Ym1 protein crystals promote type 2 immunity

Authors: Ines Heyndrickx, Kim Deswarte, Kenneth Verstraete, Koen HG Verschueren, Ursula Smole, Helena Aegerter, Ann Dansercoer, Hamida Hammad, Savvas N Savvides, Bart N Lambrecht

Source: eLife, Vol 12 (2024)

Subject Terms: adjuvanticity, protein crystals, Ym1, Ym2, chitinase-like proteins, Charcot-Leyden crystals, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/90676; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/027f2b940e04436392626839d4f1ade4

The small molecule inhibitor BX-795 uncouples IL-2 production from inhibition of Th2 inflammation and induces CD4+ T cells resembling iTreg

Authors: Peter A. Tauber, Bernhard Kratzer, Philipp Schatzlmaier, Ursula Smole, Cordula Köhler, Lisa Rausch, Jan Kranich, Doris Trapin, Alina Neunkirchner, Maja Zabel, Sabrina Jutz, Peter Steinberger, Gabriele Gadermaier, Thomas Brocker, Hannes Stockinger, Sophia Derdak, Winfried F. Pickl

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: Immunomodulation, IL-2, regulatory T cells, small molecule inhibitor, allergy, Th2 cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1094694/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/00251fce79eb4bce8c93560542f17e14

Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice

Authors: Alina Neunkirchner, Bernhard Kratzer, Cordula Köhler, Ursula Smole, Lukas F. Mager, Klaus G. Schmetterer, Doris Trapin, Victoria Leb-Reichl, Edward Rosloniec, Ronald Naumann, Lukas Kenner, Beatrice Jahn-Schmid, Barbara Bohle, Rudolf Valenta, Winfried F. Pickl

Source: EBioMedicine, Vol 31, Iss , Pp 66-78 (2018)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396418301221; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/8e31910cdc3d426b80e39fd13f80ce89

The major birch pollen allergen Bet v 1 induces different responses in dendritic cells of birch pollen allergic and healthy individuals.

Authors: Ursula Smole, Christian Radauer, Nina Lengger, Martin Svoboda, Neil Rigby, Merima Bublin, Sonja Gaier, Karin Hoffmann-Sommergruber, Erika Jensen-Jarolim, Diana Mechtcheriakova, Heimo Breiteneder

Source: PLoS ONE, Vol 10, Iss 1, p e0117904 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/040e5c0b42054d63a2a97a6b991a4730

Specificity of mimotope-induced anti-high molecular weight-melanoma associated antigen (HMW-MAA) antibodies does not ensure biological activity.

Authors: Julia Latzka, Sonja Gaier, Gerlinde Hofstetter, Nina Balazs, Ursula Smole, Soldano Ferrone, Otto Scheiner, Heimo Breiteneder, Hubert Pehamberger, Stefan Wagner

Source: PLoS ONE, Vol 6, Iss 5, p e19383 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3089623?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c3ceba15b6764baca67ec0ad6d35e469