Zα Domain of ADAR1 Binds to an A-Form-like Nucleic Acid Duplex with Low Micromolar Affinity

Authors: Nichols, Parker J., Welty, Robb, Krall, Jeffrey B., Henen, Morkos A., Vicens, Quentin, Vögeli, Beat

Source: BIOCHEMISTRY -PENNSYLVANIA THEN WASHINGTON-. 63(6):777-787

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SASH1 S519N Variant Links Skin Hyperpigmentation and Premature Hair Graying to Dysfunction of Melanocyte Lineage

Authors: Lambert, Karoline A. ¹, Clements, Christopher M. ¹, Mukherjee, Nabanita ¹, Pacheco, Theresa R. ¹, Shellman, Samantha X. ², Henen, Morkos A. ³, Vögeli, Beat ³, Goldstein, Nathaniel B. ¹, Birlea, Stanca ^{1, 4}, Hintzsche, Jennifer ⁵, Caryotakis, Griffin ^{6, 7}, Tan, Aik-Choon ^{6, 7}, Zhao, Rui ³, Norris, David A. ¹, Robinson, William A. ⁸, Wang, Yizhou ⁹, VanTreeck, Jillian G. ¹⁰, Shellman, Yiqun G. ^{1, 4, ∗}

Source: In Journal of Investigative Dermatology January 2025 145(1):144-154

Novel Z-DNA binding domains in giant viruses

Authors: Romero, Miguel F., Krall, Jeffrey B., Nichols, Parker J., Vantreeck, Jillian, Henen, Morkos A., Dejardin, Emmanuel, Schulz, Frederik, Vicens, Quentin, Vögeli, Beat, Diallo, Mamadou Amadou

Source: In Journal of Biological Chemistry August 2024 300(8)

Z-RNA biology: a central role in the innate immune response?

Authors: Nichols, Parker J., Krall, Jeffrey B., Henen, Morkos A., Vögeli, Beat, Vicens, Quentin

Source: RNA. 29(3):273-281

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Adoption of A—Z Junctions in RNAs by Binding of Zα Domains

Authors: Nichols, Parker J., Bevers, Shaun, Henen, Morkos A., Kieft, Jeffrey S., Vicens, Quentin, Vögeli, Beat

Source: Methods in molecular biology. 2651:251-276

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An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by β-coronavirus Non-structural Protein 1

Authors: Maurina, Stephanie F., O'Sullivan, John P., Sharma, Geetika, Pineda Rodriguez, Daniel C., MacFadden, Andrea, Cendali, Francesca, Henen, Morkos A., Vögeli, Beat, Kieft, Jeffrey S., Glasgow, Anum, Steckelberg, Anna-Lena

Source: In Journal of Molecular Biology 15 October 2023 435(20)

Proteolytic activation of human-specific Olduvai domains by the furin protease

Authors: Pacheco, Ashley ¹, Issaian, Aaron ¹, Davis, Jonathan, Anderson, Nathan, Nemkov, Travis, Paukovich, Natasia, Henen, Morkos A., Vögeli, Beat, Sikela, James M. ^⁎, Hansen, Kirk ^⁎

Source: In International Journal of Biological Macromolecules 15 April 2023 234

SAM1 domain of SASH1 harbors distinctive structural heterogeneity

Authors: Clements, Christopher M., Vögeli, Beat, Shellman, Yiqun G., Henen, Morkos A.

Source: In Journal of Structural Biology December 2022 214(4)

Advances in the exact nuclear Overhauser effect 2018–2022

Authors: Hussain, Alya, Paukovich, Natasia, Henen, Morkos A., Vögeli, Beat

Source: In Methods October 2022 206:87-98

The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region

Authors: Redzic, Jasmina S., Lee, Eunjeong, Born, Alexandra, Issaian, Aaron, Henen, Morkos A., Nichols, Parker J., Blue, Ashley, Hansen, Kirk C., D'Alessandro, Angelo, Vögeli, Beat, Eisenmesser, Elan Zohar

Source: In Journal of Molecular Biology 23 July 2021 433(15)

The Disordered Spindly C-terminus Interacts with RZZ Subunits ROD-1 and ZWL-1 in the Kinetochore through the Same Sites in C. Elegans

Authors: Henen, Morkos A., Myers, Walter, Schmitt, Lauren R., Wade, Kristen J., Born, Alexandra, Nichols, Parker J., Vögeli, Beat

Source: In Journal of Molecular Biology 19 February 2021 433(4)

Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance

Authors: Born, Alexandra, Soetbeer, Janne, Breitgoff, Frauke, Henen, Morkos A., Sgourakis, Nikolaos, Polyhach, Yevhen, Nichols, Parker J., Strotz, Dean, Jeschke, Gunnar, Vögeli, Beat

Source: Journal of the American Chemical Society. 143(39):16055-16067

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Solution NMR backbone assignment of the N-terminal tandem Zα1-Zα2 domains of Z-DNA binding protein 1.

Authors: Beck, Lily G., Krall, Jeffrey B., Nichols, Parker J., Vicens, Quentin, Henen, Morkos A., Vögeli, Beat

Source: Biomolecular NMR Assignments; Dec2024, Vol. 18 Issue 2, p245-252, 8p

Protein Motional Details Revealed by Complementary Structural Biology Techniques

Authors: Grohe, Kristof, Patel, Snehal, Hebrank, Cornelia, Medina, Sara, Klein, Alexander, Rovó, Petra, Vasa, Suresh K., Singh, Himanshu, Vögeli, Beat, Schäfer, Lars V., Linser, Rasmus

Source: In Structure 1 September 2020 28(9):1024-1034

Protein Allostery at Atomic Resolution

Authors: Strotz, Dean, Orts, Julien, Kadavath, Harindranath, Friedmann, Michael, Ghosh, Dhiman, Olsson, Simon, Chi, Celestine N., Pokharna, Aditya, Güntert, Peter, Vögeli, Beat, Riek, Roland

Source: Angewandte Chemie. 132(49):22316-22323

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Deuteration of nonexchangeable protons on proteins affects their thermal stability, side‐chain dynamics, and hydrophobicity

Authors: Nichols, Parker J., Falconer, Isaac, Griffin, Aaron, Mant, Colin, Hodges, Robert, McKnight, Christopher J., Vögeli, Beat, Vugmeyster, Liliya

Source: Protein science. 29(7):1641-1654

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Reducing the measurement time of exact NOEs by non-uniform sampling

Authors: Nichols, Parker J., Born, Alexandra, Henen, Morkos A., Strotz, Dean, Jones, David N., Delaglio, Frank, Vögeli, Beat

Source: Journal of biomolecular NMR. 74(12):717-739

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Exact distance measurements for structure and dynamics in solid proteins by fast-magic-angle-spinning NMRElectronic supplementary information (ESI) available. See DOI: 10.1039/c9cc02317h

Authors: Grohe, Kristof, Nimerovsky, Evgeny, Singh, Himanshu, Vasa, Suresh K., Söldner, Benedikt, Vögeli, Beat, Rienstra, Chad M., Linser, Rasmus

Source: Chemical communications. 55(55):7899-7902

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Solution NMR backbone assignment reveals interaction-free tumbling of human lineage-specific Olduvai protein domains

Authors: Issaian, Aaron, Schmitt, Lauren, Born, Alexandra, Nichols, Parker J., Sikela, James, Hansen, Kirk, Vögeli, Beat, Henen, Morkos A.

Source: Biomolecular NMR assignments. 13(2):339-343

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Structural Investigation of a Putative Intrinsically Disordered Region Within Deleted in Colorectal Carcinoma That Regulates Protein Synthesis

Authors: Nowling, Nathan L., Spear, Elizabeth A., Paukovich, Natasia, Manalastas, John, Vögeli, Beat, Filbin, Megan E.

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196446579.0x000001&indx=1&recIds=ETOCvdc_100196446579.0x000001