Cytotoxic effect caspase activation dependent of a genetically engineered fusion protein with a CD154 peptide mimetic (OmpC-CD154p) on B-NHL cell lines is mediated by the inhibition of bcl-6 and YY1 through MAPK p38 activation

Authors: Pantoja-Escobar, Gerardo, Morales-Martínez, Mario, Vega, Gabriel G., Castro-Escarpulli, Graciela, Vega, Mario I.

Source: Leukemia & lymphoma. 60(4):1062-1070

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098745378.0x000001&indx=1&recIds=ETOCvdc_100098745378.0x000001

MicroRNA-7 Regulates Migration and Chemoresistance in Non-Hodgkin Lymphoma Cells Through Regulation of KLF4 and YY1.

Authors: Morales-Martinez, Mario, Vega, Gabriel G., Neri, Natividad, Nambo, M. J, Alvarado, Isabel, Cuadra, Ivonne, Duran-Padilla, M. A., Huerta-Yepez, Sara, Vega, Mario I.

Source: Frontiers in Oncology; 10/27/2020, Vol. 11, pN.PAG-N.PAG, 13p

Subject Terms: CELLULAR control mechanisms, DRUG resistance in cancer cells, NON-Hodgkin's lymphoma, CELL migration, TRANSCRIPTION factors

Cytotoxic effect caspase activation dependent of a genetically engineered fusion protein with a CD154 peptide mimetic (OmpC-CD154p) on B-NHL cell lines is mediated by the inhibition of bcl-6 and YY1 through MAPK p38 activation.

Authors: Pantoja-Escobar, Gerardo, Morales-Martínez, Mario, Vega, Gabriel G., Castro-Escarpulli, Graciela, Vega, Mario I.

Source: Leukemia & Lymphoma; Apr2019, Vol. 60 Issue 4, p1062-1070, 9p

Subject Terms: RECOMBINANT proteins, CELL lines, BCL-2 proteins, HUMORAL immunity, ONTOGENY, SALMONELLA typhi, CHIMERIC proteins

Role of the microRNA-7 (miR-7) in the Inhibition of Chemoresistance and Migration of Lymphoma Non-Hodgkin's through Regulation of YY1 and KLF4

Authors: Morales-Martinez, Mario ^*, Vega, Gabriel G ^*, Neri Munoz, Natividad ^*, Nambo, M. J ^*, Alvarado, Isabel ^*, Cuadra, Ivonne ^*, Duran-Padilla, M.A. ^*, Huerta-Yepez, Sara ^*, Vega, Mario I

Source: In Blood 13 November 2019 134 Supplement 1:5220-5220

p38 MAPK and NF-κB Survival Pathways As Targets for Action of Rituximab In Vivo in a Xenographic Model,

Authors: Vega, Gabriel G ^*, Arteaga-Campos, Monica ^*, Martinez-Paniagua, Melisa ^*, Neri Munoz, Natividad ^*, Nambo, M. J ^*, Alvarado, Isabel ^*, Cuadra, Ivonne ^*, Huerta-Yepez, Sara ^*, Vega, Mario

Source: In Blood 8 December 2017 130 Supplement 1:5199-5199

Analysis of Mir-7 (microRNA-7) Expression in Non-Hodgkin Lymphomas and Its Possible Role in the Regulation of the Transcription Factor KLF4 and YY1

Authors: Morales-Martinez, Mario ^*, Vega, Gabriel G ^*, Rocha-Zavaleta, Leticia ^*, Neri Munoz, Natividad ^*, Nambo, M. J ^*, Alvarado, Isabel ^*, Cuadra, Ivonne ^*, Martinez-Maza, Otoniel ^*, Huerta-Yepez, Sara ^*, Vega, Mario

Source: In Blood 8 December 2017 130 Supplement 1:5143-5143

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Fusion Protein Ompc-CD154 Inhibits Proliferation and Induces Apoptosis in B-NHL Cell Lines By a Mechanism That Involves MAPK P38 and TRAF2 Activation

Authors: Pantoja-Escobar, Gerardo ^*, Romo-Dorantes, Laura ^*, Morales-Martinez, Mario ^*, Vega, Gabriel G ^*, Martinez-Maza, Otoniel ^*, Huerta-Yepez, Sara ^*, Vega, Mario I.

Source: In Blood 2 December 2016 128(22):5306-5306

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Cooperation Between the CD20 Receptor and hIFN-Alpha Receptor in Overriding the Blocked CD20 Cell-Signaling in Rituximab-Resistant B-NHL By the Fusion Protein Anti-CD20-hIFN-Alpha

Authors: Vega, Gabriel G ^*, Franco-Cea, Luz A ^*, Huerta-Yepez, Sara ^*, Mayani, Hector, Martinez-Maza, Otoniel ^*, Bonavida, Benjamin, Vega, Mario I.

Source: In Blood 3 December 2015 126(23):1468-1468

KLF4 and YY1 Are Resistant Factors in NHL and Potential Therapeutic Targets: The New Resistant NF-κb/YY1/KLF4/BclxL/Mcl-1 Axis

Authors: Montecillo-Aguado, Mayra R ^*, Vega, Gabriel G ^*, Mayani, Hector, Huerta-Yepez, Sara ^*, Bonavida, Benjamin, Martinez-Maza, Otoniel ^*, Vega, Mario I.

Source: In Blood 3 December 2015 126(23):1466-1466

Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy.

Authors: VEGA, GABRIEL G., FRANCO-CEA, LUZ ARELI, HUERTA-YEPEZ, SARA, MAYANI, HÉCTOR, MORRISON, SHERIE L., BONAVIDA, BENJAMIN, VEGA, MARIO I.

Source: International Journal of Oncology; Nov2015, Vol. 47 Issue 5, p1735-1748, 14p

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Yin Yang 1 (YY1) Regulates The Transcription Of The Gene Krüppel-Like Factor 4 (KLF4) In Pediatric Burkitt Lymphoma: Clinical Implications

Authors: Vega, Mario I, Valencia-Hipolito, Alberto ^*, Hernandez-Atenogenes, Miriam ^*, Vega, Gabriel G ^*, Mayani, Hector ^*, Huerta-Yepez, Sara ^*, Bonavida, Benjamin, Martinez-Maza, Otoniel ^*

Source: In Blood 15 November 2013 122(21):3004-3004

Upregulation of KLF4 Expression in Pediatric B-NHL Lymphomas and Its Association with Low EFS and Poor Survival Following Treatment with Chemotherapy

Authors: Vega, Mario I, Hernandez-Atenogenes, Miriam ^*, Valencia, Alberto ^*, Vega, Gabriel G ^*, Maldonado-Valenzuela, Altagracia ^*, Ramon, Guillermo ^*, Chen, Haiming, Berenson, James R., Martinez-Maza, Otoniel ^*, Mayani, Hector ^*, Huerta-Yepez, Sara ^*, Bonavida, Benjamin

Source: In Blood 18 November 2011 118(21):5184-5184

Cytotoxic Activity of Anti-CD20-hIFN-α on Rituximab-Resistant B-NHL Clones and Synergy with Chemotherapy,

Authors: Vega, Gabriel G ^*, Vega, Mario I, Huerta-Yepez, Sara ^*, Jazirehi, Ali ^*, Mayani, Hector ^*, Martinez-Maza, Otoniel ^*, Morrison, Sherie ^*, Bonavida, Benjamin

Source: In Blood 18 November 2011 118(21):3499-3499

Unresponsiveness to CHOP Is Associated with Activation of the p38 MAPK Pathway in Patients with DLBCL

Authors: Vega, Mario I, Aviles-Salas, Alejandro ^*, Chalapud, J Ramon ^*, Huerta-Yepez, Sara ^*, Hernandez-Pando, Rogelio ^*, Martinez-Paniagua, Melisa ^*, Martinez-Miguel, Bernardo ^*, Hernandez-Atenogenes, Miriam ^*, Vega, Gabriel G ^*, Chen, Haiming, Berenson, James R., Mayani, Hector ^*, Martinez-Maza, Otoniel ^*, Bonavida, Benjamin

Source: In Blood 18 November 2011 118(21):2647-2647

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