Signaling pathways and targeted therapies in Ewing sarcoma

Authors: Jia, Ke ^{a, 1}, Cao, Li ^{a, b, 1}, Yu, Yihan ^{a, 1}, Jing, Doudou ^{c, ⁎}, Wu, Wei ^{a, ⁎}, Van Tine, Brian Andrew ^{b, ⁎}, Shao, Zengwu ^{a, ⁎}

Source: In Pharmacology and Therapeutics February 2025 266

Safety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): an open-label, randomised clinical trial

Authors: Mowery, Yvonne M, Ballman, Karla V, Hong, Angela M, Schuetze, Scott M, Wagner, Andrew J, Monga, Varun, Heise, Rachel S, Attia, Steven, Choy, Edwin, Burgess, Melissa A, Bae, Susie, Pryor, David I, Van Tine, Brian A, Tinoco, Gabriel, Chmielowski, Bartosz, Freeman, Carolyn, Gronchi, Alessandro, Meyer, Christian F, Dickson, Mark A, Hartner, Lee, Davis, Lara E, Powers, Benjamin C, Moding, Everett J, Weinhold, Kent J, van de Rijn, Matt, Brigman, Brian E, Riedel, Richard F, Kirsch, David G ^*

Source: In The Lancet 23-29 November 2024 404(10467):2053-2064

Afamitresgene autoleucel for advanced synovial sarcoma and myxoid round cell liposarcoma (SPEARHEAD-1): an international, open-label, phase 2 trial

Authors: D'Angelo, Sandra P ^*, Araujo, Dejka M, Abdul Razak, Albiruni R, Agulnik, Mark, Attia, Steven, Blay, Jean-Yves, Carrasco Garcia, Irene, Charlson, John A, Choy, Edwin, Demetri, George D, Druta, Mihaela, Forcade, Edouard, Ganjoo, Kristen N, Glod, John, Keedy, Vicki L, Le Cesne, Axel, Liebner, David A, Moreno, Victor, Pollack, Seth M, Schuetze, Scott M, Schwartz, Gary K, Strauss, Sandra J, Tap, William D, Thistlethwaite, Fiona, Valverde Morales, Claudia Maria, Wagner, Michael J, Wilky, Breelyn A, McAlpine, Cheryl, Hudson, Laura, Navenot, Jean-Marc, Wang, Tianjiao, Bai, Jane, Rafail, Stavros, Wang, Ruoxi, Sun, Amy, Fernandes, Lilliam, Van Winkle, Erin, Elefant, Erica, Lunt, Colin, Norry, Elliot, Williams, Dennis, Biswas, Swethajit, Van Tine, Brian A

Source: In The Lancet 13-19 April 2024 403(10435):1460-1471

Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness

Authors: Francis, Alicia, Paulovich, Amanda G., Antczak, Andrzej, Green, Anthony, Colaprico, Antonio, Hakimi, Ari, Pruetz, Barb, Hindenach, Barbara, Yadav, Birendra Kumar, Reva, Boris, Fevrier-Sullivan, Brenda, Druker, Brian J., Szczylik, Cezary, Goldthwaite, Charles A., Jr., Birger, Chet, Jones, Corbin D., Rohrer, Daniel C., Tansil, Darlene, Chesla, David, Heiman, David, Duffy, Elizabeth, Schadt, Eri E., Petralia, Francesca, Bromiński, Gabriel, Quiroga-Garza, Gabriela M., Wilson, George D., Li, Ginny Xiaohe, Zhao, Grace, Hsiao, Yi, Hsieh, James, Lubiński, Jan, Bavarva, Jasmin, Huang, Jasmine, Hafron, Jason, Eschbacher, Jennifer, Hon, Jennifer, Francis, Jesse, Freymann, John, Vo, Josh, Wang, Joshua, Kirby, Justin, Zaalishvili, Kakhaber, Ketchum, Karen A., Hoadley, Katherine A., Um, Ki Sung, Qi, Liqun, Domagalski, Marcin J., Tobin, Matt, Dyer, Maureen, Anurag, Meenakshi, Borucki, Melissa, Gillette, Michael A., Birrer, Michael J., Ittmann, Michael M., Roehrl, Michael H., Schnaubelt, Michael, Smith, Michael, Fam, Mina, Roche, Nancy, Vatanian, Negin, Maunganidze, Nicollette, Potapova, Olga, Paklina, Oxana V., VanderKolk, Pamela, Castro, Patricia, Kurzawa, Paweł, Hariharan, Pushpa, Li, Qin, Li, Qing Kay, Dhir, Rajiv, Thangudu, Ratna R., Montgomery, Rebecca, Smith, Richard D., Mareedu, Sailaja, Payne, Samuel H., Cerda, Sandra, Cottingham, Sandra, Haynes, Sarah, Satpathy, Shankha, Richey, Shannon, Singh, Shilpi, Tsang, Shirley X., Cai, Shuang, Cao, Song, Gabriel, Stacey, Carr, Steven A., Liu, Tao, Bauer, Thomas, Le, Toan, Chen, Xi S., Zhang, Xu, Shutack, Yvonne, Zhang, Zhen, Li, Yize, Lih, Tung-Shing M., Dhanasekaran, Saravana M., Mannan, Rahul, Chen, Lijun, Cieslik, Marcin, Wu, Yige, Lu, Rita Jiu-Hsien, Clark, David J., Kołodziejczak, Iga, Hong, Runyu, Chen, Siqi, Zhao, Yanyan, Chugh, Seema, Caravan, Wagma, Naser Al Deen, Nataly, Hosseini, Noshad, Newton, Chelsea J., Krug, Karsten, Xu, Yuanwei, Cho, Kyung-Cho, Hu, Yingwei, Zhang, Yuping, Kumar-Sinha, Chandan, Ma, Weiping, Calinawan, Anna, Wyczalkowski, Matthew A., Wendl, Michael C., Wang, Yuefan, Guo, Shenghao, Zhang, Cissy, Le, Anne, Dagar, Aniket, Hopkins, Alex, Cho, Hanbyul, Leprevost, Felipe da Veiga, Jing, Xiaojun, Teo, Guo Ci, Liu, Wenke, Reimers, Melissa A., Pachynski, Russell, Lazar, Alexander J., Chinnaiyan, Arul M., Van Tine, Brian A., Zhang, Bing, Rodland, Karin D., Getz, Gad, Mani, D.R., Wang, Pei, Chen, Feng, Hostetter, Galen, Thiagarajan, Mathangi, Linehan, W. Marston, Fenyö, David, Jewell, Scott D., Omenn, Gilbert S., Mehra, Rohit, Wiznerowicz, Maciej, Robles, Ana I., Mesri, Mehdi, Hiltke, Tara, An, Eunkyung, Rodriguez, Henry, Chan, Daniel W., Ricketts, Christopher J., Nesvizhskii, Alexey I., Zhang, Hui, Ding, Li

Source: In Cancer Cell 9 January 2023 41(1):139-163

A randomised phase II trial of a trivalent ganglioside vaccine targeting GM2, GD2 and GD3 combined with immunological adjuvant OPT-821 versus OPT-821 alone in metastatic sarcoma patients rendered disease-free by surgery

Authors: Rosenbaum, Evan, Chugh, Rashmi, Ryan, Christopher W., Agulnik, Mark, Milhem, Mohammed M., George, Suzanne, Jones, Robin L., Chmielowski, Bartosz, Van Tine, Brian A., Tawbi, Hussein, Elias, Anthony D., Read, William L., Budd, G. Thomas, Qin, Li-Xuan, Rodler, Eve T., Hirman, Joe, Weiden, Paul, Bennett, Cathryn M., Livingston, Philip O., Ragupathi, Govind, Hansen, David, D'Angelo, Sandra P., Tap, William D., Schwartz, Gary K., Maki, Robert G., Carvajal, Richard D.

Source: In European Journal of Cancer November 2022 176:155-163

Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial

Authors: Gounder, Mrinal M., Razak, Albiruni Abdul, Somaiah, Neeta, Chawla, Sant, Martin-Broto, Javier, Grignani, Giovanni, Schuetze, Scott M., Vincenzi, Bruno, Wagner, Andrew J., Chmielowski, Bartosz, Jones, Robin L., Riedel, Richard F., Stacchiotti, Silvia, Loggers, Elizabeth T., Ganjoo, Kristen N., Le Cesne, Axel, Italiano, Antoine, Garcia del Muro, Xavier, Burgess, Melissa, Piperno-Neumann, Sophie, Ryan, Christopher, Mulcahy, Mary F., Forscher, Charles, Penel, Nicolas, Okuno, Scott, Elias, Anthony, Hartner, Lee, Philip, Tony, Alcindor, Thierry, Kasper, Bernd, Reichardt, Peter, Lapeire, Lore, Blay, Jean-Yves, Chevreau, Christine, Valverde Morales, Claudia Maria, Schwartz, Gary K., Chen, James L., Deshpande, Hari, Davis, Elizabeth J., Nicholas, Garth, Gröschel, Stefan, Hatcher, Helen, Duffaud, Florence, Herráez, Antonio Casado, Beveridge, Roberto Diaz, Badalamenti, Giuseppe, Eriksson, Mikael, Meyer, Christian, von Mehren, Margaret, Van Tine, Brian A., Götze, Katharina, Mazzeo, Filomena, Yakobson, Alexander, Zick, Aviad, Lee, Alexander, Gonzalez, Anna Estival, Napolitano, Andrea, Dickson, Mark A., Michel, Dayana, Meng, Changting, Li, Lingling, Liu, Jianjun, Ben-Shahar, Osnat, Van Domelen, Dane R., Walker, Christopher J., Chang, Hua, Landesman, Yosef, Shah, Jatin J., Shacham, Sharon, Kauffman, Michael G., Attia, Steven

Source: Journal of clinical oncology. 40(22):2479-2490

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171054796.0x000001&indx=1&recIds=ETOCvdc_100171054796.0x000001

Pregnancy outcomes related to the treatment of sarcomas with anthracyclines and/or ifosfamide during pregnancy

Authors: Miller, Devon, Livingston, John A., Park, Yeonhee, Posey, Kristi, Godbole, Sonia, Skubitz, Keith, Robinson, Steven I., Agulnik, Mark, Davis, Lara E., Van Tine, Brian A., Hirbe, Angela C., Parkes, Amanda

Source: Cancer medicine. 11(18):3471-3478

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161216089.0x000001&indx=1&recIds=ETOCvdc_100161216089.0x000001

PHGDH inhibition and FOXO3 modulation drives PUMA-dependent apoptosis in osteosarcoma.

Authors: Oyama, Toshinao, Brashears, Caitlyn B., Rathore, Richa, Benect-Hamilton, Heather, Caldwell, Katharine E., Dirckx, Naomi, Hawkins, William G., Van Tine, Brian A.

Source: Cell Death & Disease; 2/12/2025, Vol. 16 Issue 1, p1-14, 14p

Nirogacestat in patients with desmoid tumors and mutations of adenomatous polyposis coli (APC): Findings from the DeFi trial.

Authors: Federman, Noah, Kasper, Bernd, Reichardt, Peter, Riedel, Richard F., Oton, Ana Belen, Chu, Yucheng, Van Tine, Brian Andrew

Source: Journal of Clinical Oncology; 2025 Supplement 4, Vol. 43, p134-134, 307p

A phase 4, multicenter, global clinical study to evaluate discontinuation and rechallenge of pexidartinib in patients with tenosynovial giant cell tumor previously treated with pexidartinib.

Authors: Desai, Jayesh, Wagner, Andrew J., Carrasco Garcia, Irene, Cesari, Marilena, Gordon, Michael, Lin, Chia‐Chi, Papai, Zsuzsanna, Ryan, Christopher W., Tap, William D., Trent, Jonathan C., Gelderblom, Hans, Grimison, Peter, López Pousa, Antonio, Van Tine, Brian A., Rubinacci, Maria, Dai, Dong, Rajper, Abdul Waheed, Tecson, Kristen, Wooddell, Margaret, Stacchiotti, Silvia

Source: Cancer (0008543X); Jan2025, Vol. 131 Issue 1, p1-14, 14p

Subject Terms: GIANT cell tumors, VISUAL analog scale, PHYSICAL mobility, SURVIVAL rate, CANCER invasiveness

Commentary: A Special Edition in bone sarcoma

Authors: Ludwig, Joseph A, Van Tine, Brian

Source: In Journal of Bone Oncology June 2022 34

Discovery of targeted expression data for novel antibody-based and chimeric antigen receptor-based therapeutics in soft tissue sarcomas using RNA-sequencing: clinical implications

Authors: Pestana, Roberto Carmagnani, Roszik, Jason, Groisberg, Roman, Sen, Shiraj, Van Tine, Brian A., Conley, Anthony P, Subbiah, Vivek

Source: In Current Problems in Cancer October 2021 45(5)

An open-label single-arm phase II study of regorafenib for the treatment of angiosarcoma

Authors: Agulnik, Mark, Schulte, Brian, Robinson, Steven, Hirbe, Angela C., Kozak, Kevin, Chawla, Sant P., Attia, Steven, Rademaker, Alfred, Zhang, Hui, Abbinanti, Susan, Cehic, Rasima, Monga, Varun, Milhem, Mohammed, Okuno, Scott, Van Tine, Brian A.

Source: In European Journal of Cancer September 2021 154:201-208

Concurrent paclitaxel and radiation therapy for the treatment of cutaneous angiosarcoma

Authors: Roy, Amit, Gabani, Prashant, Davis, Elizabeth J., Oppelt, Peter, Merfeld, Emily, Keedy, Vicky L., Zoberi, Imran, Chrisinger, John S.A., Michalski, Jeff M., Van Tine, Brian, Spraker, Matthew B.

Source: In Clinical and Translational Radiation Oncology March 2021 27:114-120

Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma

Authors: Rathore, Richa, Caldwell, Katharine E., Schutt, Charles, Brashears, Caitlyn B., Prudner, Bethany C., Ehrhardt, William R., Leung, Cheuk Hong, Lin, Heather, Daw, Najat C., Beird, Hannah C., Giles, Abigail, Wang, Wei-Lien, Lazar, Alexander J., Chrisinger, John S.A., Livingston, J. Andrew, Van Tine, Brian A.

Source: In Cell Reports 26 January 2021 34(4)

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Authors: Caesar-Johnson, Samantha J., Demchok, John A., Felau, Ina, Kasapi, Melpomeni, Ferguson, Martin L., Hutter, Carolyn M., Sofia, Heidi J., Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Zenklusen, Jean C., Zhang, Jiashan (Julia), Chudamani, Sudha, Liu, Jia, Lolla, Laxmi, Naresh, Rashi, Pihl, Todd, Sun, Qiang, Wan, Yunhu, Wu, Ye, Cho, Juok, DeFreitas, Timothy, Frazer, Scott, Gehlenborg, Nils, Getz, Gad, Heiman, David I., Kim, Jaegil, Lawrence, Michael S., Lin, Pei, Meier, Sam, Noble, Michael S., Saksena, Gordon, Voet, Doug, Zhang, Hailei, Bernard, Brady, Chambwe, Nyasha, Dhankani, Varsha, Knijnenburg, Theo, Kramer, Roger, Leinonen, Kalle, Liu, Yuexin, Miller, Michael, Reynolds, Sheila, Shmulevich, Ilya, Thorsson, Vesteinn, Zhang, Wei, Akbani, Rehan, Broom, Bradley M., Hegde, Apurva M., Ju, Zhenlin, Kanchi, Rupa S., Korkut, Anil, Li, Jun, Liang, Han, Ling, Shiyun, Liu, Wenbin, Lu, Yiling, Mills, Gordon B., Ng, Kwok-Shing, Rao, Arvind, Ryan, Michael, Wang, Jing, Weinstein, John N., Zhang, Jiexin, Abeshouse, Adam, Armenia, Joshua, Chakravarty, Debyani, Chatila, Walid K., de Bruijn, Ino, Gao, Jianjiong, Gross, Benjamin E., Heins, Zachary J., Kundra, Ritika, La, Konnor, Ladanyi, Marc, Luna, Augustin, Nissan, Moriah G., Ochoa, Angelica, Phillips, Sarah M., Reznik, Ed, Sanchez-Vega, Francisco, Sander, Chris, Schultz, Nikolaus, Sheridan, Robert, Sumer, S. Onur, Sun, Yichao, Taylor, Barry S., Wang, Jioajiao, Zhang, Hongxin, Anur, Pavana, Peto, Myron, Spellman, Paul, Benz, Christopher, Stuart, Joshua M., Wong, Christopher K., Yau, Christina, Hayes, D. Neil, Parker, Joel S., Wilkerson, Matthew D., Ally, Adrian, Balasundaram, Miruna, Bowlby, Reanne, Brooks, Denise, Carlsen, Rebecca, Chuah, Eric, Dhalla, Noreen, Holt, Robert, Jones, Steven J.M., Kasaian, Katayoon, Lee, Darlene, Ma, Yussanne, Marra, Marco A., Mayo, Michael, Moore, Richard A., Mungall, Andrew J., Mungall, Karen, Robertson, A. Gordon, Sadeghi, Sara, Schein, Jacqueline E., Sipahimalani, Payal, Tam, Angela, Thiessen, Nina, Tse, Kane, Wong, Tina, Berger, Ashton C., Beroukhim, Rameen, Cherniack, Andrew D., Cibulskis, Carrie, Gabriel, Stacey B., Gao, Galen F., Ha, Gavin, Meyerson, Matthew, Schumacher, Steven E., Shih, Juliann, Kucherlapati, Melanie H., Kucherlapati, Raju S., Baylin, Stephen, Cope, Leslie, Danilova, Ludmila, Bootwalla, Moiz S., Lai, Phillip H., Maglinte, Dennis T., Van Den Berg, David J., Weisenberger, Daniel J., Auman, J. Todd, Balu, Saianand, Bodenheimer, Tom, Fan, Cheng, Hoadley, Katherine A., Hoyle, Alan P., Jefferys, Stuart R., Jones, Corbin D., Meng, Shaowu, Mieczkowski, Piotr A., Mose, Lisle E., Perou, Amy H., Perou, Charles M., Roach, Jeffrey, Shi, Yan, Simons, Janae V., Skelly, Tara, Soloway, Matthew G., Tan, Donghui, Veluvolu, Umadevi, Fan, Huihui, Hinoue, Toshinori, Laird, Peter W., Shen, Hui, Zhou, Wanding, Bellair, Michelle, Chang, Kyle, Covington, Kyle, Creighton, Chad J., Dinh, Huyen, Doddapaneni, HarshaVardhan, Donehower, Lawrence A., Drummond, Jennifer, Gibbs, Richard A., Glenn, Robert, Hale, Walker, Han, Yi, Hu, Jianhong, Korchina, Viktoriya, Lee, Sandra, Lewis, Lora, Li, Wei, Liu, Xiuping, Morgan, Margaret, Morton, Donna, Muzny, Donna, Santibanez, Jireh, Sheth, Margi, Shinbrot, Eve, Wang, Linghua, Wang, Min, Wheeler, David A., Xi, Liu, Zhao, Fengmei, Hess, Julian, Appelbaum, Elizabeth L., Bailey, Matthew, Cordes, Matthew G., Ding, Li, Fronick, Catrina C., Fulton, Lucinda A., Fulton, Robert S., Kandoth, Cyriac, Mardis, Elaine R., McLellan, Michael D., Miller, Christopher A., Schmidt, Heather K., Wilson, Richard K., Crain, Daniel, Curley, Erin, Gardner, Johanna, Lau, Kevin, Mallery, David, Morris, Scott, Paulauskis, Joseph, Penny, Robert, Shelton, Candace, Shelton, Troy, Sherman, Mark, Thompson, Eric, Yena, Peggy, Bowen, Jay, Gastier-Foster, Julie M., Gerken, Mark, Leraas, Kristen M., Lichtenberg, Tara M., Ramirez, Nilsa C., Wise, Lisa, Zmuda, Erik, Corcoran, Niall, Costello, Tony, Hovens, Christopher, Carvalho, Andre L., de Carvalho, Ana C., Fregnani, José H., Longatto-Filho, Adhemar, Reis, Rui M., Scapulatempo-Neto, Cristovam, Silveira, Henrique C.S., Vidal, Daniel O., Burnette, Andrew, Eschbacher, Jennifer, Hermes, Beth, Noss, Ardene, Singh, Rosy, Anderson, Matthew L., Castro, Patricia D., Ittmann, Michael, Huntsman, David, Kohl, Bernard, Le, Xuan, Thorp, Richard, Andry, Chris, Duffy, Elizabeth R., Lyadov, Vladimir, Paklina, Oxana, Setdikova, Galiya, Shabunin, Alexey, Tavobilov, Mikhail, McPherson, Christopher, Warnick, Ronald, Berkowitz, Ross, Cramer, Daniel, Feltmate, Colleen, Horowitz, Neil, Kibel, Adam, Muto, Michael, Raut, Chandrajit P., Malykh, Andrei, Barnholtz-Sloan, Jill S., Barrett, Wendi, Devine, Karen, Fulop, Jordonna, Ostrom, Quinn T., Shimmel, Kristen, Wolinsky, Yingli, Sloan, Andrew E., De Rose, Agostino, Giuliante, Felice, Goodman, Marc, Karlan, Beth Y., Hagedorn, Curt H., Eckman, John, Harr, Jodi, Myers, Jerome, Tucker, Kelinda, Zach, Leigh Anne, Deyarmin, Brenda, Hu, Hai, Kvecher, Leonid, Larson, Caroline, Mural, Richard J., Somiari, Stella, Vicha, Ales, Zelinka, Tomas, Bennett, Joseph, Iacocca, Mary, Rabeno, Brenda, Swanson, Patricia, Latour, Mathieu, Lacombe, Louis, Têtu, Bernard, Bergeron, Alain, McGraw, Mary, Staugaitis, Susan M., Chabot, John, Hibshoosh, Hanina, Sepulveda, Antonia, Su, Tao, Wang, Timothy, Potapova, Olga, Voronina, Olga, Desjardins, Laurence, Mariani, Odette, Roman-Roman, Sergio, Sastre, Xavier, Stern, Marc-Henri, Cheng, Feixiong, Signoretti, Sabina, Berchuck, Andrew, Bigner, Darell, Lipp, Eric, Marks, Jeffrey, McCall, Shannon, McLendon, Roger, Secord, Angeles, Sharp, Alexis, Behera, Madhusmita, Brat, Daniel J., Chen, Amy, Delman, Keith, Force, Seth, Khuri, Fadlo, Magliocca, Kelly, Maithel, Shishir, Olson, Jeffrey J., Owonikoko, Taofeek, Pickens, Alan, Ramalingam, Suresh, Shin, Dong M., Sica, Gabriel, Van Meir, Erwin G., Zhang, Hongzheng, Eijckenboom, Wil, Gillis, Ad, Korpershoek, Esther, Looijenga, Leendert, Oosterhuis, Wolter, Stoop, Hans, van Kessel, Kim E., Zwarthoff, Ellen C., Calatozzolo, Chiara, Cuppini, Lucia, Cuzzubbo, Stefania, DiMeco, Francesco, Finocchiaro, Gaetano, Mattei, Luca, Perin, Alessandro, Pollo, Bianca, Chen, Chu, Houck, John, Lohavanichbutr, Pawadee, Hartmann, Arndt, Stoehr, Christine, Stoehr, Robert, Taubert, Helge, Wach, Sven, Wullich, Bernd, Kycler, Witold, Murawa, Dawid, Wiznerowicz, Maciej, Chung, Ki, Edenfield, W. Jeffrey, Martin, Julie, Baudin, Eric, Bubley, Glenn, Bueno, Raphael, De Rienzo, Assunta, Richards, William G., Kalkanis, Steven, Mikkelsen, Tom, Noushmehr, Houtan, Scarpace, Lisa, Girard, Nicolas, Aymerich, Marta, Campo, Elias, Giné, Eva, Guillermo, Armando López, Van Bang, Nguyen, Hanh, Phan Thi, Phu, Bui Duc, Tang, Yufang, Colman, Howard, Evason, Kimberley, Dottino, Peter R., Martignetti, John A., Gabra, Hani, Juhl, Hartmut, Akeredolu, Teniola, Stepa, Serghei, Hoon, Dave, Ahn, Keunsoo, Kang, Koo Jeong, Beuschlein, Felix, Breggia, Anne, Birrer, Michael, Bell, Debra, Borad, Mitesh, Bryce, Alan H., Castle, Erik, Chandan, Vishal, Cheville, John, Copland, John A., Farnell, Michael, Flotte, Thomas, Giama, Nasra, Ho, Thai, Kendrick, Michael, Kocher, Jean-Pierre, Kopp, Karla, Moser, Catherine, Nagorney, David, O’Brien, Daniel, O’Neill, Brian Patrick, Patel, Tushar, Petersen, Gloria, Que, Florencia, Rivera, Michael, Roberts, Lewis, Smallridge, Robert, Smyrk, Thomas, Stanton, Melissa, Thompson, R. Houston, Torbenson, Michael, Yang, Ju Dong, Zhang, Lizhi, Brimo, Fadi, Ajani, Jaffer A., Gonzalez, Ana Maria Angulo, Behrens, Carmen, Bondaruk, Jolanta, Broaddus, Russell, Czerniak, Bogdan, Esmaeli, Bita, Fujimoto, Junya, Gershenwald, Jeffrey, Guo, Charles, Lazar, Alexander J., Logothetis, Christopher, Meric-Bernstam, Funda, Moran, Cesar, Ramondetta, Lois, Rice, David, Sood, Anil, Tamboli, Pheroze, Thompson, Timothy, Troncoso, Patricia, Tsao, Anne, Wistuba, Ignacio, Carter, Candace, Haydu, Lauren, Hersey, Peter, Jakrot, Valerie, Kakavand, Hojabr, Kefford, Richard, Lee, Kenneth, Long, Georgina, Mann, Graham, Quinn, Michael, Saw, Robyn, Scolyer, Richard, Shannon, Kerwin, Spillane, Andrew, Stretch, Jonathan, Synott, Maria, Thompson, John, Wilmott, James, Al-Ahmadie, Hikmat, Chan, Timothy A., Ghossein, Ronald, Gopalan, Anuradha, Levine, Douglas A., Reuter, Victor, Singer, Samuel, Singh, Bhuvanesh, Tien, Nguyen Viet, Broudy, Thomas, Mirsaidi, Cyrus, Nair, Praveen, Drwiega, Paul, Miller, Judy, Smith, Jennifer, Zaren, Howard, Park, Joong-Won, Hung, Nguyen Phi, Kebebew, Electron, Linehan, W. Marston, Metwalli, Adam R., Pacak, Karel, Pinto, Peter A., Schiffman, Mark, Schmidt, Laura S., Vocke, Cathy D., Wentzensen, Nicolas, Worrell, Robert, Yang, Hannah, Moncrieff, Marc, Goparaju, Chandra, Melamed, Jonathan, Pass, Harvey, Botnariuc, Natalia, Caraman, Irina, Cernat, Mircea, Chemencedji, Inga, Clipca, Adrian, Doruc, Serghei, Gorincioi, Ghenadie, Mura, Sergiu, Pirtac, Maria, Stancul, Irina, Tcaciuc, Diana, Albert, Monique, Alexopoulou, Iakovina, Arnaout, Angel, Bartlett, John, Engel, Jay, Gilbert, Sebastien, Parfitt, Jeremy, Sekhon, Harman, Thomas, George, Rassl, Doris M., Rintoul, Robert C., Bifulco, Carlo, Tamakawa, Raina, Urba, Walter, Hayward, Nicholas, Timmers, Henri, Antenucci, Anna, Facciolo, Francesco, Grazi, Gianluca, Marino, Mirella, Merola, Roberta, de Krijger, Ronald, Gimenez-Roqueplo, Anne-Paule, Piché, Alain, Chevalier, Simone, McKercher, Ginette, Birsoy, Kivanc, Barnett, Gene, Brewer, Cathy, Farver, Carol, Naska, Theresa, Pennell, Nathan A., Raymond, Daniel, Schilero, Cathy, Smolenski, Kathy, Williams, Felicia, Morrison, Carl, Borgia, Jeffrey A., Liptay, Michael J., Pool, Mark, Seder, Christopher W., Junker, Kerstin, Omberg, Larsson, Dinkin, Mikhail, Manikhas, George, Alvaro, Domenico, Bragazzi, Maria Consiglia, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Chesla, David, Cottingham, Sandra, Dubina, Michael, Moiseenko, Fedor, Dhanasekaran, Renumathy, Becker, Karl-Friedrich, Janssen, Klaus-Peter, Slotta-Huspenina, Julia, Abdel-Rahman, Mohamed H., Aziz, Dina, Bell, Sue, Cebulla, Colleen M., Davis, Amy, Duell, Rebecca, Elder, J. Bradley, Hilty, Joe, Kumar, Bahavna, Lang, James, Lehman, Norman L., Mandt, Randy, Nguyen, Phuong, Pilarski, Robert, Rai, Karan, Schoenfield, Lynn, Senecal, Kelly, Wakely, Paul, Hansen, Paul, Lechan, Ronald, Powers, James, Tischler, Arthur, Grizzle, William E., Sexton, Katherine C., Kastl, Alison, Henderson, Joel, Porten, Sima, Waldmann, Jens, Fassnacht, Martin, Asa, Sylvia L., Schadendorf, Dirk, Couce, Marta, Graefen, Markus, Huland, Hartwig, Sauter, Guido, Schlomm, Thorsten, Simon, Ronald, Tennstedt, Pierre, Olabode, Oluwole, Nelson, Mark, Bathe, Oliver, Carroll, Peter R., Chan, June M., Disaia, Philip, Glenn, Pat, Kelley, Robin K., Landen, Charles N., Phillips, Joanna, Prados, Michael, Simko, Jeffry, Smith-McCune, Karen, VandenBerg, Scott, Roggin, Kevin, Fehrenbach, Ashley, Kendler, Ady, Sifri, Suzanne, Steele, Ruth, Jimeno, Antonio, Carey, Francis, Forgie, Ian, Mannelli, Massimo, Carney, Michael, Hernandez, Brenda, Campos, Benito, Herold-Mende, Christel, Jungk, Christin, Unterberg, Andreas, von Deimling, Andreas, Bossler, Aaron, Galbraith, Joseph, Jacobus, Laura, Knudson, Michael, Knutson, Tina, Ma, Deqin, Milhem, Mohammed, Sigmund, Rita, Godwin, Andrew K., Madan, Rashna, Rosenthal, Howard G., Adebamowo, Clement, Adebamowo, Sally N., Boussioutas, Alex, Beer, David, Giordano, Thomas, Mes-Masson, Anne-Marie, Saad, Fred, Bocklage, Therese, Landrum, Lisa, Mannel, Robert, Moore, Kathleen, Moxley, Katherine, Postier, Russel, Walker, Joan, Zuna, Rosemary, Feldman, Michael, Valdivieso, Federico, Dhir, Rajiv, Luketich, James, Pinero, Edna M. Mora, Quintero-Aguilo, Mario, Carlotti, Carlos Gilberto, Jr., Dos Santos, Jose Sebastião, Kemp, Rafael, Sankarankuty, Ajith, Tirapelli, Daniela, Catto, James, Agnew, Kathy, Swisher, Elizabeth, Creaney, Jenette, Robinson, Bruce, Shelley, Carl Simon, Godwin, Eryn M., Kendall, Sara, Shipman, Cassaundra, Bradford, Carol, Carey, Thomas, Haddad, Andrea, Moyer, Jeffey, Peterson, Lisa, Prince, Mark, Rozek, Laura, Wolf, Gregory, Bowman, Rayleen, Fong, Kwun M., Yang, Ian, Korst, Robert, Rathmell, W. Kimryn, Fantacone-Campbell, J. Leigh, Hooke, Jeffrey A., Kovatich, Albert J., Shriver, Craig D., DiPersio, John, Drake, Bettina, Govindan, Ramaswamy, Heath, Sharon, Ley, Timothy, Van Tine, Brian, Westervelt, Peter, Rubin, Mark A., Lee, Jung Il, Aredes, Natália D., Mariamidze, Armaz, Gao, Qingsong, Liang, Wen-Wei, Foltz, Steven M., Mutharasu, Gnanavel, Jayasinghe, Reyka G., Cao, Song, Liao, Wen-Wei, Reynolds, Sheila M., Wyczalkowski, Matthew A., Yao, Lijun, Yu, Lihua, Sun, Sam Q., Chen, Ken, Fields, Ryan C., Wendl, Michael C., Van Tine, Brian A., Vij, Ravi, Chen, Feng, Nykter, Matti

Source: In Cell Reports 3 April 2018 23(1):227-238

Real‐world outcomes of patients with locally advanced or metastatic epithelioid sarcoma

Authors: Gounder, Mrinal M., Merriam, Priscilla, Ratan, Ravin, Patel, Shreyaskumar R., Chugh, Rashmi, Villalobos, Victor M., Thornton, Mark, Van Tine, Brian A., Abdelhamid, Amr H., Whalen, Jennifer, Yang, Jay, Rajarethinam, Anand, Duh, Mei Sheng, Bobbili, Priyanka J., Huynh, Lynn, Totev, Todor I., Lax, Angela K., Agarwal, Shefali, Demetri, George D.

Source: Cancer. 127(8):1311-1317

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122592113.0x000001&indx=1&recIds=ETOCvdc_100122592113.0x000001

Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer

Authors: Jones, Robin L., Herzog, Thomas J., Patel, Shreyaskumar R., von Mehren, Margaret, Schuetze, Scott M., Van Tine, Brian A., Coleman, Robert L., Knoblauch, Roland, Triantos, Spyros, Hu, Peter, Shalaby, Waleed, McGowan, Tracy, Monk, Bradley J., Demetri, George D.

Source: Cancer medicine. 10(11):3565-3574

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122577350.0x000001&indx=1&recIds=ETOCvdc_100122577350.0x000001

A randomized, open‐label, phase 2, multicenter trial of gemcitabine with pazopanib or gemcitabine with docetaxel in patients with advanced soft‐tissue sarcoma

Authors: Somaiah, Neeta, Van Tine, Brian Andrew, Wahlquist, Amy E., Milhem, Mohammed M., Hill, Elizabeth G., Garrett‐Mayer, Elizabeth, Armeson, Kent E., Schuetze, Scott M., Meyer, Christian F., Reuben, Daniel Y., Elias, Anthony D., Read, William L., Chawla, Sant P., Kraft, Andrew S.

Source: Cancer. 127(6):894-904

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116436266.0x000001&indx=1&recIds=ETOCvdc_100116436266.0x000001

Phase II Randomized Study of CMB305 and Atezolizumab Compared With Atezolizumab Alone in Soft-Tissue Sarcomas Expressing NY-ESO-1

Authors: Chawla, Sant P., Van Tine, Brian A., Pollack, Seth M., Ganjoo, Kristen N., Elias, Anthony D., Riedel, Richard F., Attia, Steven, Choy, Edwin, Okuno, Scott H., Agulnik, Mark, von Mehren, Margaret, Livingston, Michael B., Keedy, Vicki L., Verschraegen, Claire F., Philip, Tony, Bohac, G. Chet, Yurasov, Sergey, Yakovich, Adam, Lu, Hailing, Chen, Michael, Maki, Robert G.

Source: Journal of clinical oncology. 40(12):1291-1300

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155645505.0x000001&indx=1&recIds=ETOCvdc_100155645505.0x000001