Cyclooxygenase-2 inhibition prevents renal toxicity but not hypertension during sunitinib treatment

Authors: van Dorst, Daan C.H., Mirabito Colafella, Katrina M., van Veghel, Richard, Garrelds, Ingrid M., de Vries, René, Mathijssen, Ron H.J., Danser, A.H. Jan, Versmissen, Jorie

Source: In European Journal of Pharmacology 5 January 2024 962

Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease

Authors: Bovée, Dominique M., Ren, Liwei, Uijl, Estrellita, Clahsen-van Groningen, Marian C., van Veghel, Richard, Garrelds, Ingrid M., Domenig, Oliver, Poglitsch, Marko, Zlatev, Ivan, Kim, Jae B., Huang, Stephen, Melton, Lauren, Lu, Xifeng, Hoorn, Ewout J., Foster, Don, Danser, A.H. Jan

Source: Hypertension. 77(5):1600-1612

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177010351.0x000001&indx=1&recIds=ETOCvdc_100177010351.0x000001

Counteracting Angiotensinogen Small-Interfering RNA-Mediated Antihypertensive Effects With REVERSIR.

Authors: Dien Ye, Cruz-López, Edwyn O., van Veghel, Richard, Garrelds, Ingrid M., Kasper, Anne, Wassarman, Kelly, Ho-Chou Tu, Zlatev, Ivan, Jan Danser, A. H.

Source: Hypertension (0194911X); Jul2024, Vol. 81 Issue 7, p1491-1499, 9p

Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen

Authors: Uijl, Estrellita, Mirabito Colafella, Katrina M., Sun, Yuan, Ren, Liwei, van Veghel, Richard, Garrelds, Ingrid M., de Vries, René, Poglitsch, Marko, Zlatev, Ivan, Kim, Jae B., Hoorn, Ewout J., Foster, Don, Danser, A.H. Jan

Source: Hypertension. 73(6):1249-1257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080777207.0x000001&indx=1&recIds=ETOCvdc_100080777207.0x000001

Combining renin-angiotensin system blockade and sodium-glucose cotransporter-2 inhibition in experimental diabetes results in synergistic beneficial effects.

Authors: Cruz-López, Edwyn O., Ye, Dien, Stolk, Daniel G., Clahsen-van Groningen, Marian C., van Veghel, Richard, Garrelds, Ingrid M., Poglitsch, Marko, Domenig, Oliver, Alipour Symakani, Rahi S., Merkus, Daphne, Verdonk, Koen, Jan Danser, A.H.

Source: Journal of Hypertension; May2024, Vol. 42 Issue 5, p883-892, 10p

Optimum AT1 receptor-neprilysin inhibition has superior cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats

Authors: Roksnoer, Lodi C.W., van Veghel, Richard, de Vries, René, Garrelds, Ingrid M., Bhaggoe, Usha M., Friesema, Edith C.H., Leijten, Frank P.J., Poglitsch, Marko, Domenig, Oliver, Clahsen-van Groningen, Marian C., Hoorn, Ewout J., Jan Danser, A.H. ^*, Batenburg, Wendy W.

Source: In Kidney International July 2015 88(1):109-120

CYCLOOXYGENASE-2 INHIBITION AS A NEW TOOL TO COMBAT ANGIOGENESIS INHIBITOR-INDUCED HYPERTENSION AND RENAL TOXICITY

Authors: Van Dorst, Daan, Colafella, Katrina Mirabito, Van Doorn, Leni, Van Veghel, Richard, Garrelds, Ingrid, Mathijssen, Ron, Danser, Jan, Versmissen, Jorie

Source: Journal of hypertension. 40(1):e120-e120

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156040567.0x000001&indx=1&recIds=ETOCvdc_100156040567.0x000001

BLOOD PRESSURE-INDEPENDENT RENOPROTECTION IN DIABETIC RATS TREATED WITH SMALL INTERFERING RNA TARGETING LIVER ANGIOTENSINOGEN

Authors: Lopez, Edwyn Omar Cruz, Ren, Liwei, Uijl, Estrellita, Clahsen-Van Groningen, Marian C., Van Veghel, Richard, Garrelds, Ingrid M., Domenig, Oliver, Poglitsch, Marko, Zlatev, Ivan, Rooney, Timothy, Kasper, Anne, Nioi, Paul, Foster, Don, Danser, A.H. Jan

Source: Journal of hypertension. 40(1):e193-e193

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156028590.0x000001&indx=1&recIds=ETOCvdc_100156028590.0x000001

Blood pressure‐independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.

Authors: Cruz‐López, Edwyn O., Ren, Liwei, Uijl, Estrellita, Clahsen‐van Groningen, Marian C., van Veghel, Richard, Garrelds, Ingrid M., Domenig, Oliver, Poglitsch, Marko, Zlatev, Ivan, Rooney, Timothy, Kasper, Anne, Nioi, Paul, Foster, Don, Danser, A. H. Jan

Source: British Journal of Pharmacology; Jan2023, Vol. 180 Issue 1, p80-93, 14p, 1 Diagram, 5 Graphs

Subject Terms: ANGIOTENSINOGEN, NON-coding RNA, SMALL interfering RNA, DIABETIC nephropathies, ANGIOTENSIN II

Effects of angiotensin II and its metabolites in the rat coronary vascular bed: Is angiotensin III the preferred ligand of the angiotensin AT 2 receptor?

Authors: van Esch, Joep H.M., Oosterveer, Chantal R., Batenburg, Wendy W., van Veghel, Richard, Danser, A.H. Jan

Source: In European Journal of Pharmacology 2008 588(2):286-293

THE EFFECTS OF ITI-214 (A NEW PHOSPHODIESTERASE 1 INHIBITOR) ON VASCULAR AGEING FEATURES ASSOCIATED TO DNA REPAIR RESPONSE IN MICE

Authors: Golshiri, Keivan, Ataei, Ehsan, De Vries, Rene', Van Veghel, Richard, Snyder, Gretchen L., Zhang, Lei, Li, Peng, Davis, Robert E., Danser, A.H. Jan, Roks, Anton J.M.

Source: Journal of hypertension. 39(1):e67-e67

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185169289.0x000001&indx=1&recIds=ETOCvdc_100185169289.0x000001

CONTROL OF ANTIHYPERTENSIVE EFFECT MEDIATED BY SMALL INTERFERING RNA TARGETING ANGIOTENSINOGEN

Authors: Uijl, Estrellita, Colafella, Katrina M. Mirabito, Ren, Liwei, Hoorn, Ewout J., Zlatev, Ivan, Kim, Jae B., Huang, Stephen, Melton, Lauren, Foster, Don, Danser, A.H. Jan, Van Veghel, Richard, Garrelds, Ingrid M.

Source: Journal of hypertension. 39(1):e15-e15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185164713.0x000001&indx=1&recIds=ETOCvdc_100185164713.0x000001

Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.

Authors: Uijl, Estrellita, Dien Ye, Liwei Ren, Colafella, Katrina M. Mirabito, van Veghel, Richard, Garrelds, Ingrid M., Lu, Hong S., Daugherty, Alan, Hoorn, Ewout J., Nioi, Paul, Foster, Don, Danser, A. H. Jan, Ye, Dien, Ren, Liwei, Mirabito Colafella, Katrina M

Source: Journal of the American Heart Association; 8/2/2022, Vol. 11 Issue 15, p1-14, 14p

Prostacyclin therapy increases right ventricular capillarisation in a model for flow-associated pulmonary hypertension

Authors: van Albada, Mirjam E., Berger, Rolf M.F., Niggebrugge, Marnix, van Veghel, Richard, Cromme-Dijkhuis, Adri H., Schoemaker, Regien G.

Source: In European Journal of Pharmacology 2006 549(1):107-116

AT2 receptor-mediated vasodilation in the heart: effect of myocardial infarction.

Authors: Schuijt, Martin P., Basdew, Munesh, van Veghel, Richard

Source: American Journal of Physiology; December 2001 pt2, Vol. 281 Issue 6, pH2590-H2596, 7p

Chronic vasopressin V1A but not V2 receptor antagonism prevents heart failure in chronically infarcted rats

Authors: Van Kerckhoven, Roeland ^*, Lankhuizen, Inge, van Veghel, Richard, Saxena, Pramod R, Schoemaker, Regien G

Source: In European Journal of Pharmacology 2 August 2002 449(1-2):135-141

Vascular Ageing Features Caused by Selective DNA Damage in Smooth Muscle Cell.

Authors: Ataei Ataabadi, Ehsan, Golshiri, Keivan, van der Linden, Janette, de Boer, Martine, Duncker, Dirk J., Jüttner, Annika, de Vries, René, Van Veghel, Richard, van der Pluijm, Ingrid, Dutheil, Sophie, Chalgeri, Suman, Zhang, Lei, Lin, Amy, Davis, Robert E., Snyder, Gretchen L., Danser, A. H. Jan, Roks, Anton J. M.

Source: Oxidative Medicine & Cellular Longevity; 8/31/2021, p1-13, 13p

Vascular and renal effects of vasopressin and its antagonists in conscious rats with chronic myocardial infarction; evidence for receptor shift

Authors: Lankhuizen, Inge M, van Veghel, Richard, Saxena, Pramod R, Schoemaker, Regien G ^*

Source: In European Journal of Pharmacology 2001 423(2):195-202

Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein

Authors: Rump, Erik T ^∗, de Vrueh, Remco L.A ^∗, Manoharan, Muthiah ^†, Waarlo, Ingrid H.E ^∗, van Veghel, Richard ^∗, Biessen, Erik A.L ^∗, van Berkel, Theo J.C ^∗, Bijsterbosch, Martin K ^{∗, *}

Source: In Biochemical Pharmacology 2000 59(11):1407-1416

No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension.

Authors: Uijl, Estrellita, Ren, Liwei, Colafella, Katrina M. Mirabito, van Veghel, Richard, Garrelds, Ingrid M., Domenig, Oliver, Poglitsch, Marko, Zlatev, Ivan, Kim, Jae B., Huang, Stephen, Melton, Lauren, Hoorn, Ewout J., Foster, Don, Danser, A. H. Jan

Source: Clinical Science; Jan2021, Vol. 135 Issue 2, p259-274, 16p

Subject Terms: RENIN-angiotensin system, ANGIOTENSIN II, HYPERTENSION, ANGIOTENSINOGEN, ANGIOTENSINS