Safety concern of recombination between self-amplifying mRNA vaccines and viruses is mitigated in vivo

Authors: Hick, Tessy A.H., Geertsema, Corinne, Nguyen, Wilson, Bishop, Cameron R., van Oosten, Linda, Abbo, Sandra R., Dumenil, Troy, van Kuppeveld, Frank J.M., Langereis, Martijn A., Rawle, Daniel J., Tang, Bing, Yan, Kexin, van Oers, Monique M., Suhrbier, Andreas, Pijlman, Gorben P.

Source: In Molecular Therapy 7 August 2024 32(8):2519-2534

Assessment of Kinome-Wide Activity Remodeling upon Picornavirus Infection

Authors: Veth, Tim S., Nouwen, Lonneke V., Zwaagstra, Marleen, Lyoo, Heyrhyoung, Wierenga, Kathryn A., Westendorp, Bart, Altelaar, Maarten A.F.M., Berkers, Celia, van Kuppeveld, Frank J.M., Heck, Albert J.R.

Source: In Molecular & Cellular Proteomics May 2024 23(5)

Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors

Authors: Liu, Mengying, van Kuppeveld, Frank JM, de Haan, Cornelis AM, de Vries, Erik

Source: In Current Opinion in Virology June 2023 60

Move and countermove: the integrated stress response in picorna- and coronavirus-infected cells

Authors: Aloise, Chiara, Schipper, Jelle G ^*, de Groot, Raoul J, van Kuppeveld, Frank JM

Source: In Current Opinion in Immunology December 2022 79

Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters

Authors: de Swart, Rik L., de Leeuw, Olav S., Oreshkova, Nadia, Gerhards, Nora M., Albulescu, Irina C., Vreman, Sandra, Gonzales, José L., Maas, Riks, van Kuppeveld, Frank J.M., Soema, Peter, Bosch, Berend-Jan, Peeters, Ben P.H.

Source: Vaccine. 40(33):4676-4681

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Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region

Authors: Pascha, Mirte N., Thijssen, Vito, Egido, Julia E., Linthorst, Mirte W., van Lanen, Jipke H., van Dongen, David A. A., Hopstaken, Antonius J. P., van Kuppeveld, Frank J. M., Snijder, Joost, de Haan, Cornelis A. M.

Source: ACS chemical biology. 17(9):2425-2436

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630271907&indx=1&recIds=ETOCRN630271907

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

Authors: Lang, Yifei, Li, Wentao, Li, Zeshi, Koerhuis, Danielle, van den Burg, Arthur C. S., Rozemuller, Erik, Bosch, Berend-Jan, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Huizinga, Eric G., van der Schaar, Hilde M., de Groot, Raoul J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Oct . 117(41), 25759-25770.

Access URL: https://www.jstor.org/stable/26969650

Respiratory mucus as a virus-host range determinant

Authors: Wallace, Louisa E., Liu, Mengying, van Kuppeveld, Frank J.M., de Vries, Erik, de Haan, Cornelis A.M.

Source: In Trends in Microbiology November 2021 29(11):983-992

Picornavirus security proteins promote the release of extracellular vesicle enclosed viruses via the modulation of host kinases.

Authors: Defourny, Kyra A. Y.¹, Pei, Xinyi¹, van Kuppeveld, Frank J. M.², Nolte-´t Hoen, Esther N. M.¹, e.n.m.nolte@uu.nl

Source: PLoS Pathogens; 4/25/2024, Vol. 20 Issue 4, p1-23, 23p

Second sialic acid‐binding site of influenza A virus neuraminidase: binding receptors for efficient release

Authors: Du, Wenjuan, de Vries, Erik, van Kuppeveld, Frank J. M., Matrosovich, Mikhail, de Haan, Cornelis A. M.

Source: FEBS journal. 288(19):5598-5612

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Highly pathogenic avian influenza (HPAI) H5 virus exposure in domestic cats and rural stray cats, the Netherlands, October 2020 to June 2023.

Authors: Duijvestijn, Mirjam B. H. M., Schuurman, Nancy N. M. P., Vernooij, Johannes C. M., van Leeuwen, Michelle A. J. M., van den Brand, Judith M. A., Wagenaar, Jaap A., van Kuppeveld, Frank J. M., Egberink, Herman F., de Haan, Cornelis A. M., Verhagen, Josanne H.

Source: Eurosurveillance (15607917); 10/31/2024, Vol. 29 Issue 44, p24-34, 11p

Translation and Replication Dynamics of Single RNA Viruses

Authors: Boersma, Sanne, Rabouw, Huib H., Bruurs, Lucas J.M., Pavlovič, Tonja, van Vliet, Arno L.W., Beumer, Joep, Clevers, Hans, van Kuppeveld, Frank J.M., Tanenbaum, Marvin E.

Source: In Cell 23 December 2020 183(7):1930-1945

Modulation of nucleotide metabolism by picornaviruses.

Authors: Nouwen, Lonneke V.¹, Breeuwsma, Martijn¹, Zaal, Esther A.², van de Lest, Chris H. A.², Buitendijk, Inge¹, Zwaagstra, Marleen¹, Balić, Pascal³, Filippov, Dmitri V.³, Berkers, Celia R.², C.R.Berkers@uu.nl, van Kuppeveld, Frank J. M.¹, C.R.Berkers@uu.nl

Source: PLoS Pathogens; 3/8/2024, Vol. 20 Issue 3, p1-23, 23p

Lipid Droplets Grease Enterovirus Replication

Authors: Belov, George A., van Kuppeveld, Frank J.M.

Source: In Cell Host & Microbe 14 August 2019 26(2):149-151

Human coronaviruses OC43 and HKU1 bind to 9- O -acetylated sialic acids via a conserved receptor-binding site in spike protein domain A

Authors: Hulswit, Ruben J. G., Lang, Yifei, Bakkers, Mark J. G., Li, Wentao, Li, Zeshi, Schouten, Arie, Ophorst, Bram, van Kuppeveld, Frank J. M., Boons, Geert-Jan, Bosch, Berend-Jan, Huizinga, Eric G., de Groot, Raoul J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb 01. 116(7), 2681-2690.

Access URL: https://www.jstor.org/stable/26682949

Small molecule ISRIB suppresses the integrated stress response within a defined window of activation

Authors: Rabouw, Huib H., Langereis, Martijn A., Anand, Aditya A., Visser, Linda J., de Groot, Raoul J., Walter, Peter, van Kuppeveld, Frank J. M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb 01. 116(6), 2097-2102.

Access URL: https://www.jstor.org/stable/26663789

Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as novel antiviral compounds against enterovirus A71 infection

Authors: Ma, Yipeng, Cong, Wenjuan, Huang, Hao, Sun, Liang, Mai, Anh Hung, Boonen, Kurt, Maryam, Wahedi, De Borggraeve, Wim, Luo, Guoan, Liu, Qingfei, Schoofs, Liliane, Van Kuppeveld, Frank, Neyts, Johan, Mirabelli, Carmen, Luyten, Walter

Source: In International Journal of Antimicrobial Agents February 2019 53(2):128-136

Molecular basis for the acid-initiated uncoating of human enterovirus D68

Authors: Liu, Yue, Sheng, Ju, van Vliet, Arno L. W., Buda, Geeta, van Kuppeveld, Frank J. M., Rossmann, Michael G.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Dec . 115(52), E12209-E12217.

Access URL: https://www.jstor.org/stable/26573958

Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility

Authors: Li, Wentao, Hulswit, Ruben J. G., Kenney, Scott P., Widjaja, Ivy, Jung, Kwonil, Alhamo, Moyasar A., van Dieren, Brenda, van Kuppeveld, Frank J. M., Saif, Linda J., Bosch, Berend-Jan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 May . 115(22), E5135-E5143.

Access URL: https://www.jstor.org/stable/26509959

Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein

Authors: Meutiawati, Febrina, Bezemer, Bodine, Strating, Jeroen R.P.M., Overheul, Gijs J., Žusinaite, Eva, van Kuppeveld, Frank J.M., van Cleef, Koen W.R., van Rij, Ronald P.

Source: In Antiviral Research September 2018 157:68-79