Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells

Authors: Valeria Manganelli, Michele Costanzo, Daniela Caissutti, Illari Salvatori, Niccolò Candelise, Emiliano Montalesi, Giovanna De Simone, Alberto Ferri, Tina Garofalo, Maurizio Sorice, Margherita Ruoppolo, Agostina Longo, Roberta Misasi

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

Subject Terms: Neuroglobin, Raptor, Autophagy, Neuroblastoma cells, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0df790c2325e4da8a0e4a1160a4b6096

Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer

Authors: Claudia Duranti, Jessica Iorio, Valeria Manganelli, Giacomo Bagni, Rossella Colasurdo, Tiziano Lottini, Michele Martinelli, Chiara Capitani, Giulia Boso, Franco Nicolas D’Alessandro, Maurizio Sorice, Andrea Becchetti, Roberta Misasi, Tina Garofalo, Annarosa Arcangeli

Source: Cell Death Discovery, Vol 11, Iss 1, Pp 1-20 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/03445f869d8a4b66ab624821a295249f

Wnt signaling as a translational target in rheumatoid and psoriatic arthritis

Authors: Gloria Riitano, Francesca Spinelli, Valeria Manganelli, Daniela Caissutti, Antonella Capozzi, Cristina Garufi, Tina Garofalo, Roberta Misasi, Maurizio Sorice, Fabrizio Conti, Agostina Longo, Cristiano Alessandri

Source: Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-10 (2025)

Subject Terms: Rheumatoid arthritis, Psoriatic arthritis, Wnt signaling, DKK1, β-catenin, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/0665e1e8993840a787badf23bd5d93d6

Extracellular microvesicles from patients with Rheumatoid arthritis promote dendritic cell activation in vitro

Authors: Brigitta Buttari, Serena Recalchi, Gloria Riitano, Antonella Capozzi, Federica Maria Ucci, Valeria Manganelli, Federica Fratini, Elisabetta Profumo, Tina Garofalo, Cristiano Alessandri, Roberta Misasi, Fabrizio Conti, Agostina Longo, Maurizio Sorice

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: rheumatoid arthritis, dendritic cells, extracellular microvesicles, post-translational modifications, cell activation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1532114/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/334b1fa96ead478fa0af2d18f186532d

Lipid rafts mediate multilineage differentiation of human dental pulp-derived stem cells (DPSCs)

Authors: Francesca Santilli, Jessica Fabrizi, Stefano Martellucci, Costantino Santacroce, Egidio Iorio, Maria Elena Pisanu, Mattea Chirico, Loreto Lancia, Fanny Pulcini, Valeria Manganelli, Maurizio Sorice, Simona Delle Monache, Vincenzo Mattei

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: DPSCs, lipid rafts, gangliosides, osteogenic, chondrogenic and adipogenic differentiation, multilineage differentiation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1274462/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/9de5ede52a974011ae4877a651a1d4a7

Antiphospholipid antibodies in patients with stroke during COVID-19: A role in the signaling pathway leading to platelet activation

Authors: Antonella Capozzi, Gloria Riitano, Serena Recalchi, Valeria Manganelli, Agostina Longo, Anne Falcou, Manuela De Michele, Tina Garofalo, Fabio M. Pulcinelli, Maurizio Sorice, Roberta Misasi

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: antiphospholipid antibodies, β2-GPI, COVID-19, thrombosis, stroke., Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1129201/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/55e066f3b315407ea5cf5b6dd849935f

Role of Lipid Rafts on LRP8 Signaling Triggered by Anti-β2-GPI Antibodies in Endothelial Cells

Authors: Gloria Riitano, Antonella Capozzi, Serena Recalchi, Mariaconcetta Augusto, Fabrizio Conti, Roberta Misasi, Tina Garofalo, Maurizio Sorice, Valeria Manganelli

Source: Biomedicines, Vol 11, Iss 12, p 3135 (2023)

Subject Terms: lipid rafts, LRP8, antiphospholipid syndrome, anti-β2-GPI antibodies, cyclodextrins, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/12/3135; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/3f2a17154a5b40b5b6bdd5c5deac9d08

Relationship Between Gender Differences and Clinical Outcome in Patients With the Antiphospholipid Syndrome

Authors: Simona Truglia, Antonella Capozzi, Silvia Mancuso, Valeria Manganelli, Luca Rapino, Gloria Riitano, Serena Recalchi, Serena Colafrancesco, Fulvia Ceccarelli, Tina Garofalo, Cristiano Alessandri, Agostina Longo, Roberta Misasi, Fabrizio Conti, Maurizio Sorice

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: gender, antiphospholipid (Hughes) syndrome, clinical manifestations, antiphospholipid antibodies, thrombosis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.932181/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fa8f7f565b2a4b2e9022d124a57679aa

Role of a Novel Heparanase Inhibitor on the Balance between Apoptosis and Autophagy in U87 Human Glioblastoma Cells

Authors: Valeria Manganelli, Roberta Misasi, Gloria Riitano, Antonella Capozzi, Vincenzo Mattei, Tuba Rana Caglar, Davide Ialongo, Valentina Noemi Madia, Antonella Messore, Roberta Costi, Roberto Di Santo, Maurizio Sorice, Tina Garofalo

Source: Cells, Vol 12, Iss 14, p 1891 (2023)

Subject Terms: heparanase inhibitor, apoptosis, autophagy, U87 human glioblastoma cells, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/14/1891; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/4a6d6815a3b94fd9b93af0311f16cea2

Proteome data of neuroblastoma cells overexpressing Neuroglobin

Authors: Michele Costanzo, Marianna Caterino, Illari Salvatori, Valeria Manganelli, Alberto Ferri, Roberta Misasi, Margherita Ruoppolo

Source: Data in Brief, Vol 41, Iss , Pp 107843- (2022)

Subject Terms: Proteomics, Neuroglobin, Label-free quantification, LC-MS/MS, S-Trap, MaxQuant, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340922000555; https://doaj.org/toc/2352-3409

Access URL: https://doaj.org/article/c811c0cd1c1b4a369f9baaf61c24c0f9

HMGB1 in Pediatric COVID-19 Infection and MIS-C: A Pilot Study

Authors: Laura Petrarca, Valeria Manganelli, Raffaella Nenna, Antonella Frassanito, Shira Ben David, Enrica Mancino, Tina Garofalo, Maurizio Sorice, Roberta Misasi, Fabio Midulla

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: MIS-C multisystem inflammatory syndrome in children, COVID–19, HMGB1 (high mobility group box 1), SARS–CoV2, infection - immunology, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.868269/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/89a0a039ffab485cbed8853fcaf20b27

Signal transduction pathway involved in platelet activation in immune thrombotic thrombocytopenia after COVID-19 vaccination

Authors: Roberta Misasi, Antonella Capozzi, Gloria Riitano, Serena Recalchi, Valeria Manganelli, Vincenzo Mattei, Agostina Longo, Manuela De Michele, Tina Garofalo, Fabio M. Pulcinelli, Maurizio Sorice

Source: Haematologica, Vol 107, Iss 1 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10419; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/493894085608495c97b9a561f2418b52

Targeting Lipid Rafts as a Strategy Against Coronavirus

Authors: Maurizio Sorice, Roberta Misasi, Gloria Riitano, Valeria Manganelli, Stefano Martellucci, Agostina Longo, Tina Garofalo, Vincenzo Mattei

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: coronavirus, SARS-CoV-2, lipid rafts, statins, cyclodextrins, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.618296/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/62c2460cf3b948b282996b51cc884fbc

Anti-β2-GPI Antibodies Induce Endothelial Cell Expression of Tissue Factor by LRP6 Signal Transduction Pathway Involving Lipid Rafts

Authors: Gloria Riitano, Antonella Capozzi, Serena Recalchi, Daniela Caissutti, Agostina Longo, Vincenzo Mattei, Fabrizio Conti, Roberta Misasi, Tina Garofalo, Maurizio Sorice, Valeria Manganelli

Source: Cells, Vol 11, Iss 8, p 1288 (2022)

Subject Terms: antiphospholipid syndrome, β2-GPI-glycoprotein I, LRP-6, Tissue Factor, signal transduction, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/8/1288; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/20ff817c154342ada706393bbed9fba0

Overexpression of Neuroglobin Promotes Energy Metabolism and Autophagy Induction in Human Neuroblastoma SH-SY5Y Cells

Authors: Valeria Manganelli, Illari Salvatori, Michele Costanzo, Antonella Capozzi, Daniela Caissutti, Marianna Caterino, Cristiana Valle, Alberto Ferri, Maurizio Sorice, Margherita Ruoppolo, Tina Garofalo, Roberta Misasi

Source: Cells, Vol 10, Iss 12, p 3394 (2021)

Subject Terms: neuroglobin, mitochondria, autophagy, energy metabolism, SH-SY5Y neuroblastoma cells, label-free proteomics, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/12/3394; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/95fb4d7e4420408aae6bef968400b480

Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

Authors: Antonella Capozzi, Daniela Caissutti, Vincenzo Mattei, Francesca Gado, Stefano Martellucci, Agostina Longo, Serena Recalchi, Valeria Manganelli, Gloria Riitano, Tina Garofalo, Maurizio Sorice, Clementina Manera, Roberta Misasi

Source: Molecules, Vol 27, Iss 1, p 64 (2021)

Subject Terms: CB2R agonist, CB2R, immunomodulation, anti-inflammatory activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/1/64; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/4df138465d51425ab4b50f7f751fac86

Role of ERLINs in the Control of Cell Fate through Lipid Rafts

Authors: Valeria Manganelli, Agostina Longo, Vincenzo Mattei, Serena Recalchi, Gloria Riitano, Daniela Caissutti, Antonella Capozzi, Maurizio Sorice, Roberta Misasi, Tina Garofalo

Source: Cells, Vol 10, Iss 9, p 2408 (2021)

Subject Terms: ERLINs, lipid rafts, MAMs, autophagy, apoptosis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/9/2408; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/4e057583598b43388b8ab7388571b2cd

The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence

Authors: Valeria Manganelli, Antonella Capozzi, Serena Recalchi, Gloria Riitano, Vincenzo Mattei, Agostina Longo, Roberta Misasi, Tina Garofalo, Maurizio Sorice

Source: Biomolecules, Vol 11, Iss 2, p 222 (2021)

Subject Terms: cardiolipin, MAMs, autophagosome, mitochondria, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/11/2/222; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/80df48c7f6cb45dc80d6f32d7b72393c

Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome

Authors: Valeria Manganelli, Simona Truglia, Antonella Capozzi, Cristiano Alessandri, Gloria Riitano, Francesca Romana Spinelli, Fulvia Ceccarelli, Silvia Mancuso, Tina Garofalo, Agostina Longo, Guido Valesini, Maurizio Sorice, Fabrizio Conti, Roberta Misasi

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: HMGB1, sRAGE, antiphospholipid syndrome, thrombosis, recurrent abortion, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00460/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b34d17726acc4a7daca24950266afdac

A Monocentric Cohort of Obstetric Seronegative Anti-Phospholipid Syndrome

Authors: Simona Truglia, Antonella Capozzi, Silvia Mancuso, Serena Recalchi, Francesca Romana Spinelli, Carlo Perricone, Caterina De Carolis, Valeria Manganelli, Gloria Riitano, Tina Garofalo, Agostina Longo, Sara De Carolis, Cristiano Alessandri, Roberta Misasi, Guido Valesini, Maurizio Sorice, Fabrizio Conti

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: anti-phospholipid syndrome, seronegative anti-phospholipid syndrome, anti-vimentin/cardiolipin, thin-layer chromatography, anti-phosphatidylserine/prothrombin, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01678/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/1ab2b2bfeccb4a9a906cc9628a0575eb