Suzanne M. ^b, Antony, Linto ^c, Wu, Hui ^{g, 5}, Kharlampieva, Eugenia ^{a, d, ⁎, 6}, Velu, Sadanandan E. ^{a, e, f, ⁎, 7}

Source: In Dental Materials November 2024 40(11):1937-1953

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

Authors: Lopez-Charcas, Osbaldo, Pukkanasut, Piyasuda, Velu, Sadanandan E., Brackenbury, William J., Hales, Tim G., Besson, Pierre, Gomora, Juan Carlos, Roger, Sébastien

Source: In iScience 23 April 2021 24(4)

Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol.

Authors: Lopez‐Charcas, Osbaldo, Benouna, Oumnia, Lemoine, Roxane, Rosendo‐Pineda, Margarita Jacaranda, Anguheven‐Ledezma, Tonantzin Guadalupe, Sandoval‐Vazquez, Lizeth, Gallegos‐Gomez, Martin Leonardo, Robles‐Martinez, Leticia, Herrera‐Carrillo, Zazil, Ramírez‐Aragón, Miguel, Alfaro, Ana, Chadet, Stéphanie, Ferro, Fabio, Besson, Pierre, Jiang, Lin‐Hua, Velu, Sadanandan E., Guerrero‐Hernandez, Agustín, Roger, Sébastien, Gomora, Juan Carlos

Source: British Journal of Pharmacology; Nov2024, Vol. 181 Issue 22, p4546-4570, 25p

Subject Terms: CANCER cell proliferation, GASTROINTESTINAL cancer, COLON cancer, GOSSYPOL, CELL cycle, CALCIUM channels

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53

Authors: Wang, Wei, Cheng, Jian-Wen, Qin, Jiang-Jiang, Hu, Bo, Li, Xin, Nijampatnam, Bhavitavya, Velu, Sadanandan E., Fan, Jia, Yang, Xin-Rong, Zhang, Ruiwen

Source: In Cancer Letters 10 September 2019 459:156-167

Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis.

Authors: Pukkanasut, Piyasuda, Jaskula-Sztul, Renata, Carlos Gomora, Juan, Velu, Sadanandan E.

Source: Frontiers in Pharmacology; 2024, p1-21, 21p

Subject Terms: SODIUM channels, METASTASIS, CANCER cell migration, SMALL molecules, CANCER cell proliferation, CELL migration

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells

Authors: Dutta, Shilpa, Lopez Charcas, Osbaldo, Tanner, Samuel, Gradek, Frédéric, Driffort, Virginie, Roger, Sébastien, Selander, Katri, Velu, Sadanandan E., Brouillette, Wayne

Source: In Bioorganic & Medicinal Chemistry 15 May 2018 26(9):2428-2436

Retracted: Structural studies of antitumor compounds that target the RING domain of MDM2

Authors: Terrell, James Ross, Tang, Sijia, Faniyi, Oluwafoyinsola Omobodunde, Jeong, In Ho, Yin, Jun, Nijampatnam, Bhavitavya, Velu, Sadanandan E., Wang, Wei, Zhang, Ruiwen, Luo, Ming

Source: Protein science. 31(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184434510.0x000001&indx=1&recIds=ETOCvdc_100184434510.0x000001

Structural studies of antitumor compounds that target the RING domain of MDM2

Authors: Terrell, James Ross, Tang, Sijia, Faniyi, Oluwafoyinsola Omobodunde, Jeong, In Ho, Yin, Jun, Nijampatnam, Bhavitavya, Velu, Sadanandan E., Wang, Wei, Zhang, Ruiwen, Luo, Ming

Source: Protein science. 31(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157127939.0x000001&indx=1&recIds=ETOCvdc_100157127939.0x000001

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

Authors: Xue, Bing, Wang, Wei, Qin, Jiang-Jiang, Nijampatnam, Bhavitavya, Murugesan, Srinivasan, Kozlovskaya, Veronika, Zhang, Ruiwen, Velu, Sadanandan E., Kharlampieva, Eugenia

Source: In Acta Biomaterialia August 2017 58:386-398

An expedient synthesis of murrayaquinone A via a novel oxidative free radical reaction

Authors: McDonald, Jeffrey W., Miller, John E., Kim, Minjee, Velu, Sadanandan E.

Source: Tetrahedron letters. 59(6):550-553

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129332763.0x000001&indx=1&recIds=ETOCvdc_100129332763.0x000001

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels

Authors: Smith, M. Ryan, Vayalil, Praveen K., Zhou, Fen, Benavides, Gloria A., Beggs, Reena R., Golzarian, Hafez, Nijampatnam, Bhavitavya, Oliver, Patsy G., Smith, Robin A.J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee

Source: In Redox Biology August 2016 8:136-148

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

Authors: Ehrhardt, Annette, Chung, W. Joon, Pyle, Louise C., Wang, Wei, Nowotarski, Krzysztof, Mulvihill, Cory M., Ramjeesingh, Mohabir, Hong, Jeong, Velu, Sadanandan E., Lewis, Hal A., Atwell, Shane, Aller, Steve, Bear, Christine E., Lukacs, Gergely L., Kirk, Kevin L., Sorscher, Eric J.

Source: In Journal of Biological Chemistry 22 January 2016 291(4):1854-1865

Recent advances in isolation, synthesis, and evaluation of bioactivities of bispyrroloquinone alkaloids of marine origin

Authors: NIJAMPATNAM, Bhavitavya, DUTTA, Shilpa, VELU, Sadanandan E.

Source: In Chinese Journal of Natural Medicines August 2015 13(8):561-577

New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans

Authors: Zhang, Qiong, Nguyen, Thao, McMichael, Megan, Velu, Sadanandan E., Zou, Jing, Zhou, Xuedong, Wu, Hui

Source: In International Journal of Antimicrobial Agents August 2015 46(2):174-182

Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats

Authors: YU, Jun-Xian, Voruganti, Sukesh, LI, Dan-Dan, Qin, Jiang-Jiang, Nag, Subhasree, Xu, Su, Velu, Sadanandan E., Wang, Wei, ZHANG, Ruiwen

Source: In Chinese Journal of Natural Medicines July 2015 13(7):554-560

Total synthesis of calothrixins A and B via oxidative radical reaction of cyclohexenone with aminophenanthridinedione

Authors: Xu, Su, Nguyen, Thao, Pomilio, Irene, Vitale, Maria C., Velu, Sadanandan E.

Source: In Tetrahedron 2 September 2014 70(35):5928-5933

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents

Authors: Nijampatnam, Bhavitavya, Casals, Luke, Zheng, Ruowen, Wu, Hui, Velu, Sadanandan E.

Source: Bioorganic & medicinal chemistry letters. 26(15):3508-3513

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100033622274.0x000001&indx=1&recIds=ETOCvdc_100033622274.0x000001

Total synthesis of zyzzyanones A–D

Authors: Nadkarni, Dwayaja H., Murugesan, Srinivasan, Velu, Sadanandan E.

Source: In Tetrahedron 20 May 2013 69(20):4105-4113

Elevated levels of NO are localized to distal airways in asthma

Authors: Anderson, John T., Zeng, Meiqin, Li, Qian, Stapley, Ryan, Moore, Doyle Ray, II, Chenna, Balachandra, Fineberg, Naomi, Zmijewski, Jaroslaw, Eltoum, Isam-Eldin, Siegal, Gene P., Gaggar, Amit, Barnes, Stephen, Velu, Sadanandan E., Thannickal, Victor J., Abraham, Edward, Patel, Rakesh P., Lancaster, Jack R., Jr., Chaplin, David D., Dransfield, Mark T., Deshane, Jessy S.

Source: In Free Radical Biology and Medicine 1 June 2011 50(11):1679-1688

Hydrogel-Encapsulated Biofilm Inhibitors Abrogate the Cariogenic Activity of Streptococcus mutans.

Authors: Ahirwar, Parmanand, Kozlovskaya, Veronika, Nijampatnam, Bhavitavya, Rojas, Edwin M., Pukkanasut, Piyasuda, Inman, Daniel, Dolmat, Maksim, Law, Anna C., Schormann, Norbert, Deivanayagam, Champion, Harber, Gregory J., Michalek, Suzanne M., Wu, Hui, Kharlampieva, Eugenia, Velu, Sadanandan E.

Source: Journal of Medicinal Chemistry; 6/22/2023, Vol. 66 Issue 12, p7909-7925, 17p