Somatic mutations in FAS pathway increase hemophagocytic lymphohistiocytosis risk in patients with T- and/or NK-cell lymphoma

Authors: Liu, Ying, Sardana, Rohan, Nemirovsky, David, Frosina, Denise, Jungbluth, Achim, Johnson, William T., Vardhana, Santosha, Arcila, Maria, Horwitz, Steven M., Derkach, Andriy, Dogan, Ahmet, Xiao, Wenbin

Source: In Blood Advances 25 June 2024 8(12):3064-3075

Risk of Lymph Node Metastasis in T1b Gastric Cancer

Authors: Vos, Elvira L., Nakauchi, Masaya, Gönen, Mithat, Castellanos, Jason A., Biondi, Alberto, Coit, Daniel G., Dikken, Johan L., D'ugo, Domenico, Hartgrink, Henk, Li, Ping, Nishimura, Makoto, Schattner, Mark, Song, Kyo Young, Tang, Laura H., Uyama, Ichiro, Vardhana, Santosha, Verhoeven, Rob H. A., Wijnhoven, Bas P. L., Strong, Vivian E.

Source: Annals of surgery. 277(2):e339-e345

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186826332.0x000001&indx=1&recIds=ETOCvdc_100186826332.0x000001

Retrospective characterization of nodal marginal zone lymphoma

Authors: Stuver, Robert, Drill, Esther, Qualls, David, Okwali, Michelle, Lee Batlevi, Connie, Caron, Philip C., Dogan, Ahmet, Epstein-Peterson, Zachary D., Falchi, Lorenzo, Hamlin, Paul A., Horwitz, Steven M., Imber, Brandon S., Intlekofer, Andrew M., Johnson, William T., Khan, Niloufer, Kumar, Anita, Lahoud, Oscar B., Lue, Jennifer Kimberly, Matasar, Matthew J., Moskowitz, Alison J., Noy, Ariela, Owens, Colette N., Palomba, M. Lia, Schöder, Heiko, Vardhana, Santosha A., Yahalom, Joachim, Zelenetz, Andrew D., Salles, Gilles, Straus, David J.

Source: In Blood Advances 12 September 2023 7(17):4838-4847

TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy

Authors: Johnson, William T., Ganesan, Nivetha, Epstein-Peterson, Zachary D., Moskowitz, Alison J., Stuver, Robert N., Maccaro, Catherine R., Galasso, Natasha, Chang, Tiffany, Khan, Niloufer, Aypar, Umut, Lewis, Natasha E., Zelenetz, Andrew D., Palomba, M. Lia, Matasar, Matthew J., Noy, Ariela, Hamilton, Audrey M., Hamlin, Paul, Caron, Philip C., Straus, David J., Intlekofer, Andrew M., Lee Batlevi, Connie, Kumar, Anita, Owens, Colette N., Sauter, Craig S., Falchi, Lorenzo, Lue, Jennifer K., Vardhana, Santosha A., Salles, Gilles, Dogan, Ahmet, Schultz, Nikolaus D., Arcila, Maria E., Horwitz, Steven M.

Source: In Blood Advances 12 September 2023 7(17):5172-5186

Bispecific antibodies for the treatment of B-cell lymphoma: promises, unknowns, and opportunities

Authors: Falchi, Lorenzo, Vardhana, Santosha A., Salles, Gilles A. ^∗

Source: In Blood 2 February 2023 141(5):467-480

Long and persistent COVID-19 in patients with hematologic malignancies: from bench to bedside

Authors: Laracy, Justin C., Kamboj, Mini, Vardhana, Santosha A.

Source: Current opinion in infectious diseases. 35(4):271-279

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191474203.0x000001&indx=1&recIds=ETOCvdc_100191474203.0x000001

SARS-CoV-2 in immunocompromised individuals

Authors: DeWolf, Susan, Laracy, Justin C., Perales, Miguel-Angel, Kamboj, Mini, van den Brink, Marcel R.M., Vardhana, Santosha

Source: Immunity. 55(10):1779-1798

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186603386.0x000001&indx=1&recIds=ETOCvdc_100186603386.0x000001

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease

Authors: Docampo, Melissa D., da Silva, Marina B., Lazrak, Amina, Nichols, Katherine B., Lieberman, Sophia R., Slingerland, Ann E., Armijo, Gabriel K., Shono, Yusuke, Nguyen, Chi, Monette, Sebastien, Dwomoh, Emmanuel, Lee, Nicole, Geary, Clair D., Perobelli, Suelen M., Smith, Melody, Markey, Kate A., Vardhana, Santosha A., Kousa, Anastasia I., Zamir, Eli, Greenfield, Itamar, Sun, Joseph C., Cross, Justin R., Peled, Jonathan U., Jenq, Robert R., Stein-Thoeringer, Christoph K., van den Brink, Marcel R.M.

Source: Blood. 139(15):2392-2405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183251551.0x000001&indx=1&recIds=ETOCvdc_100183251551.0x000001

Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses

Authors: Lyudovyk, Olga, Kim, Justin Y., Qualls, David, Hwee, Madeline A., Lin, Ya-Hui, Boutemine, Sawsan R., Elhanati, Yuval, Solovyov, Alexander, Douglas, Melanie, Chen, Eunise, Babady, N. Esther, Ramanathan, Lakshmi, Vedantam, Pallavi, Bandlamudi, Chaitanya, Gouma, Sigrid, Wong, Philip, Hensley, Scott E., Greenbaum, Benjamin, Huang, Alexander C., Vardhana, Santosha A.

Source: In Cancer Cell 11 July 2022 40(7):738-753

Magnesium for T cells: strong to the finish!

Authors: Vardhana, Santosha, Dustin, Michael L.

Source: In Trends in Immunology April 2022 43(4):277-279

A phase 2 biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas

Authors: Moskowitz, Alison J. ^*, Ghione, Paola, Jacobsen, Eric, Ruan, Jia, Schatz, Jonathan H., Noor, Sarah, Myskowski, Patricia, Vardhana, Santosha, Ganesan, Nivetha, Hancock, Helen, Davey, Theresa, Perez, Leslie, Ryu, Sunyoung, Santarosa, Alayna, Dowd, Jack, Obadi, Obadi, Pomerantz, Lauren, Yi, Nancy, Sohail, Samia, Galasso, Natasha, Neuman, Rachel, Liotta, Brielle, Blouin, William, Baik, Jeeyeon, Geyer, Mark B., Noy, Ariela, Straus, David, Kumar, Priyadarshini, Dogan, Ahmet, Hollmann, Travis, Drill, Esther, Rademaker, Jurgen, Schoder, Heiko, Inghirami, Giorgio, Weinstock, David M., Horwitz, Steven M.

Source: In Blood 30 December 2021 138(26):2828-2837

Metabolic regulation of the cancer-immunity cycle

Authors: Somarribas Patterson, Luis F., Vardhana, Santosha A.

Source: In Trends in Immunology November 2021 42(11):975-993

Differences in Ancestry and Presence of Gastric Precursor Lesions in Individuals With Young‐ and Average‐Onset Gastric Cancer.

Authors: Magahis, Patrick T., Cornet, Nicole, Tang, Laura, Arora, Kanika, Hingorani, Neha, King, Stephanie, Markowitz, Arnold J., Schattner, Mark, Shimada, Shoji, Maron, Steven B., Vardhana, Santosha, Lumish, Melissa, Cercek, Andrea, Janjigian, Yelena Y., Coit, Daniel, Mendelsohn, Robin B., Berger, Michael F., Strong, Vivian E., Stadler, Zsofia K., Laszkowska, Monika

Source: Cancer Medicine; Dec2024, Vol. 13 Issue 23, p1-13, 13p

Subject Terms: EAST Asians, STOMACH cancer, SOUTH Asians, MEDICAL screening, METAPLASIA

Disappearing Signet Ring Cell Adenocarcinoma in Gastric Cancer Patients.

Authors: Sreeram, Aravind, Stroobant, Emily E., Laszkowska, Monika, Guilford, Parry, Shimada, Shoji, Nishimura, Makoto, Shah, Sohrab, Vardhana, Santosha, Tang, Laura H., Strong, Vivian E.

Source: Annals of Surgical Oncology: An Oncology Journal for Surgeons; Dec2024, Vol. 31 Issue 13, p9030-9038, 9p

Feasibility and Efficacy of Sentinel Lymph Node Mapping in Gastric Cancer.

Authors: Abate, Miseker, Drebin, Harrison, Shimada, Shoji, Fei, Teng, McKinley, Sophia, Poruk, Katherine, Ferguson, Ben, Neuwirth, Madalyn, Tang, Laura H., Vardhana, Santosha, Strong, Vivian E.

Source: Annals of Surgical Oncology: An Oncology Journal for Surgeons; Oct2024, Vol. 31 Issue 10, p6959-6969, 11p

Disease response upon cessation of methotrexate in a patient with Hodgkin lymphoma treated with pembrolizumab.

Authors: Stuver, Robert¹ stuverr@mskcc.org, Vardhana, Santosha A.¹, Bedmutha, Akshay², Kim Chan, Karmela³, Mirtcheva-Trocheva, Rosna², Nosov, Anton², Schöder, Heiko², Moskowitz, Alison¹

Source: Leukemia & Lymphoma. Dec2023, Vol. 64 Issue 14, p2351-2353. 3p.

Subject Terms: *HODGKIN'S disease, *METHOTREXATE, *PEMBROLIZUMAB

Leveraging insights into cancer metabolism—a symposium report

Authors: Cable, Jennifer, Finley, Lydia, Tu, Benjamin P., Patti, Gary J., Oliver, Trudy G., Vardhana, Santosha, Mana, Miyeko, Ericksen, Russell, Khare, Sanika, DeBerardinis, Ralph, Stockwell, Brent R., Edinger, Aimee, Haigis, Marcia, Kaelin, William

Source: Annals of the New York Academy of Sciences. 1462(1):5-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103020101.0x000001&indx=1&recIds=ETOCvdc_100103020101.0x000001

Cancer Metabolism Drives a Stromal Regenerative Response

Authors: Schwörer, Simon, Vardhana, Santosha A., Thompson, Craig B.

Source: In Cell Metabolism 5 March 2019 29(3):576-591

Consideration of a Novel Surgical Approach in the Management of Gastric Adenocarcinoma and Proximal Polyposis Syndrome.

Authors: Judge, Sean J., Gearty, Sofia V., Catchings, Amanda, Ranganathan, Megha, Roehrl, Michael H., Vardhana, Santosha A., Tang, Laura, Stadler, Zsofia K., Strong, Vivian E.

Source: JCO Precision Oncology; 7/8/2024, Vol. 8, p1-6, 6p

Subject Terms: ADENOCARCINOMA, SYNDROMES

Outcomes of Relapsed and Refractory Primary Mediastinal (Thymic) Large B Cell Lymphoma Treated with Second-Line Therapy and Intent to Transplant

Authors: Vardhana, Santosha, Hamlin, Paul A., Yang, Joanna, Zelenetz, Andrew, Sauter, Craig S., Matasar, Matthew J., Ni, Andy, Yahalom, Joachim, Moskowitz, Craig H.

Source: In Biology of Blood and Marrow Transplantation October 2018 24(10):2133-2138