Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing

Authors: Mendel, Mateusz, Delaney, Kamila, Pandey, Radha Raman, Chen, Kuan-Ming, Wenda, Joanna M., Vågbø, Cathrine Broberg, Steiner, Florian A., Homolka, David, Pillai, Ramesh S.

Source: In Cell 10 June 2021 184(12):3125-3142

RNA in DNA repair

Authors: Vågbø, Cathrine Broberg, Slupphaug, Geir

Source: In DNA Repair November 2020 95

Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility

Authors: Dohnalkova, Michaela, Krasnykov, Kyrylo, Mendel, Mateusz, Li, Lingyun, Panasenko, Olesya, Fleury-Olela, Fabienne, Vågbø, Cathrine Broberg, Homolka, David, Pillai, Ramesh S.

Source: Cell reports. 42(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194797739.0x000001&indx=1&recIds=ETOCvdc_100194797739.0x000001

Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification

Authors: Monies, Dorota, Vågbø, Cathrine Broberg, Al-Owain, Mohammad, Alhomaidi, Suzan, Alkuraya, Fowzan S.

Source: American journal of human genetics. 104(6):1202-1209

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093392449.0x000001&indx=1&recIds=ETOCvdc_100093392449.0x000001

Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens.

Authors: Ravn Berg, Sigrid, Dikic, Aida, Sharma, Animesh, Hagen, Lars, Vågbø, Cathrine Broberg, Zatula, Alexey, Misund, Kristine, Waage, Anders, Slupphaug, Geir

Source: Journal of Translational Medicine; 6/7/2024, Vol. 22 Issue 1, p1-24, 24p

Subject Terms: CELL surface antigens, MULTIPLE myeloma, QUALITY control, PLASMA cells, CANCER cells

M^6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

Authors: Ke, Shengdong, Pandya-Jones, Amy, Saito, Yuhki, Fak, John J., Vågbø, Cathrine Broberg, Geula, Shay, Hanna, Jacob H., Black, Douglas L., Darnell, James E., Darnell, Robert B.

Source: Genes & development. 31(10):990-1006

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612177439&indx=1&recIds=ETOCRN612177439

The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues

Authors: Pandey, Radha Raman, Delfino, Elena, Homolka, David, Roithova, Adriana, Chen, Kuan-Ming, Li, Lingyun, Franco, Giulia, Vågbø, Cathrine Broberg, Taillebourg, Emmanuel, Fauvarque, Marie-Odile, Pillai, Ramesh S.

Source: Cell reports. 32(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117049370.0x000001&indx=1&recIds=ETOCvdc_100117049370.0x000001

Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response

Authors: Vågbø, Cathrine Broberg, Svaasand, Eva K., Aas, Per A., Krokan, Hans E.

Source: In DNA Repair 1 March 2013 12(3):188-195

5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication

Authors: Prikrylova, Terezia, Robertson, Julia, Ferrucci, Francesca, Konorska, Dorota, Aanes, Håvard, Manaf, Adeel, Zhang, Beibei, Vågbø, Cathrine Broberg, Kuśnierczyk, Anna, Gilljam, Karin M., Løvkvam-Køster, Caroline, Otterlei, Marit, Dahl, John Arne, Enserink, Jorrit, Klungland, Arne, Robertson, Adam B.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131458206.0x000001&indx=1&recIds=ETOCvdc_100131458206.0x000001

Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA

Authors: Westbye, Marianne Pedersen, Feyzi, Emadoldin, Aas, Per Arne, Vågbø, Cathrine Broberg, Talstad, Vivi Anita, Kavli, Bodil, Hagen, Lars, Sundheim, Ottar, Akbari, Mansour, Liabakk, Nina-Beate, Slupphaug, Geir, Otterlei, Marit, Krokan, Hans Einar

Source: In Journal of Biological Chemistry 5 September 2008 283(36):25046-25056

Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.

Authors: Maddirevula, Sateesh, Alameer, Seham, Ewida, Nour, de Sousa, Mirta Mittelstedt Leal, Bjørås, Magnar, Vågbø, Cathrine Broberg, Alkuraya, Fowzan S

Source: Human Genetics; Feb2022, Vol. 141 Issue 2, p209-215, 7p

Subject Terms: DEVELOPMENTAL disabilities, INTELLECTUAL disabilities, TRANSFER RNA, CHILDREN with developmental disabilities, MISSENSE mutation, PROTEIN expression, URIDINE, METHYLTRANSFERASES

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The Human Base Excision Repair Enzyme SMUG1 Directly Interacts with DKC1 and Contributes to RNA Quality Control

Authors: Jobert, Laure, Skjeldam, Hanne K., Dalhus, Bjørn, Galashevskaya, Anastasia, Vågbø, Cathrine Broberg, Bjørås, Magnar, Nilsen, Hilde

Source: In Molecular Cell 24 January 2013 49(2):339-345

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m⁶A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.

Authors: Shengdong Ke^1,2, Pandya-Jones, Amy³, Yuhki Saito^1,2, Fak, John J.^1,2, Vågbø, Cathrine Broberg⁴, Geula, Shay⁵, Hanna, Jacob H.⁵, Black, Douglas L.³, Darnell Jr., James E.⁶, Darnell, Robert B.^1,2, darnell@rockefeller.edudarnelr@rockefeller.edu

Source: Genes & Development; May2017, Vol. 31 Issue 10, p990-1006, 17p

AlkB demethylases flip out in different ways

Authors: Sundheim, Ottar, Talstad, Vivi A., Vågbø, Cathrine Broberg, Slupphaug, Geir, Krokan, Hans E.

Source: In DNA Repair 1 November 2008 7(11):1916-1923

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Insights into the Mechanisms of Ifosfamide Encephalopathy:Drug Metabolites Have Agonistic Effects on α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA)/Kainate Receptors and Induce Cellular Acidification in Mouse Cortical Neurons

Authors: Chatton, Jean-Yves, Idle, Jeffrey R., Vågbø, Cathrine Broberg, Magistretti, Pierre J.

Source: The Journal of Pharmacology and Experimental Therapeutics; December 2001, Vol. 299 Issue: 3 p1161-1168, 8p