Hepatobiliary phase MRI-guided radiofrequency ablation of small hepatocellular carcinomas invisible on precontrast MRI

Authors: Ebel, Sebastian ^{a, ⁎}, Busse, Harald ^{a, 1}, Beeskow, Anne ^a, Meyer, Hans-Jonas ^a, Seehofer, Daniel ^b, Berg, Thomas ^c, van Bömmel, Florian ^c, Veelken, Rhea ^c, Struck, Manuel Florian ^d, Denecke, Timm ^a, Gößmann, Holger ^a

Source: In European Journal of Radiology May 2025 186

Evaluation of prognostic scores in patients with HCC undergoing first-line immunotherapy with atezolizumab and bevacizumab

Authors: Gairing, Simon Johannes ¹, Mildenberger, Philipp ², Gile, Jennifer ³, Artusa, Fabian ⁴, Scheiner, Bernhard ⁵, Leyh, Catherine ⁶, Lieb, Sabine ⁷, Sinner, Friedrich ⁸, Jörg, Vincent ⁹, Fruendt, Thorben ⁹, Himmelsbach, Vera ¹⁰, Abedin, Nada ¹⁰, Sahin, Cennet ¹¹, Böttcher, Katrin ¹², Schuhbaur, Jasmin ¹³, Labuhn, Simon ¹⁴, Korolewicz, James ¹⁵, Fulgenzi, Claudia A.M. ¹⁵, D'Alessio, Antonio ¹⁵, Zanuso, Valentina ^{16, 17}, Hucke, Florian ¹⁸, Röhlen, Natascha ¹⁹, Ben Khaled, Najib ²⁰, Ramadori, Eleonora ²¹, Müller, Lukas ²², Weinmann, Arndt ¹, Kloeckner, Roman ²³, Galle, Peter Robert ¹, Tran, Nguyen H. ³, Venkatesh, Sudhakar K. ²⁴, Teufel, Andreas ^{25, 26}, Ebert, Matthias ^{26, 27}, De Toni, Enrico N. ²⁰, Waldschmidt, Dirk-Thomas ²¹, Marquardt, Jens U. ²⁸, Bettinger, Dominik ¹⁹, Peck-Radosavljevic, Markus ¹⁸, Geier, Andreas ²⁹, Reiter, Florian P. ²⁹, Rimassa, Lorenza ^{16, 17}, Pinato, David J. ^{15, 30}, Roderburg, Christoph ¹⁴, Ettrich, Thomas ¹³, Bitzer, Michael ³¹, Scheble, Veit ³¹, Ehmer, Ursula ¹², Berres, Marie-Luise ¹¹, Finkelmeier, Fabian ¹⁰, Gonzalez-Carmona, Maria Angeles ³², von Felden, Johann ⁹, Schulze, Kornelius ⁹, Venerito, Marino ⁸, van Bömmel, Florian ⁷, Jochheim, Leonie S. ⁶, Pinter, Matthias ⁵, Mohr, Raphael ⁴, Ilyas, Sumera I. ³³, Schmidtmann, Irene ², Foerster, Friedrich ^{1, ⁎}

Source: In JHEP Reports March 2025 7(3)

Real-world effectiveness and safety of bulevirtide monotherapy for up to 96 weeks in patients with HDV-related cirrhosis

Authors: Degasperi, Elisabetta ¹, Anolli, Maria Paola ¹, Jachs, Mathias ², Reiberger, Thomas ², De Ledinghen, Victor ³, Metivier, Sophie ⁴, D’Offizi, Gianpiero ⁵, di Maria, Francesco ⁵, Schramm, Christoph ⁶, Schmidt, Hartmut ⁶, Zöllner, Caroline ⁷, Tacke, Frank ⁷, Dietz-Fricke, Christopher ⁸, Wedemeyer, Heiner ⁸, Papatheodoridi, Margarita ⁹, Papatheodoridis, George ⁹, Carey, Ivana ¹⁰, Agarwal, Kosh ¹⁰, Van Bömmel, Florian ¹¹, Brunetto, Maurizia R. ¹², Cardoso, Mariana ¹³, Verucchi, Gabriella ¹⁴, Ciancio, Alessia ¹⁵, Zoulim, Fabien ¹⁶, Aleman, Soo ¹⁷, Semmo, Nasser ¹⁸, Mangia, Alessandra ¹⁹, Hilleret, Marie-Noelle ²⁰, Merle, Uta ²¹, Santantonio, Teresa A. ²², Coppola, Nicola ²³, Pellicelli, Adriano ²⁴, Roche, Bruno ²⁵, Causse, Xavier ²⁶, D’Alteroche, Louis ²⁷, Dumortier, Jérome ²⁸, Ganne, Nathalie ²⁹, Heluwaert, Frederic ³⁰, Ollivier, Isabelle ³¹, Roulot, Dominique ³², Viganò, Mauro ³³, Loglio, Alessandro ³⁴, Federico, Alessandro ³⁵, Pileri, Francesca ³⁶, Maracci, Monia ³⁷, Tonnini, Matteo ³⁸, Arpurt, Jean-Pierre ³⁹, Barange, Karl ⁴⁰, Billaud, Eric ⁴¹, Pol, Stanislas ⁴², Gervais, Anne ⁴³, Minello, Anne ⁴⁴, Rosa, Isabelle ⁴⁵, Puoti, Massimo ⁴⁶, Lampertico, Pietro ^{1, 47, 48, ⁎}

Source: In Journal of Hepatology December 2024

Evaluation of four chatbots in autoimmune liver disease: A comparative analysis

Authors: Daza, Jimmy, Bezerra, Lucas Soares, Santamaría, Laura, Rueda-Esteban, Roberto, Bantel, Heike, Girala, Marcos, Ebert, Matthias, Van Bömmel, Florian, Geier, Andreas, Aldana, Andres Gomez, Yau, Kevin, Alvares-da-Silva, Mario, Peck-Radosavljevic, Markus, Ridruejo, Ezequiel, Weinmann, Arndt, Teufel, Andreas

Source: In Annals of Hepatology January-February 2025 30(1)

JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analogue-suppressed patients with chronic hepatitis B: REEF-2

Authors: Agarwal, Kosh, Buti, Maria, van Bömmel, Florian, Lampertico, Pietro, Janczewska, Ewa, Bourliere, Marc, Vanwolleghem, Thomas, Lenz, Oliver, Verbinnen, Thierry, Kakuda, Thomas N., Mayer, Cristiana, Jezorwski, John, Muenz, Daniel, Beumont, Maria, Kalmeijer, Ronald, Biermer, Michael, Lonjon-Domanec, Isabelle

Source: In Journal of Hepatology September 2024 81(3):404-414

HBV DNA and HBsAg Levels at 24 Weeks Off-Treatment Predict Clinical Relapse and HBsAg Loss in HBeAg-Negative Patients Who Discontinued Antiviral Therapy

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Janssen, Harry L., Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In Gastroenterology January 2024 166(1):168-177

HBsAg protein composition and clinical outcomes in chronic hepatitis D and variations across HBeAg-negative chronic HBsAg carriers

Authors: Roade, Luisa, Riveiro-Barciela, Mar, Pfefferkorn, Maria, Sopena, Sara, Palom, Adriana, Bes, Marta, Rando-Segura, Ariadna, Casillas, Rosario, Tabernero, David, Rodríguez-Frías, Francisco, Berg, Thomas, Esteban, Rafael, van Bömmel, Florian, Buti, María

Source: In JHEP Reports October 2023 5(10)

Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial

Authors: Bourgeois, Stefan, Vanwolleghem, Thomas, Nevens, Frederik, Horsmans, Yves, Van Vlierberghe, Hans, Nastri, Ana Catharina, Lacerda, Marcus, Ramji, Alnoor, Conway, Brian, Coffin, Carla, Janssen, Harry, Fung, Scott, Shafran, Stephen, Hou, Jin Lin, Sperl, Jan, Urbanek, Petr, Plisek, Stanislav, Hejda, Vaclav, Samuel, Didier, Lacombe, Karine, Zoulim, Fabien, Guyader, Dominique, Raffi, Francois, Asselah, Tarik, Bourliere, Marc, Hilleret, Marie-Noelle, Wedemeyer, Heiner, Schulze zur Wiesch, Julian, Sprinzl, Kathrin, van Boemmel, Florian, Hilgard, Gudrun, Sabranski, Michael, Arasteh, Keikawus, Chan, Henry LY, Yuen, Man Fung, Wong, Vincent Ws, Brunetto, Maurizia Rossana, Taliani, Gloria, Andreone, Pietro, Lampertico, Pietro, Kurosaki, Masayuki, Yatsuhashi, Hiroshi, Fujiwara, Kei, Takehara, Tetsuo, Kawaoka, Tomokazu, Asahina, Yasuhiro, Enomoto, Hirayuki, Yabushita, Kazuhisa, Notsumata, Kazuo, Takaguchi, Koichi, Kawabe, Naoto, Kato, Naoya, Koji, Ogawa, Namisaki, Tadashi, Suzuki, Yoshiyuki, Yoon, Jung-Hwan, Ahn, SangHoon, Lim, Young-Suk, Paik, Seung Woon, Kiew, Kuang Kiat, Mohamed, Rosmawati, Tan, Soek Siam, Lee, Yeong Yeh, Hlebowicz, Maria, Berak, Hanna, Gasiorowski, Jacek, Halota, Waldemar, Janczewska, Ewa, Geyvandova, Natalia, Morozov, Viacheslav, Andreeva, Alla, Gusev, Denis, Bessonova, Elena, Osipenko, Marina, Romanova, Svetlana, Gankina, Natalia, Sagalova, Olga, Stepanova, Tatiana, Crespo Garcia, Javier, Diago, Moises, Inmaculada, Fernandez, Calleja, Jose Luis, Forns, Xavier, Buti, Maria, Tangkijvanich, Pisit, Tanwandee, Tawesak, Piratvisuth, Teerha, Leerapun, Apinya, Yilmaz, Gurdal, Tabak, Ömer Fehmi, Akarca, Ulus Salih, Akova, Murat, Idilman, Ramazan, Forton, Daniel, Bell, David, Agarwal, Kosh, Kennedy, Patrick, Felizarta, Franco, Sulkowski, Mark, Nahass, Ronald, Rojter, Sergio, Jacobson, Ira, Korenblat, Kevin, Gitlin, Norman, Yuen, Man-Fung ^*, Jacobson, Ira M, Janssen, Harry L A, Kakuda, Thomas N, Lambrecht, Tom, Beumont, Maria, Kalmeijer, Ronald, Guinard-Azadian, Carine, Mayer, Cristiana, Jezorwski, John, Verbinnen, Thierry, Lenz, Oliver, Shukla, Umesh, Biermer, Michael

Source: In The Lancet Gastroenterology & Hepatology September 2023 8(9):790-802

Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-negative chronic hepatitis B: A multicentre cohort study

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In JHEP Reports August 2023 5(8)

A multicenter randomized-controlled trial of nucleos(t)ide analogue cessation in HBeAg-negative chronic hepatitis B

Authors: van Bömmel, Florian, Stein, Kerstin, Heyne, Renate, Petersen, Jörg, Buggisch, Peter, Berg, Christoph, Zeuzem, Stefan, Stallmach, Andreas, Sprinzl, Martin, Schott, Eckart, Pathil-Warth, Anita, von Arnim, Ulrike, Keitel, Verena, Lohmeyer, Jürgen, Simon, Karl-Georg, Trautwein, Christian, Trein, Andreas, Hüppe, Dietrich, Cornberg, Markus, Lammert, Frank, Ingiliz, Patrick, Zachoval, Reinhart, Hinrichsen, Holger, Zipprich, Alexander, Klinker, Hartmuth, Schulze zur Wiesch, Julian, Schmiedeknecht, Anett, Brosteanu, Oana, Berg, Thomas

Source: In Journal of Hepatology May 2023 78(5):926-936

End-of-treatment HBsAg, HBcrAg and HBV RNA predict the risk of off-treatment ALT flares in chronic hepatitis B patients

Authors: Brakenhoff, Sylvia M., de Knegt, Robert J., van Campenhout, Margo J.H., van der Eijk, Annemiek A., Brouwer, Willem P., van Bömmel, Florian, Boonstra, André, Hansen, Bettina E., Berg, Thomas, Janssen, Harry L.A., de Man, Robert A., Sonneveld, Milan J.

Source: In Journal of Microbiology, Immunology and Infection February 2023 56(1):31-39

Serum levels of hepatitis B core antibodies and hepatitis B core–related antigen at the time of nucleos(t)ide analog cessation and risk of severe flares in patients with chronic hepatitis B.

Authors: van Bömmel, Florian, Verbinnen, Thierry, Agarwal, Kosh, Vanwolleghem, Thomas, Lampertico, Pietro, Buti, Maria, Janczewska, Ewa, Bourliere, Marc, Jezorwski, John, Donohue, Kathleen, Kim, Gloria, Kakuda, Thomas N., De Meyer, Sandra, Bakala, Adam, Biermer, Michael, Lenz, Oliver

Source: Hepatology Communications; Mar2025, Vol. 9 Issue 3, p1-12, 12p

T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma

Authors: Barsch, Maryam, Salié, Henrike, Schlaak, Alexandra Emilia, Zhang, Zhen, Hess, Moritz, Mayer, Lena Sophie, Tauber, Catrin, Otto-Mora, Patricia, Ohtani, Takuya, Nilsson, Tobias, Wischer, Lara, Winkler, Frances, Manne, Sasikant, Rech, Andrew, Schmitt-Graeff, Annette, Bronsert, Peter, Hofmann, Maike, Neumann-Haefelin, Christoph, Boettler, Tobias, Fichtner-Feigl, Stefan, van Boemmel, Florian, Berg, Thomas, Rimassa, Lorenza, Di Tommaso, Luca, Saeed, Anwaar, D’Alessio, Antonio, Pinato, David J., Bettinger, Dominik, Binder, Harald, John Wherry, E., Schultheiss, Michael, Thimme, Robert, Bengsch, Bertram

Source: In Journal of Hepatology August 2022 77(2):397-409

Probability of HBsAg loss after nucleo(s)tide analogue withdrawal depends on HBV genotype and viral antigen levels

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In Journal of Hepatology May 2022 76(5):1042-1050

Prediction of Sustained Response After Nucleo(s)tide Analogue Cessation Using HBsAg and HBcrAg Levels: A Multicenter Study (CREATE)

Authors: Sonneveld, Milan J., Park, Jun Yong, Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Maasoumy, Benjamin

Source: In Clinical Gastroenterology and Hepatology April 2022 20(4):e784-e793

Predictive performance of newer Asian hepatocellular carcinoma risk scores in treated Caucasians with chronic hepatitis B

Authors: Papatheodoridis, George V., Dalekos, George N., Idilman, Ramazan, Sypsa, Vana, Van Boemmel, Florian, Buti, Maria, Calleja, Jose Luis, Goulis, John, Manolakopoulos, Spilios, Loglio, Alessandro, Papatheodoridi, Margarita, Gatselis, Nikolaos, Veelken, Rhea, Lopez-Gomez, Marta, Hansen, Bettina E., Savvidou, Savvoula, Kourikou, Anastasia, Vlachogiannakos, John, Galanis, Kostas, Yurdaydin, Cihan, Esteban, Rafael, Janssen, Harry L.A., Berg, Thomas, Lampertico, Pietro

Source: In JHEP Reports June 2021 3(3)

Composition of HBsAg is predictive of HBsAg loss during treatment in patients with HBeAg-positive chronic hepatitis B

Authors: Pfefferkorn, Maria, Schott, Tina, Böhm, Stephan, Deichsel, Danilo, Felkel, Christin, Gerlich, Wolfram H., Glebe, Dieter, Wat, Cynthia, Pavlovic, Vedran, Heyne, Renate, Berg, Thomas, van Bömmel, Florian

Source: In Journal of Hepatology February 2021 74(2):283-292

Effects of Protamine Reversal on Coagulation Parameters After High-Dose Heparin Administration in Percutaneous Hepatic Chemosaturation Intervention.

Authors: Metze, Michael, Zimmermann, Silke, Kirsten, Holger, Werdehausen, Robert, Veelken, Rhea, van Bömmel, Florian, Denecke, Timm, Meyer, Hans-Jonas, Ebel, Sebastian, Struck, Manuel Florian

Source: Clinics & Practice; Feb2025, Vol. 15 Issue 2, p38, 12p

Subject Terms: PARTIAL thromboplastin time, BLOOD coagulation, FIBRINOGEN, PLATELET count, HEPARIN, INTERNATIONAL normalized ratio, ARTIFICIAL blood circulation

Early HBcrAg and Anti‐HBc Levels Identify Patients at High Risk for Severe Flares After Nucleos(t)ide Analogue Cessation—A Pooled Analysis of Two Clinical Trials.

Authors: Dongelmans, Edo J., Feld, Jordan J., Boonstra, André, Brakenhoff, Sylvia M., Wong, David, Yim, Colina, Claassen, Mark, Honkoop, Pieter, Hansen, Bettina E., de Man, Robert A., Fung, Scott, Berg, Thomas, van Bömmel, Florian, Janssen, Harry L. A., Sonneveld, Milan J.

Source: Alimentary Pharmacology & Therapeutics; Feb2025, Vol. 61 Issue 3, p570-578, 9p

Subject Terms: END of treatment, LIVER failure, LOGISTIC regression analysis, CLINICAL trials, LONGITUDINAL method

Comparison of CT-Guided Microwave Ablation of Liver Malignancies with and Without Intra-Arterial Catheter Placement for Contrast Administration.

Authors: Beeskow, Anne Bettina, Gößmann, Holger, Meyer, Hans-Jonas, Seehofer, Daniel, Berg, Thomas, van Bömmel, Florian, Schindler, Aaron, Struck, Manuel Florian, Denecke, Timm, Ebel, Sebastian

Source: Current Oncology; Jan2025, Vol. 32 Issue 1, p28, 10p

Subject Terms: CONTRAST media, CATHETERIZATION, HEPATIC artery, LIVER tumors, CATHETERS